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Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

STEM and males

Males A, Nettleship JE, Ren J, Stuart DI.
GSID: RLhj-jyBnqsJ
J Ren, JE Nettleship, A Males, DI Stuart… - FEBS letters, 2016 - Wiley Online Library

… PBP3 and other penicillin-binding proteins are inhibited by β-lactam antibiotics which act as suicide substrates [2, 3] by mimicking the D-alanyl-D-alanine stem peptide of the …

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Ren, J., Nettleship, J. E., Males, A., Stuart, D. I., & Owens, R. J. (2016). Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. FEBS letters, 590(2), 288-297.
Ren, Jingshan, et al. "Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms." FEBS letters 590.2 (2016): 288-297.
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A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library.

Frontiers in microbiology

Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y.
PMID: 27242757
Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016.

Although currently recommended antibiotics for Lyme disease such as doxycycline or amoxicillin cure the majority of the patients, about 10-20% of patients treated for Lyme disease may experience lingering symptoms including fatigue, pain, or joint and muscle aches. Under...

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Feng J, Shi W, Zhang S, et al. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016;7:743doi: 10.3389/fmicb.2016.00743.
Feng, J., Shi, W., Zhang, S., Sullivan, D., Auwaerter, P. G., & Zhang, Y. (2016). A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Frontiers in microbiology, 7743. https://doi.org/10.3389/fmicb.2016.00743
Feng, Jie, et al. "A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library." Frontiers in microbiology vol. 7 (2016): 743. doi: https://doi.org/10.3389/fmicb.2016.00743
Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016. PMID: 27242757; PMCID: PMC4876775.
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Distribution and resistance of pathogens in liver transplant recipients with Acinetobacter baumannii infection.

Therapeutics and clinical risk management

Gao F, Ye Q, Wan Q, Liu S, Zhou J.
PMID: 25848296
Ther Clin Risk Manag. 2015 Mar 26;11:501-5. doi: 10.2147/TCRM.S82251. eCollection 2015.

BACKGROUND: Drug-resistant Acinetobacter baumannii has become a major problem in liver transplant recipients. The aim of this study was to investigate the clinical presentation, distribution, and drug susceptibility characteristics in liver recipients with A. baumannii infection.METHODS: We retrospectively investigated...

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Gao F, Ye Q, Wan Q, et al. Distribution and resistance of pathogens in liver transplant recipients with Acinetobacter baumannii infection. Ther Clin Risk Manag. 2015;11:501-5doi: 10.2147/TCRM.S82251.
Gao, F., Ye, Q., Wan, Q., Liu, S., & Zhou, J. (2015). Distribution and resistance of pathogens in liver transplant recipients with Acinetobacter baumannii infection. Therapeutics and clinical risk management, 11501-5. https://doi.org/10.2147/TCRM.S82251
Gao, Fei, et al. "Distribution and resistance of pathogens in liver transplant recipients with Acinetobacter baumannii infection." Therapeutics and clinical risk management vol. 11 (2015): 501-5. doi: https://doi.org/10.2147/TCRM.S82251
Gao F, Ye Q, Wan Q, Liu S, Zhou J. Distribution and resistance of pathogens in liver transplant recipients with Acinetobacter baumannii infection. Ther Clin Risk Manag. 2015 Mar 26;11:501-5. doi: 10.2147/TCRM.S82251. eCollection 2015. PMID: 25848296; PMCID: PMC4381901.
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Detection of AmpC β-lactamase producing bacteria isolated in neonatal sepsis.

Pakistan journal of medical sciences

Salamat S, Ejaz H, Zafar A, Javed H.
PMID: 28083055
Pak J Med Sci. 2016 Nov-Dec;32(6):1512-1516. doi: 10.12669/pjms.326.10861.

OBJECTIVE: The objective of this study was to determine the occurrence and antimicrobial profile of AmpC β-lactamase producing bacteria.METHODS: The study was conducted at The Children's Hospital and The Institute of Child Health Lahore, Pakistan, during September 2011 to...

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Salamat S, Ejaz H, Zafar A, et al. Detection of AmpC β-lactamase producing bacteria isolated in neonatal sepsis. Pak J Med Sci. 2016;32(6):1512-1516doi: 10.12669/pjms.326.10861.
Salamat, S., Ejaz, H., Zafar, A., & Javed, H. (2016). Detection of AmpC β-lactamase producing bacteria isolated in neonatal sepsis. Pakistan journal of medical sciences, 32(6), 1512-1516. https://doi.org/10.12669/pjms.326.10861
Salamat, Sonia, et al. "Detection of AmpC β-lactamase producing bacteria isolated in neonatal sepsis." Pakistan journal of medical sciences vol. 32,6 (2016): 1512-1516. doi: https://doi.org/10.12669/pjms.326.10861
Salamat S, Ejaz H, Zafar A, Javed H. Detection of AmpC β-lactamase producing bacteria isolated in neonatal sepsis. Pak J Med Sci. 2016 Nov-Dec;32(6):1512-1516. doi: 10.12669/pjms.326.10861. PMID: 28083055; PMCID: PMC5216311.
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ESBL and MBL in Cefepime Resistant Pseudomonas aeruginosa: An Update from a Rural Area in Northern India.

Journal of clinical and diagnostic research : JCDR

Kotwal A, Biswas D, Kakati B, Singh M.
PMID: 27190800
J Clin Diagn Res. 2016 Apr;10(4):DC09-11. doi: 10.7860/JCDR/2016/18016.7612. Epub 2016 Apr 01.

INTRODUCTION: Cefepime, a fourth generation cephalosporin, is widely used for the empirical treatment of serious infections in critically ill hospitalized patients. Pseudomonas aeruginosa (P. aeruginosa), one of the commonest bacteria causing nosocomial infections has a propensity to develop antibiotic...

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Kotwal A, Biswas D, Kakati B, et al. ESBL and MBL in Cefepime Resistant Pseudomonas aeruginosa: An Update from a Rural Area in Northern India. J Clin Diagn Res. 2016;10(4):DC09-11doi: 10.7860/JCDR/2016/18016.7612.
Kotwal, A., Biswas, D., Kakati, B., & Singh, M. (2016). ESBL and MBL in Cefepime Resistant Pseudomonas aeruginosa: An Update from a Rural Area in Northern India. Journal of clinical and diagnostic research : JCDR, 10(4), DC09-11. https://doi.org/10.7860/JCDR/2016/18016.7612
Kotwal, Aarti, et al. "ESBL and MBL in Cefepime Resistant Pseudomonas aeruginosa: An Update from a Rural Area in Northern India." Journal of clinical and diagnostic research : JCDR vol. 10,4 (2016): DC09-11. doi: https://doi.org/10.7860/JCDR/2016/18016.7612
Kotwal A, Biswas D, Kakati B, Singh M. ESBL and MBL in Cefepime Resistant Pseudomonas aeruginosa: An Update from a Rural Area in Northern India. J Clin Diagn Res. 2016 Apr;10(4):DC09-11. doi: 10.7860/JCDR/2016/18016.7612. Epub 2016 Apr 01. PMID: 27190800; PMCID: PMC4866098.
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A Clinico-Bacteriological Study of Pyodermas at a Tertiary Health Center in Southwest Rajasthan.

Indian journal of dermatology

Singh A, Gupta LK, Khare AK, Mittal A, Kuldeep CM, Balai M.
PMID: 26538696
Indian J Dermatol. 2015 Sep-Oct;60(5):479-84. doi: 10.4103/0019-5154.164368.

BACKGROUND: The spectrum of pyoderma changes constantly, and so does the antibiotic susceptibility pattern.AIMS: This study was done to assess the magnitude and clinical patterns of pyodermas, their causative micro-organisms, and the antibiotic susceptibility patterns.MATERIALS AND METHODS: Five hundred...

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Singh A, Gupta LK, Khare AK, et al. A Clinico-Bacteriological Study of Pyodermas at a Tertiary Health Center in Southwest Rajasthan. Indian J Dermatol. 2015;60(5):479-84doi: 10.4103/0019-5154.164368.
Singh, A., Gupta, L. K., Khare, A. K., Mittal, A., Kuldeep, C. M., & Balai, M. (2015). A Clinico-Bacteriological Study of Pyodermas at a Tertiary Health Center in Southwest Rajasthan. Indian journal of dermatology, 60(5), 479-84. https://doi.org/10.4103/0019-5154.164368
Singh, Ajit, et al. "A Clinico-Bacteriological Study of Pyodermas at a Tertiary Health Center in Southwest Rajasthan." Indian journal of dermatology vol. 60,5 (2015): 479-84. doi: https://doi.org/10.4103/0019-5154.164368
Singh A, Gupta LK, Khare AK, Mittal A, Kuldeep CM, Balai M. A Clinico-Bacteriological Study of Pyodermas at a Tertiary Health Center in Southwest Rajasthan. Indian J Dermatol. 2015 Sep-Oct;60(5):479-84. doi: 10.4103/0019-5154.164368. PMID: 26538696; PMCID: PMC4601416.
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Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine.

mSphere

Theriot CM, Bowman AA, Young VB.
PMID: 27239562
mSphere. 2016 Jan 06;1(1). doi: 10.1128/mSphere.00045-15. eCollection 2016.

It is hypothesized that the depletion of microbial members responsible for converting primary bile acids into secondary bile acids reduces resistance to Clostridium difficile colonization. To date, inhibition of C. difficile growth by secondary bile acids has only been...

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Theriot CM, Bowman AA, Young VB. Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere. 2016;1(1)doi: 10.1128/mSphere.00045-15.
Theriot, C. M., Bowman, A. A., & Young, V. B. (2016). Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere, 1(1), . https://doi.org/10.1128/mSphere.00045-15
Theriot, Casey M, et al. "Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine." mSphere vol. 1,1 (2016). doi: https://doi.org/10.1128/mSphere.00045-15
Theriot CM, Bowman AA, Young VB. Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere. 2016 Jan 06;1(1). doi: 10.1128/mSphere.00045-15. eCollection 2016. PMID: 27239562; PMCID: PMC4863611.
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Comparative antibiogram of coagulase-negative Staphylococci (CNS) associated with subclinical and clinical mastitis in dairy cows.

Veterinary world

Bansal BK, Gupta DK, Shafi TA, Sharma S.
PMID: 27047108
Vet World. 2015 Mar;8(3):421-6. doi: 10.14202/vetworld.2015.421-426. Epub 2015 Mar 28.

AIM: The present study was planned to determine the in vitro antibiotic susceptibility of coagulase-negative Staphylococci (CNS) strains isolated from clinical and subclinical cases of mastitis in dairy cows. Antibiotic sensitivity profile will be helpful to recommend early therapy...

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Bansal BK, Gupta DK, Shafi TA, et al. Comparative antibiogram of coagulase-negative Staphylococci (CNS) associated with subclinical and clinical mastitis in dairy cows. Vet World. 2015;8(3):421-6doi: 10.14202/vetworld.2015.421-426.
Bansal, B. K., Gupta, D. K., Shafi, T. A., & Sharma, S. (2015). Comparative antibiogram of coagulase-negative Staphylococci (CNS) associated with subclinical and clinical mastitis in dairy cows. Veterinary world, 8(3), 421-6. https://doi.org/10.14202/vetworld.2015.421-426
Bansal, B K, et al. "Comparative antibiogram of coagulase-negative Staphylococci (CNS) associated with subclinical and clinical mastitis in dairy cows." Veterinary world vol. 8,3 (2015): 421-6. doi: https://doi.org/10.14202/vetworld.2015.421-426
Bansal BK, Gupta DK, Shafi TA, Sharma S. Comparative antibiogram of coagulase-negative Staphylococci (CNS) associated with subclinical and clinical mastitis in dairy cows. Vet World. 2015 Mar;8(3):421-6. doi: 10.14202/vetworld.2015.421-426. Epub 2015 Mar 28. PMID: 27047108; PMCID: PMC4774854.
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Antibiotic sensitivity pattern in blaNDM-1-positive and carbapenemase-producing Enterobacteriaceae.

International journal of applied & basic medical research

Mulla S, Charan J, Rajdev S.
PMID: 26958516
Int J Appl Basic Med Res. 2016 Jan-Mar;6(1):14-7. doi: 10.4103/2229-516X.173989.

BACKGROUND: Some studies published in recent time revealed that many bacteria from Enterobacteriaceae group are multi-antibiotic-resistant because of the production enzymes carbapenemase particularly New Delhi metallo-beta-lactamase encoded by gene called blaNDM-1. Looking at public health importance of this issue...

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Mulla S, Charan J, Rajdev S. Antibiotic sensitivity pattern in blaNDM-1-positive and carbapenemase-producing Enterobacteriaceae. Int J Appl Basic Med Res. 2016;6(1):14-7doi: 10.4103/2229-516X.173989.
Mulla, S., Charan, J., & Rajdev, S. (2016). Antibiotic sensitivity pattern in blaNDM-1-positive and carbapenemase-producing Enterobacteriaceae. International journal of applied & basic medical research, 6(1), 14-7. https://doi.org/10.4103/2229-516X.173989
Mulla, Summaiya, et al. "Antibiotic sensitivity pattern in blaNDM-1-positive and carbapenemase-producing Enterobacteriaceae." International journal of applied & basic medical research vol. 6,1 (2016): 14-7. doi: https://doi.org/10.4103/2229-516X.173989
Mulla S, Charan J, Rajdev S. Antibiotic sensitivity pattern in blaNDM-1-positive and carbapenemase-producing Enterobacteriaceae. Int J Appl Basic Med Res. 2016 Jan-Mar;6(1):14-7. doi: 10.4103/2229-516X.173989. PMID: 26958516; PMCID: PMC4765267.
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Antimicrobial susceptibility pattern in diabetic foot ulcer: a pilot study.

Annals of medical and health sciences research

Sekhar S, Vyas N, Unnikrishnan M, Rodrigues G, Mukhopadhyay C.
PMID: 25328786
Ann Med Health Sci Res. 2014 Sep;4(5):742-5. doi: 10.4103/2141-9248.141541.

BACKGROUND: Diabetic foot infections (DFIs) are major public health problems and knowledge of microbes that cause infections are helpful to determine proper antibiotic therapy.AIMS: The aim was to investigate the antimicrobial susceptibility pattern of microbes in DFIs.SUBJECTS AND METHODS:...

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Sekhar S, Vyas N, Unnikrishnan M, et al. Antimicrobial susceptibility pattern in diabetic foot ulcer: a pilot study. Ann Med Health Sci Res. 2014;4(5):742-5doi: 10.4103/2141-9248.141541.
Sekhar, S., Vyas, N., Unnikrishnan, M., Rodrigues, G., & Mukhopadhyay, C. (2014). Antimicrobial susceptibility pattern in diabetic foot ulcer: a pilot study. Annals of medical and health sciences research, 4(5), 742-5. https://doi.org/10.4103/2141-9248.141541
Sekhar, Sm, et al. "Antimicrobial susceptibility pattern in diabetic foot ulcer: a pilot study." Annals of medical and health sciences research vol. 4,5 (2014): 742-5. doi: https://doi.org/10.4103/2141-9248.141541
Sekhar S, Vyas N, Unnikrishnan M, Rodrigues G, Mukhopadhyay C. Antimicrobial susceptibility pattern in diabetic foot ulcer: a pilot study. Ann Med Health Sci Res. 2014 Sep;4(5):742-5. doi: 10.4103/2141-9248.141541. PMID: 25328786; PMCID: PMC4199167.
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Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital.

Annals of clinical microbiology and antimicrobials

Gonlugur U, Bakici MZ, Ozdemir L, Akkurt I, Icagasioglu S, Gultekin F.
PMID: 12665428
Ann Clin Microbiol Antimicrob. 2003 Mar 07;2:5. doi: 10.1186/1476-0711-2-5.

BACKGROUND: Lower respiratory tract infections due to Pseudomonas aeruginosa have a high mortality rate. Antibacterial activity of various antibiotics against P. aeruginosa isolated from each hospital depends on the variety or amount of antibiotics used in each hospital.METHOD: A...

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Gonlugur U, Bakici MZ, Ozdemir L, et al. Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital. Ann Clin Microbiol Antimicrob. 2003;2:5doi: 10.1186/1476-0711-2-5.
Gonlugur, U., Bakici, M. Z., Ozdemir, L., Akkurt, I., Icagasioglu, S., & Gultekin, F. (2003). Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital. Annals of clinical microbiology and antimicrobials, 25. https://doi.org/10.1186/1476-0711-2-5
Gonlugur, Ugur, et al. "Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital." Annals of clinical microbiology and antimicrobials vol. 2 (2003): 5. doi: https://doi.org/10.1186/1476-0711-2-5
Gonlugur U, Bakici MZ, Ozdemir L, Akkurt I, Icagasioglu S, Gultekin F. Retrospective analysis of antibiotic susceptibility patterns of respiratory isolates of Pseudomonas aeruginosa in a Turkish University Hospital. Ann Clin Microbiol Antimicrob. 2003 Mar 07;2:5. doi: 10.1186/1476-0711-2-5. PMID: 12665428; PMCID: PMC152644.
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Hypersensitivity vasculitis induced by cefoperazone/sulbactam.

Annals of clinical microbiology and antimicrobials

Islek I, Baris S, Katranci AO, Ariturk E, Gurses N.
PMID: 12556245
Ann Clin Microbiol Antimicrob. 2003 Jan 03;2:1. doi: 10.1186/1476-0711-2-1.

BACKGROUND: Cefoperazone has not been reported to cause vasculitic complications before. Here, we report a case of hypersensitivity vasculitis associated with cefoperazone/sulbactam.CASE PRESENTATION: A 13-year-old girl with appendicitis developed hypersensitivity vasculitis on the fifth day of cefoperazone/sulbactam therapy. Hypersensitivity...

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Islek I, Baris S, Katranci AO, et al. Hypersensitivity vasculitis induced by cefoperazone/sulbactam. Ann Clin Microbiol Antimicrob. 2003;2:1doi: 10.1186/1476-0711-2-1.
Islek, I., Baris, S., Katranci, A. O., Ariturk, E., & Gurses, N. (2003). Hypersensitivity vasculitis induced by cefoperazone/sulbactam. Annals of clinical microbiology and antimicrobials, 21. https://doi.org/10.1186/1476-0711-2-1
Islek, Ismail, et al. "Hypersensitivity vasculitis induced by cefoperazone/sulbactam." Annals of clinical microbiology and antimicrobials vol. 2 (2003): 1. doi: https://doi.org/10.1186/1476-0711-2-1
Islek I, Baris S, Katranci AO, Ariturk E, Gurses N. Hypersensitivity vasculitis induced by cefoperazone/sulbactam. Ann Clin Microbiol Antimicrob. 2003 Jan 03;2:1. doi: 10.1186/1476-0711-2-1. PMID: 12556245; PMCID: PMC149382.
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Showing 1 to 12 of 179 entries