Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 35 entries
Sorted by: Best Match Show Resources per page
Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?.

The Korean journal of pain

Chang EJ, Choi EJ, Kim KH.
PMID: 27413479
Korean J Pain. 2016 Jul;29(3):153-7. doi: 10.3344/kjp.2016.29.3.153. Epub 2016 Jul 01.

Tapentadol is a novel oral analgesic with a dual mode of action as an agonist of the µ-opioid receptor (MOR), and as a norepinephrine reuptake inhibitor (NRI) all in a single molecule. Immediate release (IR) tapentadol shows its analgesic...

Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker.

Oman medical journal

Shakeer SK, Kalapati B, Al Abri SA, Al Busaidi M.
PMID: 31110633
Oman Med J. 2019 May;34(3):244-248. doi: 10.5001/omj.2019.46.

Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available. We report a...

Association of Therapies With Reduced Pain and Improved Quality of Life in Patients With Fibromyalgia: A Systematic Review and Meta-analysis.

JAMA internal medicine

Mascarenhas RO, Souza MB, Oliveira MX, Lacerda AC, Mendonça VA, Henschke N, Oliveira VC.
PMID: 33104162
JAMA Intern Med. 2021 Jan 01;181(1):104-112. doi: 10.1001/jamainternmed.2020.5651.

IMPORTANCE: Fibromyalgia is a chronic condition that results in a significant burden to individuals and society.OBJECTIVE: To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) in people with fibromyalgia.DATA SOURCES: Searches were performed...

Risk of respiratory depression with opioids and concomitant gabapentinoids.

Journal of pain research

Savelloni J, Gunter H, Lee KC, Hsu C, Yi C, Edmonds KP, Furnish T, Atayee RS.
PMID: 29180889
J Pain Res. 2017 Nov 10;10:2635-2641. doi: 10.2147/JPR.S144963. eCollection 2017.

INTRODUCTION: The combination of opioids and central nervous system depressants such as benzodiazepines and barbiturates has an additive effect on the frequency of oversedation and respiratory depression requiring naloxone use in hospitalized patients. Gabapentinoids (gabapentin and pregabalin) are frequently...

Development and Application of a Measurement Framework to Evaluate Safe, Effective and Efficient Medication Use Among Older Adults.

Drugs - real world outcomes

Vyas A, Patry E, Owens N, Belviso N, Kogut SJ.
PMID: 31456064
Drugs Real World Outcomes. 2019 Dec;6(4):173-181. doi: 10.1007/s40801-019-00162-x.

BACKGROUND: A majority of older adults in the United States (US) use prescription medications. Comprehensive population-level approaches to examine medication safety, effectiveness, and costs among older adults are needed.OBJECTIVES: The objectives of this study were to develop a framework...

Substance-Induced Psychosis.

Seminars in clinical neuropsychiatry

Bacon A, Granholm E, Withers N.
PMID: 10085193
Semin Clin Neuropsychiatry. 1998 Jan;3(1):70-79.

Intoxication and withdrawal from a variety of central nervous system depressants and stimulants may induce hallucinations or delusions, which, when unaccompanied by insight, are the hallmarks of psychosis. A substance-induced psychosis may, in many instances, present as an organic...

Missed Opportunities for Sedation and Pain Management at a Level III Neonatal Intensive Care Unit, India.

Frontiers in pediatrics

Kothari SY, Dongara AR, Nimbalkar SM, Phatak AG, Nimbalkar AS.
PMID: 26942166
Front Pediatr. 2016 Feb 23;4:7. doi: 10.3389/fped.2016.00007. eCollection 2016.

BACKGROUND: Neonates in the neonatal intensive care unit (NICU) undergo a multitude of painful and stressful procedures during the first days of life. Stress from this pain can lead to neurodevelopmental problems that manifest in later childhood and should...

Opioid analgesics increase incidence of somnolence and dizziness as adverse effects of pregabalin: a retrospective study.

Journal of pharmaceutical health care and sciences

Ohishi A, Chisaki Y, Hira D, Nagasawa K, Terada T.
PMID: 26819741
J Pharm Health Care Sci. 2015 Dec 01;1:30. doi: 10.1186/s40780-015-0032-5. eCollection 2015.

BACKGROUND: Pregabalin, a gabapentinoid, is an adjuvant analgesic for treatment of neuropathic pain, but it has serious adverse effects such as somnolence and dizziness, particularly in elderly patients. Although decreased renal function is considered to the contributing factor for...

Challenges of Drug-Facilitated Sexual Assault.

Forensic science review

LeBeau MA, Montgomery MA.
PMID: 26242451
Forensic Sci Rev. 2010 Jan;22(1):1-6.

This article provides the reader with an understanding of the numerous challenges of drug-facilitated sexual assaults (DFSA). The challenges are categorized as follows: the drugs, reporting the crime, evidence collection, and laboratory analysis of specimens. The challenges associated with...

History of Respiratory Stimulants.

Journal of pain research

Peppin JF, Pergolizzi JV, Fudin J, Meyer TA, Raffa RB.
PMID: 33889020
J Pain Res. 2021 Apr 16;14:1043-1049. doi: 10.2147/JPR.S298607. eCollection 2021.

The interest in substances that stimulate respiration has waxed and waned throughout the years, intensifying following the introduction of a new class of drugs that causes respiratory depression, and diminishing when antidotes or better drug alternatives are found. Examples...

Driving under the Influence of Flualprazolam: 11 Case Reports.

Journal of analytical toxicology

Mercurio N, Triebold C, Coleman D.
PMID: 34529082
J Anal Toxicol. 2021 Sep 16; doi: 10.1093/jat/bkab105. Epub 2021 Sep 16.

Eleven cases of suspected driving under the influence (DUI) of flualprazolam are presented. Data from police reports and drug recognition examinations (DRE), when available, were evaluated. In all cases, significant driving impairments were observed including weaving, driving slowly, stopping...

Opioid toxicity due to CNS depressant polypharmacy: A case report.

The mental health clinician

Lee C, Wanson A, Frangou S, Chong D, Halpape K.
PMID: 33850686
Ment Health Clin. 2021 Mar 31;11(2):70-74. doi: 10.9740/mhc.2021.03.070. eCollection 2021 Mar.

The interaction between methadone and central nervous system depressants can cause serious adverse effects, including profound sedation, respiratory depression, coma, and death. This poses a challenge in the treatment of patients with concurrent psychiatric and substance use disorders as...

Showing 1 to 12 of 35 entries