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Showing 1 to 12 of 151 entries
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The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer.

The journal of pathology. Clinical research

Ling A, Lundberg IV, Eklöf V, Wikberg ML, Öberg Å, Edin S, Palmqvist R.
PMID: 27499912
J Pathol Clin Res. 2015 Oct 28;2(1):21-31. doi: 10.1002/cjp2.31. eCollection 2016 Jan.

Giving strong prognostic information, T-cell infiltration is on the verge of becoming an additional component in the routine clinical setting for classification of colorectal cancer (CRC). With a view to further improving the tools for prognostic evaluation, we have...

Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells.

Scientific reports

Deshpande NP, Wilkins MR, Castaño-Rodríguez N, Bainbridge E, Sodhi N, Riordan SM, Mitchell HM, Kaakoush NO.
PMID: 27677841
Sci Rep. 2016 Sep 28;6:34288. doi: 10.1038/srep34288.

The epithelial response to the opportunistic pathogen Campylobacter concisus is poorly characterised. Here, we assessed the intestinal epithelial responses to two C. concisus strains with different virulence characteristics in Caco-2 cells using RNAseq, and validated a subset of the...

Involvement of the CXCL12 System in the Stimulatory Effects of Prenatal Exposure to High-Fat Diet on Hypothalamic Orexigenic Peptides and Behavior in Offspring.

Frontiers in behavioral neuroscience

Poon K, Barson JR, Shi H, Chang GQ, Leibowitz SF.
PMID: 28567007
Front Behav Neurosci. 2017 May 17;11:91. doi: 10.3389/fnbeh.2017.00091. eCollection 2017.

Exposure to a high fat diet (HFD) during gestation stimulates neurogenesis and expression of hypothalamic orexigenic neuropeptides that affect consummatory and emotional behaviors. With recent studies showing a HFD to increase inflammation, this report investigated the neuroinflammatory chemokine, CXCL12,...

CSF B - lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis.

Journal of neurology

Ljøstad U, Mygland Å.
PMID: 27517589
J Neurol. 2008 May;255(5):782. doi: 10.1007/s00415-008-0974-8. Epub 2008 Mar 17.

Recent studies have suggested a diagnostic role of the B-lymphocyte attracting chemokine (CXCL13) in the cerebrospinal fluid (CSF) in Lyme neuroborreliosis (LNB). Our aim was to evaluate diagnostic accuracy of CSF CXCL13 in a cohort of 59 consecutive patients...

CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas.

Acta histochemica et cytochemica

Suzuki H, Yamamoto T.
PMID: 26855449
Acta Histochem Cytochem. 2015 Dec 25;48(6):173-8. doi: 10.1267/ahc.15016. Epub 2015 Nov 10.

Immunohistochemical techniques were employed to investigate the distribution of the chemokine CXCL14, in the mouse pancreas. CXCL14-immunoreactive cells were detected in the peripheral region of the pancreatic islets and were immunoreactive for somatostatin, but not for glucagon, insulin, and...

Expression and function of CXCR7 in the mouse forebrain.

Journal of neuroimmunology

Tiveron MC, Boutin C, Daou P, Moepps B, Cremer H.
PMID: 20965095
J Neuroimmunol. 2010 Jun 05; doi: 10.1016/j.jneuroim.2010.05.011. Epub 2010 Jun 05.

The chemokine CXCL12/CXCR4 signaling system is important for the regulation of neuron migration in the developing forebrain. In particular it is crucial for correct distribution of Cajal-Retzius cells and migration of cortical interneurons. Here we investigated the expression of...

Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans.

International journal of inflammation

Segers D, Lipton JA, Leenen PJ, Cheng C, Tempel D, Pasterkamp G, Moll FL, de Crom R, Krams R.
PMID: 22164344
Int J Inflam. 2011;2011:936109. doi: 10.4061/2011/936109. Epub 2011 Nov 13.

Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(-/-) mice, we induced...

A case of relapsing-remitting neuroborreliosis? Challenges in the differential diagnosis of recurrent myelitis.

Case reports in neurology

Albrecht P, Henke N, Lehmann HC, Macht S, Hefter H, Goebels N, Mackenzie C, Rupprecht TA, Fingerle V, Hartung HP, Methner A.
PMID: 22649342
Case Rep Neurol. 2012 Jan;4(1):47-53. doi: 10.1159/000337223. Epub 2012 Mar 14.

We report the case of a 31-year-old woman with 4 episodes of myelitis with pleocytosis, a positive Borrelia burgdorferi serology with positive antibody indices, and full recovery each time after antibiotic and steroid treatment, suggesting neuroborreliosis. We nevertheless believe...

Lower circulating levels of chemokine CXCL10 in Helicobacter pylori-infected patients with peptic ulcer: Influence of the bacterial virulence factor CagA.

Iranian journal of microbiology

Jafarzadeh A, Nemati M, Rezayati MT, Khoramdel H, Nabizadeh M, Hassanshahi G, Abdollahi H.
PMID: 23467184
Iran J Microbiol. 2013 Mar;5(1):28-35.

BACKGROUND AND OBJECTIVES: Alterations in CXCL10 (a Th1 chemokine) expression have been associated with various diseases. The aim of this study was to evaluate the serum CXCL10 levels in H. pylori-infected patients with peptic ulcer (PU), H. pylori-infected asymptomatic...

Protein expression and gene polymorphism of CXCL10 in patients with colorectal cancer.

Biomedical reports

Dimberg J, Skarstedt M, Löfgren S, Zar N, Matussek A.
PMID: 24748971
Biomed Rep. 2014 May;2(3):340-343. doi: 10.3892/br.2014.255. Epub 2014 Mar 17.

Chemokines (chemotactic cytokines) promote leukocyte attraction to sites of inflammation and cancer. Certain chemokines promote and regulate neoplastic progression, including metastasis and angiogenesis. One such chemokine, CXCL10, was found to be expressed in colorectal cancer (CRC) tissue. To gain...

Elevated Expression of Chemokine CXCL13 in Chronic Hepatitis B Patients Links to Immune Control during Antiviral Therapy.

Frontiers in immunology

Liu C, Huang X, Werner M, Broering R, Ge J, Li Y, Liao B, Sun J, Peng J, Lu M, Hou J, Zhang X.
PMID: 28386259
Front Immunol. 2017 Mar 23;8:323. doi: 10.3389/fimmu.2017.00323. eCollection 2017.

C-X-C-chemokine ligand 13 (CXCL13), the ligand for C-X-C chemokine receptor type 5 (CXCR5), is a major regulator of B-cell trafficking and plays an integral role in age-dependent clearance of hepatitis B virus (HBV) in the mouse model. However, the...

Evaluation of chemokine CXCL10 in human gingival crevicular fluid, saliva, and serum as periodontitis biomarker.

Journal of inflammation research

Aldahlawi S, Youssef AR, Shahabuddin S.
PMID: 30464571
J Inflamm Res. 2018 Oct 31;11:389-396. doi: 10.2147/JIR.S177188. eCollection 2018.

PURPOSE: The aim of this study was to evaluate CXCL10 as a biomarker for periodontitis by determining the CXCL10 levels in saliva, serum, and gingival crevicular fluid (GCF) samples from periodontally healthy control subjects and adult subjects with chronic...

Showing 1 to 12 of 151 entries