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Showing 1 to 12 of 48 entries
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Trends in Glaucoma Medication Expenditures under Universal Health Coverage: A National Population-Based Longitudinal Survey in Taiwan.

Journal of ophthalmology

Chiu SL, Chu CL, Muo CH, Chen CL, Lan SJ.
PMID: 26137315
J Ophthalmol. 2015;2015:243401. doi: 10.1155/2015/243401. Epub 2015 Jun 02.

Medical care in Taiwan is well known for its low cost, high efficiency, high quality, excellent medical accessibility, and high equity. We investigate the trends in medication expenditures for glaucoma from 1997 to 2010. The results show that higher...

Differential effects of direct and indirectly acting cholinergic agonists on growth hormone release in man, and lack of effect on cortisol secretion.

Journal of neuroendocrinology

Casanueva FF, Villanueva L, Cordido F, Diaz Y, Cabranes JA, Spiegel R, Dieguez C.
PMID: 19210431
J Neuroendocrinol. 1989 Oct 01;1(5):379-82. doi: 10.1111/j.1365-2826.1989.tb00132.x.

Abstract Acetylcholine plays a key role in the modulation of growth hormone secretion. In fact, growth hormone release after provocative stimuli is blocked by muscarinic cholinergic antagonists, and conversely, indirect cholinergic agonists potentiate growth hormone secretion. To further understand...

A BRIEF REVIEW ON THE MODE OF ACTION OF ANTINEMATODAL DRUGS.

Acta veterinaria

Abongwa M, Martin RJ, Robertson AP.
PMID: 29416226
Acta Vet (Beogr). 2017 Jun;67(2):137-152. doi: 10.1515/acve-2017-0013. Epub 2017 Jun 26.

Anthelmintics are some of the most widely used drugs in veterinary medicine. Here we review the mechanism of action of these compounds on nematode parasites. Included are the older classes of compounds; the benzimidazoles, cholinergic agonists and macrocyclic lactones....

Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10.

Frontiers in cellular neuroscience

Zakrzewicz A, Richter K, Agné A, Wilker S, Siebers K, Fink B, Krasteva-Christ G, Althaus M, Padberg W, Hone AJ, McIntosh JM, Grau V.
PMID: 28725182
Front Cell Neurosci. 2017 Jul 05;11:189. doi: 10.3389/fncel.2017.00189. eCollection 2017.

Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits. Furthermore, we identified phosphocholine (PC) and dipalmitoylphosphatidylcholine (DPPC)...

The cholinergic system in joint health and osteoarthritis: a narrative-review.

Osteoarthritis and cartilage

Lauwers M, Courties A, Sellam J, Wen C.
PMID: 33609692
Osteoarthritis Cartilage. 2021 May;29(5):643-653. doi: 10.1016/j.joca.2021.02.005. Epub 2021 Feb 17.

Osteoarthritis (OA) poses a major health and economic burden worldwide due to an increasing number of patients and the unavailability of disease-modifying drugs. In this review, the latest understanding of the involvement of the cholinergic system in joint homeostasis...

Role of the Cholinergic Anti-Inflammatory Reflex in Central Nervous System Diseases.

International journal of molecular sciences

Ramos-Martínez IE, Rodríguez MC, Cerbón M, Ramos-Martínez JC, Ramos-Martínez EG.
PMID: 34948222
Int J Mol Sci. 2021 Dec 14;22(24). doi: 10.3390/ijms222413427.

In several central nervous system diseases, it has been reported that inflammation may be related to the etiologic process, therefore, therapeutic strategies are being implemented to control inflammation. As the nervous system and the immune system maintain close bidirectional...

A Review on Newer Ocular Drug Delivery Systems with an Emphasis on Glaucoma.

Advanced pharmaceutical bulletin

Peter M, Panonnummal R.
PMID: 34513615
Adv Pharm Bull. 2021 May;11(3):399-413. doi: 10.34172/apb.2021.048. Epub 2020 Sep 19.

Glaucoma is an irreversible condition resulting from the increase in intraocular pressure (IOP); which leads to permanent loss of vision with the destruction of retinal ganglion cells (RGCs). The IOP elevations are controlled in normal by the physiological flow...

Acetylcholine Release Inhibits Distinct Excitatory Inputs Onto Hippocampal CA1 Pyramidal Neurons via Different Cellular and Network Mechanisms.

Frontiers in cellular neuroscience

Goswamee P, McQuiston AR.
PMID: 31249513
Front Cell Neurosci. 2019 Jun 12;13:267. doi: 10.3389/fncel.2019.00267. eCollection 2019.

In hippocampal CA1, muscarinic acetylcholine (ACh) receptor (mAChR) activation via exogenous application of cholinergic agonists has been shown to presynaptically inhibit Schaffer collateral (SC) glutamatergic inputs in stratum radiatum (SR), and temporoammonic (TA) and thalamic nucleus reuniens (RE) glutamatergic...

Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman.

Neuropharmacology

Reddy DS, Zaayman M, Kuruba R, Wu X.
PMID: 33878303
Neuropharmacology. 2021 Jun 15;191:108571. doi: 10.1016/j.neuropharm.2021.108571. Epub 2021 Apr 18.

Status epilepticus (SE) is a medical emergency with continuous seizure activity that causes profound neuronal damage, morbidity, or death. SE incidents can arise spontaneously but mostly are elicited by seizurogenic triggers. Chemoconvulsants such as the muscarinic agonist pilocarpine and,...

MOTOR NEURONES OF THE CRAYFISH WALKING SYSTEM POSSESS TEA+-REVEALED REGENERATIVE ELECTRICAL PROPERTIES.

The Journal of experimental biology

Cattaert D, Araque A, Buno W, Clarac F.
PMID: 9317925
J Exp Biol. 1994 Mar;188(1):339-45.

In crustaceans, some motor neurones (MNs) have been shown to be part of the central pattern generator in the stomatogastric system (Harris-Warrick et al. 1992; Moulins, 1990), the swimmeret system (Heitler, 1978) or the walking system (Chrachri and Clarac,...

The effect on vasopressin release of microinjection of cholinergic agonists into the paraventricular nucleus of conscious rats.

Journal of neuroendocrinology

Shoji M, Share L, Crofton JT, Brooks DP.
PMID: 19210408
J Neuroendocrinol. 1989 Dec 01;1(6):401-6. doi: 10.1111/j.1365-2826.1989.tb00138.x.

Abstract We have studied in conscious unrestrained rats under basal conditions the effect of activation of muscarinic and nicotinic receptors in the paraventricular nucleus on vasopressin secretion and mean arterial blood pressure. The microinjection of oxotremorine (0.2, 2 or...

Comparison of the miotic effects of dapiprazole and dilute pilocarpine in patients with the pigment dispersion syndrome.

Journal of glaucoma

Haynes WL, Thompson HS, Johnson AT, Alward WL.
PMID: 19920703
J Glaucoma. 1995 Dec;4(6):379-85.

PURPOSE: Pharmacologically induced miosis can inhibit exercise-induced anterior chamber pigment dispersion in patients with the pigment dispersion syndrome. Long-term inhibition of pigment dispersion in these patients could delay or prevent the development of glaucoma. Unfortunately, most commercially available miotic...

Showing 1 to 12 of 48 entries