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Manipulation of two regulatory genes for efficient production of chromomycins in .

Journal of biological engineering

Sun L, Zeng J, Cui P, Wang W, Yu D, Zhan J.
PMID: 29977332
J Biol Eng. 2018 Jun 07;12:9. doi: 10.1186/s13036-018-0103-x. eCollection 2018.

BACKGROUND: Regulatory genes play critical roles in natural product biosynthetic pathways. Chromomycins are promising anticancer natural products from actinomycetes. This study is aimed to create an efficient strain for production of these molecules by manipulating the regulatory genes.RESULTS: A...

Cite
Sun L, Zeng J, Cui P, et al. Manipulation of two regulatory genes for efficient production of chromomycins in . J Biol Eng. 2018;12:9doi: 10.1186/s13036-018-0103-x.
Sun, L., Zeng, J., Cui, P., Wang, W., Yu, D., & Zhan, J. (2018). Manipulation of two regulatory genes for efficient production of chromomycins in . Journal of biological engineering, 129. https://doi.org/10.1186/s13036-018-0103-x
Sun, Lei, et al. "Manipulation of two regulatory genes for efficient production of chromomycins in ." Journal of biological engineering vol. 12 (2018): 9. doi: https://doi.org/10.1186/s13036-018-0103-x
Sun L, Zeng J, Cui P, Wang W, Yu D, Zhan J. Manipulation of two regulatory genes for efficient production of chromomycins in . J Biol Eng. 2018 Jun 07;12:9. doi: 10.1186/s13036-018-0103-x. eCollection 2018. PMID: 29977332; PMCID: PMC5992853.
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Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins.

Frontiers in chemistry

Sahm BDB, Peres J, Rezende-Teixeira P, Santos EA, Branco PC, Bauermeister A, Kimani S, Moreira EA, Bisi-Alves R, Bellis C, Mlaza M, Jimenez PC, Lopes NP, Machado-Santelli GM, Prince S, Costa-Lotufo LV.
PMID: 32195221
Front Chem. 2020 Mar 03;8:110. doi: 10.3389/fchem.2020.00110. eCollection 2020.

The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly, based on compelling biological evidences,...

Cite
Sahm BDB, Peres J, Rezende-Teixeira P, et al. Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins. Front Chem. 2020;8:110doi: 10.3389/fchem.2020.00110.
Sahm, B. D. B., Peres, J., Rezende-Teixeira, P., Santos, E. A., Branco, P. C., Bauermeister, A., Kimani, S., Moreira, E. A., Bisi-Alves, R., Bellis, C., Mlaza, M., Jimenez, P. C., Lopes, N. P., Machado-Santelli, G. M., Prince, S., & Costa-Lotufo, L. V. (2020). Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins. Frontiers in chemistry, 8110. https://doi.org/10.3389/fchem.2020.00110
Sahm, Bianca Del B, et al. "Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins." Frontiers in chemistry vol. 8 (2020): 110. doi: https://doi.org/10.3389/fchem.2020.00110
Sahm BDB, Peres J, Rezende-Teixeira P, Santos EA, Branco PC, Bauermeister A, Kimani S, Moreira EA, Bisi-Alves R, Bellis C, Mlaza M, Jimenez PC, Lopes NP, Machado-Santelli GM, Prince S, Costa-Lotufo LV. Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins. Front Chem. 2020 Mar 03;8:110. doi: 10.3389/fchem.2020.00110. eCollection 2020. PMID: 32195221; PMCID: PMC7062867.
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Showing 1 to 2 of 2 entries