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Showing 1 to 12 of 146 entries
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HPV Carcinomas in Immunocompromised Patients.

Journal of clinical medicine

Reusser NM, Downing C, Guidry J, Tyring SK.
PMID: 26239127
J Clin Med. 2015 Jan 29;4(2):260-81. doi: 10.3390/jcm4020260.

Human papillomavirus (HPV) infection is the most common sexually transmitted disease worldwide and can result in pre-malignancies or overt malignancies of the skin and mucosal surfaces. HPV-related illnesses are an important personal and public health problem causing physical, mental,...

Advancements in Pharmacotherapy for Noncancerous Manifestations of HPV.

Journal of clinical medicine

Kollipara R, Ekhlassi E, Downing C, Guidry J, Lee M, Tyring SK.
PMID: 26239450
J Clin Med. 2015 Apr 24;4(5):832-46. doi: 10.3390/jcm4050832.

Human papillomavirus (HPV) is the most common sexually transmitted disease. Via infection of the basal epithelial cells, HPV causes numerous malignancies and noncancerous cutaneous manifestations. Noncancerous cutaneous manifestations of HPV, including common, plantar, plane, and anogenital warts, are among...

Cerebral microsporidiosis manifesting as progressive multifocal leukoencephalopathy in an HIV-infected individual - a case report.

AIDS research and therapy

Loignon M, Labrecque LG, Bard C, Robitaille Y, Toma E.
PMID: 25057277
AIDS Res Ther. 2014 Jul 15;11:20. doi: 10.1186/1742-6405-11-20. eCollection 2014.

Microsporidia have become increasingly recognized as opportunistic pathogens since the genesis of the AIDS epidemic. The incidence of microsporidiosis has decreased with the advent of combination antiretroviral therapy but it is frequently reported in non-HIV immunosuppressed patients and as...

Cytomegalovirus Treatment.

Current treatment options in infectious diseases

Tan BH.
PMID: 25999800
Curr Treat Options Infect Dis. 2014;6(3):256-270. doi: 10.1007/s40506-014-0021-5.

In treating cytomegalovirus (CMV) infection, it is crucial to decide whether one is treating pre-emptively or if one is treating established disease. Disease may be further divided into viral syndrome and tissue-invasive disease. Generally, mild disease in immunosuppressed patients...

Progressive multifocal leukoencephalopathy.

Current treatment options in neurology

Aksamit AJ.
PMID: 18579021
Curr Treat Options Neurol. 2008 May;10(3):178-85. doi: 10.1007/s11940-008-0019-8.

Treatment of progressive multifocal leukoencephalopathy (PML) in a patient with exogenous immunosuppression starts with discontinuation of immunosuppressive medication. The restored host immunity will clear JC virus, the cause of PML, from the brain via cell-mediated immune mechanisms. Patients with...

Dual therapy with cidofovir and mirtazapine for progressive multifocal leukoencephalopathy in a sarcoidosis patient.

Case reports in neurology

Park JH, Ryoo S, Noh HJ, Seo JM, Kang HH, Shin JS, Seo SW, Na DL.
PMID: 22114583
Case Rep Neurol. 2011 Sep;3(3):258-62. doi: 10.1159/000333780. Epub 2011 Oct 14.

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) is a demyelinating central nervous system disease caused by JC virus (JCV) reactivation in immunocompromised patients. The disease course of PML is often progressive, fatal and at present, there are few reports on successful...

Topical cidofovir for treatment of resistant viral infections.

International journal of pharmaceutical compounding

McElhiney LF.
PMID: 23974309
Int J Pharm Compd. 2006 Sep-Oct;10(5):324-8.

Cidofovir is a broad-spectrum antiviral agent with activity against several DNA viruses. An application to approve the use of topical cidofovir for acyclovir-resistant herpes virus infection was denied by the US Food and Drug Administration owing to the lack...

Effect of combinations of antiviral drugs on herpes simplex encephalitis.

Drug design, development and therapy

Gebhardt BM, Focher F, Eberle R, Manikowski A, Wright GE.
PMID: 20054446
Drug Des Devel Ther. 2009 Dec 29;3:289-94. doi: 10.2147/dddt.s8133.

2-Phenylamino-6-oxo-9-(4-hydroxybutyl)purine (HBPG) is a thymidine kinase inhibitor that prevents encephalitic death in mice caused by herpes simplex virus (HSV) types 1 and 2, although its potency is somewhat less than that of acyclovir (ACV). The present study was undertaken...

Orthopoxvirus inhibitors that are active in animal models: an update from 2008 to 2012.

Future virology

Smee DF.
PMID: 24563659
Future Virol. 2013 Sep;8(9):891-901. doi: 10.2217/fvl.13.76.

Antiviral agents are being sought as countermeasures for the potential deliberate release of smallpox (variola) and monkeypox viruses, for the treatment of naturally acquired monkeypox virus infections, and as therapy for complications due to smallpox (live-attenuated vaccinia virus) vaccination...

La Revue du praticien

Agut H, Burrel S, Bonnafous P, Boutolleau D.
PMID: 30512372
Rev Prat. 2016 Nov;66(9):1007-1014.

Research for novel antivirals: where are we going? Antiviral drugs have become a critical component of anti-infective treatments, as illustrated by the development of antiretrovirals and antiviral drugs directed against hepatitis B and C viruses. Several other molecules are...

Letermovir for the prevention of cytomegalovirus infection and disease in transplant recipients: an evidence-based review.

Infection and drug resistance

El Helou G, Razonable RR.
PMID: 31239725
Infect Drug Resist. 2019 Jun 04;12:1481-1491. doi: 10.2147/IDR.S180908. eCollection 2019.

Cytomegalovirus (CMV) is a leading opportunistic infection in immune compromised patients, including allogeneic hematopoietic stem cell (HSCT) or solid organ transplant (SOT) recipients, where primary infection or reactivation is associated with increased morbidity and mortality. Antiviral drugs are the...

Successful Treatment of Adenovirus Infection with Brincidofovir in an Immunocompromised Patient after Hematological Stem Cell Transplantation.

Case reports in infectious diseases

Van Genechten T, van Heerden J, Bauters T, Dhooge C.
PMID: 31970003
Case Rep Infect Dis. 2020 Jan 07;2020:5981289. doi: 10.1155/2020/5981289. eCollection 2020.

Immunocompromised patients, including hematopoietic stem cell transplantation (HSCT), HIV, and malnourished patients, are at increased risk for viral infections with high incidences of morbidity and mortality. In HSCT patients, the infection risk is increased until immune reconstitution is re-established....

Showing 1 to 12 of 146 entries