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Showing 1 to 12 of 50 entries
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Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine.

European journal of clinical pharmacology

Jhang KM, Huang JY, Nfor ON, Tung YC, Ku WY, Lee CT, Liaw YP.
PMID: 28567501
Eur J Clin Pharmacol. 2017 Jul;73(7):917. doi: 10.1007/s00228-017-2268-5.

No abstract available.

DUPLICATE: Cinnarizine: A Promising Agent for Migraine Prevention You May Never Get the Chance to Use.

Pediatric neurology

Disabella MT.
PMID: 25920550
Pediatr Neurol. 2014 Aug 07; doi: 10.1016/j.pediatrneurol.2014.08.001. Epub 2014 Aug 07.

The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.pediatrneurol.2014.07.002. The duplicate article has therefore been removed. The full Elsevier Policy on Article Removal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Time-course of effects of oral cinnarizine and hyoscine on task performance.

Journal of psychopharmacology (Oxford, England)

Golding JF, Strong R, Pethybridge RJ.
PMID: 22282908
J Psychopharmacol. 1989 Jan;3(4):187-97. doi: 10.1177/026988118900300401.

Investigations into antimotion sickness drugs fall into two main categories: efficacy ('benefits') and side-effects ('costs'). This study was of the second type. Oral cinnarizine (30 mg: normal dose; and 75 mg: 2.5 x normal dose) and placebo, were investigated...

Formulation and evaluation of mouth dissolving tablets of cinnarizine.

Indian journal of pharmaceutical sciences

Patel BP, Patel JK, Rajput GC, Thakor RS.
PMID: 21218071
Indian J Pharm Sci. 2010 Jul;72(4):522-5. doi: 10.4103/0250-474X.73930.

The purpose of this research was to develop mouth dissolve tablets of cinnarizine by effervescent, superdisintegrant addition and sublimation methods. All the three formulations were evaluated for disintegration time, hardness and friability, among these superdisintegrant addition method showed lowest...

A Case of Orbital Myositis Presenting With Dizziness.

Open access Macedonian journal of medical sciences

Aquilina N, Bugeja V, Zahra C.
PMID: 30087737
Open Access Maced J Med Sci. 2018 Jul 13;6(7):1278-1281. doi: 10.3889/oamjms.2018.192. eCollection 2018 Jul 20.

BACKGROUND: Orbital myositis is an idiopathic, inflammatory, non-infectious condition, typically confined to more than one extraocular muscle and usually targeting young females in their third decade.CASE REPORT: We describe a case of orbital myositis uncommonly afflicting an adult male....

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers.

Pharmaceutics

Blaabjerg LI, Grohganz H, Lindenberg E, Löbmann K, Müllertz A, Rades T.
PMID: 30241425
Pharmaceutics. 2018 Sep 21;10(4). doi: 10.3390/pharmaceutics10040164.

The increasing number of poorly water-soluble drug candidates in pharmaceutical development is a major challenge. Enabling techniques such as amorphization of the crystalline drug can result in supersaturation with respect to the thermodynamically most stable form of the drug,...

The role interplay between mesoporous silica pore volume and surface area and their effect on drug loading capacity.

International journal of pharmaceutics: X

Bavnhøj CG, Knopp MM, Madsen CM, Löbmann K.
PMID: 31517273
Int J Pharm X. 2019 Feb 22;1:100008. doi: 10.1016/j.ijpx.2019.100008. eCollection 2019 Dec.

In this study, the influence of the mesoporous silica (MS) textural properties (surface area, pore diameter, and pore volume) on drug loading capacity (monomolecular loading capacity and pore filling capacity) was investigated theoretically and experimentally using a thermoanalytical method....

Versatile TLC-Densitometric Methods for the Synchronous Estimation of Cinnarizine and Acefylline Heptaminol in The Presence of Potential Impurity and Their Reported Degradation Products.

Journal of chromatographic science

El-Houssini OM, Mohammad MA.
PMID: 34875682
J Chromatogr Sci. 2021 Dec 08; doi: 10.1093/chromsci/bmab129. Epub 2021 Dec 08.

From evolution, thin-layer chromatography (TLC) attracts attention as a versatile technique for efficient separation and identification of many drug substances and chemicals. Owing to its simplicity and other outstanding advantages, TLC is extensively used by chromatographers in quantification and...

Combined Self-Nanoemulsifying and Solid Dispersion Systems Showed Enhanced Cinnarizine Release in Hypochlorhydria/Achlorhydria Dissolution Model.

Pharmaceutics

Shahba AA, Tashish AY, Alanazi FK, Kazi M.
PMID: 33924928
Pharmaceutics. 2021 Apr 28;13(5). doi: 10.3390/pharmaceutics13050627.

The study aims to design a novel combination of drug-free solid self-nanoemulsifying drug delivery systems (S-SNEDDS) + solid dispersion (SD) to enhance cinnarizine (CN) dissolution at high pH environment caused by hypochlorhydria/achlorhydria. Drug-loaded and drug-free liquid SNEDDS were solidified...

Increasing the Robustness of Biopharmaceutical Precipitation Assays - Part I: Derivative UV Spectrophotometric Method Development for in-line Measurements.

Journal of pharmaceutical sciences

Lehmann A, Krollik K, Beran K, Hirtreiter C, Kubas H, Wagner C.
PMID: 34464648
J Pharm Sci. 2022 Jan;111(1):146-154. doi: 10.1016/j.xphs.2021.08.025. Epub 2021 Aug 28.

In vitro precipitation assays are often applied to support drug and formulation development. Current methods applied to quantify the amount of dissolved drug, in particular (U)HPLC, require time-consuming sample preparation. Furthermore, small precipitates formed during the nucleation phase may...

Cinnarizine/dimenhydrinate for vertigo.

Australian prescriber

[No authors listed]
PMID: 33911336
Aust Prescr. 2021 Apr;44(2):62-63. doi: 10.18773/austprescr.2021.009. Epub 2021 Mar 04.

No abstract available.

Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug.

Asian journal of pharmaceutical sciences

Patel M, Hirlekar R.
PMID: 32104443
Asian J Pharm Sci. 2019 Jan;14(1):104-115. doi: 10.1016/j.ajps.2018.02.007. Epub 2018 Mar 13.

The purpose of the present study was to investigate the interaction of Cinnarizine (CIN) with Hydroxypropyl-β-Cyclodextrin (HPβCD) in the presence of Hydroxy Acids (HA). Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading...

Showing 1 to 12 of 50 entries