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A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library.

Frontiers in microbiology

Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y.
PMID: 27242757
Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016.

Although currently recommended antibiotics for Lyme disease such as doxycycline or amoxicillin cure the majority of the patients, about 10-20% of patients treated for Lyme disease may experience lingering symptoms including fatigue, pain, or joint and muscle aches. Under...

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Feng J, Shi W, Zhang S, et al. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016;7:743doi: 10.3389/fmicb.2016.00743.
Feng, J., Shi, W., Zhang, S., Sullivan, D., Auwaerter, P. G., & Zhang, Y. (2016). A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Frontiers in microbiology, 7743. https://doi.org/10.3389/fmicb.2016.00743
Feng, Jie, et al. "A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library." Frontiers in microbiology vol. 7 (2016): 743. doi: https://doi.org/10.3389/fmicb.2016.00743
Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y. A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library. Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016. PMID: 27242757; PMCID: PMC4876775.
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Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy.

Biomedical optics express

Rzeczycki P, Yoon GS, Keswani RK, Sud S, Stringer KA, Rosania GR.
PMID: 28270989
Biomed Opt Express. 2017 Jan 13;8(2):860-872. doi: 10.1364/BOE.8.000860. eCollection 2017 Feb 01.

Following prolonged administration, certain orally bioavailable but poorly soluble small molecule drugs are prone to precipitate out and form crystal-like drug inclusions (CLDIs) within the cells of living organisms. In this research, we present a quantitative multi-parameter imaging platform...

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Rzeczycki P, Yoon GS, Keswani RK, et al. Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy. Biomed Opt Express. 2017;8(2):860-872doi: 10.1364/BOE.8.000860.
Rzeczycki, P., Yoon, G. S., Keswani, R. K., Sud, S., Stringer, K. A., & Rosania, G. R. (2017). Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy. Biomedical optics express, 8(2), 860-872. https://doi.org/10.1364/BOE.8.000860
Rzeczycki, Phillip, et al. "Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy." Biomedical optics express vol. 8,2 (2017): 860-872. doi: https://doi.org/10.1364/BOE.8.000860
Rzeczycki P, Yoon GS, Keswani RK, Sud S, Stringer KA, Rosania GR. Detecting ordered small molecule drug aggregates in live macrophages: a multi-parameter microscope image data acquisition and analysis strategy. Biomed Opt Express. 2017 Jan 13;8(2):860-872. doi: 10.1364/BOE.8.000860. eCollection 2017 Feb 01. PMID: 28270989; PMCID: PMC5330574.
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Drug potentiation of macrophage function.

Infection and immunity

Cline MJ.
PMID: 16557883
Infect Immun. 1970 Nov;2(5):601-5. doi: 10.1128/iai.2.5.601-605.1970.

The mechanism by which macrophages kill facultative intracellular parasites is not known. A test system is described utilizing human macrophages derived from blood monocytes and the opportunistic pathogen Listeria monocytogenes. In this system, bacterial killing was impaired under hypoxic...

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Cline MJ. Drug potentiation of macrophage function. Infect Immun. 1970;2(5):601-5doi: 10.1128/iai.2.5.601-605.1970.
Cline, M. J. (1970). Drug potentiation of macrophage function. Infection and immunity, 2(5), 601-5. https://doi.org/10.1128/iai.2.5.601-605.1970
Cline, M J. "Drug potentiation of macrophage function." Infection and immunity vol. 2,5 (1970): 601-5. doi: https://doi.org/10.1128/iai.2.5.601-605.1970
Cline MJ. Drug potentiation of macrophage function. Infect Immun. 1970 Nov;2(5):601-5. doi: 10.1128/iai.2.5.601-605.1970. PMID: 16557883; PMCID: PMC416056.
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Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice.

International journal of oncology

Vanrensburg C, Durandt C, Garlinski P, Osullivan J.
PMID: 21573467
Int J Oncol. 1993 Nov;3(5):1011-3. doi: 10.3892/ijo.3.5.1011.

The riminophenazine agents clofazimine and its analogue B669 displayed anti-tumor activity at 30 mg/kg/day in benzo[a]pyrene (BP) induced sarcomas of mice as well as dimethylbenz-anthracene (DMBA)-induced rat mammary tumors. No hematological toxicity of these drugs at doses up to...

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Vanrensburg C, Durandt C, Garlinski P, et al. Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice. Int J Oncol. 1993;3(5):1011-3doi: 10.3892/ijo.3.5.1011.
Vanrensburg, C., Durandt, C., Garlinski, P., & Osullivan, J. (1993). Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice. International journal of oncology, 3(5), 1011-3. https://doi.org/10.3892/ijo.3.5.1011
Vanrensburg, C, et al. "Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice." International journal of oncology vol. 3,5 (1993): 1011-3. doi: https://doi.org/10.3892/ijo.3.5.1011
Vanrensburg C, Durandt C, Garlinski P, Osullivan J. Evaluation of the antineoplastic activities of the riminophenazine agents clofazimine and b669 in tumor-bearing rats and mice. Int J Oncol. 1993 Nov;3(5):1011-3. doi: 10.3892/ijo.3.5.1011. PMID: 21573467.
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Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in .

Data in brief

Ismail N, Omar SV, Ismail NA, Peters RPH.
PMID: 30306102
Data Brief. 2018 Sep 24;20:1975-1983. doi: 10.1016/j.dib.2018.09.057. eCollection 2018 Oct.

A comprehensive literature search was conducted to obtain previously published resistance associated mutations for bedaquiline, clofazimine and linezolid for

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Ismail N, Omar SV, Ismail NA, et al. Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in . Data Brief. 2018;20:1975-1983doi: 10.1016/j.dib.2018.09.057.
Ismail, N., Omar, S. V., Ismail, N. A., & Peters, R. P. H. (2018). Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in . Data in brief, 201975-1983. https://doi.org/10.1016/j.dib.2018.09.057
Ismail, N, et al. "Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in ." Data in brief vol. 20 (2018): 1975-1983. doi: https://doi.org/10.1016/j.dib.2018.09.057
Ismail N, Omar SV, Ismail NA, Peters RPH. Collated data of mutation frequencies and associated genetic variants of bedaquiline, clofazimine and linezolid resistance in . Data Brief. 2018 Sep 24;20:1975-1983. doi: 10.1016/j.dib.2018.09.057. eCollection 2018 Oct. PMID: 30306102; PMCID: PMC6172430.
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Extensively Drug-resistant Tuberculosis of the Lumbar Spine in a Six-year-old Child: A Case Report.

Journal of orthopaedic case reports

Shah SS, Goregaonkar AA, Goregaonkar AB.
PMID: 28819600
J Orthop Case Rep. 2017 Mar-Apr;7(2):40-43. doi: 10.13107/jocr.2250-0685.742.

INTRODUCTION: The emergence of extensively drug-resistant tuberculosis (XDR-TB) is a challenging paradigm shift faced by the TB control programs worldwide today. The treatment is further compounded with unique management difficulties faced in pediatric patients. Treatment of XDR-TB requires prolonged...

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Shah SS, Goregaonkar AA, Goregaonkar AB. Extensively Drug-resistant Tuberculosis of the Lumbar Spine in a Six-year-old Child: A Case Report. J Orthop Case Rep. 2017;7(2):40-43doi: 10.13107/jocr.2250-0685.742.
Shah, S. S., Goregaonkar, A. A., & Goregaonkar, A. B. (2017). Extensively Drug-resistant Tuberculosis of the Lumbar Spine in a Six-year-old Child: A Case Report. Journal of orthopaedic case reports, 7(2), 40-43. https://doi.org/10.13107/jocr.2250-0685.742
Shah, Siddharth Sanjay, et al. "Extensively Drug-resistant Tuberculosis of the Lumbar Spine in a Six-year-old Child: A Case Report." Journal of orthopaedic case reports vol. 7,2 (2017): 40-43. doi: https://doi.org/10.13107/jocr.2250-0685.742
Shah SS, Goregaonkar AA, Goregaonkar AB. Extensively Drug-resistant Tuberculosis of the Lumbar Spine in a Six-year-old Child: A Case Report. J Orthop Case Rep. 2017 Mar-Apr;7(2):40-43. doi: 10.13107/jocr.2250-0685.742. PMID: 28819600; PMCID: PMC5553834.
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Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche.

Open forum infectious diseases

McGuffin SA, Pottinger PS, Harnisch JP.
PMID: 30202770
Open Forum Infect Dis. 2017 Jul 20;4(3):ofx147. doi: 10.1093/ofid/ofx147. eCollection 2017.

Infection secondary to rapidly growing mycobacteria (RGM) is associated with significant morbidity and mortality, especially in individuals with underlying structural lung disease or immune compromise. Such infections, particularly those caused by the

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McGuffin SA, Pottinger PS, Harnisch JP. Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche. Open Forum Infect Dis. 2017;4(3):ofx147doi: 10.1093/ofid/ofx147.
McGuffin, S. A., Pottinger, P. S., & Harnisch, J. P. (2017). Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche. Open forum infectious diseases, 4(3), ofx147. https://doi.org/10.1093/ofid/ofx147
McGuffin, Sarah A, et al. "Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche." Open forum infectious diseases vol. 4,3 (2017): ofx147. doi: https://doi.org/10.1093/ofid/ofx147
McGuffin SA, Pottinger PS, Harnisch JP. Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche. Open Forum Infect Dis. 2017 Jul 20;4(3):ofx147. doi: 10.1093/ofid/ofx147. eCollection 2017. PMID: 30202770; PMCID: PMC6124512.
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Melkersson-rosenthal Syndrome Responding to Clofazimine Therapy.

Indian journal of dermatology, venereology and leprology

Pavithran K.
PMID: 28128188
Indian J Dermatol Venereol Leprol. 1989 Jul-Aug;55(4):262-264.

Two- patients had Melkersson-Rosenthal' syndrome. One of them had all the 3 components of the syndrome-facial paralysis, plicated tongue and macrocheilia, while the other had only 2 components-macrocheilia and plicated tongue. Oral antihistamine therapy for 3 weeks was ineffective...

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Pavithran K. Melkersson-rosenthal Syndrome Responding to Clofazimine Therapy. Indian J Dermatol Venereol Leprol. 1989;55(4):262-264
Pavithran, K. (1989). Melkersson-rosenthal Syndrome Responding to Clofazimine Therapy. Indian journal of dermatology, venereology and leprology, 55(4), 262-264.
Pavithran, K. "Melkersson-rosenthal Syndrome Responding to Clofazimine Therapy." Indian journal of dermatology, venereology and leprology vol. 55,4 (1989): 262-264.
Pavithran K. Melkersson-rosenthal Syndrome Responding to Clofazimine Therapy. Indian J Dermatol Venereol Leprol. 1989 Jul-Aug;55(4):262-264. PMID: 28128188.
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Clofazimine.

Indian journal of dermatology, venereology and leprology

Kumar B, Mandal SK.
PMID: 20921771
Indian J Dermatol Venereol Leprol. 1998 Sep-Oct;64(5):211-9.

No abstract available.

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Kumar B, Mandal SK. Clofazimine. Indian J Dermatol Venereol Leprol. 1998;64(5):211-9
Kumar, B., & Mandal, S. K. (1998). Clofazimine. Indian journal of dermatology, venereology and leprology, 64(5), 211-9.
Kumar, B, and Mandal, S K. "Clofazimine." Indian journal of dermatology, venereology and leprology vol. 64,5 (1998): 211-9.
Kumar B, Mandal SK. Clofazimine. Indian J Dermatol Venereol Leprol. 1998 Sep-Oct;64(5):211-9. PMID: 20921771.
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Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India.

Journal of clinical tuberculosis and other mycobacterial diseases

Tornheim JA, Intini E, Gupta A, Udwadia ZF.
PMID: 32775702
J Clin Tuberc Other Mycobact Dis. 2020 Jul 24;20:100175. doi: 10.1016/j.jctube.2020.100175. eCollection 2020 Aug.

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is an increasing problem worldwide, and 24% occurs in India. Linezolid is associated with improved MDR-TB treatment outcomes but causes significant side-effects and drug susceptibility testing (DST) is rarely available. This study assessed whether clinical...

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Tornheim JA, Intini E, Gupta A, et al. Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India. J Clin Tuberc Other Mycobact Dis. 2020;20:100175doi: 10.1016/j.jctube.2020.100175.
Tornheim, J. A., Intini, E., Gupta, A., & Udwadia, Z. F. (2020). Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India. Journal of clinical tuberculosis and other mycobacterial diseases, 20100175. https://doi.org/10.1016/j.jctube.2020.100175
Tornheim, J A, et al. "Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India." Journal of clinical tuberculosis and other mycobacterial diseases vol. 20 (2020): 100175. doi: https://doi.org/10.1016/j.jctube.2020.100175
Tornheim JA, Intini E, Gupta A, Udwadia ZF. Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India. J Clin Tuberc Other Mycobact Dis. 2020 Jul 24;20:100175. doi: 10.1016/j.jctube.2020.100175. eCollection 2020 Aug. PMID: 32775702; PMCID: PMC7398971.
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A new .

Heliyon

Maladan Y, Krismawati H, Hutapea HML, Oktavian A, Fatimah R, Widodo.
PMID: 31016254
Heliyon. 2019 Mar 07;5(3):e01279. doi: 10.1016/j.heliyon.2019.e01279. eCollection 2019 Mar.

Indonesia had the third highest number of new leprosy cases worldwide in 2017. This disease is still prevalent in Papua province, where the number of new cases in 2014 (3.0 cases per 10,000 people) is considered highly endemic and...

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Maladan Y, Krismawati H, Hutapea HML, et al. A new . Heliyon. 2019;5(3):e01279doi: 10.1016/j.heliyon.2019.e01279.
Maladan, Y., Krismawati, H., Hutapea, H. M. L., Oktavian, A., Fatimah, R., & Widodo. (2019). A new . Heliyon, 5(3), e01279. https://doi.org/10.1016/j.heliyon.2019.e01279
Maladan, Yustinus, et al. "A new ." Heliyon vol. 5,3 (2019): e01279. doi: https://doi.org/10.1016/j.heliyon.2019.e01279
Maladan Y, Krismawati H, Hutapea HML, Oktavian A, Fatimah R, Widodo. A new . Heliyon. 2019 Mar 07;5(3):e01279. doi: 10.1016/j.heliyon.2019.e01279. eCollection 2019 Mar. PMID: 31016254; PMCID: PMC6475649.
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Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment.

International journal of women's dermatology

Leung N, Oliveira M, Selim MA, McKinley-Grant L, Lesesky E.
PMID: 30627620
Int J Womens Dermatol. 2018 Sep 27;4(4):216-222. doi: 10.1016/j.ijwd.2018.08.003. eCollection 2018 Dec.

OBJECTIVE: Erythema dyschromicum perstans (EDP) can be difficult to diagnose and treat; therefore, we reviewed the literature to assess whether histology can be used to differentiate lichen planus pigmentosus (LPP) from EDP and determine which treatments are the most...

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Leung N, Oliveira M, Selim MA, et al. Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment. Int J Womens Dermatol. 2018;4(4):216-222doi: 10.1016/j.ijwd.2018.08.003.
Leung, N., Oliveira, M., Selim, M. A., McKinley-Grant, L., & Lesesky, E. (2018). Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment. International journal of women's dermatology, 4(4), 216-222. https://doi.org/10.1016/j.ijwd.2018.08.003
Leung, N, et al. "Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment." International journal of women's dermatology vol. 4,4 (2018): 216-222. doi: https://doi.org/10.1016/j.ijwd.2018.08.003
Leung N, Oliveira M, Selim MA, McKinley-Grant L, Lesesky E. Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment. Int J Womens Dermatol. 2018 Sep 27;4(4):216-222. doi: 10.1016/j.ijwd.2018.08.003. eCollection 2018 Dec. PMID: 30627620; PMCID: PMC6322153.
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Showing 1 to 12 of 161 entries