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Effectiveness of ultra-rapid dose titration of clozapine for treatment-resistant bipolar mania: case series.

Therapeutic advances in psychopharmacology

Aksoy Poyraz C, Turan Ş, Demirel ÖF, Usta Sağlam NG, Yıldız N, Duran A.
PMID: 26301080
Ther Adv Psychopharmacol. 2015 Aug;5(4):237-42. doi: 10.1177/2045125315584871.

Treatment of severe and refractory manic episodes in hospital settings can occasionally be very difficult. In particular, severely excited patients showing aggressive, hostile, impulsive behaviours frequently require physical restraint and seclusion, high doses of antipsychotics and benzodiazepines, and sometimes,...

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Aksoy Poyraz C, Turan Ş, Demirel ÖF, et al. Effectiveness of ultra-rapid dose titration of clozapine for treatment-resistant bipolar mania: case series. Ther Adv Psychopharmacol. 2015;5(4):237-42doi: 10.1177/2045125315584871.
Aksoy Poyraz, C., Turan, �. �., Demirel, �. �. F., Usta Sağlam, N. G., Yıldız, N., & Duran, A. (2015). Effectiveness of ultra-rapid dose titration of clozapine for treatment-resistant bipolar mania: case series. Therapeutic advances in psychopharmacology, 5(4), 237-42. https://doi.org/10.1177/2045125315584871
Aksoy Poyraz, Cana, et al. "Effectiveness of ultra-rapid dose titration of clozapine for treatment-resistant bipolar mania: case series." Therapeutic advances in psychopharmacology vol. 5,4 (2015): 237-42. doi: https://doi.org/10.1177/2045125315584871
Aksoy Poyraz C, Turan Ş, Demirel ÖF, Usta Sağlam NG, Yıldız N, Duran A. Effectiveness of ultra-rapid dose titration of clozapine for treatment-resistant bipolar mania: case series. Ther Adv Psychopharmacol. 2015 Aug;5(4):237-42. doi: 10.1177/2045125315584871. PMID: 26301080; PMCID: PMC4535045.
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The significance of the expression of Fos protein in the brain for the classification of antipsychotics.

Acta neuropsychiatrica

Korf J, Sebens JB.
PMID: 26972456
Acta Neuropsychiatr. 1997 Dec;9(4):143-50. doi: 10.1017/S0924270800036711.

Samenvatting In de afgelopen zes jaar is veel onderzoek verficht naar de effecten van antipsychotica op de regionale c-fos-expressie in de hersenen. Deze benadering biedt in een dierexperimentele proefopzet de mogelijkheid op cellulair niveau de effecten van psychofarmaca te...

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Korf J, Sebens JB. The significance of the expression of Fos protein in the brain for the classification of antipsychotics. Acta Neuropsychiatr. 1997;9(4):143-50doi: 10.1017/S0924270800036711.
Korf, J., & Sebens, J. B. (1997). The significance of the expression of Fos protein in the brain for the classification of antipsychotics. Acta neuropsychiatrica, 9(4), 143-50. https://doi.org/10.1017/S0924270800036711
Korf, J, and Sebens, J B. "The significance of the expression of Fos protein in the brain for the classification of antipsychotics." Acta neuropsychiatrica vol. 9,4 (1997): 143-50. doi: https://doi.org/10.1017/S0924270800036711
Korf J, Sebens JB. The significance of the expression of Fos protein in the brain for the classification of antipsychotics. Acta Neuropsychiatr. 1997 Dec;9(4):143-50. doi: 10.1017/S0924270800036711. PMID: 26972456.
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Low-dose Clozapine-induced Seizure: A Case Report.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Bolu A, Akarsu S, Pan E, Aydemir E, Oznur T.
PMID: 28449570
Clin Psychopharmacol Neurosci. 2017 May 31;15(2):190-193. doi: 10.9758/cpn.2017.15.2.190.

Seizures are believed to be a dose-dependent side effect of clozapine. In this case report, we describe a patient who had tonic-clonic seizures after using a low dose clozapine who did not have any seizure risk. The 29-year-old male...

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Bolu A, Akarsu S, Pan E, et al. Low-dose Clozapine-induced Seizure: A Case Report. Clin Psychopharmacol Neurosci. 2017;15(2):190-193doi: 10.9758/cpn.2017.15.2.190.
Bolu, A., Akarsu, S., Pan, E., Aydemir, E., & Oznur, T. (2017). Low-dose Clozapine-induced Seizure: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 15(2), 190-193. https://doi.org/10.9758/cpn.2017.15.2.190
Bolu, Abdullah, et al. "Low-dose Clozapine-induced Seizure: A Case Report." Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology vol. 15,2 (2017): 190-193. doi: https://doi.org/10.9758/cpn.2017.15.2.190
Bolu A, Akarsu S, Pan E, Aydemir E, Oznur T. Low-dose Clozapine-induced Seizure: A Case Report. Clin Psychopharmacol Neurosci. 2017 May 31;15(2):190-193. doi: 10.9758/cpn.2017.15.2.190. PMID: 28449570; PMCID: PMC5426497.
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Serum prolactin levels and sexual dysfunctions in antipsychotic medication, such as risperidone: a review.

Acta neuropsychiatrica

Knegtering H, Lambers PA, Prakken G, Ten Brink C.
PMID: 26976681
Acta Neuropsychiatr. 2000 Mar;12(1):19-26. doi: 10.1017/S092427080003578X.

Classical antipsychotic drugs increase the level of serum prolactin. The atypical antipsychotic clozapine barely increases prolactin levels. An open naturalistic study in the University Hospital of Groningen suggests that treatment with risperidone in comparison to classical antipsychotics seems to...

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Knegtering H, Lambers PA, Prakken G, et al. Serum prolactin levels and sexual dysfunctions in antipsychotic medication, such as risperidone: a review. Acta Neuropsychiatr. 2000;12(1):19-26doi: 10.1017/S092427080003578X.
Knegtering, H., Lambers, P. A., Prakken, G., & Ten Brink, C. (2000). Serum prolactin levels and sexual dysfunctions in antipsychotic medication, such as risperidone: a review. Acta neuropsychiatrica, 12(1), 19-26. https://doi.org/10.1017/S092427080003578X
Knegtering, H, et al. "Serum prolactin levels and sexual dysfunctions in antipsychotic medication, such as risperidone: a review." Acta neuropsychiatrica vol. 12,1 (2000): 19-26. doi: https://doi.org/10.1017/S092427080003578X
Knegtering H, Lambers PA, Prakken G, Ten Brink C. Serum prolactin levels and sexual dysfunctions in antipsychotic medication, such as risperidone: a review. Acta Neuropsychiatr. 2000 Mar;12(1):19-26. doi: 10.1017/S092427080003578X. PMID: 26976681.
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»Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia.

Journal of medical biochemistry

Marić NP, Nikolić SP, Buzadžić I, Jovičić M, Andrić S, Mihaljević M, Pavlović Z.
PMID: 28356835
J Med Biochem. 2015 Apr;34(2):223-227. doi: 10.2478/jomb-2014-0041. Epub 2015 Mar 03.

The introduction of antipsychotic medication in the 1950s forever changed the outlook on the treatment of schizophrenia, although there is still a large proportion of patients who do not reach functional recovery. At least 30% of patients do not...

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Marić NP, Nikolić SP, Buzadžić I, et al. »Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia. J Med Biochem. 2015;34(2):223-227doi: 10.2478/jomb-2014-0041.
Marić, N. P., Nikolić, S. P., Buzadžić, I., Jovičić, M., Andrić, S., Mihaljević, M., & Pavlović, Z. (2015). »Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia. Journal of medical biochemistry, 34(2), 223-227. https://doi.org/10.2478/jomb-2014-0041
Marić, Nadja P, et al. "»Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia." Journal of medical biochemistry vol. 34,2 (2015): 223-227. doi: https://doi.org/10.2478/jomb-2014-0041
Marić NP, Nikolić SP, Buzadžić I, Jovičić M, Andrić S, Mihaljević M, Pavlović Z. »Treatment Resistance« Enigma Resolved by Pharmacogenomics - A Case Study of Clozapine Therapy in Schizophrenia. J Med Biochem. 2015 Apr;34(2):223-227. doi: 10.2478/jomb-2014-0041. Epub 2015 Mar 03. PMID: 28356835; PMCID: PMC4922322.
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Clozapine-Induced Myocarditis: A Case Report of an Adolescent Boy with Intellectual Disability.

Case reports in psychiatry

Aboueid L, Toteja N.
PMID: 26266072
Case Rep Psychiatry. 2015;2015:482375. doi: 10.1155/2015/482375. Epub 2015 Jul 22.

Background. Although known for its efficacy in treatment-resistant schizophrenia, the usage of clozapine has been limited due to concerns over potential adverse effects. Myocarditis, one potential fatal complication, can develop at any point during treatment but has been most...

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Aboueid L, Toteja N. Clozapine-Induced Myocarditis: A Case Report of an Adolescent Boy with Intellectual Disability. Case Rep Psychiatry. 2015;2015:482375doi: 10.1155/2015/482375.
Aboueid, L., & Toteja, N. (2015). Clozapine-Induced Myocarditis: A Case Report of an Adolescent Boy with Intellectual Disability. Case reports in psychiatry, 2015482375. https://doi.org/10.1155/2015/482375
Aboueid, Lila, and Toteja, Nitin. "Clozapine-Induced Myocarditis: A Case Report of an Adolescent Boy with Intellectual Disability." Case reports in psychiatry vol. 2015 (2015): 482375. doi: https://doi.org/10.1155/2015/482375
Aboueid L, Toteja N. Clozapine-Induced Myocarditis: A Case Report of an Adolescent Boy with Intellectual Disability. Case Rep Psychiatry. 2015;2015:482375. doi: 10.1155/2015/482375. Epub 2015 Jul 22. PMID: 26266072; PMCID: PMC4525764.
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Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit.

Therapeutic advances in psychopharmacology

Gee SH, Taylor DM, Shergill SS, Flanagan R, MacCabe JH.
PMID: 28255437
Ther Adv Psychopharmacol. 2017 Feb;7(2):79-83. doi: 10.1177/2045125316677027. Epub 2016 Dec 02.

BACKGROUND: Tobacco smoke is known to affect plasma levels of some drugs, including the antipsychotic clozapine. The effects of suddenly stopping smoking on patients who take clozapine can be severe, as plasma concentrations are expected to rapidly rise, potentially...

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Gee SH, Taylor DM, Shergill SS, et al. Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit. Ther Adv Psychopharmacol. 2016;7(2):79-83doi: 10.1177/2045125316677027.
Gee, S. H., Taylor, D. M., Shergill, S. S., Flanagan, R., & MacCabe, J. H. (2017). Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit. Therapeutic advances in psychopharmacology, 7(2), 79-83. https://doi.org/10.1177/2045125316677027
Gee, Siobhan H, et al. "Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit." Therapeutic advances in psychopharmacology vol. 7,2 (2017): 79-83. doi: https://doi.org/10.1177/2045125316677027
Gee SH, Taylor DM, Shergill SS, Flanagan R, MacCabe JH. Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit. Ther Adv Psychopharmacol. 2017 Feb;7(2):79-83. doi: 10.1177/2045125316677027. Epub 2016 Dec 02. PMID: 28255437; PMCID: PMC5315231.
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Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response.

Case reports in psychiatry

Aboueid L, McCarthy RH.
PMID: 27433365
Case Rep Psychiatry. 2016;2016:6123913. doi: 10.1155/2016/6123913. Epub 2016 Jun 28.

Clozapine has been consistently shown to be superior to other antipsychotics in the treatment of psychosis. However, clozapine usage has been limited due to required routine blood monitoring and the potential for life threatening side effects. We report a...

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Aboueid L, McCarthy RH. Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response. Case Rep Psychiatry. 2016;2016:6123913doi: 10.1155/2016/6123913.
Aboueid, L., & McCarthy, R. H. (2016). Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response. Case reports in psychiatry, 20166123913. https://doi.org/10.1155/2016/6123913
Aboueid, Lila, and McCarthy, Richard H. "Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response." Case reports in psychiatry vol. 2016 (2016): 6123913. doi: https://doi.org/10.1155/2016/6123913
Aboueid L, McCarthy RH. Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response. Case Rep Psychiatry. 2016;2016:6123913. doi: 10.1155/2016/6123913. Epub 2016 Jun 28. PMID: 27433365; PMCID: PMC4940529.
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Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register.

NPJ schizophrenia

Cardinal RN, Savulich G, Mann LM, Fernández-Egea E.
PMID: 27336041
NPJ Schizophr. 2015 Oct 21;1:15035. doi: 10.1038/npjschz.2015.35. eCollection 2015.

BACKGROUND: The impact of psychotropic drug choice upon admissions for schizophrenia is not well understood.AIMS: To examine the association between antipsychotic/antidepressant use and time in hospital for patients with schizophrenia.METHODS: We conducted an observational study, using 8 years' admission...

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Cardinal RN, Savulich G, Mann LM, et al. Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register. NPJ Schizophr. 2015;1:15035doi: 10.1038/npjschz.2015.35.
Cardinal, R. N., Savulich, G., Mann, L. M., & Fernández-Egea, E. (2015). Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register. NPJ schizophrenia, 115035. https://doi.org/10.1038/npjschz.2015.35
Cardinal, Rudolf N, et al. "Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register." NPJ schizophrenia vol. 1 (2015): 15035. doi: https://doi.org/10.1038/npjschz.2015.35
Cardinal RN, Savulich G, Mann LM, Fernández-Egea E. Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register. NPJ Schizophr. 2015 Oct 21;1:15035. doi: 10.1038/npjschz.2015.35. eCollection 2015. PMID: 27336041; PMCID: PMC4849458.
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The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects.

NPJ schizophrenia

Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G.
PMID: 27336047
NPJ Schizophr. 2015 Nov 11;1:15046. doi: 10.1038/npjschz.2015.46. eCollection 2015.

BACKGROUND: Metabolic syndrome may be related to folate's pharmacogenetically regulated metabolism and atypical antipsychotic (AAP) exposure.AIMS: We examined folate supplementation on metabolic measures, endothelial functioning (Reactive Hyperemia Index (RHI)), and global methylation in AAP-treated schizophrenia subjects meeting NCEP-ATP-III-a metabolic...

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Ellingrod VL, Grove TB, Burghardt KJ, et al. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ Schizophr. 2015;1:15046doi: 10.1038/npjschz.2015.46.
Ellingrod, V. L., Grove, T. B., Burghardt, K. J., Taylor, S. F., & Dalack, G. (2015). The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ schizophrenia, 115046. https://doi.org/10.1038/npjschz.2015.46
Ellingrod, Vicki L, et al. "The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects." NPJ schizophrenia vol. 1 (2015): 15046. doi: https://doi.org/10.1038/npjschz.2015.46
Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. NPJ Schizophr. 2015 Nov 11;1:15046. doi: 10.1038/npjschz.2015.46. eCollection 2015. PMID: 27336047; PMCID: PMC4849464.
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Metabolic Disturbances, Side Effect Profile and Effectiveness of Clozapine in Adolescents.

Indian journal of psychological medicine

Grover S, Hazari N, Chakrabarti S, Avasthi A.
PMID: 27335518
Indian J Psychol Med. 2016 May-Jun;38(3):224-33. doi: 10.4103/0253-7176.183091.

INTRODUCTION: Data on effect of clozapine on metabolic syndrome in adolescent patients with psychosis are limited. This study aimed to evaluate the prevalence and incidence of metabolic syndrome in children and adolescents with psychotic disorders prior to clozapine and...

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Grover S, Hazari N, Chakrabarti S, et al. Metabolic Disturbances, Side Effect Profile and Effectiveness of Clozapine in Adolescents. Indian J Psychol Med. 2016;38(3):224-33doi: 10.4103/0253-7176.183091.
Grover, S., Hazari, N., Chakrabarti, S., & Avasthi, A. (2016). Metabolic Disturbances, Side Effect Profile and Effectiveness of Clozapine in Adolescents. Indian journal of psychological medicine, 38(3), 224-33. https://doi.org/10.4103/0253-7176.183091
Grover, Sandeep, et al. "Metabolic Disturbances, Side Effect Profile and Effectiveness of Clozapine in Adolescents." Indian journal of psychological medicine vol. 38,3 (2016): 224-33. doi: https://doi.org/10.4103/0253-7176.183091
Grover S, Hazari N, Chakrabarti S, Avasthi A. Metabolic Disturbances, Side Effect Profile and Effectiveness of Clozapine in Adolescents. Indian J Psychol Med. 2016 May-Jun;38(3):224-33. doi: 10.4103/0253-7176.183091. PMID: 27335518; PMCID: PMC4904759.
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Clozapine prescribing in the UK: views and experience of consultant psychiatrists.

Therapeutic advances in psychopharmacology

Tungaraza TE, Farooq S.
PMID: 26240748
Ther Adv Psychopharmacol. 2015 Apr;5(2):88-96. doi: 10.1177/2045125314566808.

OBJECTIVES: It has been repeatedly shown that clozapine is underutilized and there is delayed use of it in clinical practice.METHOD: An online survey was sent to 2771 consultant psychiatrists registered with the Royal College of Psychiatrists in the UK....

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Tungaraza TE, Farooq S. Clozapine prescribing in the UK: views and experience of consultant psychiatrists. Ther Adv Psychopharmacol. 2015;5(2):88-96doi: 10.1177/2045125314566808.
Tungaraza, T. E., & Farooq, S. (2015). Clozapine prescribing in the UK: views and experience of consultant psychiatrists. Therapeutic advances in psychopharmacology, 5(2), 88-96. https://doi.org/10.1177/2045125314566808
Tungaraza, Tongeji E, and Farooq, Saeed. "Clozapine prescribing in the UK: views and experience of consultant psychiatrists." Therapeutic advances in psychopharmacology vol. 5,2 (2015): 88-96. doi: https://doi.org/10.1177/2045125314566808
Tungaraza TE, Farooq S. Clozapine prescribing in the UK: views and experience of consultant psychiatrists. Ther Adv Psychopharmacol. 2015 Apr;5(2):88-96. doi: 10.1177/2045125314566808. PMID: 26240748; PMCID: PMC4521444.
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Showing 1 to 12 of 1389 entries