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Showing 1 to 10 of 10 entries
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Unique characteristics of the Ainu population in Northern Japan.

Journal of human genetics

Jinam TA, Kanzawa-Kiriyama H, Inoue I, Tokunaga K, Omoto K, Saitou N.
PMID: 26178428
J Hum Genet. 2015 Oct;60(10):565-71. doi: 10.1038/jhg.2015.79. Epub 2015 Jul 16.

Various genetic data (classic markers, mitochondrial DNAs, Y chromosomes and genome-wide single-nucleotide polymorphisms (SNPs)) have confirmed the coexistence of three major human populations on the Japanese Archipelago: Ainu in Hokkaido, Ryukyuans in the Southern Islands and Mainland Japanese. We...

Identification of m6A-related genes and m6A RNA methylation regulators in pancreatic cancer and their association with survival.

Annals of translational medicine

Geng Y, Guan R, Hong W, Huang B, Liu P, Guo X, Hu S, Yu M, Hou B.
PMID: 32355831
Ann Transl Med. 2020 Mar;8(6):387. doi: 10.21037/atm.2020.03.98.

BACKGROUND: N6-methyladenosine (m6A) modification holds an important position in tumorigenesis and metastasis because it can change gene expression and even function in multiple levels including RNA splicing, stability, translocation and translation. In present study, we aim to conducted comprehensive...

Serum Levels of ARMS2, COL8A1, RAD51B, and VEGF and their Correlations in Age-related Macular Degeneration.

Current neurovascular research

Battu P, Sharma K, Rain M, Singh R, Anand A.
PMID: 34060991
Curr Neurovasc Res. 2021;18(2):181-188. doi: 10.2174/1567202618666210531130711.

BACKGROUND: Many factors including genetic and environmental are responsible for the incidence of Age-related Macular Degeneration (AMD). However, its pathogenesis has not been clearly elucidated yet.OBJECTIVE: This study aimed to estimate the Age-Related Maculopathy Susceptibility 2 (ARMS2), Collagen type...

Collagen type VIII alpha 2 chain (COL8A2), an important component of the basement membrane of the corneal endothelium, facilitates the malignant development of glioblastoma cells via inducing EMT.

Journal of bioenergetics and biomembranes

Cheng YX, Xiao L, Yang YL, Liu XD, Zhou XR, Bu ZF, Cao PC, Wang DK.
PMID: 33405048
J Bioenerg Biomembr. 2021 Feb;53(1):49-59. doi: 10.1007/s10863-020-09865-1. Epub 2021 Jan 06.

Glioblastoma (GBM) is one of the most lethal tumor of all human cancers. Due to its poor response to chemotherapy and radiotherapy as well as its high rate of recurrence after treatment, the treatment is still undesired. The identification...

Sources of Collagen for Biomaterials in Skin Wound Healing.

Bioengineering (Basel, Switzerland)

Davison-Kotler E, Marshall WS, García-Gareta E.
PMID: 31261996
Bioengineering (Basel). 2019 Jun 30;6(3). doi: 10.3390/bioengineering6030056.

Collagen is the most frequently used protein in the fields of biomaterials and regenerative medicine. Within the skin, collagen type I and III are the most abundant, while collagen type VII is associated with pathologies of the dermal-epidermal junction....

Epidermolysis bullosa acquisita: current diagnosis and therapy.

Dermatology reports

Mehren CR, Gniadecki R.
PMID: 25386290
Dermatol Reports. 2011 Nov 28;3(3):e38. doi: 10.4081/dr.2011.e38. eCollection 2011 Oct 05.

Epidermolysis bullosa acquisita (EBA) is an acquired, autoimmune subepidermal blistering disease with an approximate prevalence of 0,2/million people. The hallmark of EBA is the presence of autoantibodies (mainly IgG class) to anchoring fibril collagen (type VII collagen) located at...

Distribution Patterns of E-Cadherin, Type VII Collagen and Fibronectin in Denture-Related Stomatitis: A Preliminary Study.

The open dentistry journal

Bars PL, Soueidan A.
PMID: 22291862
Open Dent J. 2012;6:14-22. doi: 10.2174/1874210601206010014. Epub 2012 Jan 13.

The distribution of epithelial E-cadherin, basement membrane type VII collagen, and underlying connective tissues fibronectin were investigated immunohistochemically and compared in normal palatal mucosa and in denture-related stomatitis (DRS) derivatives using monoclonal antibodies.Biopsies of palatal mucosa were obtained from...

Clinical value and potential mechanisms of COL8A1 upregulation in breast cancer: a comprehensive analysis.

Cancer cell international

Peng W, Li JD, Zeng JJ, Zou XP, Tang D, Tang W, Rong MH, Li Y, Dai WB, Tang ZQ, Feng ZB, Chen G.
PMID: 32818022
Cancer Cell Int. 2020 Aug 14;20:392. doi: 10.1186/s12935-020-01465-8. eCollection 2020.

BACKGROUND: The situation faced by breast cancer patients, especially those with triple-negative breast cancer, is still grave. More effective therapeutic targets are needed to optimize the clinical management of breast cancer. Although collagen type VIII alpha 1 chain (COL8A1)...

Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (.

Data in brief

Someya T, Sano K, Hara K, Sagane Y, Watanabe T, Wijesekara RGS.
PMID: 29322079
Data Brief. 2017 Dec 20;16:982-992. doi: 10.1016/j.dib.2017.12.035. eCollection 2018 Feb.

This data article provides gene expression profiles, determined by using real-time PCR, of fibroblasts and keratinocytes treated with 0.01% and 0.001% extracts of neem plant (Azadirachta indica), local name "Kohomba" in Sri Lanka, harvested in Sri Lanka. For fibroblasts,...

A Case Report of an Infant with Autosomal Recessive Dystrophic Epidermolysis Bullosa: COL7A1 Gene Mutations at C2005T and G7922A.

Acta dermatovenerologica Croatica : ADC

Liu J, Wang L.
PMID: 34990346
Acta Dermatovenerol Croat. 2021 Dec;29(3):164-166.

A male infant was born by spontaneous delivery on February 7, 2020, with a gestational age of 40 weeks and a birth weight of 4.1 kg. After birth, the infant presented with appearance of skin loss on the bilateral...

Showing 1 to 10 of 10 entries