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Showing 1 to 12 of 2009 entries
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Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin.

Journal of oncology

Sharma C, Vas AJ, Goala P, Gheewala TM, Rizvi TA, Hussain A.
PMID: 24624140
J Oncol. 2014;2014:321754. doi: 10.1155/2014/321754. Epub 2014 Jan 30.

The present study was designed to gain insight into the antiproliferative activity of ethanolic neem leaves extract (ENLE) alone or in combination with cisplatin by cell viability assay on human breast (MCF-7) and cervical (HeLa) cancer cells. Nuclear morphological...

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Sharma C, Vas AJ, Goala P, et al. Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin. J Oncol. 2014;2014:321754doi: 10.1155/2014/321754.
Sharma, C., Vas, A. J., Goala, P., Gheewala, T. M., Rizvi, T. A., & Hussain, A. (2014). Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin. Journal of oncology, 2014321754. https://doi.org/10.1155/2014/321754
Sharma, Chhavi, et al. "Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin." Journal of oncology vol. 2014 (2014): 321754. doi: https://doi.org/10.1155/2014/321754
Sharma C, Vas AJ, Goala P, Gheewala TM, Rizvi TA, Hussain A. Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin. J Oncol. 2014;2014:321754. doi: 10.1155/2014/321754. Epub 2014 Jan 30. PMID: 24624140; PMCID: PMC3929266.
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Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats.

Evidence-based complementary and alternative medicine : eCAM

Park E, Lee MY, Jeon WY, Lee N, Seo CS, Shin HK.
PMID: 27504137
Evid Based Complement Alternat Med. 2016;2016:1428923. doi: 10.1155/2016/1428923. Epub 2016 Jul 18.

Yongdamsagan-tang, a traditional herbal formula, is used widely for the treatment of inflammation and viral diseases. In this study, we investigated whether Yongdamsagan-tang water extract (YSTE) affects testosterone propionate- (TP-) induced benign prostatic hyperplasia (BPH) in a rat model....

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Park E, Lee MY, Jeon WY, et al. Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats. Evid Based Complement Alternat Med. 2016;2016:1428923doi: 10.1155/2016/1428923.
Park, E., Lee, M. Y., Jeon, W. Y., Lee, N., Seo, C. S., & Shin, H. K. (2016). Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats. Evidence-based complementary and alternative medicine : eCAM, 20161428923. https://doi.org/10.1155/2016/1428923
Park, Eunsook, et al. "Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats." Evidence-based complementary and alternative medicine : eCAM vol. 2016 (2016): 1428923. doi: https://doi.org/10.1155/2016/1428923
Park E, Lee MY, Jeon WY, Lee N, Seo CS, Shin HK. Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats. Evid Based Complement Alternat Med. 2016;2016:1428923. doi: 10.1155/2016/1428923. Epub 2016 Jul 18. PMID: 27504137; PMCID: PMC4967681.
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Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo.

International journal of clinical and experimental medicine

Yu Y, Pei M, Li L.
PMID: 26309548
Int J Clin Exp Med. 2015 Jun 15;8(6):8958-67. eCollection 2015.

Baicalin is a flavonoid glycoside extracted from a kind of traditional Chinese drug, Scutellaria baicalensis, and possesses multiple pharmacological activities. The present study was designed to investigate the effects and mechanisms of baicalin against hepatic cancer cell growth and...

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Yu Y, Pei M, Li L. Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo. Int J Clin Exp Med. 2015;8(6):8958-67
Yu, Y., Pei, M., & Li, L. (2015). Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo. International journal of clinical and experimental medicine, 8(6), 8958-67.
Yu, Yang, et al. "Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo." International journal of clinical and experimental medicine vol. 8,6 (2015): 8958-67.
Yu Y, Pei M, Li L. Baicalin induces apoptosis in hepatic cancer cells in vitro and suppresses tumor growth in vivo. Int J Clin Exp Med. 2015 Jun 15;8(6):8958-67. eCollection 2015. PMID: 26309548; PMCID: PMC4538000.
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Cyclin D1 G870A polymorphism and glioma risk in a Chinese population.

International journal of clinical and experimental medicine

Liu H, Song Z, Liao DG, Zhang TY, Liu F, Zheng W, Luo K, Yang L.
PMID: 26309688
Int J Clin Exp Med. 2015 Jun 15;8(6):9991-5. eCollection 2015.

BACKGROUND: A number of studies have suggested that the Cyclin D1 (CCND1) G870A polymorphism was associated with susceptibility to various cancers. In the present study, we aimed to investigate the association between CCND1 G870A polymorphism and the risk of...

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Liu H, Song Z, Liao DG, et al. Cyclin D1 G870A polymorphism and glioma risk in a Chinese population. Int J Clin Exp Med. 2015;8(6):9991-5
Liu, H., Song, Z., Liao, D. G., Zhang, T. Y., Liu, F., Zheng, W., Luo, K., & Yang, L. (2015). Cyclin D1 G870A polymorphism and glioma risk in a Chinese population. International journal of clinical and experimental medicine, 8(6), 9991-5.
Liu, Hao, et al. "Cyclin D1 G870A polymorphism and glioma risk in a Chinese population." International journal of clinical and experimental medicine vol. 8,6 (2015): 9991-5.
Liu H, Song Z, Liao DG, Zhang TY, Liu F, Zheng W, Luo K, Yang L. Cyclin D1 G870A polymorphism and glioma risk in a Chinese population. Int J Clin Exp Med. 2015 Jun 15;8(6):9991-5. eCollection 2015. PMID: 26309688; PMCID: PMC4538148.
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TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer.

Oncotarget

Liu L, Zhou XM, Yang FF, Miao Y, Yin Y, Hu XJ, Hou G, Wang QY, Kang J.
PMID: 28977927
Oncotarget. 2017 Jul 01;8(37):62069-62080. doi: 10.18632/oncotarget.18911. eCollection 2017 Sep 22.

Expression pattern and biological roles of TRIM22 remains unknown in most human cancers. The present study aims to discover its clinical significance and function in human non-small cell lung cancer (NSCLC). Immunohistochemistry was used to examine TRIM22 expression in...

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Liu L, Zhou XM, Yang FF, et al. TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer. Oncotarget. 2017;8(37):62069-62080doi: 10.18632/oncotarget.18911.
Liu, L., Zhou, X. M., Yang, F. F., Miao, Y., Yin, Y., Hu, X. J., Hou, G., Wang, Q. Y., & Kang, J. (2017). TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer. Oncotarget, 8(37), 62069-62080. https://doi.org/10.18632/oncotarget.18911
Liu, Li, et al. "TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer." Oncotarget vol. 8,37 (2017): 62069-62080. doi: https://doi.org/10.18632/oncotarget.18911
Liu L, Zhou XM, Yang FF, Miao Y, Yin Y, Hu XJ, Hou G, Wang QY, Kang J. TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer. Oncotarget. 2017 Jul 01;8(37):62069-62080. doi: 10.18632/oncotarget.18911. eCollection 2017 Sep 22. PMID: 28977927; PMCID: PMC5617487.
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Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells.

BMC complementary and alternative medicine

Park GH, Sung JH, Song HM, Jeong JB.
PMID: 27670681
BMC Complement Altern Med. 2016 Sep 26;16(1):373. doi: 10.1186/s12906-016-1364-x.

BACKGROUND: Psoralea Fructus (PF), the dried and ripe fruit of Psoralea corylifolia exhibits an anti-cancer activity. However, the molecular mechanisms by which PF inhibits the proliferation of cancer cells have not been elucidated in detail. Cyclin D1 and CDK4...

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Park GH, Sung JH, Song HM, et al. Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells. BMC Complement Altern Med. 2016;16(1):373doi: 10.1186/s12906-016-1364-x.
Park, G. H., Sung, J. H., Song, H. M., & Jeong, J. B. (2016). Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells. BMC complementary and alternative medicine, 16(1), 373. https://doi.org/10.1186/s12906-016-1364-x
Park, Gwang Hun, et al. "Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells." BMC complementary and alternative medicine vol. 16,1 (2016): 373. doi: https://doi.org/10.1186/s12906-016-1364-x
Park GH, Sung JH, Song HM, Jeong JB. Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells. BMC Complement Altern Med. 2016 Sep 26;16(1):373. doi: 10.1186/s12906-016-1364-x. PMID: 27670681; PMCID: PMC5037586.
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Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas.

OncoTargets and therapy

Cong D, He M, Chen S, Liu X, Liu X, Sun H.
PMID: 26345235
Onco Targets Ther. 2015 Aug 26;8:2271-7. doi: 10.2147/OTT.S85753. eCollection 2015.

In the present study, we analyzed microRNA (miRNA) and gene expression profiles using 499 papillary thyroid carcinoma (PTC) samples and 58 normal thyroid tissues obtained from The Cancer Genome Atlas database. A pivotal regulatory network of 18 miRNA and...

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Cong D, He M, Chen S, et al. Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas. Onco Targets Ther. 2015;8:2271-7doi: 10.2147/OTT.S85753.
Cong, D., He, M., Chen, S., Liu, X., Liu, X., & Sun, H. (2015). Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas. OncoTargets and therapy, 82271-7. https://doi.org/10.2147/OTT.S85753
Cong, Dan, et al. "Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas." OncoTargets and therapy vol. 8 (2015): 2271-7. doi: https://doi.org/10.2147/OTT.S85753
Cong D, He M, Chen S, Liu X, Liu X, Sun H. Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas. Onco Targets Ther. 2015 Aug 26;8:2271-7. doi: 10.2147/OTT.S85753. eCollection 2015. PMID: 26345235; PMCID: PMC4556042.
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Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.

American journal of cancer research

Kumar G, Patlolla JM, Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Singh A, Gillaspy A, Lightfoot S, Steele VE, Kopelovich L, Rao CV.
PMID: 27293987
Am J Cancer Res. 2016 May 01;6(5):894-909. eCollection 2016.

Lung cancer is the leading cause of cancer deaths worldwide. Targeting complementary pathways will achieve better treatment efficacy than a single agent high-dose strategy that could increase risk of side effects and tumor resistance. To target COX-2, 5-LOX, and...

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Kumar G, Patlolla JM, Madka V, et al. Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice. Am J Cancer Res. 2016;6(5):894-909
Kumar, G., Patlolla, J. M., Madka, V., Mohammed, A., Li, Q., Zhang, Y., Biddick, L., Singh, A., Gillaspy, A., Lightfoot, S., Steele, V. E., Kopelovich, L., & Rao, C. V. (2016). Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice. American journal of cancer research, 6(5), 894-909.
Kumar, Gaurav, et al. "Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice." American journal of cancer research vol. 6,5 (2016): 894-909.
Kumar G, Patlolla JM, Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Singh A, Gillaspy A, Lightfoot S, Steele VE, Kopelovich L, Rao CV. Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice. Am J Cancer Res. 2016 May 01;6(5):894-909. eCollection 2016. PMID: 27293987; PMCID: PMC4889708.
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Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer.

Journal of Cancer

Quan Y, Xu M, Cui P, Ye M, Zhuang B, Min Z.
PMID: 25767604
J Cancer. 2015 Feb 15;6(4):342-50. doi: 10.7150/jca.10969. eCollection 2015.

GRHL2 was implicated in regulating cancer development. Our previous study demonstrated that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by targeting ZEB1. It is unclear whether GRHL2 expression may have diagnostic or prognostic value in colorectal...

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Quan Y, Xu M, Cui P, et al. Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer. J Cancer. 2015;6(4):342-50doi: 10.7150/jca.10969.
Quan, Y., Xu, M., Cui, P., Ye, M., Zhuang, B., & Min, Z. (2015). Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer. Journal of Cancer, 6(4), 342-50. https://doi.org/10.7150/jca.10969
Quan, Yingjun, et al. "Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer." Journal of Cancer vol. 6,4 (2015): 342-50. doi: https://doi.org/10.7150/jca.10969
Quan Y, Xu M, Cui P, Ye M, Zhuang B, Min Z. Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer. J Cancer. 2015 Feb 15;6(4):342-50. doi: 10.7150/jca.10969. eCollection 2015. PMID: 25767604; PMCID: PMC4349874.
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Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells.

Oncology letters

Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, Yang Z, Cao R, Tao H, Wang X, Zhou J.
PMID: 26870186
Oncol Lett. 2016 Jan;11(1):182-188. doi: 10.3892/ol.2015.3854. Epub 2015 Nov 02.

The present study investigated the anti-tumor activity of N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carbox-amide (BCTC), a potent and specific inhibitor of transient receptor potential cation channel subfamily M member 8 (TRPM8) in prostate cancer (PCa) DU145 cells. TRPM8 expression in DU145 and normal prostate...

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Liu T, Fang Z, Wang G, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2015;11(1):182-188doi: 10.3892/ol.2015.3854.
Liu, T., Fang, Z., Wang, G., Shi, M., Wang, X., Jiang, K., Yang, Z., Cao, R., Tao, H., Wang, X., & Zhou, J. (2016). Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncology letters, 11(1), 182-188. https://doi.org/10.3892/ol.2015.3854
Liu, Tao, et al. "Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells." Oncology letters vol. 11,1 (2016): 182-188. doi: https://doi.org/10.3892/ol.2015.3854
Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, Yang Z, Cao R, Tao H, Wang X, Zhou J. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016 Jan;11(1):182-188. doi: 10.3892/ol.2015.3854. Epub 2015 Nov 02. PMID: 26870186; PMCID: PMC4727066.
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Development and characterization of a new human hepatic cell line.

EXCLI journal

Ramboer E, De Craene B, De Kock J, Berx G, Rogiers V, Vanhaecke T, Vinken M.
PMID: 26869867
EXCLI J. 2015 Jul 28;14:875-89. doi: 10.17179/excli2015-424. eCollection 2015.

The increasing demand and hampered use of primary human hepatocytes for research purposes have urged scientists to search for alternative cell sources, such as immortalized hepatic cell lines. The aim of this study was to develop a human hepatic...

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Ramboer E, De Craene B, De Kock J, et al. Development and characterization of a new human hepatic cell line. EXCLI J. 2015;14:875-89doi: 10.17179/excli2015-424.
Ramboer, E., De Craene, B., De Kock, J., Berx, G., Rogiers, V., Vanhaecke, T., & Vinken, M. (2015). Development and characterization of a new human hepatic cell line. EXCLI journal, 14875-89. https://doi.org/10.17179/excli2015-424
Ramboer, Eva, et al. "Development and characterization of a new human hepatic cell line." EXCLI journal vol. 14 (2015): 875-89. doi: https://doi.org/10.17179/excli2015-424
Ramboer E, De Craene B, De Kock J, Berx G, Rogiers V, Vanhaecke T, Vinken M. Development and characterization of a new human hepatic cell line. EXCLI J. 2015 Jul 28;14:875-89. doi: 10.17179/excli2015-424. eCollection 2015. PMID: 26869867; PMCID: PMC4747020.
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MiR-202 promotes endometriosis by regulating SOX6 expression.

International journal of clinical and experimental medicine

Zhang D, Li Y, Tian J, Zhang H, Wang S.
PMID: 26770366
Int J Clin Exp Med. 2015 Oct 15;8(10):17757-64. eCollection 2015.

OBJECTIVES: This study is to investigate the role and mechanism of microRNA-202 (miR-202) in endometriosis.METHODS: Forty-five cases of ectopic endometrial tissues, 25 cases of eutopic endometrial tissues and 26 cases of normal endometrial tissues were collected. MiR-202 expression was...

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Zhang D, Li Y, Tian J, et al. MiR-202 promotes endometriosis by regulating SOX6 expression. Int J Clin Exp Med. 2015;8(10):17757-64
Zhang, D., Li, Y., Tian, J., Zhang, H., & Wang, S. (2015). MiR-202 promotes endometriosis by regulating SOX6 expression. International journal of clinical and experimental medicine, 8(10), 17757-64.
Zhang, Dongli, et al. "MiR-202 promotes endometriosis by regulating SOX6 expression." International journal of clinical and experimental medicine vol. 8,10 (2015): 17757-64.
Zhang D, Li Y, Tian J, Zhang H, Wang S. MiR-202 promotes endometriosis by regulating SOX6 expression. Int J Clin Exp Med. 2015 Oct 15;8(10):17757-64. eCollection 2015. PMID: 26770366; PMCID: PMC4694266.
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Showing 1 to 12 of 2009 entries