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Showing 1 to 12 of 98 entries
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Efficacy and safety of metformin or oral contraceptives, or both in polycystic ovary syndrome.

Therapeutics and clinical risk management

Yang YM, Choi EJ.
PMID: 26366087
Ther Clin Risk Manag. 2015 Sep 01;11:1345-53. doi: 10.2147/TCRM.S89737. eCollection 2015.

BACKGROUND: Polycystic ovary syndrome (PCOS) is an endocrinopathy that affects approximately 10% of reproductive-aged women throughout their lives. Women with PCOS present with heterogeneous symptoms including ovulatory dysfunction, hyperandrogenism, and polycystic ovaries. Therefore, lifelong individualized management should be considered....

Effect of type of opponent on aggression in male mice with particular reference to studies with antihormones.

Behavioural processes

Martinez M, Simon VM, Castaño D, Brain PF.
PMID: 24925787
Behav Processes. 1989 Dec;20(1):125-37. doi: 10.1016/0376-6357(89)90018-1.

The potential influence of the type of opponent used in intermale aggression encounters to assess the actions of drugs was examined. Two experiments were carried out, one with the antiandrogen Cyproterone Acetate and the other with the antioestrogen CI-680...

Antirenotropic action of antiandrogens cyproterone acetate, casodex, flutamide and epitestosterone.

Endocrine regulations

Starka L, Broulik PD, Hampl R, Nedvidkova J, Hill M.
PMID: 10979040
Endocr Regul. 1996 Jun;30(2):93-97.

The antirenotropic activities of three antiandrogens which are frequently used in the clinical praxis (cyproterone acetate, flutamide and casodex) and of natural endogenous antiandrogen epitestosterone were compared. The substances were administered in oil intraperitoneally to intact male mice. The...

Steroidal versus nonsteroidal antiandrogens in the management of prostate cancer.

The Canadian journal of urology

Trachtenberg J, Farival-Mohseni H, Jewett MA.
PMID: 12741967
Can J Urol. 1996 Sep;3(3):240-245.

The four antiandrogens currently available (cyproterone acetate, flutamide, nilutamide and bilcalutamide) are reviewed relative to their structure, pharmacology and clinical effect.

Flare Associated with LHRH-Agonist Therapy.

Reviews in urology

Thompson IM.
PMID: 16986003
Rev Urol. 2001;3:S10-4.

The most common form of hormonal treatment for prostate cancer is luteinizing hormone-releasing hormone (LHRH)-agonist therapy. During the first 1 to 3 weeks of LHRH-agonist therapy, an initial increase in testosterone is associated with a condition known as "flare."...

Sensitive detection of growth stimulating tumour promoters in perifused primary rat hepatocyte cultures.

Toxicology in vitro : an international journal published in association with BIBRA

Klein S, Gebhardt R.
PMID: 20654349
Toxicol In Vitro. 1997 Oct;11(5):543-7. doi: 10.1016/s0887-2333(97)00063-5.

Comparison of stationary cultivation with discrete changes of the medium with perifusion, where the hepatocytes are cultivated under a continuous flow of medium showed an enhanced sensitivity of perifused hepatocytes towards the mitogen cyproterone acetate (CPA) and the potential...

Specific binding of 11-ketotestosterone in an androgen target organ, the kidney of the male three-spined stickleback,Gasterosteus aculeatus.

Fish physiology and biochemistry

Jakobsson S, Mayer I, Schulz RW, Blankenstein MA, Borg B.
PMID: 24194355
Fish Physiol Biochem. 1996 Dec;15(6):459-67. doi: 10.1007/BF01874920.

The kidney of male three-spined stickleback,Gasterosteus aculeatus, hypertrophies during the breeding season and produces a "glue" which is used in the building of the nest. This hypertrophy is androgen dependent, with 11-ketotestosterone (11KT) being more effective than other tested...

The use of cyproterone acetate in a forensic psychiatric cohort of male sex offenders and its associations with sexual activity and sexual functioning.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa

Lippi G, van Staden PJ.
PMID: 30263177
S Afr J Psychiatr. 2017 Mar 10;23:982. doi: 10.4102/sajpsychiatry.v23i0.982. eCollection 2017.

BACKGROUND: Cyproterone acetate (CPA) is a steroidal anti-androgenic medication used in the field of psychiatry for the treatment of paraphilic disorders, hypersexuality, and inappropriate sexual behaviour which may be present in patients with disorders such as mild and major...

Spotlight on a New Heme Oxygenase Pathway: Testosterone-Induced Shifts in Cardiac Oxidant/Antioxidant Status.

Antioxidants (Basel, Switzerland)

Szabó R, Börzsei D, Kupai K, Hoffmann A, Gesztelyi R, Magyariné Berkó A, Varga C, Pósa A.
PMID: 31394727
Antioxidants (Basel). 2019 Aug 07;8(8). doi: 10.3390/antiox8080288.

A low testosterone level contributes to the development of oxidative damages; however, the cardiovascular effects of exogenous hormone therapy are not well elucidated. The aim of our work is to study the association of the testosterone level, antioxidant/oxidant system,...

Is there a role for 5α-reductase inhibitors in transgender individuals?.

Andrology

Irwig MS.
PMID: 32749751
Andrology. 2021 Nov;9(6):1729-1731. doi: 10.1111/andr.12881. Epub 2020 Sep 02.

This commentary will explore the important clinical question regarding whether the antiandrogen class of 5α-reductase inhibitors should be considered as an effective and safe treatment option for transfeminine and/or transmasculine individuals. The use of finasteride in transfeminine individuals is...

Sorption, transport, and transformation of natural and synthetic progestins in soil-water systems.

Journal of hazardous materials

Yang X, Lin H, Dai X, Zhang Z, Gong B, Hu Z, Jiang X, Li Y.
PMID: 31668762
J Hazard Mater. 2020 Feb 15;384:121482. doi: 10.1016/j.jhazmat.2019.121482. Epub 2019 Oct 18.

Natural and synthetic progestins are emerging endocrine disruptors that can be transported from livestock farms and agricultural fields to receiving waters via surface runoff. The transformation of progestins during transport is expected to affect the efficiencies of runoff management...

Influence of circulating testosterone concentration on sperm cryoresistance: The ibex as an experimental model.

Andrology

Bóveda P, Esteso MC, Velázquez R, Castaño C, Toledano-Díaz A, López-Sebastián A, Mejía O, Millán de la Blanca MG, Ungerfeld R, Santiago-Moreno J.
PMID: 33686789
Andrology. 2021 Jul;9(4):1242-1253. doi: 10.1111/andr.12998. Epub 2021 Mar 22.

BACKGROUND: Recent studies have noted that the circulating testosterone concentration may affect the ability of spermatozoa to survive cryopreservation. However, few attempts to confirm such a relationship have been made. Wild ruminant species have very marked seasonal changes in...

Showing 1 to 12 of 98 entries