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Showing 1 to 12 of 666 entries
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Identifying psychosocial interventions that improve both physical and mental health in patients with diabetes: a systematic review and meta-analysis.

Diabetes care

Harkness E, Macdonald W, Valderas J, Coventry P, Gask L, Bower P.
PMID: 20351228
Diabetes Care. 2010 Apr;33(4):926-30. doi: 10.2337/dc09-1519.

OBJECTIVE: Patients with diabetes suffer high rates of mental health problems, and this combination is associated with poor outcomes. Although effective treatments exist for both diabetes and mental health problems, delivering services for physical and mental health problems separately...

Measuring neurodevelopmental outcome in neonatal trials: a continuing and increasing challenge.

Archives of disease in childhood. Fetal and neonatal edition

Marlow N.
PMID: 23839983
Arch Dis Child Fetal Neonatal Ed. 2013 Nov;98(6):F554-8. doi: 10.1136/archdischild-2012-302970. Epub 2013 Jul 09.

The need for outcome evaluations as part of clinical trials has never been greater. In this paper, issues around the design and data collection of such outcome evaluations are discussed in relation to how they may be best collected...

The ENIGMA-Epilepsy working group: Mapping disease from large data sets.

Human brain mapping

Sisodiya SM, Whelan CD, Hatton SN, Huynh K, Altmann A, Ryten M, Vezzani A, Caligiuri ME, Labate A, Gambardella A, Ives-Deliperi V, Meletti S, Munsell BC, Bonilha L, Tondelli M, Rebsamen M, Rummel C, Vaudano AE, Wiest R, Balachandra AR, Bargalló N, Bartolini E, Bernasconi A, Bernasconi N, Bernhardt B, Caldairou B, Carr SJA, Cavalleri GL, Cendes F, Concha L, Desmond PM, Domin M, Duncan JS, Focke NK, Guerrini R, Hamandi K, Jackson GD, Jahanshad N, Kälviäinen R, Keller SS, Kochunov P, Kowalczyk MA, Kreilkamp BAK, Kwan P, Lariviere S, Lenge M, Lopez SM, Martin P, Mascalchi M, Moreira JCV, Morita-Sherman ME, Pardoe HR, Pariente JC, Raviteja K, Rocha CS, Rodríguez-Cruces R, Seeck M, Semmelroch MKHG, Sinclair B, Soltanian-Zadeh H, Stein DJ, Striano P, Taylor PN, Thomas RH, Thomopoulos SI, Velakoulis D, Vivash L, Weber B, Yasuda CL, Zhang J, Thompson PM, McDonald CR.
PMID: 32468614
Hum Brain Mapp. 2020 May 29; doi: 10.1002/hbm.25037. Epub 2020 May 29.

Epilepsy is a common and serious neurological disorder, with many different constituent conditions characterized by their electro clinical, imaging, and genetic features. MRI has been fundamental in advancing our understanding of brain processes in the epilepsies. Smaller-scale studies have...

Kidney outcomes for children with lupus nephritis.

Pediatric nephrology (Berlin, Germany)

Oni L, Wright RD, Marks S, Beresford MW, Tullus K.
PMID: 32725543
Pediatr Nephrol. 2021 Jun;36(6):1377-1385. doi: 10.1007/s00467-020-04686-1. Epub 2020 Jul 28.

Systemic lupus erythematosus is a rare lifelong multi-systemic autoimmune condition. Juvenile-onset SLE (JSLE) is recognized to have a more active disease course when compared with adult-onset disease and patients have a worse long-term survival. Kidney involvement occurs in over...

Development of a predictive risk model for school readiness at age 3 years using the UK Millennium Cohort Study.

BMJ open

Camacho C, Straatmann VS, Day JC, Taylor-Robinson D.
PMID: 31213442
BMJ Open. 2019 Jun 17;9(6):e024851. doi: 10.1136/bmjopen-2018-024851.

OBJECTIVES: The aim of this study is to develop a predictive risk model (PRM) for school readiness measured at age 3 years using perinatal and early infancy data.DESIGN AND PARTICIPANTS: This paper describes the development of a PRM. Predictors...

Does the carer support needs assessment tool cover the established support needs of carers of patients with chronic obstructive pulmonary disease? A systematic literature search and narrative review.

Palliative medicine

Micklewright K, Farquhar M.
PMID: 32669040
Palliat Med. 2020 Dec;34(10):1305-1315. doi: 10.1177/0269216320939243. Epub 2020 Jul 16.

BACKGROUND: Informal carers play a key supportive role for patients with chronic obstructive pulmonary disease. However, caring can have a considerable impact on health and wellbeing. Carers may have unidentified support needs that could be a target for intervention....

Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study.

PloS one

Pontikos N, Chua S, Foster PJ, Tuft SJ, Day AC.
PMID: 31536508
PLoS One. 2019 Sep 19;14(9):e0218144. doi: 10.1371/journal.pone.0218144. eCollection 2019.

PURPOSE: To describe corneal astigmatism in the UK Biobank population and to look for associations with other biometric variables and socio-demographic factors.METHODS: This analysis included a subsample of 107,452 participants of the UK Biobank study who underwent an enhanced...

Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study.

European journal of preventive cardiology

Zaccardi F, Franks PW, Dudbridge F, Davies MJ, Khunti K, Yates T.
PMID: 34247229
Eur J Prev Cardiol. 2021 Jul 10;28(7):704-712. doi: 10.1177/2047487319885041.

AIMS: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known.METHODS: Information on usual walking pace (self-defined as slow, steady/average, or...

Individualized ablation strategy to treat persistent atrial fibrillation: Core-to-boundary approach guided by charge-density mapping.

Heart rhythm

Shi R, Chen Z, Pope MTB, Zaman JAB, Debney M, Marinelli A, Boyalla V, Sathishkumar A, Karim N, Cantor E, Valli H, Haldar S, Jones DG, Hussain W, Markides V, Betts TR, Wong T.
PMID: 33610744
Heart Rhythm. 2021 Jun;18(6):862-870. doi: 10.1016/j.hrthm.2021.02.014. Epub 2021 Feb 19.

BACKGROUND: Noncontact charge-density mapping allows rapid real-time global mapping of atrial fibrillation (AF), offering the opportunity for a personalized ablation strategy.OBJECTIVE: The purpose of this study was to compare the 2-year outcome of an individualized strategy consisting of pulmonary...

A replication study separates polymorphisms behind migraine with and without depression.

PloS one

Petschner P, Baksa D, Hullam G, Torok D, Millinghoffer A, Deakin JFW, Bagdy G, Juhasz G.
PMID: 34972135
PLoS One. 2021 Dec 31;16(12):e0261477. doi: 10.1371/journal.pone.0261477. eCollection 2021.

The largest migraine genome-wide association study identified 38 candidate loci. In this study we assessed whether these results replicate on a gene level in our European cohort and whether effects are altered by lifetime depression. We tested SNPs of...

Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A.

The Journal of experimental medicine

Lepelley A, Della Mina E, Van Nieuwenhove E, Waumans L, Fraitag S, Rice GI, Dhir A, Frémond ML, Rodero MP, Seabra L, Carter E, Bodemer C, Buhas D, Callewaert B, de Lonlay P, De Somer L, Dyment DA, Faes F, Grove L, Holden S, Hully M, Kurian MA, McMillan HJ, Suetens K, Tyynismaa H, Chhun S, Wai T, Wouters C, Bader-Meunier B, Crow YJ.
PMID: 34387651
J Exp Med. 2021 Oct 04;218(10). doi: 10.1084/jem.20201560. Epub 2021 Aug 13.

Mitochondrial DNA (mtDNA) has been suggested to drive immune system activation, but the induction of interferon signaling by mtDNA has not been demonstrated in a Mendelian mitochondrial disease. We initially ascertained two patients, one with a purely neurological phenotype...

Serum C-Reactive Protein and Periodontitis: A Systematic Review and Meta-Analysis.

Frontiers in immunology

Machado V, Botelho J, Escalda C, Hussain SB, Luthra S, Mascarenhas P, Orlandi M, Mendes JJ, D'Aiuto F.
PMID: 34394107
Front Immunol. 2021 Jul 28;12:706432. doi: 10.3389/fimmu.2021.706432. eCollection 2021.

Periodontitis has been associated with low-grade inflammation as assessed by C-reactive protein (CRP) levels and its treatment can decrease CRP serum levels. The aim of this systematic review was to critically appraise the evidence comparing CRP serum levels (standard...

Showing 1 to 12 of 666 entries