Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 7 of 7 entries
Sorted by: Best Match Show Resources per page
Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

Cite
Yasuma R, Cicatiello V, Mizutani T, et al. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1doi: 10.1038/sigtrans.2015.2.
Yasuma, R., Cicatiello, V., Mizutani, T., Tudisco, L., Kim, Y., Tarallo, V., Bogdanovich, S., Hirano, Y., Kerur, N., Li, S., Yasuma, T., Fowler, B. J., Wright, C. B., Apicella, I., Greco, A., Brunetti, A., Ambati, B. K., Helmers, S. B., Lundberg, I. E., Viklicky, O., Leusen, J. H., Verbeek, J. S., Gelfand, B. D., Bastos-Carvalho, A., De Falco, S., & Ambati, J. (2016). Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal transduction and targeted therapy, 1. https://doi.org/10.1038/sigtrans.2015.2
Yasuma, Reo, et al. "Intravenous immune globulin suppresses angiogenesis in mice and humans." Signal transduction and targeted therapy vol. 1 (2016). doi: https://doi.org/10.1038/sigtrans.2015.2
Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28. PMID: 26925256; PMCID: PMC4768485.
Copy Download .nbib Format: NLM
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

Science immunology

Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J.
PMID: 34860583
Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03.

[Figure: see text].

Cite
Wang SB, Narendran S, Hirahara S, et al. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021;6(66):eabi4493doi: 10.1126/sciimmunol.abi4493.
Wang, S. B., Narendran, S., Hirahara, S., Varshney, A., Pereira, F., Apicella, I., Ambati, M., Ambati, V. L., Yerramothu, P., Ambati, K., Nagasaka, Y., Argyle, D., Huang, P., Baker, K. L., Marion, K. M., Gupta, K., Liu, B., Hinton, D. R., Canna, S. W., Sallam, T., Sadda, S. R., Kerur, N., Gelfand, B. D., & Ambati, J. (2021). DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology, 6(66), eabi4493. https://doi.org/10.1126/sciimmunol.abi4493
Wang, Shao-Bin, et al. "DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs." Science immunology vol. 6,66 (2021): eabi4493. doi: https://doi.org/10.1126/sciimmunol.abi4493
Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03. PMID: 34860583.
Copy Download .nbib Format: NLM
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.

Nature communications

Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N.
PMID: 34707113
Nat Commun. 2021 Oct 27;12(1):6207. doi: 10.1038/s41467-021-26240-9.

Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), produced by cyclic GMP-AMP synthase (cGAS), stimulates the production of type I interferons (IFN). Here we show that cGAMP activates DNA damage response (DDR) signaling independently of its canonical IFN pathways. Loss of cGAS...

Cite
Banerjee D, Langberg K, Abbas S, et al. A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. Nat Commun. 2021;12(1):6207doi: 10.1038/s41467-021-26240-9.
Banerjee, D., Langberg, K., Abbas, S., Odermatt, E., Yerramothu, P., Volaric, M., Reidenbach, M. A., Krentz, K. J., Rubinstein, C. D., Brautigan, D. L., Abbas, T., Gelfand, B. D., Ambati, J., & Kerur, N. (2021). A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. Nature communications, 12(1), 6207. https://doi.org/10.1038/s41467-021-26240-9
Banerjee, Daipayan, et al. "A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling." Nature communications vol. 12,1 (2021): 6207. doi: https://doi.org/10.1038/s41467-021-26240-9
Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N. A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. Nat Commun. 2021 Oct 27;12(1):6207. doi: 10.1038/s41467-021-26240-9. PMID: 34707113; PMCID: PMC8551335.
Copy Download .nbib Format: NLM
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

Science immunology

Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J.
PMID: 34860583
Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03.

[Figure: see text].

Cite
Wang SB, Narendran S, Hirahara S, et al. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021;6(66):eabi4493doi: 10.1126/sciimmunol.abi4493.
Wang, S. B., Narendran, S., Hirahara, S., Varshney, A., Pereira, F., Apicella, I., Ambati, M., Ambati, V. L., Yerramothu, P., Ambati, K., Nagasaka, Y., Argyle, D., Huang, P., Baker, K. L., Marion, K. M., Gupta, K., Liu, B., Hinton, D. R., Canna, S. W., Sallam, T., Sadda, S. R., Kerur, N., Gelfand, B. D., & Ambati, J. (2021). DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology, 6(66), eabi4493. https://doi.org/10.1126/sciimmunol.abi4493
Wang, Shao-Bin, et al. "DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs." Science immunology vol. 6,66 (2021): eabi4493. doi: https://doi.org/10.1126/sciimmunol.abi4493
Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03. PMID: 34860583.
Copy Download .nbib Format: NLM
Human IgG1 antibodies suppress angiogenesis in a target-independent manner.

Signal transduction and targeted therapy

Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J.
PMID: 26918197
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.1. Epub 2016 Jan 28.

Aberrant angiogenesis is implicated in diseases affecting nearly 10% of the world's population. The most widely used anti-angiogenic drug is bevacizumab, a humanized IgG1 monoclonal antibody that targets human VEGFA. Although bevacizumab does not recognize mouse Vegfa, it inhibits...

Cite
Bogdanovich S, Kim Y, Mizutani T, et al. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduct Target Ther. 2016;1doi: 10.1038/sigtrans.2015.1.
Bogdanovich, S., Kim, Y., Mizutani, T., Yasuma, R., Tudisco, L., Cicatiello, V., Bastos-Carvalho, A., Kerur, N., Hirano, Y., Baffi, J. Z., Tarallo, V., Li, S., Yasuma, T., Arpitha, P., Fowler, B. J., Wright, C. B., Apicella, I., Greco, A., Brunetti, A., Ruvo, M., Sandomenico, A., Nozaki, M., Ijima, R., Kaneko, H., Ogura, Y., Terasaki, H., Ambati, B. K., Leusen, J. H., Langdon, W. Y., Clark, M. R., Armour, K. L., Bruhns, P., Verbeek, J. S., Gelfand, B. D., De Falco, S., & Ambati, J. (2016). Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal transduction and targeted therapy, 1. https://doi.org/10.1038/sigtrans.2015.1
Bogdanovich, Sasha, et al. "Human IgG1 antibodies suppress angiogenesis in a target-independent manner." Signal transduction and targeted therapy vol. 1 (2016). doi: https://doi.org/10.1038/sigtrans.2015.1
Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.1. Epub 2016 Jan 28. PMID: 26918197; PMCID: PMC4763941.
Copy Download .nbib Format: NLM
[No title available]

Science advances

Fukuda S, Narendran S, Varshney A, Nagasaka Y, Wang SB, Ambati K, Apicella I, Pereira F, Fowler BJ, Yasuma T, Hirahara S, Yasuma R, Huang P, Yerramothu P, Makin RD, Wang M, Baker KL, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Banerjee D, Bonilha VL, Tolstonog GV, Held U, Ogura Y, Terasaki H, Oshika T, Bhattarai D, Kim KB, Feldman SH, Aguirre JI, Hinton DR, Kerur N, Sadda SR, Schumann GG, Gelfand BD, Ambati J.
PMID: 34586848
Sci Adv. 2021 Oct;7(40):eabj3658. doi: 10.1126/sciadv.abj3658. Epub 2021 Sep 29.

[Figure: see text].

Cite
Fukuda S, Narendran S, Varshney A, et al. . Sci Adv. 2021;7(40):eabj3658doi: 10.1126/sciadv.abj3658.
Fukuda, S., Narendran, S., Varshney, A., Nagasaka, Y., Wang, S. B., Ambati, K., Apicella, I., Pereira, F., Fowler, B. J., Yasuma, T., Hirahara, S., Yasuma, R., Huang, P., Yerramothu, P., Makin, R. D., Wang, M., Baker, K. L., Marion, K. M., Huang, X., Baghdasaryan, E., Ambati, M., Ambati, V. L., Banerjee, D., Bonilha, V. L., Tolstonog, G. V., Held, U., Ogura, Y., Terasaki, H., Oshika, T., Bhattarai, D., Kim, K. B., Feldman, S. H., Aguirre, J. I., Hinton, D. R., Kerur, N., Sadda, S. R., Schumann, G. G., Gelfand, B. D., & Ambati, J. (2021). . Science advances, 7(40), eabj3658. https://doi.org/10.1126/sciadv.abj3658
Fukuda, Shinichi, et al. "." Science advances vol. 7,40 (2021): eabj3658. doi: https://doi.org/10.1126/sciadv.abj3658
Fukuda S, Narendran S, Varshney A, Nagasaka Y, Wang SB, Ambati K, Apicella I, Pereira F, Fowler BJ, Yasuma T, Hirahara S, Yasuma R, Huang P, Yerramothu P, Makin RD, Wang M, Baker KL, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Banerjee D, Bonilha VL, Tolstonog GV, Held U, Ogura Y, Terasaki H, Oshika T, Bhattarai D, Kim KB, Feldman SH, Aguirre JI, Hinton DR, Kerur N, Sadda SR, Schumann GG, Gelfand BD, Ambati J. . Sci Adv. 2021 Oct;7(40):eabj3658. doi: 10.1126/sciadv.abj3658. Epub 2021 Sep 29. PMID: 34586848; PMCID: PMC8480932.
Copy Download .nbib Format: NLM
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

Science immunology

Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J.
PMID: 34860583
Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03.

[Figure: see text].

Cite
Wang SB, Narendran S, Hirahara S, et al. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021;6(66):eabi4493doi: 10.1126/sciimmunol.abi4493.
Wang, S. B., Narendran, S., Hirahara, S., Varshney, A., Pereira, F., Apicella, I., Ambati, M., Ambati, V. L., Yerramothu, P., Ambati, K., Nagasaka, Y., Argyle, D., Huang, P., Baker, K. L., Marion, K. M., Gupta, K., Liu, B., Hinton, D. R., Canna, S. W., Sallam, T., Sadda, S. R., Kerur, N., Gelfand, B. D., & Ambati, J. (2021). DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology, 6(66), eabi4493. https://doi.org/10.1126/sciimmunol.abi4493
Wang, Shao-Bin, et al. "DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs." Science immunology vol. 6,66 (2021): eabi4493. doi: https://doi.org/10.1126/sciimmunol.abi4493
Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J. DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Sci Immunol. 2021 Dec 03;6(66):eabi4493. doi: 10.1126/sciimmunol.abi4493. Epub 2021 Dec 03. PMID: 34860583.
Copy Download .nbib Format: NLM
Showing 1 to 7 of 7 entries