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Next steps in the identification of gene targets for type 1 diabetes.

Diabetologia

Grant SFA, Wells AD, Rich SS.
PMID: 32797243
Diabetologia. 2020 Nov;63(11):2260-2269. doi: 10.1007/s00125-020-05248-8. Epub 2020 Aug 14.

The purpose of this review is to provide a view of the future of genomics and other omics approaches in defining the genetic contribution to all stages of risk of type 1 diabetes and the functional impact and clinical...

Analysis of Glucocorticoid-Related Genes Reveal .

Journal of the Endocrine Society

Brenner LN, Mercader JM, Robertson CC, Cole J, Chen L, Jacobs SBR, Rich SS, Florez JC.
PMID: 33150273
J Endocr Soc. 2020 Aug 24;4(11):bvaa121. doi: 10.1210/jendso/bvaa121. eCollection 2020 Nov 01.

Glucocorticoids have multiple therapeutic benefits and are used both for immunosuppression and treatment purposes. Notwithstanding their benefits, glucocorticoid use often leads to hyperglycemia. Owing to the pathophysiologic overlap in glucocorticoid-induced hyperglycemia (GIH) and type 2 diabetes (T2D), we hypothesized...

Showing 1 to 2 of 2 entries