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Showing 1 to 12 of 37 entries
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Aspirin esterase activity - Evidence for skewed distribution in healthy volunteers.

European journal of internal medicine

Adebayo GI, Williams J, Healy S.
PMID: 17574104
Eur J Intern Med. 2007 Jul;18(4):299-303. doi: 10.1016/j.ejim.2006.12.004.

BACKGROUND: Aspirin, with its analgesic, anti-inflammatory, antipyretic, and anti-platelet actions, is one of the most frequently used drugs. Although its use as prophylaxis against thromboembolism is well established, an optimal dose, conferring maximal anti-platelet action without increased risk of...

Pseudocholinesterase polymorphism in an Irish population.

European journal of internal medicine

Adebayo GI, Williams J, Healy S.
PMID: 16275543
Eur J Intern Med. 2005 Nov;16(7):492-5. doi: 10.1016/j.ejim.2005.03.004.

BACKGROUND: Pseudocholinesterase polymorphism, as an example of pharmacogenetics with important clinical implications, has been widely studied and documented. However, data on a sample Irish population is lacking. We sought to provide this.METHOD: In an assay involving Ellman's reaction, pseudocholinesterase...

The intrathecal spread of hyperbaric dibucaine in adolescents.

Journal of anesthesia

Hirabayashi Y, Shimizu R.
PMID: 15278469
J Anesth. 1993 Apr;7(2):167-72. doi: 10.1007/s0054030070167.

We investigated the spread of spinal anesthesia with hyperbaric dibucaine in 20 adolescents aged 9-18 yr and 20 adults aged 23-53 yr. No significant difference was found between the two groups with regard to height, whereas a statistical significant...

2-But-oxy-N-[2-(diethyl-amino)-eth-yl]quinoline-4-carboxamide (dibucaine).

Acta crystallographica. Section E, Structure reports online

Van Eerdenbrugh B, Fanwick PE, Taylor LS.
PMID: 21589483
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 17;66:o3189. doi: 10.1107/S1600536810045460.

The mol-ecular conformation of the title compound, C(20)H(29)N(3)O(2), is stabilized by an intra-molecular C-H⋯O hydrogen bond. The orientation of the amide group to the ring system is characterized by a C-C-C-O dihedral angle of 137.5 (3)°. In the crystal,...

The Effect of Trigger Point Injections on Pain in Patients with Advanced Cancer.

Korean journal of family medicine

Lee CY, Kim EJ, Hwang DG, Jung MY, Cho HG.
PMID: 31487973
Korean J Fam Med. 2019 Sep;40(5):344-347. doi: 10.4082/kjfm.18.0065. Epub 2019 Sep 06.

BACKGROUND: It has been reported that in 62.5% of cases of incurable cancer pain, the complaint is due to myofascial pain syndrome. Trigger point injections using dibucaine hydrochloride help patients with such cancer pain. This study evaluated the efficacy...

Target and Suspect Screening of Pharmaceuticals and Their Transformation Products in the Klip River, South Africa Using Ultra High-Performance Liquid Chromatography-Mass Spectrometry.

Environmental toxicology and chemistry

Madikizela LM, Nuapia YB, Chimuka L, Ncube S, Etale A.
PMID: 34888926
Environ Toxicol Chem. 2021 Dec 09; doi: 10.1002/etc.5265. Epub 2021 Dec 09.

In spite of recent reports on the presence of pharmaceuticals in African water bodies, their prevalence is still not sufficiently quantified. This is because the reports are still few with major focus on a limited number of pharmaceuticals. In...

Irreversible damage to the cauda equina following repeated intrathecal injection of hyperbaric dibucaine.

Journal of anesthesia

Yamauchi Y, Nomoto Y.
PMID: 14517673
J Anesth. 2002;16(2):176-8. doi: 10.1007/s005400200017.

No abstract available.

Accidental subdural catheterization suspected on administration of a test dose of lidocaine and successfully managed by a small dose of dibucaine.

Journal of anesthesia

Adachi Y, Uchihashi Y, Watanabe K, Satoh T.
PMID: 14564622
J Anesth. 1999 Oct 30;13(4):236-9. doi: 10.1007/s005400050063.

No abstract available.

Anesthetics alter the lipid composition of barley-root membranes.

Planta

Jackson PC, St John JB.
PMID: 24253222
Planta. 1984 Nov;162(5):415-21. doi: 10.1007/BF00393453.

The question of whether membrane expansion, which is caused by anesthetics in animal systems, alters the lipid composition of plant cell membranes was investigated. We have measured the effects of several anesthetics on the relative amounts of the principal...

Inhibition of the transthylakoid gradient of electrochemical proton potential by the local anesthetic dibucaine.

Planta

Laasch H, Schumann J, Günther G.
PMID: 24193850
Planta. 1991 Mar;183(4):567-74. doi: 10.1007/BF00194278.

The effects of the local anesthetic dibucaine on coupling between electron transport and ATP synthesis-hydrolysis by the coupling-factor complex (CF0CF1 ATPase) were investigated in thylakoid membranes from Spinacia oleracea L. cv. Monatol. Evidence is presented that inhibition of ATP...

Natural abundance (14)N and (15)N solid-state NMR of pharmaceuticals and their polymorphs.

Physical chemistry chemical physics : PCCP

Veinberg SL, Johnston KE, Jaroszewicz MJ, Kispal BM, Mireault CR, Kobayashi T, Pruski M, Schurko RW.
PMID: 27314503
Phys Chem Chem Phys. 2016 Jun 29;18(26):17713-30. doi: 10.1039/c6cp02855a.

(14)N ultra-wideline (UW), (1)H{(15)N} indirectly-detected HETCOR (idHETCOR) and (15)N dynamic nuclear polarization (DNP) solid-state NMR (SSNMR) experiments, in combination with plane-wave density functional theory (DFT) calculations of (14)N EFG tensors, were utilized to characterize a series of nitrogen-containing active...

Target and Suspect Screening of Pharmaceuticals and their Transformation Products in the Klip River, South Africa, using Ultra-High-Performance Liquid Chromatography-Mass Spectrometry.

Environmental toxicology and chemistry

Madikizela LM, Nuapia YB, Chimuka L, Ncube S, Etale A.
PMID: 34888926
Environ Toxicol Chem. 2021 Dec 09; doi: 10.1002/etc.5265. Epub 2021 Dec 09.

In spite of recent reports about the presence of pharmaceuticals in African water bodies, their prevalence has still not been sufficiently quantified. The few available studies have mostly focused on a limited number of pharmaceuticals. In the present study,...

Showing 1 to 12 of 37 entries