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Showing 1 to 12 of 23 entries
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A calorimetric assay for dicyclomine hydrochloride using bromocresol green.

Journal of pharmaceutical and biomedical analysis

Raggi MA, Cavrini V, Di Pietra AM.
PMID: 16867689
J Pharm Biomed Anal. 1985;3(3):287-91. doi: 10.1016/0731-7085(85)80034-0.

No abstract available.

Pharmacological Basis for the Medicinal Use of Lepidium sativum in Airways Disorders.

Evidence-based complementary and alternative medicine : eCAM

Rehman NU, Khan AU, Alkharfy KM, Gilani AH.
PMID: 22291849
Evid Based Complement Alternat Med. 2012;2012:596524. doi: 10.1155/2012/596524. Epub 2012 Jan 15.

Lepidium sativum is widely used in folk medicine for treatment of hyperactive airways disorders, such as asthma, bronchitis and cough. The crude extract of Lepidium sativum (Ls.Cr) inhibited carbachol (CCh, 1 μM-) and K(+) (80 mM-) induced contractions in...

Multiple Mechanisms of Flaxseed: Effectiveness in Inflammatory Bowel Disease.

Evidence-based complementary and alternative medicine : eCAM

Palla AH, Gilani AU, Bashir S, Ur Rehman N.
PMID: 32765633
Evid Based Complement Alternat Med. 2020 Jul 12;2020:7974835. doi: 10.1155/2020/7974835. eCollection 2020.

MATERIALS AND METHODS: Aqueous-methanolic crude extracts of Flaxseed (Fs.Cr) and Flaxseed oil were tested against 6% acetic acid- (AA-) induced colitis in BALB/c mice. Microscopic damage parameters of the hematoxylin and eosin-stained and periodic acid-Schiff-alcian blue-stained sections of the...

Pain-relieving agents for infantile colic.

The Cochrane database of systematic reviews

Biagioli E, Tarasco V, Lingua C, Moja L, Savino F.
PMID: 27631535
Cochrane Database Syst Rev. 2016 Sep 16;9:CD009999. doi: 10.1002/14651858.CD009999.pub2.

BACKGROUND: Infantile colic is a common disorder in the first months of life, affecting somewhere between 4% and 28% of infants worldwide, depending on geography and definitions used. Although it is self limiting and resolves by four months of...

A First Report of HCTZ and Dicyclomine Induced Uncharacteristic Contraction Alkalosis.

Journal of pharmacy practice

Eid TJ, Horton M, Hendrix C, Yu JM, Browning EA, Malhotra A.
PMID: 34670427
J Pharm Pract. 2021 Oct 20;8971900211052829. doi: 10.1177/08971900211052829. Epub 2021 Oct 20.

BACKGROUND: Contraction alkalosis is characterized by low serum sodium and chloride and high serum carbon dioxide and bicarbonate levels.CASE REPORT: A 28-year-old Caucasian active-duty male with a history of autosomal dominant polycystic kidney disease and diarrhea-predominant Irritable Bowel Syndrome...

Investigation of anti-Parkinson activity of dicyclomine.

The International journal of neuroscience

Sanawar M, Saleem U, Anwar F, Nazir S, Akhtar MF, Ahmad B, Ismail T.
PMID: 32847457
Int J Neurosci. 2020 Sep 11;1-14. doi: 10.1080/00207454.2020.1815732. Epub 2020 Sep 11.

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder. The major causative factors that progress the PD are age, genetic abnormalities, environmental factors and degeneration of dopamine neurons in substantia nigra. PD normally exerts a tonic inhibitory effect on...

Table: Safety of drugs for IBS in pregnancy and lactation (online only).

The Medical letter on drugs and therapeutics

[No authors listed]
PMID: 32324174
Med Lett Drugs Ther. 2020 Mar 23;62(1594):e48-e49.

No abstract available.

Ameliorative effect of galantamine on acetic acid-induced colitis in rats.

Research in pharmaceutical sciences

Mahdavi NS, Talebi A, Minaiyan M.
PMID: 31798655
Res Pharm Sci. 2019 Oct 04;14(5):391-399. doi: 10.4103/1735-5362.268199. eCollection 2019 Oct.

Galantamine (GAL) is a drug for treating Alzheimer's disease which has reasonable and no significant side effects. Studies have shown that GAL possesses antioxidant, anti-inflammatory, and cholinomimetic effects that might be beneficial for inflammatory bowel disease. Therefore, this study...

Proactive management strategies for potential gastrointestinal adverse reactions with ceritinib in patients with advanced ALK-positive non-small-cell lung cancer.

Cancer management and research

Schaefer ES, Baik C.
PMID: 27069372
Cancer Manag Res. 2016 Mar 24;8:33-8. doi: 10.2147/CMAR.S96471. eCollection 2016.

Anaplastic lymphoma kinase (ALK) gene fusions occur in 3%-7% of non-small-cell lung cancer (NSCLC) cases. Ceritinib, a once-daily, oral ALK inhibitor, has activity against crizotinib-resistant and crizotinib-naïve NSCLC, including brain metastases. Ceritinib (Zykadia™) was granted accelerated approval by the...

Current gut-directed therapies for irritable bowel syndrome.

Current treatment options in gastroenterology

Chang HY, Kelly EC, Lembo AJ.
PMID: 16836950
Curr Treat Options Gastroenterol. 2006 Jul;9(4):314-23. doi: 10.1007/s11938-006-0013-8.

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that can present with a wide array of symptoms that make treatment difficult. Current therapies are directed at relieving symptoms of abdominal pain or discomfort, bloating, constipation, and diarrhea. Pharmacologic...

Formulation and evaluation of hydroxypropylmethylcellulose-dicyclomine microsponges for colon targeted drug delivery: In vitro and in vivo evaluation.

Current drug delivery

Sher M, Sarfaraz RM, Iqbal S, Hussain MA, Naeem-Ul-Hassan M, Hassan F, Bukhari SNA.
PMID: 34353263
Curr Drug Deliv. 2021 Aug 05; doi: 10.2174/1567201818666210805153347. Epub 2021 Aug 05.

OBJECTIVE: The objective of present study was to design novel colon targeted delivery of dicyclomine Hydrochloride (DCH) microsponges.METHODS: Microsponges (MS1-MS4) based on different ratios of hydroxypropylmethylcellulose (HPMC) and DCH was prepared by quasi-emulsion solvent diffusion method. Micro-sponges were analyzed...

Efficacy and tolerability of fixed-dose combination of dexketoprofen and dicyclomine injection in acute renal colic.

Pain research and treatment

Porwal A, Mahajan AD, Oswal DS, Erram SS, Sheth DN, Balamurugan S, Kamat V, Enadle RP, Badadare A, Bhatnagar SK, Walvekar RS, Dhorepatil S, Naik RC, Basu I, Kshirsagar SN, Keny JV, Sengupta S.
PMID: 22577544
Pain Res Treat. 2012;2012:295926. doi: 10.1155/2012/295926. Epub 2012 Apr 23.

Objective. To evaluate the efficacy and tolerability of a fixed-dose combination of dexketoprofen and dicyclomine (DXD) injection in patients with acute renal colic. Patients and Methods. Two hundred and seventeen patients were randomized to receive either DXD (n =...

Showing 1 to 12 of 23 entries