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Showing 1 to 4 of 4 entries
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Striatal DAT availability does not change after supraphysiological glucose loading dose in humans.

Endocrine connections

Pak K, Seo S, Lee MJ, Kim K, Suh S, Im HJ, Kim IJ.
PMID: 34491899
Endocr Connect. 2021 Oct 07;10(10):1266-1272. doi: 10.1530/EC-21-0355.

Brain dopamine neurotransmission is regulated by the dopamine transporter (DAT), which drives reuptake of extracellular dopamine into the presynaptic neurons. We hypothesized that the glucose loading dose would affect the striatal DAT availability. An i.v. bolus injection of 18F-FP-CIT...

The association of DAT gene methylation with striatal DAT availability in healthy subjects.

EJNMMI research

Pak K, Seok JW, Nam HY, Seo S, Lee MJ, Kim K, Kim IJ.
PMID: 34120227
EJNMMI Res. 2021 Jun 12;11(1):58. doi: 10.1186/s13550-021-00800-y.

BACKGROUND: DNA methylation inhibits gene expression by preventing transcription factors from binding to DNA. Functioning of nigrostriatal dopaminergic neurons is influenced by the expression of the dopamine transporter (DAT), and genetic variations in the gene encoding DAT contribute to...

Classic Studies on the Interaction of Cocaine and the Dopamine Transporter.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Verma V.
PMID: 26598579
Clin Psychopharmacol Neurosci. 2015 Dec 31;13(3):227-38. doi: 10.9758/cpn.2015.13.3.227.

The dopamine transporter is responsible for recycling dopamine after release. Inhibitors of the dopamine transporter, such as cocaine, will stop the reuptake of dopamine and allow it to stay extracellularly, causing prominent changes at the molecular, cellular, and behavioral...

Hedonic Rating of Sucrose Is Sub-Regionally Associated with Striatal Dopamine Transporter in Humans.

Neuroendocrinology

Pak K, Seo S, Lee MJ, Kim K, Suh S, Lee J, Kim SJ, Kim IJ.
PMID: 34034262
Neuroendocrinology. 2021 May 25; doi: 10.1159/000517319. Epub 2021 May 25.

BACKGROUND: Eating behavior is determined by both homeostatic and hedonic values.OBJECTIVE: We investigated the association of hedonic value with striatal dopamine transporter (DAT) availability sub-regionally.METHOD: An intravenous bolus injection of 18F-FP-CIT was administered after the infusion of glucose or...

Showing 1 to 4 of 4 entries