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Showing 1 to 12 of 96 entries
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Exploring the Medical Aspects of Sport: One Man's Goal.

The Physician and sportsmedicine

Nash HL.
PMID: 27442945
Phys Sportsmed. 1986 May;14(5):204-19. doi: 10.1080/00913847.1986.11709082.

Whether it's a study on endorphins, catecholamines, altitude sickness, or thermal injury, John R. Sutton, MD, is sure to be in the thick of the research, quickly disseminating what he's learned, while applying the principles to himself. Teacher, researcher,...

Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome.

Sleep medicine

Walters AS.
PMID: 14592191
Sleep Med. 2002 Jul;3(4):301-4. doi: 10.1016/s1389-9457(02)00011-4.

BACKGROUND AND PURPOSE: Therapeutic studies of the opioids in restless legs syndrome (RLS) are reviewed.PATIENTS AND METHODS: Opioids appear to be a good short and long-term treatment for RLS as shown in open-label, double-blind and long-term follow-up studies. However,...

Treadmill exercise reduces self-administration of morphine in male rats.

Pathophysiology : the official journal of the International Society for Pathophysiology

Hosseini M, Alaei HA, Naderi A, Sharifi MR, Zahed R.
PMID: 19131225
Pathophysiology. 2009 Jun;16(1):3-7. doi: 10.1016/j.pathophys.2008.11.001. Epub 2009 Jan 07.

Exercise can activate the same pathways as morphine. The aim of the present study was to clarify the effect of short-term and mid-term exercises on the self-administration of morphine in rats. Male Wistar rats were initially trained to receive...

Effects of pentobarbital on proopiomelanocortin opioid products of neonatal piglets during normoxia and hypoxia.

Journal of neuroendocrinology

Moss IR, Inman JD.
PMID: 19215492
J Neuroendocrinol. 1991 Aug 01;3(4):455-60. doi: 10.1111/j.1365-2826.1991.tb00303.x.

Abstract Endogenous opioids have been shown to suppress physiological functions in the neonate. It has been suggested that anesthesia with barbiturates might enhance this suppression by influencing opioid systems directly. To explore this possibility, naive piglets, 2.2+/-0.8 (X+/-SD) days...

Cardiovascular Responses to Tonic Pain in REM Sleep-Deprived Rats: Role of Melatonin and Beta Endorphin.

Sultan Qaboos University medical journal

Kassab S, Sachdeva U, Das N, Al-Shaibani T, Nayar U.
PMID: 21748128
Sultan Qaboos Univ Med J. 2006 Jun;6(1):51-6.

OBJECTIVE: Chronic pain is associated with increased incidence of hypertension. Sleep deprivation, common in patients with chronic pain, is associated with increased blood pressure and heart rate. This study was designed to determine whether sleep deprivation induces increased cardiovascular...

Effects of chronic treatment of rats with dopamine receptor drugs on the post-translational processing of Beta-endorphin in the neurointermediate lobe of the pituitary gland.

Journal of neuroendocrinology

Sweep CG, Wiegant VM.
PMID: 19215385
J Neuroendocrinol. 1990 Aug 01;2(4):531-7. doi: 10.1111/j.1365-2826.1990.tb00444.x.

Abstract To investigate whether chronic changes in the activity of proopiomelanocortin cells in the neurointermediate lobe (NIL) of the pituitary gland are associated with changes in the enzymatic processing of beta-endorphin (betaE), the effects of treatment of rats with...

Musical feedback during exercise machine workout enhances mood.

Frontiers in psychology

Fritz TH, Halfpaap J, Grahl S, Kirkland A, Villringer A.
PMID: 24368905
Front Psychol. 2013 Dec 10;4:921. doi: 10.3389/fpsyg.2013.00921. eCollection 2013.

Music making has a number of beneficial effects for motor tasks compared to passive music listening. Given that recent research suggests that high energy musical activities elevate positive affect more strongly than low energy musical activities, we here investigated...

Long-term remission of adenoid cystic tongue carcinoma with low dose naltrexone and vitamin D3--a case report.

Oral health and dental management

Khan A.
PMID: 25284545
Oral Health Dent Manag. 2014 Sep;13(3):721-4.

Naltrexone (ReVia®) is a long-acting oral pure opiate antagonist which is approved for the treatment of alcohol addiction as a 50mg per day tablet. The mechanism of action is complete opiate blockade, which removes the pleasure sensation derived from...

Endorphins and Exercise: A Puzzling Relationship.

The Physician and sportsmedicine

Moore M.
PMID: 29261083
Phys Sportsmed. 1982 Feb;10(2):111-114. doi: 10.1080/00913847.1982.11947169.

Increased blood levels of endorphins after exercise have been cited to explain everything from runners' high to reduced pain perception, but little is known about these recently isolated substances or their functions.

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential.

Frontiers in molecular neuroscience

Burtscher J, Schwarzer C.
PMID: 28824375
Front Mol Neurosci. 2017 Aug 07;10:245. doi: 10.3389/fnmol.2017.00245. eCollection 2017.

Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease. The high incidence of resistance to antiepileptic...

Opioid-induced biochemical alterations of the neuroendocrine axis.

Expert review of endocrinology & metabolism

Thosani S, Jimenez C.
PMID: 30780884
Expert Rev Endocrinol Metab. 2011 Sep;6(5):705-713. doi: 10.1586/eem.11.55.

Exogenous opioids have been used for decades to palliate cancer-related pain and other cancer-related manifestations and, more recently, to treat patients with pain not related to oncologic disease. While the goal of opioid treatment is symptomatic relief and improved...

Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial.

ERJ open research

Currow DC, Hunt T, Louw S, Eckert D, Allcroft P, To THM, Greene A, Krajnik M, Mahler D, Ekström M.
PMID: 31886161
ERJ Open Res. 2019 Dec 23;5(4). doi: 10.1183/23120541.00153-2019. eCollection 2019 Oct.

QUESTION ADDRESSED BY THE STUDY: Endogenous opioids (endorphins) have been reported to modulate exercise-induced breathlessness, but the relative contribution of peripheral opioid receptors has not been tested.MATERIALS PARTICIPANTS AND METHODS: This was a double-blind, randomised, three-arm, cross-over trial in...

Showing 1 to 12 of 96 entries