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[Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Gromova OA, Torshin IIu, Gogoleva IV.
PMID: 24781241
Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(3):43-50.

Cerebrolysin is the drug which contains peptides derived from the brain of a pig. It is used in neurological practice for recovery of stroke patients and treatment of dementia. Despite the evidence-basis and some experimental studies, the distinct mechanisms...

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Gromova OA, Torshin IIu, Gogoleva IV. Mekhanizmy neĭrotroficheskogo i neĭroprotektornogo deĭstviia preparata tserebrolizin pri ishemii golovnogo mozga. [Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia]. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(3):43-50
Gromova, O. A., Torshin, I. I. u., & Gogoleva, I. V. (2014). Mekhanizmy neĭrotroficheskogo i neĭroprotektornogo deĭstviia preparata tserebrolizin pri ishemii golovnogo mozga. [Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 114(3), 43-50.
Gromova, O A, et al. "Mekhanizmy neĭrotroficheskogo i neĭroprotektornogo deĭstviia preparata tserebrolizin pri ishemii golovnogo mozga." [Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 114,3 (2014): 43-50.
Gromova OA, Torshin IIu, Gogoleva IV. Mekhanizmy neĭrotroficheskogo i neĭroprotektornogo deĭstviia preparata tserebrolizin pri ishemii golovnogo mozga. [Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia]. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(3):43-50. Russian. PMID: 24781241.
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[Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.].

Schmerz (Berlin, Germany)

Jurna I, Baldauf J.
PMID: 18415396
Schmerz. 1993 Dec;7(4):314-21. doi: 10.1007/BF02529868.

Prolonged administration of morphine for the treatment of chronic pain causes constipation requiring the use of laxatives, which may result in electrolyte deficits. Morphine-induced constipation is due to the binding of the drug to opioid receptors in the gastrointestinal...

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Jurna I, Baldauf J. Retardiert freigesetztes Naloxon oral: Aufhebung der Obstipation durch orales Morphin ohne Beseitigung der Analgesie. [Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.]. Schmerz. 1993;7(4):314-21doi: 10.1007/BF02529868.
Jurna, I., & Baldauf, J. (1993). Retardiert freigesetztes Naloxon oral: Aufhebung der Obstipation durch orales Morphin ohne Beseitigung der Analgesie. [Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.]. Schmerz (Berlin, Germany), 7(4), 314-21. https://doi.org/10.1007/BF02529868
Jurna, I, and Baldauf, J. "Retardiert freigesetztes Naloxon oral: Aufhebung der Obstipation durch orales Morphin ohne Beseitigung der Analgesie." [Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.]. Schmerz (Berlin, Germany) vol. 7,4 (1993): 314-21. doi: https://doi.org/10.1007/BF02529868
Jurna I, Baldauf J. Retardiert freigesetztes Naloxon oral: Aufhebung der Obstipation durch orales Morphin ohne Beseitigung der Analgesie. [Oral administration of slow-release naloxone for prevention of constipation but not analgesia following oral morphine.]. Schmerz. 1993 Dec;7(4):314-21. doi: 10.1007/BF02529868. German. PMID: 18415396.
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Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome.

Sleep medicine

Walters AS.
PMID: 14592191
Sleep Med. 2002 Jul;3(4):301-4. doi: 10.1016/s1389-9457(02)00011-4.

BACKGROUND AND PURPOSE: Therapeutic studies of the opioids in restless legs syndrome (RLS) are reviewed.PATIENTS AND METHODS: Opioids appear to be a good short and long-term treatment for RLS as shown in open-label, double-blind and long-term follow-up studies. However,...

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Walters AS. Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome. Sleep Med. 2002;3(4):301-4doi: 10.1016/s1389-9457(02)00011-4.
Walters, A. S. (2002). Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome. Sleep medicine, 3(4), 301-4. https://doi.org/10.1016/s1389-9457(02)00011-4
Walters, Arthur S. "Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome." Sleep medicine vol. 3,4 (2002): 301-4. doi: https://doi.org/10.1016/s1389-9457(02)00011-4
Walters AS. Review of receptor agonist and antagonist studies relevant to the opiate system in restless legs syndrome. Sleep Med. 2002 Jul;3(4):301-4. doi: 10.1016/s1389-9457(02)00011-4. PMID: 14592191.
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Small molecule mimetics of GHRP-6.

Expert opinion on investigational drugs

DeVita RJ.
PMID: 15989584
Expert Opin Investig Drugs. 1997 Dec;6(12):1839-43. doi: 10.1517/13543784.6.12.1839.

In 1981, Bowers reported that xenobiotic peptides, derived from the Leu- and Met- enkephalins, demonstrated novel growth hormone (GH) secretory activity. The most potent peptide reported, GH releasing peptide-6 (GHRP-6), was shown to release GH by a different pathway...

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DeVita RJ. Small molecule mimetics of GHRP-6. Expert Opin Investig Drugs. 1997;6(12):1839-43doi: 10.1517/13543784.6.12.1839.
DeVita, R. J. (1997). Small molecule mimetics of GHRP-6. Expert opinion on investigational drugs, 6(12), 1839-43. https://doi.org/10.1517/13543784.6.12.1839
DeVita, R J. "Small molecule mimetics of GHRP-6." Expert opinion on investigational drugs vol. 6,12 (1997): 1839-43. doi: https://doi.org/10.1517/13543784.6.12.1839
DeVita RJ. Small molecule mimetics of GHRP-6. Expert Opin Investig Drugs. 1997 Dec;6(12):1839-43. doi: 10.1517/13543784.6.12.1839. PMID: 15989584.
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Determination of Enkephalins in Rat Cerebrospinal Fluid with High-Performance Liquid Chromatography-Electrochemical Detection: Increased Concentrations During Lactation are Controlled by Sucking.

Journal of neuroendocrinology

Forsberg G, Bednar I, Qureshi GA, Eneroth P, Sodersten P.
PMID: 19215451
J Neuroendocrinol. 1991 Feb 01;3(1):79-83. doi: 10.1111/j.1365-2826.1991.tb00243.x.

Abstract Methionine- and leucine-enkephalin were measured in the cerebrospinal fluid of lactating rats by high-performance liquid chromatography and electrochemical detection. The concentration of both peptides was high while the rats were nursing their litter. The concentration of methionine-enkephalin decreased...

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Forsberg G, Bednar I, Qureshi GA, et al. Determination of Enkephalins in Rat Cerebrospinal Fluid with High-Performance Liquid Chromatography-Electrochemical Detection: Increased Concentrations During Lactation are Controlled by Sucking. J Neuroendocrinol. 1991;3(1):79-83doi: 10.1111/j.1365-2826.1991.tb00243.x.
Forsberg, G., Bednar, I., Qureshi, G. A., Eneroth, P., & Sodersten, P. (1991). Determination of Enkephalins in Rat Cerebrospinal Fluid with High-Performance Liquid Chromatography-Electrochemical Detection: Increased Concentrations During Lactation are Controlled by Sucking. Journal of neuroendocrinology, 3(1), 79-83. https://doi.org/10.1111/j.1365-2826.1991.tb00243.x
Forsberg, G, et al. "Determination of Enkephalins in Rat Cerebrospinal Fluid with High-Performance Liquid Chromatography-Electrochemical Detection: Increased Concentrations During Lactation are Controlled by Sucking." Journal of neuroendocrinology vol. 3,1 (1991): 79-83. doi: https://doi.org/10.1111/j.1365-2826.1991.tb00243.x
Forsberg G, Bednar I, Qureshi GA, Eneroth P, Sodersten P. Determination of Enkephalins in Rat Cerebrospinal Fluid with High-Performance Liquid Chromatography-Electrochemical Detection: Increased Concentrations During Lactation are Controlled by Sucking. J Neuroendocrinol. 1991 Feb 01;3(1):79-83. doi: 10.1111/j.1365-2826.1991.tb00243.x. PMID: 19215451.
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Design and evaluation of inhibitors of enkephalin degrading enzymes.

Neurochemistry international

Fournie-Zaluski MC.
PMID: 20501241
Neurochem Int. 1988;12(3):375-82. doi: 10.1016/0197-0186(88)90177-5.

The endogenous opioid peptides enkephalins are degraded in vitro by several metallopeptidases (aminopeptidases, enkephalinase, dipeptidylaminopeptidases). Selective and mixed inhibitors of these enzymes were obtained by a rational approach taking into account crystallographic data on Thermolysin, a bacterial enzyme, used...

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Fournie-Zaluski MC. Design and evaluation of inhibitors of enkephalin degrading enzymes. Neurochem Int. 1988;12(3):375-82doi: 10.1016/0197-0186(88)90177-5.
Fournie-Zaluski, M. C. (1988). Design and evaluation of inhibitors of enkephalin degrading enzymes. Neurochemistry international, 12(3), 375-82. https://doi.org/10.1016/0197-0186(88)90177-5
Fournie-Zaluski, M C. "Design and evaluation of inhibitors of enkephalin degrading enzymes." Neurochemistry international vol. 12,3 (1988): 375-82. doi: https://doi.org/10.1016/0197-0186(88)90177-5
Fournie-Zaluski MC. Design and evaluation of inhibitors of enkephalin degrading enzymes. Neurochem Int. 1988;12(3):375-82. doi: 10.1016/0197-0186(88)90177-5. PMID: 20501241.
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Physiology of the sphincter of Oddi--the present and the future?--Part 1.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Ballal MA, Sanford PA.
PMID: 19864708
Saudi J Gastroenterol. 2000 Sep;6(3):129-46.

The mechanisms controlling the sphincter of Oddi (SO) have received considerable attention over the past two decades. Progress towards their elucidation has been slow, perhaps because of the sphincter's relative inaccessibility and the different responses of the human "resistor"...

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Ballal MA, Sanford PA. Physiology of the sphincter of Oddi--the present and the future?--Part 1. Saudi J Gastroenterol. 2000;6(3):129-46
Ballal, M. A., & Sanford, P. A. (2000). Physiology of the sphincter of Oddi--the present and the future?--Part 1. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 6(3), 129-46.
Ballal, M A, and Sanford, P A. "Physiology of the sphincter of Oddi--the present and the future?--Part 1." Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association vol. 6,3 (2000): 129-46.
Ballal MA, Sanford PA. Physiology of the sphincter of Oddi--the present and the future?--Part 1. Saudi J Gastroenterol. 2000 Sep;6(3):129-46. PMID: 19864708.
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The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential.

Frontiers in molecular neuroscience

Burtscher J, Schwarzer C.
PMID: 28824375
Front Mol Neurosci. 2017 Aug 07;10:245. doi: 10.3389/fnmol.2017.00245. eCollection 2017.

Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease. The high incidence of resistance to antiepileptic...

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Burtscher J, Schwarzer C. The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential. Front Mol Neurosci. 2017;10:245doi: 10.3389/fnmol.2017.00245.
Burtscher, J., & Schwarzer, C. (2017). The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential. Frontiers in molecular neuroscience, 10245. https://doi.org/10.3389/fnmol.2017.00245
Burtscher, Johannes, and Schwarzer, Christoph. "The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential." Frontiers in molecular neuroscience vol. 10 (2017): 245. doi: https://doi.org/10.3389/fnmol.2017.00245
Burtscher J, Schwarzer C. The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential. Front Mol Neurosci. 2017 Aug 07;10:245. doi: 10.3389/fnmol.2017.00245. eCollection 2017. PMID: 28824375; PMCID: PMC5545604.
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Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes.

Experimental neurobiology

Nam MH, Han KS, Lee J, Bae JY, An H, Park S, Oh SJ, Kim E, Hwang E, Bae YC, Lee CJ.
PMID: 29731678
Exp Neurobiol. 2018 Apr;27(2):120-128. doi: 10.5607/en.2018.27.2.120. Epub 2018 Apr 24.

µ-opioid receptor (MOR) is a class of opioid receptors with a high affinity for enkephalins and beta-endorphin. In hippocampus, activation of MOR is known to enhance the neuronal excitability of pyramidal neurons, which has been mainly attributed to a...

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Nam MH, Han KS, Lee J, et al. Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes. Exp Neurobiol. 2018;27(2):120-128doi: 10.5607/en.2018.27.2.120.
Nam, M. H., Han, K. S., Lee, J., Bae, J. Y., An, H., Park, S., Oh, S. J., Kim, E., Hwang, E., Bae, Y. C., & Lee, C. J. (2018). Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes. Experimental neurobiology, 27(2), 120-128. https://doi.org/10.5607/en.2018.27.2.120
Nam, Min-Ho, et al. "Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes." Experimental neurobiology vol. 27,2 (2018): 120-128. doi: https://doi.org/10.5607/en.2018.27.2.120
Nam MH, Han KS, Lee J, Bae JY, An H, Park S, Oh SJ, Kim E, Hwang E, Bae YC, Lee CJ. Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes. Exp Neurobiol. 2018 Apr;27(2):120-128. doi: 10.5607/en.2018.27.2.120. Epub 2018 Apr 24. PMID: 29731678; PMCID: PMC5934543.
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Endogenous opiates and behavior: 2019.

Peptides

Bodnar RJ.
PMID: 33831447
Peptides. 2021 Jul;141:170547. doi: 10.1016/j.peptides.2021.170547. Epub 2021 Apr 05.

This paper is the forty-second consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2019 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and...

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Bodnar RJ. Endogenous opiates and behavior: 2019. Peptides. 2021;141:170547doi: 10.1016/j.peptides.2021.170547.
Bodnar, R. J. (2021). Endogenous opiates and behavior: 2019. Peptides, 141170547. https://doi.org/10.1016/j.peptides.2021.170547
Bodnar, Richard J. "Endogenous opiates and behavior: 2019." Peptides vol. 141 (2021): 170547. doi: https://doi.org/10.1016/j.peptides.2021.170547
Bodnar RJ. Endogenous opiates and behavior: 2019. Peptides. 2021 Jul;141:170547. doi: 10.1016/j.peptides.2021.170547. Epub 2021 Apr 05. PMID: 33831447.
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Taste Buds and Neuromasts of Astyanax jordani: Distribution and Immunochemical Demonstration of Co-localized Substance P and Enkephalins.

The European journal of neuroscience

Bensouilah M, Denizot JP.
PMID: 12106180
Eur J Neurosci. 1991;3(5):407-414. doi: 10.1111/j.1460-9568.1991.tb00828.x.

The distribution and some immunohistochemical aspects of the taste buds and free neuromasts of the blind cave fish Astyanax jordani were investigated using serial sections of whole fish. Taste buds are restricted to the skin of the lips and...

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Bensouilah M, Denizot JP. Taste Buds and Neuromasts of Astyanax jordani: Distribution and Immunochemical Demonstration of Co-localized Substance P and Enkephalins. Eur J Neurosci. 1991;3(5):407-414doi: 10.1111/j.1460-9568.1991.tb00828.x.
Bensouilah, M., & Denizot, J. P. (1991). Taste Buds and Neuromasts of Astyanax jordani: Distribution and Immunochemical Demonstration of Co-localized Substance P and Enkephalins. The European journal of neuroscience, 3(5), 407-414. https://doi.org/10.1111/j.1460-9568.1991.tb00828.x
Bensouilah, M., and Denizot, J.-P.. "Taste Buds and Neuromasts of Astyanax jordani: Distribution and Immunochemical Demonstration of Co-localized Substance P and Enkephalins." The European journal of neuroscience vol. 3,5 (1991): 407-414. doi: https://doi.org/10.1111/j.1460-9568.1991.tb00828.x
Bensouilah M, Denizot JP. Taste Buds and Neuromasts of Astyanax jordani: Distribution and Immunochemical Demonstration of Co-localized Substance P and Enkephalins. Eur J Neurosci. 1991;3(5):407-414. doi: 10.1111/j.1460-9568.1991.tb00828.x. PMID: 12106180.
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Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs.

The European journal of neuroscience

Safieddine S, Eybalin M.
PMID: 12106433
Eur J Neurosci. 1992;4(10):981-992. doi: 10.1111/j.1460-9568.1992.tb00124.x.

The efferent (olivocochlear) nerve supply to the cochlea is subdivided into a lateral and a medial innervation according to several criteria, e.g. locus of origin in the superior olivary complex and type of synaptic connections established in the organ...

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Safieddine S, Eybalin M. Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs. Eur J Neurosci. 1992;4(10):981-992doi: 10.1111/j.1460-9568.1992.tb00124.x.
Safieddine, S., & Eybalin, M. (1992). Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs. The European journal of neuroscience, 4(10), 981-992. https://doi.org/10.1111/j.1460-9568.1992.tb00124.x
Safieddine, Saaid, and Eybalin, Michel. "Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs." The European journal of neuroscience vol. 4,10 (1992): 981-992. doi: https://doi.org/10.1111/j.1460-9568.1992.tb00124.x
Safieddine S, Eybalin M. Triple Immunofluorescence Evidence for the Coexistence of Acetylcholine, Enkephalins and Calcitonin Gene-related Peptide Within Efferent (Olivocochlear) Neurons of Rats and Guinea-pigs. Eur J Neurosci. 1992;4(10):981-992. doi: 10.1111/j.1460-9568.1992.tb00124.x. PMID: 12106433.
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