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Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration.

The AAPS journal

Bussing D, Li Z, Li Y, Chang HP, Chang HY, Guo L, Verma A, Shah DK.
PMID: 34750690
AAPS J. 2021 Nov 08;23(6):116. doi: 10.1208/s12248-021-00647-0.

The ocular pharmacokinetics (PK) of antibody-based therapies are infrequently studied in mice due to the technical difficulties in working with the small murine eye. This study is the first of its kind to quantitatively measure the PK of variously...

Cite
Bussing D, Li Z, Li Y, et al. Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration. AAPS J. 2021;23(6):116doi: 10.1208/s12248-021-00647-0.
Bussing, D., Li, Z., Li, Y., Chang, H. P., Chang, H. Y., Guo, L., Verma, A., & Shah, D. K. (2021). Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration. The AAPS journal, 23(6), 116. https://doi.org/10.1208/s12248-021-00647-0
Bussing, David, et al. "Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration." The AAPS journal vol. 23,6 (2021): 116. doi: https://doi.org/10.1208/s12248-021-00647-0
Bussing D, Li Z, Li Y, Chang HP, Chang HY, Guo L, Verma A, Shah DK. Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration. AAPS J. 2021 Nov 08;23(6):116. doi: 10.1208/s12248-021-00647-0. PMID: 34750690; PMCID: PMC8575492.
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