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Biological activities of fibroblast growth factor-2 in the adult myocardium

adult

Sheikh F, Kardami E.
GSID: azJtogwBBtsJ
KA Detillieux, F Sheikh, E Kardami… - Cardiovascular …, 2003 - academic.oup.com

… to support a passive mechanism of FGF-2 release from adult cardiac myocytes on a beat-to-beat … The diverse functions of FGF-2 in the adult myocardium can be divided into two basic …

Analysis of the function of microRNA-375 in humans using bioinformatics.

Biomedical reports

Chen X, Li B, Luo R, Cai S, Zhang C, Cao X.
PMID: 28515914
Biomed Rep. 2017 May;6(5):561-566. doi: 10.3892/br.2017.889. Epub 2017 Apr 10.

MicroRNA-375 (miR-375) is expressed at low levels in many types of solid tumor, particularly in gastrointestinal tumors. It is considered to be important in the development of cancer and certain diseases. Thus, more detailed knowledge is required on the...

EGFR Amplification and Glioblastoma Stem-Like Cells.

Stem cells international

Liffers K, Lamszus K, Schulte A.
PMID: 26136784
Stem Cells Int. 2015;2015:427518. doi: 10.1155/2015/427518. Epub 2015 Jun 02.

Glioblastoma (GBM), the most common malignant brain tumor in adults, contains a subpopulation of cells with a stem-like phenotype (GS-cells). GS-cells can be maintained in vitro using serum-free medium supplemented with epidermal growth factor, basic fibroblast growth factor-2, and...

The -553 T/A polymorphism in the promoter region of the FGF2 gene is associated with increased breast cancer risk in Polish women.

Archives of medical science : AMS

Rykala J, Przybylowska K, Majsterek I, Pasz-Walczak G, Sygut A, Dziki A, Kuna P.
PMID: 26170857
Arch Med Sci. 2015 Jun 19;11(3):619-27. doi: 10.5114/aoms.2013.35996. Epub 2014 Jan 23.

INTRODUCTION: Fibroblast growth factor-2 (FGF2) is an important signalling molecule contributing to angiogenesis, tumour growth and progression and its expression is implicated in breast cancer (BC) development. We investigated whether -553 T/A FGF2 gene polymorphism is associated with the...

Alteration of DNA damage signaling pathway profile in radiation-treated glioblastoma stem-like cells.

Oncology letters

Sun C, Wang Z, Song W, Chen B, Zhang J, Dai X, Wang L, Wu J, Lan Q, Huang Q, Dong J.
PMID: 26622748
Oncol Lett. 2015 Sep;10(3):1769-1774. doi: 10.3892/ol.2015.3411. Epub 2015 Jun 22.

The present study aimed to investigate the alteration of the DNA damage signaling pathway profile in radiation-treated glioblastoma stem-like cells (GSLCs), and also aimed to explore potential targets for overcoming glioblastoma radioresistance. Serum-free medium was used to isolate and...

Therapeutic angiogenesis induced by human umbilical cord tissue-derived mesenchymal stromal cells in a murine model of hindlimb ischemia.

Stem cell research & therapy

Pereira AR, Mendes TF, Ministro A, Teixeira M, Filipe M, Santos JM, Bárcia RN, Goyri-O'Neill J, Pinto F, Cruz PE, Cruz HJ, Santos SC.
PMID: 27680210
Stem Cell Res Ther. 2016 Sep 29;7(1):145. doi: 10.1186/s13287-016-0410-4.

BACKGROUND: Mesenchymal stem cells derived from human umbilical cord tissue, termed UCX®, have the potential to promote a full range of events leading to tissue regeneration and homeostasis. The main goal of this work was to investigate UCX® action...

siRNA targeting YAP gene inhibits gastric carcinoma growth and tumor metastasis in SCID mice.

Oncology letters

Zhou Z, Zhu JS, Gao CP, Li LP, Zhou C, Wang H, Liu XG.
PMID: 27073556
Oncol Lett. 2016 Apr;11(4):2806-2814. doi: 10.3892/ol.2016.4319. Epub 2016 Mar 09.

Yes-associated protein (YAP) is constitutively activated in numerous types of cancer, including gastric carcinoma. The aim of the present study was to investigate the effects of YAP silencing on proliferation, apoptosis, metastasis and angiogenesis in a gastric orthotopic implantation...

Mouse embryonic dorsal root ganglia contain pluripotent stem cells that show features similar to embryonic stem cells and induced pluripotent stem cells.

Biology open

Ogawa R, Fujita K, Ito K.
PMID: 28373172
Biol Open. 2017 May 15;6(5):602-618. doi: 10.1242/bio.021758.

In the present study, we showed that the dorsal root ganglion (DRG) in the mouse embryo contains pluripotent stem cells (PSCs) that have developmental capacities equivalent to those of embryonic stem (ES) cells and induced pluripotent stem cells. Mouse...

Calculating the mean time to capture for tethered ligands and its effect on the chemical equilibrium of bound ligand pairs.

Data in brief

Shen L, Decker CG, Maynard HD, Levine AJ.
PMID: 27408925
Data Brief. 2016 May 28;8:506-15. doi: 10.1016/j.dib.2016.05.050. eCollection 2016 Sep.

We present here the calculation of the mean time to capture of a tethered ligand to the receptor. This calculation is then used to determine the shift in the partitioning between (1) free, (2) singly bound, and (3) doubly...

Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth.

Clinical, cosmetic and investigational dermatology

Takabayashi Y, Nambu M, Ishihara M, Kuwabara M, Fukuda K, Nakamura S, Hattori H, Kiyosawa T.
PMID: 27274299
Clin Cosmet Investig Dermatol. 2016 May 17;9:127-34. doi: 10.2147/CCID.S108187. eCollection 2016.

PURPOSE: Although treatments for alopecia are in high demand, not all treatments are safe and reliable. Dalteparin/protamine nanoparticles (D/P NPs) can effectively carry growth factors (GFs) such as fibroblast GF (FGF)-2. The purpose of this study was to identify...

Effect of variation of FGF2 genotypes on the risk of osteosarcoma susceptibly: a case control study.

International journal of clinical and experimental medicine

Wang J, Liu H, Liu X, Qi X.
PMID: 26131213
Int J Clin Exp Med. 2015 Apr 15;8(4):6114-8. eCollection 2015.

OBJECTIVE: Genetic factors play an important role in osteosarcoma (OS) etiology and fibroblast growth factor 2 (FGF2) gene single polymorphisms may be involved. The aim of this study was to test whether FGF2 variants are associated with susceptibility to...

Absence of hair cell protection by exogenous FGF-1 and FGF-2 delivered to guinea pig cochlea in vivo.

Noise & health

Yamasoba T, Altschuler RA, Raphael Y, Miller AL, Shoji F, Miller JM.
PMID: 12689449
Noise Health. 2001;3(11):65-78.

Recent findings that glial cell line-derived neurotrophic factor (GDNF), neurotrophin-3 (NT-3), and transforming growth factor a can protect the auditory hair cells from acoustic trauma or aminoglycoside ototoxicity in vivo raise the question of whether other neurotrophic factors can...

Showing 1 to 12 of 360 entries