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Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine.

European journal of clinical pharmacology

Jhang KM, Huang JY, Nfor ON, Tung YC, Ku WY, Lee CT, Liaw YP.
PMID: 28567501
Eur J Clin Pharmacol. 2017 Jul;73(7):917. doi: 10.1007/s00228-017-2268-5.

No abstract available.

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Jhang KM, Huang JY, Nfor ON, et al. Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine. Eur J Clin Pharmacol. 2017;73(7):917doi: 10.1007/s00228-017-2268-5.
Jhang, K. M., Huang, J. Y., Nfor, O. N., Tung, Y. C., Ku, W. Y., Lee, C. T., & Liaw, Y. P. (2017). Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine. European journal of clinical pharmacology, 73(7), 917. https://doi.org/10.1007/s00228-017-2268-5
Jhang, Kai-Ming, et al. "Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine." European journal of clinical pharmacology vol. 73,7 (2017): 917. doi: https://doi.org/10.1007/s00228-017-2268-5
Jhang KM, Huang JY, Nfor ON, Tung YC, Ku WY, Lee CT, Liaw YP. Erratum to: Extrapyramidal symptoms after exposure to calcium channel blocker-flunarizine or cinnarizine. Eur J Clin Pharmacol. 2017 Jul;73(7):917. doi: 10.1007/s00228-017-2268-5. PMID: 28567501; PMCID: PMC6828116.
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Antidepressant-like activity of flunarizine in modified tail suspension test in rats.

North American journal of medical sciences

Shinde V, Yegnanarayan R, Shah P, Gupta A, Pophale P.
PMID: 25839001
N Am J Med Sci. 2015 Mar;7(3):100-3. doi: 10.4103/1947-2714.153921.

BACKGROUND: Flunarizine, a Ca(2+) channel blocker, crosses blood brain barrier (BBB), antagonizes calcium influx and interferes with neurotransmitter system. Flunarizine 20 mg/kg exhibited significant antidepressant activity in our previous study using forced swim test (FST) in mice, which was...

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Shinde V, Yegnanarayan R, Shah P, et al. Antidepressant-like activity of flunarizine in modified tail suspension test in rats. N Am J Med Sci. 2015;7(3):100-3doi: 10.4103/1947-2714.153921.
Shinde, V., Yegnanarayan, R., Shah, P., Gupta, A., & Pophale, P. (2015). Antidepressant-like activity of flunarizine in modified tail suspension test in rats. North American journal of medical sciences, 7(3), 100-3. https://doi.org/10.4103/1947-2714.153921
Shinde, Vinod, et al. "Antidepressant-like activity of flunarizine in modified tail suspension test in rats." North American journal of medical sciences vol. 7,3 (2015): 100-3. doi: https://doi.org/10.4103/1947-2714.153921
Shinde V, Yegnanarayan R, Shah P, Gupta A, Pophale P. Antidepressant-like activity of flunarizine in modified tail suspension test in rats. N Am J Med Sci. 2015 Mar;7(3):100-3. doi: 10.4103/1947-2714.153921. PMID: 25839001; PMCID: PMC4382763.
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[In Process Citation].

Zentralblatt fur Gynakologie

Gross W, Schroder S, Schleussner E, Borner A, Seewald HJ.
PMID: 10399253
Zentralbl Gynakol. 1999;121(6):269-73.

OBJECTIVE: We examined the placental transfer of the calcium antagonists Flunarizine and Verapamil and their effects on the placental metabolism using the dual in vitro perfusion of the human placental lobulus. MATERIAL AND METHODS: Eight placental lobuli were perfused...

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Gross W, Schroder S, Schleussner E, et al. Transplazentarer Transport und Gewebeaufnahme der Kalziumantagonisten Verapamil und Flunarizin in dem in vitro perfundierten menschlichen Plazentalobulus. [In Process Citation]. Zentralbl Gynakol. 1999;121(6):269-73
Gross, W., Schroder, S., Schleussner, E., Borner, A., & Seewald, H. J. (1999). Transplazentarer Transport und Gewebeaufnahme der Kalziumantagonisten Verapamil und Flunarizin in dem in vitro perfundierten menschlichen Plazentalobulus. [In Process Citation]. Zentralblatt fur Gynakologie, 121(6), 269-73.
Gross, et al. "Transplazentarer Transport und Gewebeaufnahme der Kalziumantagonisten Verapamil und Flunarizin in dem in vitro perfundierten menschlichen Plazentalobulus." [In Process Citation]. Zentralblatt fur Gynakologie vol. 121,6 (1999): 269-73.
Gross W, Schroder S, Schleussner E, Borner A, Seewald HJ. Transplazentarer Transport und Gewebeaufnahme der Kalziumantagonisten Verapamil und Flunarizin in dem in vitro perfundierten menschlichen Plazentalobulus. [In Process Citation]. Zentralbl Gynakol. 1999;121(6):269-73. German. PMID: 10399253.
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The potency of migraine prophylaxis with nilvadipine: eight cases reported with further consideration.

Pathophysiology : the official journal of the International Society for Pathophysiology

Kihara M, Takahashi M.
PMID: 11720809
Pathophysiology. 2001 Dec;8(2):129-131. doi: 10.1016/s0928-4680(01)00076-1.

Calcium antagonists are widely used in migraine prophylaxis. Flunarizine, a calcium antagonist is the most popular drug in prophylactic treatment of migraine in Japan, however, flunarizine is no longer sold in Japan. Therefore, we evaluated the effectiveness of the...

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Kihara M, Takahashi M. The potency of migraine prophylaxis with nilvadipine: eight cases reported with further consideration. Pathophysiology. 2001;8(2):129-131doi: 10.1016/s0928-4680(01)00076-1.
Kihara, M., & Takahashi, M. (2001). The potency of migraine prophylaxis with nilvadipine: eight cases reported with further consideration. Pathophysiology : the official journal of the International Society for Pathophysiology, 8(2), 129-131. https://doi.org/10.1016/s0928-4680(01)00076-1
Kihara, Mikihiro, and Takahashi, Mitsuo. "The potency of migraine prophylaxis with nilvadipine: eight cases reported with further consideration." Pathophysiology : the official journal of the International Society for Pathophysiology vol. 8,2 (2001): 129-131. doi: https://doi.org/10.1016/s0928-4680(01)00076-1
Kihara M, Takahashi M. The potency of migraine prophylaxis with nilvadipine: eight cases reported with further consideration. Pathophysiology. 2001 Dec;8(2):129-131. doi: 10.1016/s0928-4680(01)00076-1. PMID: 11720809.
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[Long-term efficacy and side effects of various migraine prophylactics: a retrospective analysis.].

Schmerz (Berlin, Germany)

Haag G, Mastrosimone F, Iaccarino C, Müller MJ.
PMID: 18415473
Schmerz. 1994 Sep;8(3):162-9. doi: 10.1007/BF02530393.

INTRODUCTION: Drug therapy for the prevention of migraine attacks is becoming more and attacks is becoming more and more important. The aims of such prophylactic treatment are to reach a lower frequency, shorter duration and milder intensity of migraine...

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Haag G, Mastrosimone F, Iaccarino C, et al. Langzeitwirksamkeit und Nebenwirkungen verschiedener Migräneprophylaktika-eine retrospektive Analyse. [Long-term efficacy and side effects of various migraine prophylactics: a retrospective analysis.]. Schmerz. 1994;8(3):162-9doi: 10.1007/BF02530393.
Haag, G., Mastrosimone, F., Iaccarino, C., & Müller, M. J. (1994). Langzeitwirksamkeit und Nebenwirkungen verschiedener Migräneprophylaktika-eine retrospektive Analyse. [Long-term efficacy and side effects of various migraine prophylactics: a retrospective analysis.]. Schmerz (Berlin, Germany), 8(3), 162-9. https://doi.org/10.1007/BF02530393
Haag, G, et al. "Langzeitwirksamkeit und Nebenwirkungen verschiedener Migräneprophylaktika-eine retrospektive Analyse." [Long-term efficacy and side effects of various migraine prophylactics: a retrospective analysis.]. Schmerz (Berlin, Germany) vol. 8,3 (1994): 162-9. doi: https://doi.org/10.1007/BF02530393
Haag G, Mastrosimone F, Iaccarino C, Müller MJ. Langzeitwirksamkeit und Nebenwirkungen verschiedener Migräneprophylaktika-eine retrospektive Analyse. [Long-term efficacy and side effects of various migraine prophylactics: a retrospective analysis.]. Schmerz. 1994 Sep;8(3):162-9. doi: 10.1007/BF02530393. German. PMID: 18415473.
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Determination of flunarizine in plasma by a new high-performance liquid chromatography method. Application to a bioavailability study in the rat.

Journal of pharmaceutical and biomedical analysis

Aparicio X, Gras J, Campos A, Fernandez E, Gelpí E.
PMID: 16867429
J Pharm Biomed Anal. 1988;6(2):167-73. doi: 10.1016/0731-7085(88)80042-6.

A reversed-phase high performance liquid chromatographic (HPLC) method is described for the study of the pharmacokinetics of flunarizine. The method involves selective liquid-solid extraction of flunarizine and meclizine (as internal standard) from samples of rat plasma. The optimization of...

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Aparicio X, Gras J, Campos A, et al. Determination of flunarizine in plasma by a new high-performance liquid chromatography method. Application to a bioavailability study in the rat. J Pharm Biomed Anal. 1988;6(2):167-73doi: 10.1016/0731-7085(88)80042-6.
Aparicio, X., Gras, J., Campos, A., Fernandez, E., & Gelpí, E. (1988). Determination of flunarizine in plasma by a new high-performance liquid chromatography method. Application to a bioavailability study in the rat. Journal of pharmaceutical and biomedical analysis, 6(2), 167-73. https://doi.org/10.1016/0731-7085(88)80042-6
Aparicio, X, et al. "Determination of flunarizine in plasma by a new high-performance liquid chromatography method. Application to a bioavailability study in the rat." Journal of pharmaceutical and biomedical analysis vol. 6,2 (1988): 167-73. doi: https://doi.org/10.1016/0731-7085(88)80042-6
Aparicio X, Gras J, Campos A, Fernandez E, Gelpí E. Determination of flunarizine in plasma by a new high-performance liquid chromatography method. Application to a bioavailability study in the rat. J Pharm Biomed Anal. 1988;6(2):167-73. doi: 10.1016/0731-7085(88)80042-6. PMID: 16867429.
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Optimization for detection of flunarizine by high performance liquid chromatography/electrospray/mass spectrometry.

Talanta

Fuh MR, Hsieh CJ, Tai YL.
PMID: 18967684
Talanta. 1999 Aug 09;49(5):1069-75. doi: 10.1016/s0039-9140(99)00072-7.

This paper describes a newly developed high performance liquid chromatography/electrospray/mass spectrometry (HPLC/ES/MS) method for the determination of flunarizine (FZ) in artificial cerebrospinal fluid. The optimization for the detection of FZ in biological fluid by LC/ES/MS was investigated. The effects...

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Fuh MR, Hsieh CJ, Tai YL. Optimization for detection of flunarizine by high performance liquid chromatography/electrospray/mass spectrometry. Talanta. 1999;49(5):1069-75doi: 10.1016/s0039-9140(99)00072-7.
Fuh, M. R., Hsieh, C. J., & Tai, Y. L. (1999). Optimization for detection of flunarizine by high performance liquid chromatography/electrospray/mass spectrometry. Talanta, 49(5), 1069-75. https://doi.org/10.1016/s0039-9140(99)00072-7
Fuh, M R, et al. "Optimization for detection of flunarizine by high performance liquid chromatography/electrospray/mass spectrometry." Talanta vol. 49,5 (1999): 1069-75. doi: https://doi.org/10.1016/s0039-9140(99)00072-7
Fuh MR, Hsieh CJ, Tai YL. Optimization for detection of flunarizine by high performance liquid chromatography/electrospray/mass spectrometry. Talanta. 1999 Aug 09;49(5):1069-75. doi: 10.1016/s0039-9140(99)00072-7. PMID: 18967684.
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Intracellular calcium changes induced by the endozepine triakontatetraneuropeptide in human polymorphonuclear leukocytes: role of protein kinase C and effect of calcium channel blockers.

Cell communication and signaling : CCS

Marino F, Cosentino M, Ferrari M, Cattaneo S, Frigo G, Fietta AM, Lecchini S, Frigo GM.
PMID: 15228623
Cell Commun Signal. 2004 Jun 30;2(1):6. doi: 10.1186/1478-811X-2-6.

BACKGROUND: The endozepine triakontatetraneuropeptide (TTN) induces intracellular calcium ([Ca++]i) changes followed by activation in human polymorphonuclear leukocytes (PMNs). The present study was undertaken to investigate the role of protein kinase (PK) C in the modulation of the response to...

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Marino F, Cosentino M, Ferrari M, et al. Intracellular calcium changes induced by the endozepine triakontatetraneuropeptide in human polymorphonuclear leukocytes: role of protein kinase C and effect of calcium channel blockers. Cell Commun Signal. 2004;2(1):6doi: 10.1186/1478-811X-2-6.
Marino, F., Cosentino, M., Ferrari, M., Cattaneo, S., Frigo, G., Fietta, A. M., Lecchini, S., & Frigo, G. M. (2004). Intracellular calcium changes induced by the endozepine triakontatetraneuropeptide in human polymorphonuclear leukocytes: role of protein kinase C and effect of calcium channel blockers. Cell communication and signaling : CCS, 2(1), 6. https://doi.org/10.1186/1478-811X-2-6
Marino, Franca, et al. "Intracellular calcium changes induced by the endozepine triakontatetraneuropeptide in human polymorphonuclear leukocytes: role of protein kinase C and effect of calcium channel blockers." Cell communication and signaling : CCS vol. 2,1 (2004): 6. doi: https://doi.org/10.1186/1478-811X-2-6
Marino F, Cosentino M, Ferrari M, Cattaneo S, Frigo G, Fietta AM, Lecchini S, Frigo GM. Intracellular calcium changes induced by the endozepine triakontatetraneuropeptide in human polymorphonuclear leukocytes: role of protein kinase C and effect of calcium channel blockers. Cell Commun Signal. 2004 Jun 30;2(1):6. doi: 10.1186/1478-811X-2-6. PMID: 15228623; PMCID: PMC449738.
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Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain.

Archives of gerontology and geriatrics

Asanuma M, Ogawa N, Haba K, Hirata H, Mori A.
PMID: 15374420
Arch Gerontol Geriatr. 1991 Nov-Dec;13(3):271-8. doi: 10.1016/0167-4943(91)90049-v.

The calcium (Ca) antagonist flunarizine hydrochloride (FNZ) has been reported to induce parkinsonism, especially in the elderly. The effects of FNZ on dopamine receptors in rat striatal membranes, especially in aged rats, were studied using radiolabeled receptor assay. Similar...

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Asanuma M, Ogawa N, Haba K, et al. Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain. Arch Gerontol Geriatr. 1991;13(3):271-8doi: 10.1016/0167-4943(91)90049-v.
Asanuma, M., Ogawa, N., Haba, K., Hirata, H., & Mori, A. (1991). Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain. Archives of gerontology and geriatrics, 13(3), 271-8. https://doi.org/10.1016/0167-4943(91)90049-v
Asanuma, M, et al. "Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain." Archives of gerontology and geriatrics vol. 13,3 (1991): 271-8. doi: https://doi.org/10.1016/0167-4943(91)90049-v
Asanuma M, Ogawa N, Haba K, Hirata H, Mori A. Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain. Arch Gerontol Geriatr. 1991 Nov-Dec;13(3):271-8. doi: 10.1016/0167-4943(91)90049-v. PMID: 15374420.
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Interactions of verapamil, D 600, flunarizine and nifedipine with cerebral histamine-receptors.

Neurochemistry international

Taylor JE, Defeudis FV.
PMID: 20493137
Neurochem Int. 1986;9(3):379-81. doi: 10.1016/0197-0186(86)90079-3.

Experiments conducted on membrane fractions of guinea-pig brain using ligand-binding techniques have shown that certain Ca(2+)-antagonists interact with histamine (H(1) or H(2)) receptors. Flunarizine (inhibition constant, K(i) ? 86 nM) was nearly as potent as diphenhydramine (K(i) ? 44...

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Taylor JE, Defeudis FV. Interactions of verapamil, D 600, flunarizine and nifedipine with cerebral histamine-receptors. Neurochem Int. 1986;9(3):379-81doi: 10.1016/0197-0186(86)90079-3.
Taylor, J. E., & Defeudis, F. V. (1986). Interactions of verapamil, D 600, flunarizine and nifedipine with cerebral histamine-receptors. Neurochemistry international, 9(3), 379-81. https://doi.org/10.1016/0197-0186(86)90079-3
Taylor, J E, and Defeudis, F V. "Interactions of verapamil, D 600, flunarizine and nifedipine with cerebral histamine-receptors." Neurochemistry international vol. 9,3 (1986): 379-81. doi: https://doi.org/10.1016/0197-0186(86)90079-3
Taylor JE, Defeudis FV. Interactions of verapamil, D 600, flunarizine and nifedipine with cerebral histamine-receptors. Neurochem Int. 1986;9(3):379-81. doi: 10.1016/0197-0186(86)90079-3. PMID: 20493137.
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Experimental re-evaluation of flunarizine as add-on antiepileptic therapy.

Journal of pharmacy & bioallied sciences

Thakur A, Sahai AK, Thakur JS.
PMID: 21687355
J Pharm Bioallied Sci. 2011 Apr;3(2):253-8. doi: 10.4103/0975-7406.80782.

BACKGROUND: Experimental studies have found several calcium channel blockers with anticonvulsant property. Flunarizine is one of the most potent calcium channel blockers, which has shown anticonvulsant effect against pentylenetetrazole (PTZ) and maximal electroshock (MES)-induced seizures. However, further experimental and...

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Thakur A, Sahai AK, Thakur JS. Experimental re-evaluation of flunarizine as add-on antiepileptic therapy. J Pharm Bioallied Sci. 2011;3(2):253-8doi: 10.4103/0975-7406.80782.
Thakur, A., Sahai, A. K., & Thakur, J. S. (2011). Experimental re-evaluation of flunarizine as add-on antiepileptic therapy. Journal of pharmacy & bioallied sciences, 3(2), 253-8. https://doi.org/10.4103/0975-7406.80782
Thakur, Anamika, et al. "Experimental re-evaluation of flunarizine as add-on antiepileptic therapy." Journal of pharmacy & bioallied sciences vol. 3,2 (2011): 253-8. doi: https://doi.org/10.4103/0975-7406.80782
Thakur A, Sahai AK, Thakur JS. Experimental re-evaluation of flunarizine as add-on antiepileptic therapy. J Pharm Bioallied Sci. 2011 Apr;3(2):253-8. doi: 10.4103/0975-7406.80782. PMID: 21687355; PMCID: PMC3103921.
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Long-term effect of a single dose of flunarizine in Huntington's disease.

European journal of neurology

Belfiore G, Campanella G, Cella S, De Michele G, Di Maio L, Filla A, Napolitano G.
PMID: 10210839
Eur J Neurol. 1998 May;5(3):249-253. doi: 10.1046/j.1468-1331.1998.530249.x.

We report a preliminary pilot study on the clinical efficacy of flunarizine (FNZ), a calcium-entry blocker that causes extrapyramidal side-effects, in 10 patients with Huntington's disease (HD). FNZ (20 mg) administered by the sublingual route resulted in a decrease...

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Belfiore G, Campanella G, Cella S, et al. Long-term effect of a single dose of flunarizine in Huntington's disease. Eur J Neurol. 1998;5(3):249-253doi: 10.1046/j.1468-1331.1998.530249.x.
Belfiore, G., Campanella, G., Cella, S., De Michele G, Di Maio L, Filla, A., & Napolitano, G. (1998). Long-term effect of a single dose of flunarizine in Huntington's disease. European journal of neurology, 5(3), 249-253. https://doi.org/10.1046/j.1468-1331.1998.530249.x
Belfiore, et al. "Long-term effect of a single dose of flunarizine in Huntington's disease." European journal of neurology vol. 5,3 (1998): 249-253. doi: https://doi.org/10.1046/j.1468-1331.1998.530249.x
Belfiore G, Campanella G, Cella S, De Michele G, Di Maio L, Filla A, Napolitano G. Long-term effect of a single dose of flunarizine in Huntington's disease. Eur J Neurol. 1998 May;5(3):249-253. doi: 10.1046/j.1468-1331.1998.530249.x. PMID: 10210839.
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Showing 1 to 12 of 79 entries