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Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay.

BMJ open

Guzman JD, Evangelopoulos D, Gupta A, Birchall K, Mwaigwisya S, Saxty B, McHugh TD, Gibbons S, Malkinson J, Bhakta S.
PMID: 23794563
BMJ Open. 2013 Jun 20;3(6). doi: 10.1136/bmjopen-2013-002672.

OBJECTIVES: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline. The aim of this study was to validate the use of the high-throughput spot culture growth inhibition (HT-SPOTi) assay...

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Guzman JD, Evangelopoulos D, Gupta A, et al. Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. BMJ Open. 2013;3(6)doi: 10.1136/bmjopen-2013-002672.
Guzman, J. D., Evangelopoulos, D., Gupta, A., Birchall, K., Mwaigwisya, S., Saxty, B., McHugh, T. D., Gibbons, S., Malkinson, J., & Bhakta, S. (2013). Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. BMJ open, 3(6), . https://doi.org/10.1136/bmjopen-2013-002672
Guzman, Juan D, et al. "Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay." BMJ open vol. 3,6 (2013). doi: https://doi.org/10.1136/bmjopen-2013-002672
Guzman JD, Evangelopoulos D, Gupta A, Birchall K, Mwaigwisya S, Saxty B, McHugh TD, Gibbons S, Malkinson J, Bhakta S. Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. BMJ Open. 2013 Jun 20;3(6). doi: 10.1136/bmjopen-2013-002672. PMID: 23794563; PMCID: PMC3693423.
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