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Showing 1 to 4 of 4 entries
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Transcriptome-wide association study reveals two genes that influence mismatch negativity.

Cell reports

Bhat A, Irizar H, Thygesen JH, Kuchenbaecker K, Pain O, Adams RA, Zartaloudi E, Harju-Seppänen J, Austin-Zimmerman I, Wang B, Muir R, Summerfelt A, Du XM, Bruce H, O'Donnell P, Srivastava DP, Friston K, Hong LE, Hall MH, Bramon E.
PMID: 33730571
Cell Rep. 2021 Mar 16;34(11):108868. doi: 10.1016/j.celrep.2021.108868.

Mismatch negativity (MMN) is a differential electrophysiological response measuring cortical adaptability to unpredictable stimuli. MMN is consistently attenuated in patients with psychosis. However, the genetics of MMN are uncharted, limiting the validation of MMN as a psychosis endophenotype. Here,...

The interplay between genetics, cognition and schizophrenia.

Brain : a journal of neurology

Calafato MS, Bramon E.
PMID: 30698760
Brain. 2019 Feb 01;142(2):236-238. doi: 10.1093/brain/awy345.

No abstract available.

What causes psychosis? An umbrella review of risk and protective factors.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Radua J, Ramella-Cravaro V, Ioannidis JPA, Reichenberg A, Phiphopthatsanee N, Amir T, Yenn Thoo H, Oliver D, Davies C, Morgan C, McGuire P, Murray RM, Fusar-Poli P.
PMID: 29352556
World Psychiatry. 2018 Feb;17(1):49-66. doi: 10.1002/wps.20490.

Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and protective factors have been suggested. This umbrella review aimed to classify the strength of evidence for the associations between each factor and psychotic disorders whilst controlling...

The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics.

Genes

Austin-Zimmerman I, Wronska M, Wang B, Irizar H, Thygesen JH, Bhat A, Denaxas S, Fatemifar G, Finan C, Harju-Seppänen J, Giannakopoulou O, Kuchenbaecker K, Zartaloudi E, McQuillin A, Bramon E.
PMID: 34828364
Genes (Basel). 2021 Nov 03;12(11). doi: 10.3390/genes12111758.

CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions. Antidepressants and antipsychotics have previously been associated with risk of diabetes. We examined whether...

Showing 1 to 4 of 4 entries