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A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030.

Journal of inflammation (London, England)

Palmqvist N, Siller M, Klint C, Sjödin A.
PMID: 27340371
J Inflamm (Lond). 2016 Jun 22;13:20. doi: 10.1186/s12950-016-0127-2. eCollection 2016.

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic eczematous lesions that are commonly treated with topical corticosteroids and calcineurin inhibitors. Side-effects and safety concerns associated with these agents restrict their use, and new,...

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Palmqvist N, Siller M, Klint C, et al. A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030. J Inflamm (Lond). 2016;13:20doi: 10.1186/s12950-016-0127-2.
Palmqvist, N., Siller, M., Klint, C., & Sjödin, A. (2016). A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030. Journal of inflammation (London, England), 1320. https://doi.org/10.1186/s12950-016-0127-2
Palmqvist, Niklas, et al. "A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030." Journal of inflammation (London, England) vol. 13 (2016): 20. doi: https://doi.org/10.1186/s12950-016-0127-2
Palmqvist N, Siller M, Klint C, Sjödin A. A human and animal model-based approach to investigating the anti-inflammatory profile and potential of the 5-HT2B receptor antagonist AM1030. J Inflamm (Lond). 2016 Jun 22;13:20. doi: 10.1186/s12950-016-0127-2. eCollection 2016. PMID: 27340371; PMCID: PMC4918035.
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Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley.

Phytopathology

Jaime-Garcia R, Trinidad-Correa R, Felix-Gastelum R, Orum TV, Wasmann CC, Nelson MR.
PMID: 18944419
Phytopathology. 2000 Nov;90(11):1188-95. doi: 10.1094/PHYTO.2000.90.11.1188.

ABSTRACT The temporal and spatial patterns of Phytophthora infestans population genetic structure were analyzed in the Del Fuerte Valley, Sinaloa, Mexico, during the crop seasons of 1994 to 1995, 1995 to 1996, and 1996 to 1997 by geographical information...

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Jaime-Garcia R, Trinidad-Correa R, Felix-Gastelum R, et al. Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley. Phytopathology. 2000;90(11):1188-95doi: 10.1094/PHYTO.2000.90.11.1188.
Jaime-Garcia, R., Trinidad-Correa, R., Felix-Gastelum, R., Orum, T. V., Wasmann, C. C., & Nelson, M. R. (2000). Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley. Phytopathology, 90(11), 1188-95. https://doi.org/10.1094/PHYTO.2000.90.11.1188
Jaime-Garcia, R, et al. "Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley." Phytopathology vol. 90,11 (2000): 1188-95. doi: https://doi.org/10.1094/PHYTO.2000.90.11.1188
Jaime-Garcia R, Trinidad-Correa R, Felix-Gastelum R, Orum TV, Wasmann CC, Nelson MR. Temporal and Spatial Patterns of Genetic Structure of Phytophthora infestans from Tomato and Potato in the Del Fuerte Valley. Phytopathology. 2000 Nov;90(11):1188-95. doi: 10.1094/PHYTO.2000.90.11.1188. PMID: 18944419.
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Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis.

Modern rheumatology

Hayashi T, Matsumoto I, Muraki Y, Takahashi R, Chino Y, Goto D, Ito S, Tsutsumi A, Sumida T.
PMID: 17029074
Mod Rheumatol. 2005;15(4):258-63. doi: 10.1007/s10165-005-0405-y.

Anti-glucose-6-phosphate isomerase (GPI) antibodies (Abs) are known to be arthritogenic in mice. These Abs are elevated in several forms of arthritic condition in humans, although their prevalence in rheumatoid arthritis (RA) patients is still in debate. Some RA patients...

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Hayashi T, Matsumoto I, Muraki Y, et al. Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis. Mod Rheumatol. 2005;15(4):258-63doi: 10.1007/s10165-005-0405-y.
Hayashi, T., Matsumoto, I., Muraki, Y., Takahashi, R., Chino, Y., Goto, D., Ito, S., Tsutsumi, A., & Sumida, T. (2005). Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis. Modern rheumatology, 15(4), 258-63. https://doi.org/10.1007/s10165-005-0405-y
Hayashi, Taichi, et al. "Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis." Modern rheumatology vol. 15,4 (2005): 258-63. doi: https://doi.org/10.1007/s10165-005-0405-y
Hayashi T, Matsumoto I, Muraki Y, Takahashi R, Chino Y, Goto D, Ito S, Tsutsumi A, Sumida T. Clinical characteristics of anti-glucose-6-phosphate isomerase antibody-positive Japanese patients with rheumatoid arthritis. Mod Rheumatol. 2005;15(4):258-63. doi: 10.1007/s10165-005-0405-y. PMID: 17029074.
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Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease.

PLoS neglected tropical diseases

Llewellyn MS, Lewis MD, Acosta N, Yeo M, Carrasco HJ, Segovia M, Vargas J, Torrico F, Miles MA, Gaunt MW.
PMID: 19721699
PLoS Negl Trop Dis. 2009 Sep 01;3(9):e510. doi: 10.1371/journal.pntd.0000510.

Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe. Molecular dating suggests that T....

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Llewellyn MS, Lewis MD, Acosta N, et al. Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. PLoS Negl Trop Dis. 2009;3(9):e510doi: 10.1371/journal.pntd.0000510.
Llewellyn, M. S., Lewis, M. D., Acosta, N., Yeo, M., Carrasco, H. J., Segovia, M., Vargas, J., Torrico, F., Miles, M. A., & Gaunt, M. W. (2009). Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. PLoS neglected tropical diseases, 3(9), e510. https://doi.org/10.1371/journal.pntd.0000510
Llewellyn, Martin S, et al. "Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease." PLoS neglected tropical diseases vol. 3,9 (2009): e510. doi: https://doi.org/10.1371/journal.pntd.0000510
Llewellyn MS, Lewis MD, Acosta N, Yeo M, Carrasco HJ, Segovia M, Vargas J, Torrico F, Miles MA, Gaunt MW. Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. PLoS Negl Trop Dis. 2009 Sep 01;3(9):e510. doi: 10.1371/journal.pntd.0000510. PMID: 19721699; PMCID: PMC2727949.
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Characterization of Phytophthora spp. Causing Outbreaks of Citrus Brown Rot in Florida.

Phytopathology

Graham JH, Timmer LW, Drouillard DL, Peever TL.
PMID: 18944946
Phytopathology. 1998 Jul;88(7):724-9. doi: 10.1094/PHYTO.1998.88.7.724.

ABSTRACT Epidemics of citrus brown rot from 1994 to 1997 in the south-central and east-coast citrus areas of Florida were characterized and the causal Phytophthora spp. identified. Two species of Phytophthora, P. palmivora and P. nicotianae, were consistently associated...

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Graham JH, Timmer LW, Drouillard DL, et al. Characterization of Phytophthora spp. Causing Outbreaks of Citrus Brown Rot in Florida. Phytopathology. 1998;88(7):724-9doi: 10.1094/PHYTO.1998.88.7.724.
Graham, J. H., Timmer, L. W., Drouillard, D. L., & Peever, T. L. (1998). Characterization of Phytophthora spp. Causing Outbreaks of Citrus Brown Rot in Florida. Phytopathology, 88(7), 724-9. https://doi.org/10.1094/PHYTO.1998.88.7.724
Graham, J H, et al. "Characterization of Phytophthora spp. Causing Outbreaks of Citrus Brown Rot in Florida." Phytopathology vol. 88,7 (1998): 724-9. doi: https://doi.org/10.1094/PHYTO.1998.88.7.724
Graham JH, Timmer LW, Drouillard DL, Peever TL. Characterization of Phytophthora spp. Causing Outbreaks of Citrus Brown Rot in Florida. Phytopathology. 1998 Jul;88(7):724-9. doi: 10.1094/PHYTO.1998.88.7.724. PMID: 18944946.
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Population Genetic Structure of Phytophthora infestans in Ecuador.

Phytopathology

Forbes GA, Escobar XC, Ayala CC, Revelo J, Ordoñez ME, Fry BA, Doucett K, Fry WE.
PMID: 18945115
Phytopathology. 1997 Apr;87(4):375-80. doi: 10.1094/PHYTO.1997.87.4.375.

ABSTRACT The population genetic structure of Phytophthora infestans in Ecuador was assessed from 101 isolates collected from 1990 to 1992 and 111 isolates collected in 1993. All isolates were analyzed for mating type and allozyme genotype. Both samples were...

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Forbes GA, Escobar XC, Ayala CC, et al. Population Genetic Structure of Phytophthora infestans in Ecuador. Phytopathology. 1997;87(4):375-80doi: 10.1094/PHYTO.1997.87.4.375.
Forbes, G. A., Escobar, X. C., Ayala, C. C., Revelo, J., Ordoñez, M. E., Fry, B. A., Doucett, K., & Fry, W. E. (1997). Population Genetic Structure of Phytophthora infestans in Ecuador. Phytopathology, 87(4), 375-80. https://doi.org/10.1094/PHYTO.1997.87.4.375
Forbes, G A, et al. "Population Genetic Structure of Phytophthora infestans in Ecuador." Phytopathology vol. 87,4 (1997): 375-80. doi: https://doi.org/10.1094/PHYTO.1997.87.4.375
Forbes GA, Escobar XC, Ayala CC, Revelo J, Ordoñez ME, Fry BA, Doucett K, Fry WE. Population Genetic Structure of Phytophthora infestans in Ecuador. Phytopathology. 1997 Apr;87(4):375-80. doi: 10.1094/PHYTO.1997.87.4.375. PMID: 18945115.
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Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry.

Immune network

Alam J, Kim YC, Choi Y.
PMID: 24605075
Immune Netw. 2014 Feb;14(1):7-13. doi: 10.4110/in.2014.14.1.7. Epub 2014 Feb 21.

Molecular mimicry is an attractive mechanism for triggering autoimmunity. In this review, we explore the potential role of evolutionary conserved bacterial proteins in the production of autoantibodies with focus on granulomatosis with polyangiitis (GPA) and rheumatoid arthritis (RA). Seven...

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Alam J, Kim YC, Choi Y. Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry. Immune Netw. 2014;14(1):7-13doi: 10.4110/in.2014.14.1.7.
Alam, J., Kim, Y. C., & Choi, Y. (2014). Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry. Immune network, 14(1), 7-13. https://doi.org/10.4110/in.2014.14.1.7
Alam, Jehan, et al. "Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry." Immune network vol. 14,1 (2014): 7-13. doi: https://doi.org/10.4110/in.2014.14.1.7
Alam J, Kim YC, Choi Y. Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry. Immune Netw. 2014 Feb;14(1):7-13. doi: 10.4110/in.2014.14.1.7. Epub 2014 Feb 21. PMID: 24605075; PMCID: PMC3942510.
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Natural Occurrence of Phytophthora infestans on Black Nightshade (Solanum nigrum) in Wales.

Plant disease

Deahl KL, Shaw DS, Cooke LR.
PMID: 30812497
Plant Dis. 2004 Jul;88(7):771. doi: 10.1094/PDIS.2004.88.7.771A.

There is only one published record of natural infection of black nightshade (Solanum nigrum L.) by Phytophthora infestans (Mont.) de Bary in England (3) and none from Wales. In August 2001, brown, necrotic leaf lesions with pale green margins...

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Deahl KL, Shaw DS, Cooke LR. Natural Occurrence of Phytophthora infestans on Black Nightshade (Solanum nigrum) in Wales. Plant Dis. 2004;88(7):771doi: 10.1094/PDIS.2004.88.7.771A.
Deahl, K. L., Shaw, D. S., & Cooke, L. R. (2004). Natural Occurrence of Phytophthora infestans on Black Nightshade (Solanum nigrum) in Wales. Plant disease, 88(7), 771. https://doi.org/10.1094/PDIS.2004.88.7.771A
Deahl, K L, et al. "Natural Occurrence of Phytophthora infestans on Black Nightshade (Solanum nigrum) in Wales." Plant disease vol. 88,7 (2004): 771. doi: https://doi.org/10.1094/PDIS.2004.88.7.771A
Deahl KL, Shaw DS, Cooke LR. Natural Occurrence of Phytophthora infestans on Black Nightshade (Solanum nigrum) in Wales. Plant Dis. 2004 Jul;88(7):771. doi: 10.1094/PDIS.2004.88.7.771A. PMID: 30812497.
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First Report of Haplotype I-b of Phytophthora infestans in Central Mexico.

Plant disease

Garay-Serrano E, Fernández-Pavía SP, Rodríguez-Alvarado G, Flier WG, Lozoya-Saldaña H, Rojas-Martínez RI, Goss EM, Grünwald NJ.
PMID: 30780417
Plant Dis. 2007 Jul;91(7):909. doi: 10.1094/PDIS-91-7-0909B.

Central Mexico is considered a center of genetic diversity for Phytophthora infestans on the basis of a range of genotypic and phenotypic characteristics (3). Surprisingly, while mitochondrial DNA (mtDNA) haplotypes I-a, II-a, and II-b have been reported from central...

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Garay-Serrano E, Fernández-Pavía SP, Rodríguez-Alvarado G, et al. First Report of Haplotype I-b of Phytophthora infestans in Central Mexico. Plant Dis. 2007;91(7):909doi: 10.1094/PDIS-91-7-0909B.
Garay-Serrano, E., Fernández-Pavía, S. P., Rodríguez-Alvarado, G., Flier, W. G., Lozoya-Saldaña, H., Rojas-Martínez, R. I., Goss, E. M., & Grünwald, N. J. (2007). First Report of Haplotype I-b of Phytophthora infestans in Central Mexico. Plant disease, 91(7), 909. https://doi.org/10.1094/PDIS-91-7-0909B
Garay-Serrano, E, et al. "First Report of Haplotype I-b of Phytophthora infestans in Central Mexico." Plant disease vol. 91,7 (2007): 909. doi: https://doi.org/10.1094/PDIS-91-7-0909B
Garay-Serrano E, Fernández-Pavía SP, Rodríguez-Alvarado G, Flier WG, Lozoya-Saldaña H, Rojas-Martínez RI, Goss EM, Grünwald NJ. First Report of Haplotype I-b of Phytophthora infestans in Central Mexico. Plant Dis. 2007 Jul;91(7):909. doi: 10.1094/PDIS-91-7-0909B. PMID: 30780417.
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Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease.

Frontiers in pharmacology

Zhang Y, Zhao H, Liu B, Li L, Zhang L, Bao M, Ji X, He X, Yi J, Chen P, Lu C, Lu A.
PMID: 32174839
Front Pharmacol. 2020 Feb 27;11:195. doi: 10.3389/fphar.2020.00195. eCollection 2020.

OBJECTIVE: Natural autoantibodies have been implicated to play a key role in the pathogenesis of coronary heart disease (CHD) because they augment autoimmune activation. The aim of this study was to identify novel specific autoantibodies of CHD, and analyze...

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Zhang Y, Zhao H, Liu B, et al. Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease. Front Pharmacol. 2020;11:195doi: 10.3389/fphar.2020.00195.
Zhang, Y., Zhao, H., Liu, B., Li, L., Zhang, L., Bao, M., Ji, X., He, X., Yi, J., Chen, P., Lu, C., & Lu, A. (2020). Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease. Frontiers in pharmacology, 11195. https://doi.org/10.3389/fphar.2020.00195
Zhang, Yin, et al. "Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease." Frontiers in pharmacology vol. 11 (2020): 195. doi: https://doi.org/10.3389/fphar.2020.00195
Zhang Y, Zhao H, Liu B, Li L, Zhang L, Bao M, Ji X, He X, Yi J, Chen P, Lu C, Lu A. Low Level Antibodies Against Alpha-Tropomyosin Are Associated With Increased Risk of Coronary Heart Disease. Front Pharmacol. 2020 Feb 27;11:195. doi: 10.3389/fphar.2020.00195. eCollection 2020. PMID: 32174839; PMCID: PMC7056748.
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Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis.

Frontiers in immunology

Leceta J, Garin MI, Conde C.
PMID: 34335612
Front Immunol. 2021 Jul 16;12:701862. doi: 10.3389/fimmu.2021.701862. eCollection 2021.

The K/BxN mouse model of rheumatoid arthritis (RA) closely resembles the human disease. In this model, arthritis results from activation of autoreactive KRN T cells recognizing the glycolytic enzyme glucose-6-phosphate isomerase (GPI) autoantigen, which provides help to GPI-specific B...

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Leceta J, Garin MI, Conde C. Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis. Front Immunol. 2021;12:701862doi: 10.3389/fimmu.2021.701862.
Leceta, J., Garin, M. I., & Conde, C. (2021). Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis. Frontiers in immunology, 12701862. https://doi.org/10.3389/fimmu.2021.701862
Leceta, Javier, et al. "Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis." Frontiers in immunology vol. 12 (2021): 701862. doi: https://doi.org/10.3389/fimmu.2021.701862
Leceta J, Garin MI, Conde C. Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis. Front Immunol. 2021 Jul 16;12:701862. doi: 10.3389/fimmu.2021.701862. eCollection 2021. PMID: 34335612; PMCID: PMC8322839.
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Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of .

Pathogens (Basel, Switzerland)

Tanida K, Balczun C, Hahn A, Veit A, Nickel B, Poppert S, Scheid PL, Hagen RM, Frickmann H, Loderstädt U, Tannich E.
PMID: 34209257
Pathogens. 2021 Jun 30;10(7). doi: 10.3390/pathogens10070826.

To perform PCR from serum for the diagnosis of visceral leishmaniasis is convenient and much less invasive than the examination of deeper compartments such as bone marrow. We compared three

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Tanida K, Balczun C, Hahn A, et al. Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of . Pathogens. 2021;10(7)doi: 10.3390/pathogens10070826.
Tanida, K., Balczun, C., Hahn, A., Veit, A., Nickel, B., Poppert, S., Scheid, P. L., Hagen, R. M., Frickmann, H., Loderstädt, U., & Tannich, E. (2021). Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of . Pathogens (Basel, Switzerland), 10(7), . https://doi.org/10.3390/pathogens10070826
Tanida, Konstantin, et al. "Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of ." Pathogens (Basel, Switzerland) vol. 10,7 (2021). doi: https://doi.org/10.3390/pathogens10070826
Tanida K, Balczun C, Hahn A, Veit A, Nickel B, Poppert S, Scheid PL, Hagen RM, Frickmann H, Loderstädt U, Tannich E. Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of . Pathogens. 2021 Jun 30;10(7). doi: 10.3390/pathogens10070826. PMID: 34209257; PMCID: PMC8308501.
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Showing 1 to 12 of 64 entries