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Showing 1 to 12 of 63 entries
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Diagnostic value of serum bile acid composition patterns and serum glycocholic acid levels in cholangiocarcinoma.

Oncology letters

Proungvitaya S, Sombattheera S, Boonsiri P, Limpaiboon T, Wongkham S, Wongkham C, Titapun A, Proungvitaya T.
PMID: 29085505
Oncol Lett. 2017 Oct;14(4):4943-4948. doi: 10.3892/ol.2017.6763. Epub 2017 Aug 17.

Cholangiocarcinoma (CCA) is a cancer of biliary epithelial cell origin, which is prevalent in northeastern Thailand. The majority of patients with CCA are diagnosed at the advanced-stage of the disease. Although the early detection and diagnosis of CCA is...

Glycocholic acid and butyrate synergistically increase vitamin D-induced calcium uptake in Caco-2 intestinal epithelial cell monolayers.

Bone reports

Casselbrant A, Fändriks L, Wallenius V.
PMID: 32715032
Bone Rep. 2020 Jul 03;13:100294. doi: 10.1016/j.bonr.2020.100294. eCollection 2020 Dec.

BACKGROUND: Roux-en-Y gastric bypass (RYGB) substantially decreases intestinal calcium absorption and may eventually lead to bone resorption. This is likely a consequence of bile diversion from the alimentary limb, as the presence of bile seems necessary for vitamin D-mediated...

Why is glycocholic acid sodium salt better than deoxycholic acid sodium salt for the preparation of mixed micelle injections?.

Food science & nutrition

Wang T, Shen L, Sun L, Zhang Y, Li H, Wang Y, Quan D.
PMID: 31763016
Food Sci Nutr. 2019 Sep 27;7(11):3675-3680. doi: 10.1002/fsn3.1224. eCollection 2019 Nov.

Classical mixed micelle systems make excellent parenteral drug carriers for lipophilic or poorly soluble drugs, but many formulations details are not fully understood and need further study. Thus, we constructed mixed micelle systems with lecithin and either glycocholic acid...

Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats.

International journal of molecular sciences

Kim KH, Lee KA.
PMID: 35008991
Int J Mol Sci. 2022 Jan 05;23(1). doi: 10.3390/ijms23010566.

Aging is a degenerative process involving cell function deterioration, leading to altered metabolic pathways, increased metabolite diversity, and dysregulated metabolism. Previously, we reported that human placenta-derived mesenchymal stem cells (hPD-MSCs) have therapeutic effects on ovarian aging. This study aimed...

NMN Maintains Intestinal Homeostasis by Regulating the Gut Microbiota.

Frontiers in nutrition

Huang P, Jiang A, Wang X, Zhou Y, Tang W, Ren C, Qian X, Zhou Z, Gong A.
PMID: 34395502
Front Nutr. 2021 Jul 29;8:714604. doi: 10.3389/fnut.2021.714604. eCollection 2021.

The aim of this study was to determine the effects of long-term Nicotinamide mononucleotide (NMN) treatment on modulating gut microbiota diversity and composition, as well as its association with intestinal barrier function. In this study, C57BL/6J mice were fed...

Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.

Journal of bioscience and bioengineering

Pei Y, Cheng F, Li W, Yu Q, Ma C, Zou Y, Xu T, Liu S, Zhang S, Wang Q.
PMID: 34887181
J Biosci Bioeng. 2021 Dec 06; doi: 10.1016/j.jbiosc.2021.11.003. Epub 2021 Dec 06.

As a kind of animal medicine, cattle bile has anti-inflammatory, antipyretic and cholagogic effects. The fermentation process of cattle bile is included in the application of many traditional Chinese medicines. In this study, we fermented cattle bile singly and...

ATR FTIR Study of the Interaction of TiO.

Langmuir : the ACS journal of surfaces and colloids

Benbow NL, Rozenberga L, McQuillan AJ, Krasowska M, Beattie DA.
PMID: 34731567
Langmuir. 2021 Nov 16;37(45):13278-13290. doi: 10.1021/acs.langmuir.1c01830. Epub 2021 Nov 03.

The technique of in situ particle film attenuated total reflection Fourier transform infrared spectroscopy (ATR FTIR) has been used to probe the adsorption and coadsorption (sequential) of a common food protein (β-lactoglobulin, BLG) and two representative bile salts (taurocholic...

Toxicity of Pb continuous and pulse exposure on intestinal anatomy, bacterial diversity, and metabolites of Pelophylax nigromaculatus in pre-hibernation.

Chemosphere

Huang M, Liu Y, Dong W, Zhao Q, Duan R, Cao X, Wan Y, Yin J, Yi M.
PMID: 34919911
Chemosphere. 2021 Dec 14;290:133304. doi: 10.1016/j.chemosphere.2021.133304. Epub 2021 Dec 14.

Amphibians are often exposed to pulse pollution due to fluctuational inputs of pollutants in water. Traditional ecotoxicology research is mainly performed under constant exposure conditions, which is not consistent with the true environmental pollution. Frogs are sensitive to changes...

A clinical metabolomics-based biomarker signature as an approach for early diagnosis of gastric cardia adenocarcinoma.

Oncology letters

Sun Y, Li S, Li J, Xiao X, Hua Z, Wang X, Yan S.
PMID: 31897184
Oncol Lett. 2020 Jan;19(1):681-690. doi: 10.3892/ol.2019.11173. Epub 2019 Dec 02.

Gastric cardia adenocarcinoma (GCA) has a high mortality rate worldwide; however, current early diagnostic methods lack efficacy. Therefore, the aim of the present study was to identify potential biomarkers for the early diagnosis of GCA. Global metabolic profiles were...

Targeted Metabolomics Analysis of Bile Acids in Patients with Idiosyncratic Drug-Induced Liver Injury.

Metabolites

Xie Z, Zhang L, Chen E, Lu J, Xiao L, Liu Q, Zhu D, Zhang F, Xu X, Li L.
PMID: 34940610
Metabolites. 2021 Dec 08;11(12). doi: 10.3390/metabo11120852.

Drug-induced liver injury (DILI) is rare but clinically important due to a high rate of mortality. However, specific biomarkers for diagnosing and predicting the severity and prognosis of DILI are lacking. Here, we used targeted metabolomics to identify and...

Toxicity of Pb continuous and pulse exposure on intestinal anatomy, bacterial diversity, and metabolites of Pelophylax nigromaculatus in pre-hibernation.

Chemosphere

Huang M, Liu Y, Dong W, Zhao Q, Duan R, Cao X, Wan Y, Yin J, Yi M.
PMID: 34919911
Chemosphere. 2021 Dec 14;290:133304. doi: 10.1016/j.chemosphere.2021.133304. Epub 2021 Dec 14.

Amphibians are often exposed to pulse pollution due to fluctuational inputs of pollutants in water. Traditional ecotoxicology research is mainly performed under constant exposure conditions, which is not consistent with the true environmental pollution. Frogs are sensitive to changes...

Bile salt deconjugation by lactobacillus plantarum 80 and its implication for bacterial toxicity.

Journal of applied microbiology

De Boever P, Verstraete W.
PMID: 10540235
J Appl Microbiol. 1999 Sep;87(3):345-52. doi: 10.1046/j.1365-2672.1999.00019.x.

The effects of bile salts on the survival of lactobacilli were investigated using glycocholic acid, cholic acid and deoxycholic acid as model compounds and the bile salt hydrolase active Lactobacillus plantarum 80 (BSH+) and its BSH negative mutant. The...

Showing 1 to 12 of 63 entries