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The Cp(2)TiPh-Mediated Reductive Radical Cyclization of Cyanoketones and Related Reactions. Efficient Trapping of Ketyl Radicals by Cp(2)TiPh-Coordinated Polar Multiple Bonds.

The Journal of organic chemistry

Yamamoto Y, Matsumi D, Hattori R, Itoh K.
PMID: 11674424
J Org Chem. 1999 Apr 30;64(9):3224-3229. doi: 10.1021/jo982492s.

The reductive radical cyclization of cyanoketones was achieved using Cp(2)TiPh. The Ti(III) reagent was prepared by the sequential addition of i-PrMgCl and PhMgBr to commercial Cp(2)TiCl(2) in this order and used effectively without isolation. The cyclization of the gamma-...

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