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A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU.

Pharmacotherapy

Boyd C, Hassig T, MacLaren R.
PMID: 34478588
Pharmacotherapy. 2021 Oct;41(10):820-827. doi: 10.1002/phar.2621. Epub 2021 Sep 12.

OBJECTIVE: Approximately 1%-5% of critically ill patients experience clinically important gastrointestinal bleeding (CIGB). This study assessed the effectiveness and safety of proton pump inhibitors (PPIs) compared to histamine type 2 receptor antagonists (H2RAs) for prevention of CIGB in mechanically...

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Boyd C, Hassig T, MacLaren R. A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU. Pharmacotherapy. 2021;41(10):820-827doi: 10.1002/phar.2621.
Boyd, C., Hassig, T., & MacLaren, R. (2021). A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU. Pharmacotherapy, 41(10), 820-827. https://doi.org/10.1002/phar.2621
Boyd, Carly, et al. "A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU." Pharmacotherapy vol. 41,10 (2021): 820-827. doi: https://doi.org/10.1002/phar.2621
Boyd C, Hassig T, MacLaren R. A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU. Pharmacotherapy. 2021 Oct;41(10):820-827. doi: 10.1002/phar.2621. Epub 2021 Sep 12. PMID: 34478588.
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Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study.

Critical care explorations

Shiddapur A, Kistler CE, Busby-Whitehead J, Austin CA.
PMID: 34396144
Crit Care Explor. 2021 Aug 10;3(8):e0507. doi: 10.1097/CCE.0000000000000507. eCollection 2021 Aug.

Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development. We aimed to determine differential associations of histamine-2 receptor antagonist or proton-pump inhibitor administration with delirium development in...

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Shiddapur A, Kistler CE, Busby-Whitehead J, et al. Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study. Crit Care Explor. 2021;3(8):e0507doi: 10.1097/CCE.0000000000000507.
Shiddapur, A., Kistler, C. E., Busby-Whitehead, J., & Austin, C. A. (2021). Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study. Critical care explorations, 3(8), e0507. https://doi.org/10.1097/CCE.0000000000000507
Shiddapur, Ami, et al. "Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study." Critical care explorations vol. 3,8 (2021): e0507. doi: https://doi.org/10.1097/CCE.0000000000000507
Shiddapur A, Kistler CE, Busby-Whitehead J, Austin CA. Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study. Crit Care Explor. 2021 Aug 10;3(8):e0507. doi: 10.1097/CCE.0000000000000507. eCollection 2021 Aug. PMID: 34396144; PMCID: PMC8357254.
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The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients.

Journal of gastroenterology and hepatology

Chen C, Liu H, Duan R, Wang F, Duan L.
PMID: 33586808
J Gastroenterol Hepatol. 2021 Aug;36(8):2131-2140. doi: 10.1111/jgh.15432. Epub 2021 Feb 15.

BACKGROUND AND AIM: Concerns regarding adverse events associated with proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) for gastrointestinal bleeding (GIB) prophylaxis in the intensive care unit have increased in recent years. Few studies have focused on acid...

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Chen C, Liu H, Duan R, et al. The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients. J Gastroenterol Hepatol. 2021;36(8):2131-2140doi: 10.1111/jgh.15432.
Chen, C., Liu, H., Duan, R., Wang, F., & Duan, L. (2021). The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients. Journal of gastroenterology and hepatology, 36(8), 2131-2140. https://doi.org/10.1111/jgh.15432
Chen, Chen, et al. "The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients." Journal of gastroenterology and hepatology vol. 36,8 (2021): 2131-2140. doi: https://doi.org/10.1111/jgh.15432
Chen C, Liu H, Duan R, Wang F, Duan L. The efficacy and safety of acid suppressants for gastrointestinal bleeding prophylaxis in cardiac care unit patients. J Gastroenterol Hepatol. 2021 Aug;36(8):2131-2140. doi: 10.1111/jgh.15432. Epub 2021 Feb 15. PMID: 33586808; PMCID: PMC8451749.
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Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report.

Korean journal of anesthesiology

Joe S, Kim E, Park J, Lee D, Son J, Kim H.
PMID: 28367296
Korean J Anesthesiol. 2017 Apr;70(2):221-223. doi: 10.4097/kjae.2017.70.2.221. Epub 2017 Jan 11.

Serotonin syndrome is an unexpected fatal adverse event related to serotonergic medication. This case report is the first report describing the possible treatment effect of famotidine on serotonin syndrome. Furthermore, this is the first case report of serotonin syndrome...

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Joe S, Kim E, Park J, et al. Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report. Korean J Anesthesiol. 2017;70(2):221-223doi: 10.4097/kjae.2017.70.2.221.
Joe, S., Kim, E., Park, J., Lee, D., Son, J., & Kim, H. (2017). Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report. Korean journal of anesthesiology, 70(2), 221-223. https://doi.org/10.4097/kjae.2017.70.2.221
Joe, Soohyun, et al. "Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report." Korean journal of anesthesiology vol. 70,2 (2017): 221-223. doi: https://doi.org/10.4097/kjae.2017.70.2.221
Joe S, Kim E, Park J, Lee D, Son J, Kim H. Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report. Korean J Anesthesiol. 2017 Apr;70(2):221-223. doi: 10.4097/kjae.2017.70.2.221. Epub 2017 Jan 11. PMID: 28367296; PMCID: PMC5370302.
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Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel - proton pump inhibitor interaction.

Pharmacology research & perspectives

Kruik-Kollöffel WJ, van der Palen J, Kruik HJ, van Herk-Sukel MP, Movig KL.
PMID: 28116095
Pharmacol Res Perspect. 2016 Jul 18;4(4):e00242. doi: 10.1002/prp2.242. eCollection 2016 Aug.

Safety concerns of the concomitant use of clopidogrel and proton pump inhibitors (PPIs) were published in 2009 and 2010 by the medicines regulatory agencies, including a direct healthcare professional communication. We examined the association between various safety statements and...

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Kruik-Kollöffel WJ, van der Palen J, Kruik HJ, et al. Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel - proton pump inhibitor interaction. Pharmacol Res Perspect. 2016;4(4):e00242doi: 10.1002/prp2.242.
Kruik-Kollöffel, W. J., van der Palen, J., Kruik, H. J., van Herk-Sukel, M. P., & Movig, K. L. (2016). Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel - proton pump inhibitor interaction. Pharmacology research & perspectives, 4(4), e00242. https://doi.org/10.1002/prp2.242
Kruik-Kollöffel, Willemien J, et al. "Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel - proton pump inhibitor interaction." Pharmacology research & perspectives vol. 4,4 (2016): e00242. doi: https://doi.org/10.1002/prp2.242
Kruik-Kollöffel WJ, van der Palen J, Kruik HJ, van Herk-Sukel MP, Movig KL. Prescription behavior for gastroprotective drugs in new users as a result of communications regarding clopidogrel - proton pump inhibitor interaction. Pharmacol Res Perspect. 2016 Jul 18;4(4):e00242. doi: 10.1002/prp2.242. eCollection 2016 Aug. PMID: 28116095; PMCID: PMC5242171.
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Infantile Gastroesophageal Reflux: Adherence to Treatment Guidelines in the Hospital Setting.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Long HA, Solski L, Rebuck JA, Bridgeman C.
PMID: 29491751
J Pediatr Pharmacol Ther. 2018 Jan-Feb;23(1):41-47. doi: 10.5863/1551-6776-23.1.41.

OBJECTIVES: Recent guidelines defined and differentiated the management of gastroesophageal reflux (GER) and gastroesophageal reflux disease (GERD). The guidelines recommend against using empiric acid suppression therapy for infantile GER. The primary objective of this study was to assess inpatient...

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Long HA, Solski L, Rebuck JA, et al. Infantile Gastroesophageal Reflux: Adherence to Treatment Guidelines in the Hospital Setting. J Pediatr Pharmacol Ther. 2018;23(1):41-47doi: 10.5863/1551-6776-23.1.41.
Long, H. A., Solski, L., Rebuck, J. A., & Bridgeman, C. (2018). Infantile Gastroesophageal Reflux: Adherence to Treatment Guidelines in the Hospital Setting. The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 23(1), 41-47. https://doi.org/10.5863/1551-6776-23.1.41
Long, Heather A, et al. "Infantile Gastroesophageal Reflux: Adherence to Treatment Guidelines in the Hospital Setting." The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG vol. 23,1 (2018): 41-47. doi: https://doi.org/10.5863/1551-6776-23.1.41
Long HA, Solski L, Rebuck JA, Bridgeman C. Infantile Gastroesophageal Reflux: Adherence to Treatment Guidelines in the Hospital Setting. J Pediatr Pharmacol Ther. 2018 Jan-Feb;23(1):41-47. doi: 10.5863/1551-6776-23.1.41. PMID: 29491751; PMCID: PMC5823492.
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Indication of acid suppression therapy and predictors for the prophylactic use of protonpump inhibitors vs. histamine-2 receptor antagonists in a Malaysian tertiary hospital.

Pharmacy practice

Oh AL, Tan AG, Phan HS, Lee BC, Jumaat N, Chew SP, Wong SH, Ting SH, Subramaniam T.
PMID: 26445624
Pharm Pract (Granada). 2015 Apr-Jun;13(3):633. doi: 10.18549/PharmPract.2015.03.633. Epub 2015 Jun 15.

BACKGROUND: Proton-pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA) are common acid suppressants used in gastrointestinal disorders. The trend of usage in Malaysia has changed from predominantly H2RA to PPI from 2007 to 2008, 3.46 versus 2.87 and 2.99...

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Oh AL, Tan AG, Phan HS, et al. Indication of acid suppression therapy and predictors for the prophylactic use of protonpump inhibitors vs. histamine-2 receptor antagonists in a Malaysian tertiary hospital. Pharm Pract (Granada). 2015;13(3):633doi: 10.18549/PharmPract.2015.03.633.
Oh, A. L., Tan, A. G., Phan, H. S., Lee, B. C., Jumaat, N., Chew, S. P., Wong, S. H., Ting, S. H., & Subramaniam, T. (2015). Indication of acid suppression therapy and predictors for the prophylactic use of protonpump inhibitors vs. histamine-2 receptor antagonists in a Malaysian tertiary hospital. Pharmacy practice, 13(3), 633. https://doi.org/10.18549/PharmPract.2015.03.633
Oh, Ai L, et al. "Indication of acid suppression therapy and predictors for the prophylactic use of protonpump inhibitors vs. histamine-2 receptor antagonists in a Malaysian tertiary hospital." Pharmacy practice vol. 13,3 (2015): 633. doi: https://doi.org/10.18549/PharmPract.2015.03.633
Oh AL, Tan AG, Phan HS, Lee BC, Jumaat N, Chew SP, Wong SH, Ting SH, Subramaniam T. Indication of acid suppression therapy and predictors for the prophylactic use of protonpump inhibitors vs. histamine-2 receptor antagonists in a Malaysian tertiary hospital. Pharm Pract (Granada). 2015 Apr-Jun;13(3):633. doi: 10.18549/PharmPract.2015.03.633. Epub 2015 Jun 15. PMID: 26445624; PMCID: PMC4582748.
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Effects of histamine H2-antagonists on pre- and post-natal development in the rat.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Freeman P, Sturman G, Suhonen AM, Meade HM, Seeley NA.
PMID: 27518001
Inflamm Res. 1997 Mar;46:55-6. doi: 10.1007/s000110050067.

No abstract available.

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Freeman P, Sturman G, Suhonen AM, et al. Effects of histamine H2-antagonists on pre- and post-natal development in the rat. Inflamm Res. 1997;46:55-6doi: 10.1007/s000110050067.
Freeman, P., Sturman, G., Suhonen, A. M., Meade, H. M., & Seeley, N. A. (1997). Effects of histamine H2-antagonists on pre- and post-natal development in the rat. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 4655-6. https://doi.org/10.1007/s000110050067
Freeman, P, et al. "Effects of histamine H2-antagonists on pre- and post-natal development in the rat." Inflammation research : official journal of the European Histamine Research Society ... [et al.] vol. 46 (1997): 55-6. doi: https://doi.org/10.1007/s000110050067
Freeman P, Sturman G, Suhonen AM, Meade HM, Seeley NA. Effects of histamine H2-antagonists on pre- and post-natal development in the rat. Inflamm Res. 1997 Mar;46:55-6. doi: 10.1007/s000110050067. PMID: 27518001.
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The management of gastro-oesophageal reflux disease.

Australian prescriber

Keung C, Hebbard G.
PMID: 27041798
Aust Prescr. 2016 Feb;39(1):6-10. doi: 10.18773/austprescr.2016.003. Epub 2016 Feb 01.

If there are no features of serious disease, suspected gastro-oesophageal reflux disease can be initially managed with a trial of a proton pump inhibitor for 4-8 weeks. This should be taken 30-60 minutes before food for optimal effect. Once...

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Keung C, Hebbard G. The management of gastro-oesophageal reflux disease. Aust Prescr. 2016;39(1):6-10doi: 10.18773/austprescr.2016.003.
Keung, C., & Hebbard, G. (2016). The management of gastro-oesophageal reflux disease. Australian prescriber, 39(1), 6-10. https://doi.org/10.18773/austprescr.2016.003
Keung, Charlotte, and Hebbard, Geoffrey. "The management of gastro-oesophageal reflux disease." Australian prescriber vol. 39,1 (2016): 6-10. doi: https://doi.org/10.18773/austprescr.2016.003
Keung C, Hebbard G. The management of gastro-oesophageal reflux disease. Aust Prescr. 2016 Feb;39(1):6-10. doi: 10.18773/austprescr.2016.003. Epub 2016 Feb 01. PMID: 27041798; PMCID: PMC4816873.
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Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis.

World journal of critical care medicine

Buendgens L, Koch A, Tacke F.
PMID: 26855894
World J Crit Care Med. 2016 Feb 04;5(1):57-64. doi: 10.5492/wjccm.v5.i1.57. eCollection 2016 Feb 04.

Stress-related mucosal disease is a typical complication of critically ill patients in the intensive care unit (ICU). It poses a risk of clinically relevant upper gastrointestinal (GI) bleeding. Therefore, stress ulcer prophylaxis (SUP) is recommended in high-risk patients, especially...

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Buendgens L, Koch A, Tacke F. Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis. World J Crit Care Med. 2016;5(1):57-64doi: 10.5492/wjccm.v5.i1.57.
Buendgens, L., Koch, A., & Tacke, F. (2016). Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis. World journal of critical care medicine, 5(1), 57-64. https://doi.org/10.5492/wjccm.v5.i1.57
Buendgens, Lukas, et al. "Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis." World journal of critical care medicine vol. 5,1 (2016): 57-64. doi: https://doi.org/10.5492/wjccm.v5.i1.57
Buendgens L, Koch A, Tacke F. Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis. World J Crit Care Med. 2016 Feb 04;5(1):57-64. doi: 10.5492/wjccm.v5.i1.57. eCollection 2016 Feb 04. PMID: 26855894; PMCID: PMC4733456.
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Showing 1 to 10 of 10 entries