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Showing 1 to 12 of 73 entries
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Histamine and histamine receptor regulation of gastrointestinal cancers.

Translational gastrointestinal cancer

Kennedy L, Hodges K, Meng F, Alpini G, Francis H.
PMID: 24639917
Transl Gastrointest Cancer. 2012 Oct;1(3):215-227.

Histamine is a neurotransmitter released throughout the body that regulates multiple physiological responses. Primarily histamine is acknowledged for its role in inflammatory reactions to foreign pathogens that enter the body. Aside from inflammatory responses, histamine expression and synthesis has...

Gastric secretion.

Current opinion in gastroenterology

Schubert ML.
PMID: 17031123
Curr Opin Gastroenterol. 2000 Nov;16(6):463-8. doi: 10.1097/00001574-200011000-00002.

This article summarizes data published during the past year that improve our understanding of the mechanisms by which various neurotransmitters, paracrine agents, and hormones regulate gastric acid secretion and are themselves regulated. The main stimulants of acid secretion are...

Gastric carcinomas localized to the cardia.

Gastroenterology research and practice

Bakkelund KE, Nordrum IS, Fossmark R, Waldum HL.
PMID: 22474435
Gastroenterol Res Pract. 2012;2012:457831. doi: 10.1155/2012/457831. Epub 2012 Feb 28.

Objectives. Gastric adenocarcinomas localized to the cardia are increasing. Enterochromaffin-like (ECL) cells play a role in gastric carcinogenesis in hypergastrinemia, and the use of proton pump inhibitors (PPI) leading to hypergastrinemia has increased considerably during the last decades. We...

Role of Histidine and Tyrosine Decarboxylases and Mono- and Diamine Oxidases in Amine Build-Up in Cheese.

Journal of food protection

Voigt MN, Eitenmiller RR.
PMID: 30795038
J Food Prot. 1978 Mar;41(3):182-186. doi: 10.4315/0362-028X-41.3.182.

Presence of biologically active amines in foods has been recognized for about 20 years. Past research on amines such as tyramine and histamine has not investigated factors which account for the variable concentrations often found in food products. This...

Histamine Production by Psychrotrophic Pseudomonads Isolated from Tuna Fish.

Journal of food protection

Ryser ET, Marth EH, Taylor SL.
PMID: 30934415
J Food Prot. 1984 May;47(5):378-380. doi: 10.4315/0362-028X-47.5.378.

Sixty isolates of psychrotrophic bacteria obtained from raw tuna fish were identified as Pseudomonas fluorescens , Pseudomonas putida and non-fluorescent Pseudomonas sp., and were tested for their ability to produce histamine. Following incubation in modified histidine decarboxylase broth, 28%...

Hdc-expressing myeloid-derived suppressor cells promote basal-like transition and metastasis of breast cancer.

International journal of clinical and experimental pathology

Chen N, Feng Q, Deng J, Xiong Y, Deng YJ, Wang MM, Zhou L, Yu QW, Hu JP, Deng H.
PMID: 32661481
Int J Clin Exp Pathol. 2020 Jun 01;13(6):1431-1443. eCollection 2020.

Metastases are the greatest contributors to death from breast cancer. Here, we identified a distinct subpopulation of luminal breast cancer characterized by cytokeratin 14 (CK14) expression in secondary colonies rather than primary tumors. This entity possessed a poorer prognosis...

Abnormal histidine metabolism promotes macrophage lipid accumulation under Ox-LDL condition.

Biochemical and biophysical research communications

Zhu B, Zhang Z, Wang X, Zhang W, Shi H, Song Z, Ding S, Yang X.
PMID: 34954523
Biochem Biophys Res Commun. 2022 Jan 15;588:161-167. doi: 10.1016/j.bbrc.2021.12.069. Epub 2021 Dec 20.

Distinct macrophage populations exert highly heterogeneity and perform various functions, among which, a crucial function of lipid metabolism is highlighted. However, the role of histidine metabolism disorder in macrophage lipid metabolism remains elusive. Addressed this question, we sorted and...

Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.

Journal of biochemistry

Oda Y, Nakata K, Miyano H, Mizukoshi T, Yamaguchi H, Kashiwagi T.
PMID: 34622278
J Biochem. 2021 Oct 08; doi: 10.1093/jb/mvab103. Epub 2021 Oct 08.

Enzymatic amino acid assays are important in physiological research and clinical diagnostics because abnormal amino acid concentrations in biofluids are associated with various diseases. L-histidine decarboxylase from Photobacterium phosphoreum (PpHDC) is a pyridoxal 5'-phosphate-dependent enzyme and a candidate for...

The bullies are the leaders of the next generation: Inherited aminergic neurotransmitter system changes in socially dominant zebrafish, Danio rerio.

Behavioural brain research

Sundvik M, Puttonen H, Semenova S, Panula P.
PMID: 33878430
Behav Brain Res. 2021 Jul 09;409:113309. doi: 10.1016/j.bbr.2021.113309. Epub 2021 Apr 18.

We studied the social hierarchy in zebrafish and assessed differences in neurotransmitters and behavior in the F1 generation offspring of dominant and subordinate zebrafish (Danio rerio). We used behavioral assays to study locomotion, ability to complete cognitive tasks, social...

Bacteriological Quality of Tuna Fish ( Thunnus thynnus ) Destined for Canning: Effect of Tuna Handling on Presence of Histidine Decarboxylase Bacteria and Histamine Level.

Journal of food protection

López-Sabater EI, Rodríguez-Jerez JJ, Roig-Sagués AX, Teresa Mora-Ventura MA.
PMID: 31113133
J Food Prot. 1994 Apr;57(4):318-323. doi: 10.4315/0362-028X-57.4.318.

The present paper analyzes the bacteriological quality and histamine content of tuna fish samples destined for canning. Raw material used in the canning process was of good quality. Histamine-producing bacteria counts were only found in three samples from the...

Histidine decarboxylase-expressing PMN-MDSC-derived TGF-β1 promotes the epithelial-mesenchymal transition of metastatic lung adenocarcinoma.

International journal of clinical and experimental pathology

Fu XG, Deng J, Xu WJ, Chen JY, Sun J, Deng H.
PMID: 32661471
Int J Clin Exp Pathol. 2020 Jun 01;13(6):1361-1371. eCollection 2020.

Metastasis is a major risk for lung adenocarcinoma-related mortality. Accumulating evidence raises the possibility that anticancer therapies might be more sensitive by targeting premetastatic niches in addition to the cancer cells themselves. Here, we identified a subpopulation of metastatic...

Inhibition of Amino Acid Decarboxylase Activity of Enterobacter aerogenes by Active Components in Spices.

Journal of food protection

Wendakoon CN, Sakaguchi M.
PMID: 31137282
J Food Prot. 1995 Mar;58(3):280-283. doi: 10.4315/0362-028X-58.3.280.

The water and ethanol extracts of several commercially available spices were examined for their inhibitory action on the decarboxylase activity of a crude extract of Enterobacter aerogenes . The water extracts had a negligible effect on histidine decarboxylase activity,...

Showing 1 to 12 of 73 entries