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Preparation of alkyl (R)-(-)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(-)-3-hydroxybutyrate.

Enzyme and microbial technology

Lee Y, Park SH, Lim IT, Han K, Lee SY.
PMID: 10862899
Enzyme Microb Technol. 2000 Jul 01;27(1):33-36. doi: 10.1016/s0141-0229(00)00146-0.

An efficient method for the preparation of optically active alkyl (R)-(-)-3-hydroxybutyrates by chemical depolymerization of biopolymer, poly-(R)-(-)-(3-hydroxybutyrate), was established. This method consists of simple recovery of poly-(R)-(-)-(3-hydroxybutyrate) from bacterial cells followed by acidic alcoholysis. When poly-(R)-(-)-(3-hydroxybutyrate) was purified by...

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Lee Y, Park SH, Lim IT, et al. Preparation of alkyl (R)-(-)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(-)-3-hydroxybutyrate. Enzyme Microb Technol. 2000;27(1):33-36doi: 10.1016/s0141-0229(00)00146-0.
Lee, Y., Park, S. H., Lim, I. T., Han, K., & Lee, S. Y. (2000). Preparation of alkyl (R)-(-)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(-)-3-hydroxybutyrate. Enzyme and microbial technology, 27(1), 33-36. https://doi.org/10.1016/s0141-0229(00)00146-0
Lee, et al. "Preparation of alkyl (R)-(-)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(-)-3-hydroxybutyrate." Enzyme and microbial technology vol. 27,1 (2000): 33-36. doi: https://doi.org/10.1016/s0141-0229(00)00146-0
Lee Y, Park SH, Lim IT, Han K, Lee SY. Preparation of alkyl (R)-(-)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(-)-3-hydroxybutyrate. Enzyme Microb Technol. 2000 Jul 01;27(1):33-36. doi: 10.1016/s0141-0229(00)00146-0. PMID: 10862899.
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Clinical and biochemical characteristics and analysis of risk factors for euglycaemic diabetic ketoacidosis in type 2 diabetic individuals treated with SGLT2 inhibitors: A review of 72 cases over a 4.5-year period.

Diabetes & metabolic syndrome

Menghoum N, Oriot P, Hermans MP.
PMID: 34562870
Diabetes Metab Syndr. 2021 Nov-Dec;15(6):102275. doi: 10.1016/j.dsx.2021.102275. Epub 2021 Sep 15.

BACKGROUND AND AIMS: To study euglycemic diabetic ketoacidosis (euDKA) outcomes associated with sodium-glucose co-transporter 2 inhibitors (SGLT2is) METHODS: Review of 72 euDKA cases in T2DM between September 2015 and January 2020 (PUBMED).RESULTS: euDKA could occur at any time during...

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Menghoum N, Oriot P, Hermans MP. Clinical and biochemical characteristics and analysis of risk factors for euglycaemic diabetic ketoacidosis in type 2 diabetic individuals treated with SGLT2 inhibitors: A review of 72 cases over a 4.5-year period. Diabetes Metab Syndr. 2021;15(6):102275doi: 10.1016/j.dsx.2021.102275.
Menghoum, N., Oriot, P., & Hermans, M. P. (2021). Clinical and biochemical characteristics and analysis of risk factors for euglycaemic diabetic ketoacidosis in type 2 diabetic individuals treated with SGLT2 inhibitors: A review of 72 cases over a 4.5-year period. Diabetes & metabolic syndrome, 15(6), 102275. https://doi.org/10.1016/j.dsx.2021.102275
Menghoum, N, et al. "Clinical and biochemical characteristics and analysis of risk factors for euglycaemic diabetic ketoacidosis in type 2 diabetic individuals treated with SGLT2 inhibitors: A review of 72 cases over a 4.5-year period." Diabetes & metabolic syndrome vol. 15,6 (2021): 102275. doi: https://doi.org/10.1016/j.dsx.2021.102275
Menghoum N, Oriot P, Hermans MP. Clinical and biochemical characteristics and analysis of risk factors for euglycaemic diabetic ketoacidosis in type 2 diabetic individuals treated with SGLT2 inhibitors: A review of 72 cases over a 4.5-year period. Diabetes Metab Syndr. 2021 Nov-Dec;15(6):102275. doi: 10.1016/j.dsx.2021.102275. Epub 2021 Sep 15. PMID: 34562870.
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Aging markers in human urine: A comprehensive, non-targeted LC-MS study.

FASEB bioAdvances

Teruya T, Goga H, Yanagida M.
PMID: 33336159
FASEB Bioadv. 2020 Oct 21;2(12):720-733. doi: 10.1096/fba.2020-00047. eCollection 2020 Dec.

Metabolites in human biofluids document the physiological status of individuals. We conducted comprehensive, non-targeted, non-invasive metabolomic analysis of urine from 27 healthy human subjects, comprising 13 young adults (30 ± 3 years) and 14 seniors (76 ± 4 years)....

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Teruya T, Goga H, Yanagida M. Aging markers in human urine: A comprehensive, non-targeted LC-MS study. FASEB Bioadv. 2020;2(12):720-733doi: 10.1096/fba.2020-00047.
Teruya, T., Goga, H., & Yanagida, M. (2020). Aging markers in human urine: A comprehensive, non-targeted LC-MS study. FASEB bioAdvances, 2(12), 720-733. https://doi.org/10.1096/fba.2020-00047
Teruya, Takayuki, et al. "Aging markers in human urine: A comprehensive, non-targeted LC-MS study." FASEB bioAdvances vol. 2,12 (2020): 720-733. doi: https://doi.org/10.1096/fba.2020-00047
Teruya T, Goga H, Yanagida M. Aging markers in human urine: A comprehensive, non-targeted LC-MS study. FASEB Bioadv. 2020 Oct 21;2(12):720-733. doi: 10.1096/fba.2020-00047. eCollection 2020 Dec. PMID: 33336159; PMCID: PMC7734427.
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Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS.

SpringerPlus

Miyazaki T, Honda A, Ikegami T, Iwamoto J, Monma T, Hirayama T, Saito Y, Yamashita K, Matsuzaki Y.
PMID: 26389019
Springerplus. 2015 Sep 15;4:494. doi: 10.1186/s40064-015-1304-0. eCollection 2015.

We have developed a highly sensitive and specific method for quantification of salivary 3-hydroxybutyrate (3HB), 3-hydroxyisobutyrate (3HIB), 3-hydroxy-3-methylbutyrate (3HMB) and 2-hydroxybutyrate (2HB), which could be new non-invasive biomarkers for catabolic pathways of fatty acids/ketogenic amino acids, valine, leucine, and...

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Miyazaki T, Honda A, Ikegami T, et al. Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS. Springerplus. 2015;4:494doi: 10.1186/s40064-015-1304-0.
Miyazaki, T., Honda, A., Ikegami, T., Iwamoto, J., Monma, T., Hirayama, T., Saito, Y., Yamashita, K., & Matsuzaki, Y. (2015). Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS. SpringerPlus, 4494. https://doi.org/10.1186/s40064-015-1304-0
Miyazaki, Teruo, et al. "Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS." SpringerPlus vol. 4 (2015): 494. doi: https://doi.org/10.1186/s40064-015-1304-0
Miyazaki T, Honda A, Ikegami T, Iwamoto J, Monma T, Hirayama T, Saito Y, Yamashita K, Matsuzaki Y. Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS. Springerplus. 2015 Sep 15;4:494. doi: 10.1186/s40064-015-1304-0. eCollection 2015. PMID: 26389019; PMCID: PMC4571036.
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Comparing Finger-stick β-Hydroxybutyrate with Dipstick Urine Tests in the Detection of Ketone Bodies.

Turkish journal of emergency medicine

Kuru B, Sever M, Aksay E, Dogan T, Yalcin N, Eren ES, Ustuner F.
PMID: 27331169
Turk J Emerg Med. 2016 Feb 26;14(2):47-52. doi: 10.5505/1304.7361.2014.14880. eCollection 2014 Jun.

OBJECTIVES: Blood ketone (beta-hydroxybutyrate) measurements are suggested instead of urine ketone (acetoacetate) measurements in the diagnosis of diabetic ketoacidosis. Urine ketone examination is difficult and time consuming, and may result in an incorrect interpretation. Studies performed in emergency departments...

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Kuru B, Sever M, Aksay E, et al. Comparing Finger-stick β-Hydroxybutyrate with Dipstick Urine Tests in the Detection of Ketone Bodies. Turk J Emerg Med. 2016;14(2):47-52doi: 10.5505/1304.7361.2014.14880.
Kuru, B., Sever, M., Aksay, E., Dogan, T., Yalcin, N., Eren, E. S., & Ustuner, F. (2014). Comparing Finger-stick β-Hydroxybutyrate with Dipstick Urine Tests in the Detection of Ketone Bodies. Turkish journal of emergency medicine, 14(2), 47-52. https://doi.org/10.5505/1304.7361.2014.14880
Kuru, Baris, et al. "Comparing Finger-stick β-Hydroxybutyrate with Dipstick Urine Tests in the Detection of Ketone Bodies." Turkish journal of emergency medicine vol. 14,2 (2014): 47-52. doi: https://doi.org/10.5505/1304.7361.2014.14880
Kuru B, Sever M, Aksay E, Dogan T, Yalcin N, Eren ES, Ustuner F. Comparing Finger-stick β-Hydroxybutyrate with Dipstick Urine Tests in the Detection of Ketone Bodies. Turk J Emerg Med. 2016 Feb 26;14(2):47-52. doi: 10.5505/1304.7361.2014.14880. eCollection 2014 Jun. PMID: 27331169; PMCID: PMC4909883.
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Nutritional Ketosis Increases NAD.

Frontiers in nutrition

Xin L, Ipek Ö, Beaumont M, Shevlyakova M, Christinat N, Masoodi M, Greenberg N, Gruetter R, Cuenoud B.
PMID: 30050907
Front Nutr. 2018 Jul 12;5:62. doi: 10.3389/fnut.2018.00062. eCollection 2018.

Ketones represent an important alternative fuel for the brain under glucose hypo-metabolic conditions induced by neurological diseases or aging, however their metabolic consequences in healthy brain remain unclear. Here we report that ketones can increase the redox NAD

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Xin L, Ipek Ö, Beaumont M, et al. Nutritional Ketosis Increases NAD. Front Nutr. 2018;5:62doi: 10.3389/fnut.2018.00062.
Xin, L., Ipek, �. �., Beaumont, M., Shevlyakova, M., Christinat, N., Masoodi, M., Greenberg, N., Gruetter, R., & Cuenoud, B. (2018). Nutritional Ketosis Increases NAD. Frontiers in nutrition, 562. https://doi.org/10.3389/fnut.2018.00062
Xin, Lijing, et al. "Nutritional Ketosis Increases NAD." Frontiers in nutrition vol. 5 (2018): 62. doi: https://doi.org/10.3389/fnut.2018.00062
Xin L, Ipek Ö, Beaumont M, Shevlyakova M, Christinat N, Masoodi M, Greenberg N, Gruetter R, Cuenoud B. Nutritional Ketosis Increases NAD. Front Nutr. 2018 Jul 12;5:62. doi: 10.3389/fnut.2018.00062. eCollection 2018. PMID: 30050907; PMCID: PMC6052097.
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Showing 1 to 6 of 6 entries