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Effects of angiotensin II on the cerebral circulation: role of oxidative stress.

Frontiers in physiology

De Silva TM, Faraci FM.
PMID: 23316164
Front Physiol. 2013 Jan 03;3:484. doi: 10.3389/fphys.2012.00484. eCollection 2012.

Oxidative stress has emerged as a key component of many diseases that affect the vasculature. Oxidative stress is characterized as a cellular environment where the generation of oxidant molecules overwhelms endogenous anti-oxidant defense mechanisms. NADPH oxidases are a family...

Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction.

Stroke

De Silva TM, Modrick ML, Grobe JL, Faraci FM.
PMID: 34107734
Stroke. 2021 Jul;52(7):2404-2413. doi: 10.1161/STROKEAHA.121.034984. Epub 2021 Jun 10.

[Figure: see text].

Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction.

Stroke

De Silva TM, Modrick ML, Grobe JL, Faraci FM.
PMID: 34107734
Stroke. 2021 Jul;52(7):2404-2413. doi: 10.1161/STROKEAHA.121.034984. Epub 2021 Jun 10.

BACKGROUND AND PURPOSE: Hypertension is a leading risk factor for cerebrovascular disease and loss of brain health. While the brain renin-angiotensin system (RAS) contributes to hypertension, its potential impact on the local vasculature is unclear. We tested the hypothesis...

Showing 1 to 3 of 3 entries