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Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks.

Cell death discovery

Ishii M, Rohrer B.
PMID: 28179989
Cell Death Discov. 2017 Feb 06;3:16071. doi: 10.1038/cddiscovery.2016.71. eCollection 2017.

'Bystander effect' refers to the induction of biological effects in cells not directly targeted. The retinal pigment epithelium consists of hexagonal cells, forming a monolayer interconnected by gap junctions (GJs). Oxidative stress initiated in an individual cell by photostimulation...

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Ishii M, Rohrer B. Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks. Cell Death Discov. 2017;3:16071doi: 10.1038/cddiscovery.2016.71.
Ishii, M., & Rohrer, B. (2017). Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks. Cell death discovery, 316071. https://doi.org/10.1038/cddiscovery.2016.71
Ishii, Masaaki, and Rohrer, Bärbel. "Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks." Cell death discovery vol. 3 (2017): 16071. doi: https://doi.org/10.1038/cddiscovery.2016.71
Ishii M, Rohrer B. Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks. Cell Death Discov. 2017 Feb 06;3:16071. doi: 10.1038/cddiscovery.2016.71. eCollection 2017. PMID: 28179989; PMCID: PMC5292780.
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Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

Beeson C, Peterson YK, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, Comer RF, Lindsey CC, Schnellmann RG, Rohrer B.
PMID: 33945330
J Ocul Pharmacol Ther. 2021 Jul-Aug;37(6):367-378. doi: 10.1089/jop.2020.0140. Epub 2021 May 04.

No abstract available.

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Beeson C, Peterson YK, Perron N, et al. Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. J Ocul Pharmacol Ther. 2021;37(6):367-378doi: 10.1089/jop.2020.0140.
Beeson, C., Peterson, Y. K., Perron, N., Bandyopadhyay, M., Nasarre, C., Beeson, G., Comer, R. F., Lindsey, C. C., Schnellmann, R. G., & Rohrer, B. (2021). Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 37(6), 367-378. https://doi.org/10.1089/jop.2020.0140
Beeson, Craig, et al. "Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models." Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics vol. 37,6 (2021): 367-378. doi: https://doi.org/10.1089/jop.2020.0140
Beeson C, Peterson YK, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, Comer RF, Lindsey CC, Schnellmann RG, Rohrer B. Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. J Ocul Pharmacol Ther. 2021 Jul-Aug;37(6):367-378. doi: 10.1089/jop.2020.0140. Epub 2021 May 04. PMID: 33945330; PMCID: PMC8328042.
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Anaphylatoxins Activate Ca.

Frontiers in immunology

Busch C, Annamalai B, Abdusalamova K, Reichhart N, Huber C, Lin Y, Jo EAH, Zipfel PF, Skerka C, Wildner G, Diedrichs-Möhring M, Rohrer B, Strauß O.
PMID: 28663750
Front Immunol. 2017 Jun 15;8:703. doi: 10.3389/fimmu.2017.00703. eCollection 2017.

METHODS: Individual activities of and interaction between the two anaphylatoxin receptors were tested in cultured RPE cells by fluorescence microscopy, western blot, and immunohistochemistry.MAIN OUTCOME MEASURES: Intracellular free calcium, protein phosphorylation, immunostaining of tissues/cells, and multiplex secretion assay.RESULTS: Similar...

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Busch C, Annamalai B, Abdusalamova K, et al. Anaphylatoxins Activate Ca. Front Immunol. 2017;8:703doi: 10.3389/fimmu.2017.00703.
Busch, C., Annamalai, B., Abdusalamova, K., Reichhart, N., Huber, C., Lin, Y., Jo, E. A. H., Zipfel, P. F., Skerka, C., Wildner, G., Diedrichs-Möhring, M., Rohrer, B., & Strauß, O. (2017). Anaphylatoxins Activate Ca. Frontiers in immunology, 8703. https://doi.org/10.3389/fimmu.2017.00703
Busch, Catharina, et al. "Anaphylatoxins Activate Ca." Frontiers in immunology vol. 8 (2017): 703. doi: https://doi.org/10.3389/fimmu.2017.00703
Busch C, Annamalai B, Abdusalamova K, Reichhart N, Huber C, Lin Y, Jo EAH, Zipfel PF, Skerka C, Wildner G, Diedrichs-Möhring M, Rohrer B, Strauß O. Anaphylatoxins Activate Ca. Front Immunol. 2017 Jun 15;8:703. doi: 10.3389/fimmu.2017.00703. eCollection 2017. PMID: 28663750; PMCID: PMC5472091.
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Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization.

Molecular therapy. Methods & clinical development

Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B.
PMID: 29234687
Mol Ther Methods Clin Dev. 2017 Nov 10;9:1-11. doi: 10.1016/j.omtm.2017.11.003. eCollection 2018 Jun 15.

Complement activation plays a significant role in age-related macular degeneration (AMD) pathogenesis, and polymorphisms interfering with factor H (fH) function, a complement alternative pathway (AP) inhibitor, are associated with increased AMD risk. We have previously validated an AP inhibitor,...

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Schnabolk G, Parsons N, Obert E, et al. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Mol Ther Methods Clin Dev. 2017;9:1-11doi: 10.1016/j.omtm.2017.11.003.
Schnabolk, G., Parsons, N., Obert, E., Annamalai, B., Nasarre, C., Tomlinson, S., Lewin, A. S., & Rohrer, B. (2018). Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Molecular therapy. Methods & clinical development, 91-11. https://doi.org/10.1016/j.omtm.2017.11.003
Schnabolk, Gloriane, et al. "Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization." Molecular therapy. Methods & clinical development vol. 9 (2018): 1-11. doi: https://doi.org/10.1016/j.omtm.2017.11.003
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, Lewin AS, Rohrer B. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Mol Ther Methods Clin Dev. 2017 Nov 10;9:1-11. doi: 10.1016/j.omtm.2017.11.003. eCollection 2018 Jun 15. PMID: 29234687; PMCID: PMC5723362.
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The role of the immune response in age-related macular degeneration.

International journal of inflammation

Whitcup SM, Sodhi A, Atkinson JP, Holers VM, Sinha D, Rohrer B, Dick AD.
PMID: 23762772
Int J Inflam. 2013;2013:348092. doi: 10.1155/2013/348092. Epub 2013 May 23.

Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries; with the aging population, the negative health impacts and costs of the disease will increase dramatically over the next decade. Although the exact cause of AMD...

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Whitcup SM, Sodhi A, Atkinson JP, et al. The role of the immune response in age-related macular degeneration. Int J Inflam. 2013;2013:348092doi: 10.1155/2013/348092.
Whitcup, S. M., Sodhi, A., Atkinson, J. P., Holers, V. M., Sinha, D., Rohrer, B., & Dick, A. D. (2013). The role of the immune response in age-related macular degeneration. International journal of inflammation, 2013348092. https://doi.org/10.1155/2013/348092
Whitcup, Scott M, et al. "The role of the immune response in age-related macular degeneration." International journal of inflammation vol. 2013 (2013): 348092. doi: https://doi.org/10.1155/2013/348092
Whitcup SM, Sodhi A, Atkinson JP, Holers VM, Sinha D, Rohrer B, Dick AD. The role of the immune response in age-related macular degeneration. Int J Inflam. 2013;2013:348092. doi: 10.1155/2013/348092. Epub 2013 May 23. PMID: 23762772; PMCID: PMC3676958.
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Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line.

The Journal of biological chemistry

Sharma AK, Rohrer B.
PMID: 28801351
J Biol Chem. 2017 Aug 11;292(32):13186. doi: 10.1074/jbc.A117.401037.

No abstract available.

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Sharma AK, Rohrer B. Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line. J Biol Chem. 2017;292(32):13186doi: 10.1074/jbc.A117.401037.
Sharma, A. K., & Rohrer, B. (2017). Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line. The Journal of biological chemistry, 292(32), 13186. https://doi.org/10.1074/jbc.A117.401037
Sharma, Ashish K, and Rohrer, Baerbel. "Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line." The Journal of biological chemistry vol. 292,32 (2017): 13186. doi: https://doi.org/10.1074/jbc.A117.401037
Sharma AK, Rohrer B. Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line. J Biol Chem. 2017 Aug 11;292(32):13186. doi: 10.1074/jbc.A117.401037. PMID: 28801351; PMCID: PMC5555181.
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Showing 1 to 6 of 6 entries