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The application of laboratory-based analytical tools and techniques for the quality assessment and improvement of commercial antivenoms used in the treatment of snakebite envenomation.

Drug testing and analysis

Patra A, Herrera M, Gutiérrez JM, Mukherjee AK.
PMID: 34089574
Drug Test Anal. 2021 Aug;13(8):1471-1489. doi: 10.1002/dta.3108. Epub 2021 Jun 18.

Snakebite envenomation is a public health problem of high impact, particularly for the developing world. Antivenom, which contains whole or protease-digested immunoglobulin G, purified from the plasma of hyper-immunized animals (mainly horses), is the mainstay for the treatment of...

Tumor-infiltrating B cells producing antitumor active immunoglobulins in resected HCC prolong patient survival.

Oncotarget

Brunner SM, Itzel T, Rubner C, Kesselring R, Griesshammer E, Evert M, Teufel A, Schlitt HJ, Fichtner-Feigl S.
PMID: 29050338
Oncotarget. 2017 Aug 09;8(41):71002-71011. doi: 10.18632/oncotarget.20238. eCollection 2017 Sep 19.

BACKGROUND & AIMS: The immunological microenvironment of HCC influences patient outcome, however, the role of B cells remains unclear. This study investigated effects of local B-cell infiltration in HCC cohorts on patient survival and immunological and molecular tumor microenvironment.RESULTS:...

Junctional Bradycardia as Early Sign of Digoxin Toxicity in a Premature Infant with Congestive Heart Failure due to a Left to Right Shunt.

AJP reports

Dasgupta S, Aly AM, Jain SK.
PMID: 26929880
AJP Rep. 2016 Mar;6(1):e96-8. doi: 10.1055/s-0035-1567858. Epub 2015 Nov 20.

Introduction Congestive heart failure due to left to right cardiac shunt is usually managed medically with diuretics, angiotensin converting enzyme inhibitors, and, in some cases, with the addition of digoxin. Case We report a 31-week gestation premature male infant...

Showing 1 to 3 of 3 entries