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Showing 1 to 12 of 24 entries
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A sustained high fat diet for two years decreases IgM and IL-1 beta in ageing Wistar rats.

Immunity & ageing : I & A

Pongratz G, Lowin T, Kob R, Buettner R, Bertsch T, Bollheimer LC.
PMID: 26421054
Immun Ageing. 2015 Sep 28;12:12. doi: 10.1186/s12979-015-0040-1. eCollection 2015.

BACKGROUND: The immune system undergoes several alterations of innate and adaptive immunity during ageing. The main features of the aged immune system are a reduced diversity of T cell receptors and a reduced activity of innate immune cells with...

Regulation of fc receptor endocytic trafficking by ubiquitination.

Frontiers in immunology

Molfetta R, Quatrini L, Gasparrini F, Zitti B, Santoni A, Paolini R.
PMID: 25278942
Front Immunol. 2014 Sep 18;5:449. doi: 10.3389/fimmu.2014.00449. eCollection 2014.

Most immune cells, particularly phagocytes, express various receptors for the Fc portion of the different immunoglobulin isotypes (Fc receptors, FcRs). By binding to the antibody, they provide a link between the adaptive immune system and the powerful effector functions...

Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response.

medRxiv : the preprint server for health sciences

Shields AM, Faustini SE, Perez-Toledo M, Jossi S, Allen JD, Al-Taei S, Backhouse C, Dunbar L, Ebanks D, Emmanuel B, Faniyi AA, Garvey MI, Grinbergs A, McGinnell G, O'Neill J, Watanabe Y, Crispin M, Wraith DC, Cunningham AF, Drayson MT, Richter AG.
PMID: 33236029
medRxiv. 2020 Nov 16; doi: 10.1101/2020.11.12.20230763.

OBJECTIVE: To determine clinical and ethnodemographic correlates of serological responses against the SARS-CoV-2 spike glycoprotein following mild-to-moderate COVID-19.DESIGN: A retrospective cohort study of healthcare workers who had self-isolated due to COVID-19.SETTING: University Hospitals Birmingham NHS Foundation Trust, UK (UHBFT).PARTICIPANTS:...

Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine.

Vaccines

Te Kamp V, Friedrichs V, Freuling CM, Vos A, Potratz M, Klein A, Zaeck LM, Eggerbauer E, Schuster P, Kaiser C, Ortmann S, Kretzschmar A, Bobe K, Knittler MR, Dorhoi A, Finke S, Müller T.
PMID: 33466701
Vaccines (Basel). 2021 Jan 14;9(1). doi: 10.3390/vaccines9010049.

The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of administration. Induction of...

Prediagnostic Antibody Responses to .

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Lo CH, Blot WJ, Teras LR, Visvanathan K, Le Marchand L, Haiman CA, Chen Y, Sesso HD, Wassertheil-Smoller S, Tinker LF, Peek RM, Potter JD, Cover TL, Zeleniuch-Jacquotte A, Berndt SI, Waterboer T, Epplein M, Butt J, Song M.
PMID: 33737297
Cancer Epidemiol Biomarkers Prev. 2021 Jun;30(6):1279-1282. doi: 10.1158/1055-9965.EPI-20-1471. Epub 2021 Mar 18.

BACKGROUND: The association between prediagnostic antibody responses to METHODS: We conducted a nested case-control study of 8,126 participants in a consortium of 10 prospective cohorts in the United States.RESULTS: Higher seroprevalence of any CONCLUSIONS: Prediagnostic antibody responses to IMPACT:...

Autoimmune cytopenias in common variable immunodeficiency.

Frontiers in immunology

Podjasek JC, Abraham RS.
PMID: 22837758
Front Immunol. 2012 Jul 24;3:189. doi: 10.3389/fimmu.2012.00189. eCollection 2012.

Common variable immunodeficiency (CVID) is a humoral immunodeficiency whose primary diagnostic features include hypogammaglobulinemia involving two or more immunoglobulin isotypes and impaired functional antibody responses in the majority of patients. While increased susceptibility to respiratory and other infections is...

Anti-SARS-CoV-2 Immunoglobulin Isotypes, and Neutralization Activity Against Viral Variants, According to BNT162b2-Vaccination and Infection History.

Frontiers in immunology

Tarkowski M, de Jager W, Schiuma M, Covizzi A, Lai A, Gabrieli A, Corbellino M, Bergna A, Ventura CD, Galli M, Riva A, Antinori S.
PMID: 34975897
Front Immunol. 2021 Dec 17;12:793191. doi: 10.3389/fimmu.2021.793191. eCollection 2021.

PURPOSE: To compare SARS-CoV-2 antigen-specific antibody production and plasma neutralizing capacity against B.1 wild-type-like strain, and Gamma/P.1 and Delta/B.1.617.2 variants-of-concern, in subjects with different Covid-19 disease and vaccination histories.METHODS: Adult subjects were: 1) Unvaccinated/hospitalized for Covid-19; 2) Covid-19-recovered followed...

IgG subclasses and allotypes: from structure to effector functions.

Frontiers in immunology

Vidarsson G, Dekkers G, Rispens T.
PMID: 25368619
Front Immunol. 2014 Oct 20;5:520. doi: 10.3389/fimmu.2014.00520. eCollection 2014.

Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains....

Human Colorectal Carcinoma Infiltrating B Lymphocytes Are Active Secretors of the Immunoglobulin Isotypes A, G, and M.

Cancers

Mullins CS, Gock M, Krohn M, Linnebacher M.
PMID: 31167511
Cancers (Basel). 2019 Jun 04;11(6). doi: 10.3390/cancers11060776.

Despite the importance of tumor infiltrating B cells (TiBc) in immunological circuits, their functional role is scarcely investigated. Here, we analyzed immunoglobulin (Ig) secretion of the subtypes IgA, IgG, and IgM of TiBc from freshly resected primary and secondary...

Epitope Specificity of Monoclonal Antibodies to Porcine Immunoglobulin G and Light Chains.

Russian journal of immunology : RJI : official journal of Russian Society of Immunology

Verkhovsky OA, Fedorov YN, Korotkova NN, Feoktistova TA.
PMID: 12687063
Russ J Immunol. 1997 Jul;2(2):103-110.

Monoclonal antibodies to porcine IgG and light chains were produced and characterized. The specificity of selected mAbs was revealed by their selective reactivity with porcine immunoglobulins in ELISA, immunodiffusion, immunoelectrophoresis, and immunoblot analysis. For determining the presence of different...

Modern Immunotherapy in Clinical Medicine: Present and Future.

Russian journal of immunology : RJI : official journal of Russian Society of Immunology

Nesterova IV.
PMID: 12687147
Russ J Immunol. 1999 Dec;4(4):322-326.

In this manuscript an attempt is made to review the most important information pertinent to the main immunotropic preparations used now in different fields of clinical medicine. Numerous studies have confirmed high clinico-immunological efficiency of natural and synthetic thymus...

Bacterial corneal ulcer associated with common variable immune deficiency.

Journal of ophthalmic inflammation and infection

Tsui E, Deng J, Siedlecki AN, Zegans ME.
PMID: 27491761
J Ophthalmic Inflamm Infect. 2016 Dec;6(1):28. doi: 10.1186/s12348-016-0098-8. Epub 2016 Aug 05.

Common variable immune deficiency (CVID) is one of the most commonly diagnosed primary immunodeficiencies. Generally, patients have a history of recurrent sinopulmonary infections, hypogammaglobulinemia of two or more immunoglobulin isotypes, and impaired functional antibody responses. Reports of corneal involvement...

Showing 1 to 12 of 24 entries