Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 616 entries
Sorted by: Best Match Show Resources per page
Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations.

Frontiers in immunology

Zimmermann MT, Kennedy RB, Grill DE, Oberg AL, Goergen KM, Ovsyannikova IG, Haralambieva IH, Poland GA.
PMID: 28484452
Front Immunol. 2017 Apr 21;8:445. doi: 10.3389/fimmu.2017.00445. eCollection 2017.

The development of a humoral immune response to influenza vaccines occurs on a multisystems level. Due to the orchestration required for robust immune responses when multiple genes and their regulatory components across multiple cell types are involved, we examined...

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future.

Vaccines

Trombetta CM, Perini D, Mather S, Temperton N, Montomoli E.
PMID: 26344888
Vaccines (Basel). 2014 Oct 13;2(4):707-34. doi: 10.3390/vaccines2040707.

Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays. HI and SRH are established and reproducible techniques, whereas VN is more demanding. Every new influenza vaccine...

Vaccine procurement during an influenza pandemic and the role of Advance Purchase Agreements: Lessons from 2009-H1N1.

Global public health

Turner M.
PMID: 26209064
Glob Public Health. 2016 Mar;11(3):322-335. doi: 10.1080/17441692.2015.1043743. Epub 2015 Jul 24.

Vaccines are hugely important tools in minimising the effect pandemic influenza could have on a population. The reforms introduced by the Pandemic Influenza Preparedness Framework are ill-suited to providing sufficient levels of access to vaccines to meet the needs...

Antibody Immunity Induced by H7N9 Avian Influenza Vaccines: Evaluation Criteria, Affecting Factors, and Implications for Rational Vaccine Design.

Frontiers in microbiology

Hu Z, Jiao X, Liu X.
PMID: 29018438
Front Microbiol. 2017 Sep 26;8:1898. doi: 10.3389/fmicb.2017.01898. eCollection 2017.

Severe H7N9 avian influenza virus (AIV) infections in humans have public health authorities around the world on high alert for the potential development of a human influenza pandemic. Currently, the newly-emerged highly pathogenic avian influenza A (H7N9) virus poses...

Adjuvant effect of cationic liposomes for subunit influenza vaccine: influence of antigen loading method, cholesterol and immune modulators.

Pharmaceutics

Barnier-Quer C, Elsharkawy A, Romeijn S, Kros A, Jiskoot W.
PMID: 24300513
Pharmaceutics. 2013 Jul 25;5(3):392-410. doi: 10.3390/pharmaceutics5030392.

Cationic liposomes are potential adjuvants for influenza vaccines. In a previous study we reported that among a panel of cationic liposomes loaded with influenza hemagglutinin (HA), DC-Chol:DPPC (1:1 molar ratio) liposomes induced the strongest immune response. However, it is...

Age-Specific Patterns of Influenza Activity in Utah: Do Older School Age Children Drive the Epidemic?.

Journal of the Pediatric Infectious Diseases Society

Stockmann C, Pavia AT, Hersh AL, Spigarelli MG, Castle B, Korgenski K, Byington CL, Ampofo K.
PMID: 24872880
J Pediatric Infect Dis Soc. 2014 Jun;3(2):163-7. doi: 10.1093/jpids/pit004. Epub 2013 Feb 14.

Across 12 consecutive influenza seasons in Utah, medically-attended visits for laboratory-confirmed influenza infection peaked first among older children (12-18 years). Peak activity in older children preceded that of children 0-4 years by more than 2 days and that of...

Zoonotic infections with avian influenza A viruses and vaccine preparedness: a game of "mix and match".

Clinical and experimental vaccine research

Pascua PN, Choi YK.
PMID: 25003087
Clin Exp Vaccine Res. 2014 Jul;3(2):140-8. doi: 10.7774/cevr.2014.3.2.140. Epub 2014 Jun 20.

Various direct avian-to-human transmissions of influenza A virus subtypes upon exposure to infected poultry have been previously observed in the past decades. Although some of these strains caused lethal infections, the lack of sustained person-to-person transmission has been the...

The benefits of influenza vaccine in pregnancy for the fetus and the infant younger than six months of age.

Paediatrics & child health

MacDonald NE, McDonald JC.
PMID: 25587237
Paediatr Child Health. 2014 Dec;19(10):e121-2.

Influenza is a serious problem for infants

A Novel Dynamic Model for Health Economic Analysis of Influenza Vaccination in the Elderly.

Infectious diseases and therapy

Mullikin M, Tan L, Jansen JP, Van Ranst M, Farkas N, Petri E.
PMID: 26350238
Infect Dis Ther. 2015 Dec;4(4):459-87. doi: 10.1007/s40121-015-0076-8. Epub 2015 Sep 09.

INTRODUCTION: New vaccines are being developed to improve the efficacy of seasonal influenza immunization in elderly persons aged ≥65 years. These products require clinical and economic evaluation to aid policy decisions.METHODS: To address this need, a two-part model has...

Influenza vaccination in the elderly: why are the overall benefits still hotly debated?.

Journal of preventive medicine and hygiene

Trucchi C, Paganino C, Orsi A, De Florentiis D, Ansaldi F.
PMID: 26789831
J Prev Med Hyg. 2015 Jun 10;56(1):E37-43.

The exact magnitude of the benefit of influenza vaccine among elderly individuals is subject of considerable debated. Existing vaccine effectiveness estimates come mostly from observational studies, which may be biased because of difficulties in identifying and adjusting for confounders....

Do Athletes Need Influenza Vaccines?.

The Physician and sportsmedicine

Johnson CC.
PMID: 27447587
Phys Sportsmed. 1990 Sep;18(9):80-4. doi: 10.1080/00913847.1990.11710137.

A bout of influenza can lay anyone low. For an athlete, it can mean losing valuable practice and playing time and may diminish a team's competitive edge. Still, many team physicians lay out the facts and let athletes make...

Comparison of serum hemagglutinin and neuraminidase inhibition antibodies after 2010-2011 trivalent inactivated influenza vaccination in healthcare personnel.

Open forum infectious diseases

Laguio-Vila MR, Thompson MG, Reynolds S, Spencer SM, Gaglani M, Naleway A, Ball S, Bozeman S, Baker S, Martínez-Sobrido L, Levine M, Katz J, Fry AM, Treanor JJ.
PMID: 25884004
Open Forum Infect Dis. 2015 Jan 03;2(1):ofu115. doi: 10.1093/ofid/ofu115. eCollection 2015 Jan.

Background.  Most inactivated influenza vaccines contain purified and standardized hemagglutinin (HA) and residual neuraminidase (NA) antigens. Vaccine-associated HA antibody responses (hemagglutination inhibition [HAI]) are well described, but less is known about the immune response to the NA. Methods.  Serum...

Showing 1 to 12 of 616 entries