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Showing 1 to 12 of 147 entries
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A study of bone mineral density and its determinants in type 1 diabetes mellitus.

Journal of osteoporosis

Joshi A, Varthakavi P, Chadha M, Bhagwat N.
PMID: 23607045
J Osteoporos. 2013;2013:397814. doi: 10.1155/2013/397814. Epub 2013 Mar 31.

Type 1 diabetes mellitus (T1DM) has been inconsistently associated with low bone mineral density (BMD) and increased fracture risk. 86 consecutive T1DM cases and 140 unrelated age and sex matched healthy nondiabetic controls were included in the study. After...

Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer.

OncoTargets and therapy

Wang Z, Wang Z, Liang Z, Liu J, Shi W, Bai P, Lin X, Magaye R, Zhao J.
PMID: 24204158
Onco Targets Ther. 2013 Oct 16;6:1437-44. doi: 10.2147/OTT.S51997. eCollection 2013.

The expression and clinical significance of insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3), and insulin-like growth factor binding protein 7 (IGFBP-7) were investigated in serum and lung cancer tissues from 57 patients with non-small...

Cloning and expression of full-length human insulin-like growth factor binding protein 3 (IGFBP3) in the Escherichia coli.

Advanced biomedical research

Khodadadi E, Panjepour M, Abbasian M, Broujeni ZK, Mofid MR.
PMID: 25878991
Adv Biomed Res. 2015 Mar 25;4:66. doi: 10.4103/2277-9175.153886. eCollection 2015.

BACKGROUND: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids. Considering the important application of...

Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors.

Oncology letters

Niinuma T, Kai M, Kitajima H, Yamamoto E, Harada T, Maruyama R, Nobuoka T, Nishida T, Kanda T, Hasegawa T, Tokino T, Sugai T, Shinomura Y, Nakase H, Suzuki H.
PMID: 29113198
Oncol Lett. 2017 Nov;14(5):5703-5710. doi: 10.3892/ol.2017.6911. Epub 2017 Sep 08.

Although dysregulation of microRNAs (miRNAs/miRs) is a common feature of human malignancies, its involvement in gastrointestinal stromal tumors (GISTs) is not fully understood. The present study aimed to identify the miRNAs that perform a role in GIST metastasis. miRNA...

Insulin, insulin-like growth factor 1 and insulin-like growth factor binding protein 3 serum concentrations in patients with adenomatous colon polyps.

Przeglad gastroenterologiczny

Janiak A, Oset P, Talar-Wojnarowska R, Kumor A, Małecka-Panas E.
PMID: 24868275
Prz Gastroenterol. 2013;8(5):308-14. doi: 10.5114/pg.2013.38734. Epub 2013 Oct 28.

INTRODUCTION: Insulin stimulates colonic mucosal cells proliferation directly and by influencing the concentration of insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3).AIM: To estimate serum concentrations of insulin, IGF-1, and IGFBP-3 and to determine...

Correction: ADAM28 Is Overexpressed in Human Breast Carcinomas: Implications for Carcinoma Cell Proliferation through Cleavage of Insulin-like Growth Factor Binding Protein-3.

Cancer research

[No authors listed]
PMID: 26471916
Cancer Res. 2015 Oct 15;75(20):4437-8. doi: 10.1158/0008-5472.CAN-15-2369.

No abstract available.

Detection and correlation analysis of serum cytokines in non-small-cell lung cancer patients with bone and non-bone metastases.

Patient preference and adherence

Sun Y, Ai X, Shen S, Gu L, Lu S.
PMID: 26316721
Patient Prefer Adherence. 2015 Aug 12;9:1165-9. doi: 10.2147/PPA.S86605. eCollection 2015.

OBJECTIVE: To detect and analyze 13 cytokines that may be related to bone metastasis in the serum of non-small-cell lung cancer (NSCLC) patients with bone metastases and NSCLC patients with non-bone metastases.PATIENTS AND METHODS: The Luminex LiquiChip system was...

Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus.

Annals of pediatric endocrinology & metabolism

Kim MS, Lee DY.
PMID: 26191509
Ann Pediatr Endocrinol Metab. 2015 Jun;20(2):69-73. doi: 10.6065/apem.2015.20.2.69. Epub 2015 Jun 30.

Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response to the diabetic milieu....

Circulating insulin-like growth factor-binding protein 3 as prognostic biomarker in liver cirrhosis.

World journal of hepatology

Correa CG, Colombo Bda S, Ronsoni MF, Soares E Silva PE, Fayad L, Silva TE, Wildner LM, Bazzo ML, Dantas-Correa EB, Narciso-Schiavon JL, Schiavon Lde L.
PMID: 27330683
World J Hepatol. 2016 Jun 18;8(17):739-48. doi: 10.4254/wjh.v8.i17.739.

AIM: To investigate the prognostic significance of insulin-like growth factor-binding protein 3 (IGFBP-3) in patients with cirrhosis.METHODS: Prospective study that included two cohorts: outpatients with stable cirrhosis (n = 138) and patients hospitalized for acute decompensation (n = 189)....

An Evaluation of Growth Hormone and IGF-1 Responses in Neonates with Hyperinsulinaemic Hypoglycaemia.

International journal of endocrinology

Senniappan S, Hussain K.
PMID: 24228030
Int J Endocrinol. 2013;2013:638257. doi: 10.1155/2013/638257. Epub 2013 Oct 08.

Background. Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of severe and persistent hypoglycemia in the neonatal period. It has been shown that the neonates with HH fail to generate adequate serum cortisol counterregulatory response to symptomatic hypoglycemia. However...

Insulin-like growth factor-binding protein-3 is associated with the presence and extent of coronary arteriosclerosis.

Arteriosclerosis, thrombosis, and vascular biology

Schuler-Luttmann S, Monnig G, Enbergs A, Schulte H, Breithardt G, Assmann G, Kerber S, von Eckardstein A.
PMID: 10764692
Arterioscler Thromb Vasc Biol. 2000 Apr;20(4):E10-5.

Aging is associated with the progression of arteriosclerosis and the decline of several endocrine functions. We therefore investigated the association of coronary arteriosclerosis with hormones, the serum concentrations of which change during aging. Coronary angiograms of 189 men /=1...

Deep depletion of abundant serum proteins reveals low-abundant proteins as potential biomarkers for human ovarian cancer.

Proteomics. Clinical applications

Lin B, White JT, Wu J, Lele S, Old LJ, Hood L, Odunsi K.
PMID: 20559449
Proteomics Clin Appl. 2009 Jul 01;3(7):853-861. doi: 10.1002/prca.200800141.

Epithelial ovarian cancer (EOC) ranks fifth as a cause of cancer deaths in women. Current diagnostic and monitoring markers have limited reliability for the detection of disease. We have tested the possibility of identifying candidate biomarkers present at low...

Showing 1 to 12 of 147 entries