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Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation.

mSystems

Noecker C, Eng A, Srinivasan S, Theriot CM, Young VB, Jansson JK, Fredricks DN, Borenstein E.
PMID: 27239563
mSystems. 2016 Jan-Feb;1(1). doi: 10.1128/mSystems.00013-15. Epub 2016 Jan 19.

Multiple molecular assays now enable high-throughput profiling of the ecology, metabolic capacity, and activity of the human microbiome. However, to date, analyses of such multi-omic data typically focus on statistical associations, often ignoring extensive prior knowledge of the mechanisms...

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Noecker C, Eng A, Srinivasan S, et al. Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation. mSystems. 2016;1(1)doi: 10.1128/mSystems.00013-15.
Noecker, C., Eng, A., Srinivasan, S., Theriot, C. M., Young, V. B., Jansson, J. K., Fredricks, D. N., & Borenstein, E. (2016). Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation. mSystems, 1(1), . https://doi.org/10.1128/mSystems.00013-15
Noecker, Cecilia, et al. "Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation." mSystems vol. 1,1 (2016). doi: https://doi.org/10.1128/mSystems.00013-15
Noecker C, Eng A, Srinivasan S, Theriot CM, Young VB, Jansson JK, Fredricks DN, Borenstein E. Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation. mSystems. 2016 Jan-Feb;1(1). doi: 10.1128/mSystems.00013-15. Epub 2016 Jan 19. PMID: 27239563; PMCID: PMC4883586.
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Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine.

mSphere

Theriot CM, Bowman AA, Young VB.
PMID: 27239562
mSphere. 2016 Jan 06;1(1). doi: 10.1128/mSphere.00045-15. eCollection 2016.

It is hypothesized that the depletion of microbial members responsible for converting primary bile acids into secondary bile acids reduces resistance to Clostridium difficile colonization. To date, inhibition of C. difficile growth by secondary bile acids has only been...

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Theriot CM, Bowman AA, Young VB. Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere. 2016;1(1)doi: 10.1128/mSphere.00045-15.
Theriot, C. M., Bowman, A. A., & Young, V. B. (2016). Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere, 1(1), . https://doi.org/10.1128/mSphere.00045-15
Theriot, Casey M, et al. "Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine." mSphere vol. 1,1 (2016). doi: https://doi.org/10.1128/mSphere.00045-15
Theriot CM, Bowman AA, Young VB. Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine. mSphere. 2016 Jan 06;1(1). doi: 10.1128/mSphere.00045-15. eCollection 2016. PMID: 27239562; PMCID: PMC4863611.
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Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics.

mSystems

Theriot CM.
PMID: 29556548
mSystems. 2018 Mar 06;3(2). doi: 10.1128/mSystems.00173-17. eCollection 2018.

Over the past 10 years, microbiome research has focused on defining the structures associated with different disease states in multiple systems, but has fallen short on showing causation. Prior omic studies have generated many new hypotheses, but moving forward...

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Theriot CM. Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics. mSystems. 2018;3(2)doi: 10.1128/mSystems.00173-17.
Theriot, C. M. (2018). Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics. mSystems, 3(2), . https://doi.org/10.1128/mSystems.00173-17
Theriot, Casey M. "Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics." mSystems vol. 3,2 (2018). doi: https://doi.org/10.1128/mSystems.00173-17
Theriot CM. Beyond Structure: Defining the Function of the Gut Using Omic Approaches for Rational Design of Personalized Therapeutics. mSystems. 2018 Mar 06;3(2). doi: 10.1128/mSystems.00173-17. eCollection 2018. PMID: 29556548; PMCID: PMC5853185.
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Showing 1 to 3 of 3 entries