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Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U.
PMID: 32651213
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10.

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAID) is associated with lower risk of colorectal cancer. Genome-wide interaction analysis on single variants (G × E) has identified several SNPs that may interact with NSAIDs to confer colorectal cancer risk,...

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Wang X, Su YR, Petersen PS, et al. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020;29(9):1800-1808doi: 10.1158/1055-9965.EPI-19-1018.
Wang, X., Su, Y. R., Petersen, P. S., Bien, S., Schmit, S. L., Drew, D. A., Albanes, D., Berndt, S. I., Brenner, H., Campbell, P. T., Casey, G., Chang-Claude, J., Gallinger, S. J., Gruber, S. B., Haile, R. W., Harrison, T. A., Hoffmeister, M., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Li, L., Lin, Y., Lindor, N. M., Marchand, L. L., Martin, V., Milne, R., Maclnnis, R., Moreno, V., Nan, H., Newcomb, P. A., Potter, J. D., Rennert, G., Rennert, H., Slattery, M. L., Thibodeau, S. N., Weinstein, S. J., Woods, M. O., Chan, A. T., White, E., Hsu, L., & Peters, U. (2020). Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(9), 1800-1808. https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang, Xiaoliang, et al. "Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 29,9 (2020): 1800-1808. doi: https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10. PMID: 32651213; PMCID: PMC7556991.
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Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3).

International journal of epidemiology

Townsend MK, Trabert B, Fortner RT, Arslan AA, Buring JE, Carter BD, Giles GG, Irvin SR, Jones ME, Kaaks R, Kirsh VA, Knutsen SF, Koh WP, Lacey JV, Langseth H, Larsson SC, Lee IM, Martínez ME, Merritt MA, Milne RL, O'Brien KM, Orlich MJ, Palmer JR, Patel AV, Peters U, Poynter JN, Robien K, Rohan TE, Rosenberg L, Sandin S, Sandler DP, Schouten LJ, Setiawan VW, Swerdlow AJ, Ursin G, van den Brandt PA, Visvanathan K, Weiderpass E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Tworoger SS, Wentzensen N.
PMID: 34652432
Int J Epidemiol. 2021 Oct 15; doi: 10.1093/ije/dyab211. Epub 2021 Oct 15.

No abstract available.

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Townsend MK, Trabert B, Fortner RT, et al. Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3). Int J Epidemiol. 2021;doi: 10.1093/ije/dyab211.
Townsend, M. K., Trabert, B., Fortner, R. T., Arslan, A. A., Buring, J. E., Carter, B. D., Giles, G. G., Irvin, S. R., Jones, M. E., Kaaks, R., Kirsh, V. A., Knutsen, S. F., Koh, W. P., Lacey, J. V., Langseth, H., Larsson, S. C., Lee, I. M., Martínez, M. E., Merritt, M. A., Milne, R. L., O'Brien, K. M., Orlich, M. J., Palmer, J. R., Patel, A. V., Peters, U., Poynter, J. N., Robien, K., Rohan, T. E., Rosenberg, L., Sandin, S., Sandler, D. P., Schouten, L. J., Setiawan, V. W., Swerdlow, A. J., Ursin, G., van den Brandt, P. A., Visvanathan, K., Weiderpass, E., Wolk, A., Yuan, J. M., Zeleniuch-Jacquotte, A., Tworoger, S. S., & Wentzensen, N. (2021). Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3). International journal of epidemiology, . https://doi.org/10.1093/ije/dyab211
Townsend, Mary K, et al. "Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3)." International journal of epidemiology vol. (2021). doi: https://doi.org/10.1093/ije/dyab211
Townsend MK, Trabert B, Fortner RT, Arslan AA, Buring JE, Carter BD, Giles GG, Irvin SR, Jones ME, Kaaks R, Kirsh VA, Knutsen SF, Koh WP, Lacey JV, Langseth H, Larsson SC, Lee IM, Martínez ME, Merritt MA, Milne RL, O'Brien KM, Orlich MJ, Palmer JR, Patel AV, Peters U, Poynter JN, Robien K, Rohan TE, Rosenberg L, Sandin S, Sandler DP, Schouten LJ, Setiawan VW, Swerdlow AJ, Ursin G, van den Brandt PA, Visvanathan K, Weiderpass E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Tworoger SS, Wentzensen N. Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3). Int J Epidemiol. 2021 Oct 15; doi: 10.1093/ije/dyab211. Epub 2021 Oct 15. PMID: 34652432.
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Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Fortner RT, Rice MS, Knutsen SF, Orlich MJ, Visvanathan K, Patel AV, Gaudet MM, Tjønneland A, Kvaskoff M, Kaaks R, Trichopolou A, Pala V, Onland-Moret NC, Gram IT, Amiano P, Idahl A, Allen NE, Weiderpass E, Poynter JN, Robien K, Giles GG, Milne RL, Setiawan VW, Merritt MA, van den Brandt PA, Zeleniuch-Jacquotte A, Arslan AA, O'Brien KM, Sandler DP, Wolk A, Håkansson N, Harris HR, Trabert B, Wentzensen N, Tworoger SS, Schouten LJ.
PMID: 32732252
Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):2010-2018. doi: 10.1158/1055-9965.EPI-20-0354. Epub 2020 Jul 30.

BACKGROUND: Epithelial ovarian, fallopian tube, and primary peritoneal cancers have shared developmental pathways. Few studies have prospectively examined heterogeneity in risk factor associations across these three anatomic sites.METHODS: We identified 3,738 ovarian, 337 peritoneal, and 176 fallopian tube incident...

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Fortner RT, Rice MS, Knutsen SF, et al. Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev. 2020;29(10):2010-2018doi: 10.1158/1055-9965.EPI-20-0354.
Fortner, R. T., Rice, M. S., Knutsen, S. F., Orlich, M. J., Visvanathan, K., Patel, A. V., Gaudet, M. M., Tjønneland, A., Kvaskoff, M., Kaaks, R., Trichopolou, A., Pala, V., Onland-Moret, N. C., Gram, I. T., Amiano, P., Idahl, A., Allen, N. E., Weiderpass, E., Poynter, J. N., Robien, K., Giles, G. G., Milne, R. L., Setiawan, V. W., Merritt, M. A., van den Brandt, P. A., Zeleniuch-Jacquotte, A., Arslan, A. A., O'Brien, K. M., Sandler, D. P., Wolk, A., Håkansson, N., Harris, H. R., Trabert, B., Wentzensen, N., Tworoger, S. S., & Schouten, L. J. (2020). Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(10), 2010-2018. https://doi.org/10.1158/1055-9965.EPI-20-0354
Fortner, Renée T, et al. "Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 29,10 (2020): 2010-2018. doi: https://doi.org/10.1158/1055-9965.EPI-20-0354
Fortner RT, Rice MS, Knutsen SF, Orlich MJ, Visvanathan K, Patel AV, Gaudet MM, Tjønneland A, Kvaskoff M, Kaaks R, Trichopolou A, Pala V, Onland-Moret NC, Gram IT, Amiano P, Idahl A, Allen NE, Weiderpass E, Poynter JN, Robien K, Giles GG, Milne RL, Setiawan VW, Merritt MA, van den Brandt PA, Zeleniuch-Jacquotte A, Arslan AA, O'Brien KM, Sandler DP, Wolk A, Håkansson N, Harris HR, Trabert B, Wentzensen N, Tworoger SS, Schouten LJ. Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):2010-2018. doi: 10.1158/1055-9965.EPI-20-0354. Epub 2020 Jul 30. PMID: 32732252; PMCID: PMC7541500.
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Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia.

International journal of molecular epidemiology and genetics

Abbenhardt C, Poole EM, Kulmacz RJ, Xiao L, Curtin K, Galbraith RL, Duggan D, Hsu L, Makar KW, Caan BJ, Koepl L, Owen RW, Scherer D, Carlson CS, Potter JD, Slattery ML, Ulrich CM.
PMID: 24046806
Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):140-9. eCollection 2013.

Pancreatic phospholipase A2, product of PLA2G1B, catalyzes the release of fatty acids from dietary phospholipids.Diet is the ultimate source of arachidonic acid in cellular phospholipids, precursor of eicosanoid signaling molecules, linked to inflammation, cell proliferation and colorectal carcinogenesis. We...

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Abbenhardt C, Poole EM, Kulmacz RJ, et al. Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia. Int J Mol Epidemiol Genet. 2013;4(3):140-9
Abbenhardt, C., Poole, E. M., Kulmacz, R. J., Xiao, L., Curtin, K., Galbraith, R. L., Duggan, D., Hsu, L., Makar, K. W., Caan, B. J., Koepl, L., Owen, R. W., Scherer, D., Carlson, C. S., Potter, J. D., Slattery, M. L., & Ulrich, C. M. (2013). Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia. International journal of molecular epidemiology and genetics, 4(3), 140-9.
Abbenhardt, Clare, et al. "Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia." International journal of molecular epidemiology and genetics vol. 4,3 (2013): 140-9.
Abbenhardt C, Poole EM, Kulmacz RJ, Xiao L, Curtin K, Galbraith RL, Duggan D, Hsu L, Makar KW, Caan BJ, Koepl L, Owen RW, Scherer D, Carlson CS, Potter JD, Slattery ML, Ulrich CM. Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia. Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):140-9. eCollection 2013. PMID: 24046806; PMCID: PMC3773565.
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Identifying Persons at Highest Risk of Melanoma Using Self-Assessed Risk Factors.

Journal of clinical & experimental dermatology research

Williams LH, Shors AR, Barlow WE, Solomon C, White E.
PMID: 22229112
J Clin Exp Dermatol Res. 2011;2(6). doi: 10.4172/2155-9554.1000129.

OBJECTIVE: To develop a self-assessed melanoma risk score to identify high-risk persons for screening METHODS: We used data from a 1997 melanoma case-control study from Washington State, USA, where 386 cases with invasive cutaneous melanoma and 727 controls were...

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Williams LH, Shors AR, Barlow WE, et al. Identifying Persons at Highest Risk of Melanoma Using Self-Assessed Risk Factors. J Clin Exp Dermatol Res. 2011;2(6)doi: 10.4172/2155-9554.1000129.
Williams, L. H., Shors, A. R., Barlow, W. E., Solomon, C., & White, E. (2011). Identifying Persons at Highest Risk of Melanoma Using Self-Assessed Risk Factors. Journal of clinical & experimental dermatology research, 2(6), . https://doi.org/10.4172/2155-9554.1000129
Williams, Lisa H, et al. "Identifying Persons at Highest Risk of Melanoma Using Self-Assessed Risk Factors." Journal of clinical & experimental dermatology research vol. 2,6 (2011). doi: https://doi.org/10.4172/2155-9554.1000129
Williams LH, Shors AR, Barlow WE, Solomon C, White E. Identifying Persons at Highest Risk of Melanoma Using Self-Assessed Risk Factors. J Clin Exp Dermatol Res. 2011;2(6). doi: 10.4172/2155-9554.1000129. PMID: 22229112; PMCID: PMC3252382.
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Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Yin H, Hardikar S, Lindstroem S, Hsu L, Anderson KE, Banbury BL, Berndt SI, Chan AT, Giovanucci EL, Harrison TA, Joshi AD, Nan H, Potter JD, Sakoda LC, Slattery ML, Schoen RE, White E, Peters U, Newcomb PA.
PMID: 32586834
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1817-1824. doi: 10.1158/1055-9965.EPI-19-1507. Epub 2020 Jun 25.

BACKGROUND: Telomeres play an important role in colorectal cancer prognosis. Variation in telomere maintenance genes may be associated with survival after colorectal cancer diagnosis, but evidence is limited. In addition, possible interactions between telomere maintenance genes and prognostic factors,...

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Yin H, Hardikar S, Lindstroem S, et al. Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations. Cancer Epidemiol Biomarkers Prev. 2020;29(9):1817-1824doi: 10.1158/1055-9965.EPI-19-1507.
Yin, H., Hardikar, S., Lindstroem, S., Hsu, L., Anderson, K. E., Banbury, B. L., Berndt, S. I., Chan, A. T., Giovanucci, E. L., Harrison, T. A., Joshi, A. D., Nan, H., Potter, J. D., Sakoda, L. C., Slattery, M. L., Schoen, R. E., White, E., Peters, U., & Newcomb, P. A. (2020). Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(9), 1817-1824. https://doi.org/10.1158/1055-9965.EPI-19-1507
Yin, Hang, et al. "Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 29,9 (2020): 1817-1824. doi: https://doi.org/10.1158/1055-9965.EPI-19-1507
Yin H, Hardikar S, Lindstroem S, Hsu L, Anderson KE, Banbury BL, Berndt SI, Chan AT, Giovanucci EL, Harrison TA, Joshi AD, Nan H, Potter JD, Sakoda LC, Slattery ML, Schoen RE, White E, Peters U, Newcomb PA. Telomere Maintenance Variants and Survival after Colorectal Cancer: Smoking- and Sex-Specific Associations. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1817-1824. doi: 10.1158/1055-9965.EPI-19-1507. Epub 2020 Jun 25. PMID: 32586834; PMCID: PMC7928192.
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A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Nounu A, Greenhough A, Heesom KJ, Richmond RC, Zheng J, Weinstein SJ, Albanes D, Baron JA, Hopper JL, Figueiredo JC, Newcomb PA, Lindor NM, Casey G, Platz EA, Le Marchand L, Ulrich CM, Li CI, van Duijnhoven FJB, Gsur A, Campbell PT, Moreno V, Vodicka P, Vodickova L, Brenner H, Chang-Claude J, Hoffmeister M, Sakoda LC, Slattery ML, Schoen RE, Gunter MJ, Castellví-Bel S, Kim HR, Kweon SS, Chan AT, Li L, Zheng W, Bishop DT, Buchanan DD, Giles GG, Gruber SB, Rennert G, Stadler ZK, Harrison TA, Lin Y, Keku TO, Woods MO, Schafmayer C, Van Guelpen B, Gallinger S, Hampel H, Berndt SI, Pharoah PDP, Lindblom A, Wolk A, Wu AH, White E, Peters U, Drew DA, Scherer D, Bermejo JL, Williams AC, Relton CL.
PMID: 33318029
Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):564-575. doi: 10.1158/1055-9965.EPI-20-1176. Epub 2020 Dec 14.

BACKGROUND: Evidence for aspirin's chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new aspirin targets that decrease CRC risk.METHODS:...

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Nounu A, Greenhough A, Heesom KJ, et al. A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2020;30(3):564-575doi: 10.1158/1055-9965.EPI-20-1176.
Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., Albanes, D., Baron, J. A., Hopper, J. L., Figueiredo, J. C., Newcomb, P. A., Lindor, N. M., Casey, G., Platz, E. A., Le Marchand, L., Ulrich, C. M., Li, C. I., van Duijnhoven, F. J. B., Gsur, A., Campbell, P. T., Moreno, V., Vodicka, P., Vodickova, L., Brenner, H., Chang-Claude, J., Hoffmeister, M., Sakoda, L. C., Slattery, M. L., Schoen, R. E., Gunter, M. J., Castellví-Bel, S., Kim, H. R., Kweon, S. S., Chan, A. T., Li, L., Zheng, W., Bishop, D. T., Buchanan, D. D., Giles, G. G., Gruber, S. B., Rennert, G., Stadler, Z. K., Harrison, T. A., Lin, Y., Keku, T. O., Woods, M. O., Schafmayer, C., Van Guelpen, B., Gallinger, S., Hampel, H., Berndt, S. I., Pharoah, P. D. P., Lindblom, A., Wolk, A., Wu, A. H., White, E., Peters, U., Drew, D. A., Scherer, D., Bermejo, J. L., Williams, A. C., & Relton, C. L. (2021). A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(3), 564-575. https://doi.org/10.1158/1055-9965.EPI-20-1176
Nounu, Aayah, et al. "A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,3 (2021): 564-575. doi: https://doi.org/10.1158/1055-9965.EPI-20-1176
Nounu A, Greenhough A, Heesom KJ, Richmond RC, Zheng J, Weinstein SJ, Albanes D, Baron JA, Hopper JL, Figueiredo JC, Newcomb PA, Lindor NM, Casey G, Platz EA, Le Marchand L, Ulrich CM, Li CI, van Duijnhoven FJB, Gsur A, Campbell PT, Moreno V, Vodicka P, Vodickova L, Brenner H, Chang-Claude J, Hoffmeister M, Sakoda LC, Slattery ML, Schoen RE, Gunter MJ, Castellví-Bel S, Kim HR, Kweon SS, Chan AT, Li L, Zheng W, Bishop DT, Buchanan DD, Giles GG, Gruber SB, Rennert G, Stadler ZK, Harrison TA, Lin Y, Keku TO, Woods MO, Schafmayer C, Van Guelpen B, Gallinger S, Hampel H, Berndt SI, Pharoah PDP, Lindblom A, Wolk A, Wu AH, White E, Peters U, Drew DA, Scherer D, Bermejo JL, Williams AC, Relton CL. A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):564-575. doi: 10.1158/1055-9965.EPI-20-1176. Epub 2020 Dec 14. PMID: 33318029; PMCID: PMC8086774.
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Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA.
PMID: 33972368
Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1349-1358. doi: 10.1158/1055-9965.EPI-20-1848. Epub 2021 May 10.

BACKGROUND: A positive association between circulating C-reactive protein (CRP) and colorectal cancer survival was reported in observational studies, which are susceptible to unmeasured confounding and reverse causality. We used a Mendelian randomization approach to evaluate the association between genetically...

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Hua X, Dai JY, Lindström S, et al. Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer Epidemiol Biomarkers Prev. 2021;30(7):1349-1358doi: 10.1158/1055-9965.EPI-20-1848.
Hua, X., Dai, J. Y., Lindström, S., Harrison, T. A., Lin, Y., Alberts, S. R., Alwers, E., Berndt, S. I., Brenner, H., Buchanan, D. D., Campbell, P. T., Casey, G., Chang-Claude, J., Gallinger, S., Giles, G. G., Goldberg, R. M., Gunter, M. J., Hoffmeister, M., Jenkins, M. A., Joshi, A. D., Ma, W., Milne, R. L., Murphy, N., Pai, R. K., Sakoda, L. C., Schoen, R. E., Shi, Q., Slattery, M. L., Song, M., White, E., Marchand, L. L., Chan, A. T., Peters, U., & Newcomb, P. A. (2021). Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(7), 1349-1358. https://doi.org/10.1158/1055-9965.EPI-20-1848
Hua, Xinwei, et al. "Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,7 (2021): 1349-1358. doi: https://doi.org/10.1158/1055-9965.EPI-20-1848
Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA. Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1349-1358. doi: 10.1158/1055-9965.EPI-20-1848. Epub 2021 May 10. PMID: 33972368; PMCID: PMC8254760.
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Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Dimou N, Yarmolinsky J, Bouras E, Tsilidis KK, Martin RM, Lewis SJ, Gram IT, Bakker MF, Brenner H, Figueiredo JC, Fortner RT, Gruber SB, van Guelpen B, Hsu L, Kaaks R, Kweon SS, Lin Y, Lindor NM, Newcomb PA, Sánchez MJ, Severi G, Tindle HA, Tumino R, Weiderpass E, Gunter MJ, Murphy N.
PMID: 33653810
Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):953-964. doi: 10.1158/1055-9965.EPI-20-1218. Epub 2021 Mar 02.

BACKGROUND: Observational evidence has shown that smoking is a risk factor for breast and colorectal cancer. We used Mendelian randomization (MR) to examine causal associations between smoking and risks of breast and colorectal cancer.METHODS: Genome-Wide Association Study summary data...

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Dimou N, Yarmolinsky J, Bouras E, et al. Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study. Cancer Epidemiol Biomarkers Prev. 2021;30(5):953-964doi: 10.1158/1055-9965.EPI-20-1218.
Dimou, N., Yarmolinsky, J., Bouras, E., Tsilidis, K. K., Martin, R. M., Lewis, S. J., Gram, I. T., Bakker, M. F., Brenner, H., Figueiredo, J. C., Fortner, R. T., Gruber, S. B., van Guelpen, B., Hsu, L., Kaaks, R., Kweon, S. S., Lin, Y., Lindor, N. M., Newcomb, P. A., Sánchez, M. J., Severi, G., Tindle, H. A., Tumino, R., Weiderpass, E., Gunter, M. J., & Murphy, N. (2021). Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(5), 953-964. https://doi.org/10.1158/1055-9965.EPI-20-1218
Dimou, Niki, et al. "Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,5 (2021): 953-964. doi: https://doi.org/10.1158/1055-9965.EPI-20-1218
Dimou N, Yarmolinsky J, Bouras E, Tsilidis KK, Martin RM, Lewis SJ, Gram IT, Bakker MF, Brenner H, Figueiredo JC, Fortner RT, Gruber SB, van Guelpen B, Hsu L, Kaaks R, Kweon SS, Lin Y, Lindor NM, Newcomb PA, Sánchez MJ, Severi G, Tindle HA, Tumino R, Weiderpass E, Gunter MJ, Murphy N. Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study. Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):953-964. doi: 10.1158/1055-9965.EPI-20-1218. Epub 2021 Mar 02. PMID: 33653810; PMCID: PMC7611442.
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