International journal of nephrology and renovascular disease

Zhang Y, Corapi KM, Luongo M, Thadhani R, Nigwekar SU.
PMID: 27698566
Int J Nephrol Renovasc Dis. 2016 Sep 19;9:235-241. doi: 10.2147/IJNRD.S115701. eCollection 2016.

BACKGROUND: Calciphylaxis is a rare but devastating condition in end-stage renal disease (ESRD) patients. Most research in the field of calciphylaxis is focused on hemodialysis (HD) patients; however, data on calciphylaxis incidence, risk factors, and mortality in peritoneal dialysis...

International journal of nephrology

Allegretti AS, Ortiz G, Wenger J, Deferio JJ, Wibecan J, Kalim S, Tamez H, Chung RT, Karumanchi SA, Thadhani RI.
PMID: 26266048
Int J Nephrol. 2015;2015:108139. doi: 10.1155/2015/108139. Epub 2015 Jul 22.

Background/Aims. Acute kidney injury is a common problem for patients with cirrhosis and is associated with poor survival. We aimed to examine the association between type of acute kidney injury and 90-day mortality. Methods. Prospective cohort study at a...

Journal of acquired immune deficiency syndromes (1999)

Chan BT, Tsai AC.
PMID: 28399046
J Acquir Immune Defic Syndr. 2017 May 01;75(1):e21-e22. doi: 10.1097/QAI.0000000000001214.

No abstract available.

Journal of health disparities research and practice

Kiely DK, Kim DH, Gross AL, Habtemariam DA, Leveille SG, Li W, Lipsitz LA.
PMID: 26855845
J Health Dispar Res Pract. 2015;8(3):72-84.

OBJECTIVE: To determine whether previously reported racial differences in fall rates between White and Black/African American is explained by differences in health status and neighborhood characteristics.DESIGN: Prospective cohort.SETTING: Community.PARTICIPANTS: The study included 550 White and 116 Black older adults...

Circulation

Khera AV, Kathiresan S.
PMID: 28289003
Circulation. 2017 Mar 14;135(11):1005-1007. doi: 10.1161/CIRCULATIONAHA.116.026479.

No abstract available.

International journal of nephrology

Flythe JE, Li NC, Lin SF, Brunelli SM, Hymes J, Lacson E.
PMID: 25530881
Int J Nephrol. 2014;2014:961978. doi: 10.1155/2014/961978. Epub 2014 Nov 04.

Cardiopulmonary arrest during and proximate to hemodialysis is rare but highly fatal. Studies have examined peridialytic sudden cardiac event risk factors, but no study has considered associates of cardiopulmonary arrests (fatal and nonfatal events including cardiac and respiratory causes)....

BMJ global health

Subbaraman R, de Mondesert L, Musiimenta A, Pai M, Mayer KH, Thomas BE, Haberer J.
PMID: 30364330
BMJ Glob Health. 2018 Oct 11;3(5):e001018. doi: 10.1136/bmjgh-2018-001018. eCollection 2018.

Poor medication adherence may increase rates of loss to follow-up, disease relapse and drug resistance for individuals with active tuberculosis (TB). While TB programmes have historically used directly observed therapy (DOT) to address adherence, concerns have been raised about...

Healthcare (Amsterdam, Netherlands)

Butala NM, Hidrue MK, Swersey AJ, Singh JP, Weilburg JB, Ferris TG, Armstrong KA, Wasfy JH.
PMID: 30744992
Healthc (Amst). 2019 Dec;7(4). doi: 10.1016/j.hjdsi.2019.02.001. Epub 2019 Feb 08.

BACKGROUND: As physician groups consolidate and value-based payment replaces traditional fee-for-service systems, physician practices have greater need to accurately measure individual physician clinical productivity within team-based systems. We compared methodologies to measure individual physician outpatient clinical productivity after adjustment...

Annual review of cancer biology

Santana-Codina N, Mancias JD, Kimmelman AC.
PMID: 31119201
Annu Rev Cancer Biol. 2017 Mar;1:19-39. doi: 10.1146/annurev-cancerbio-041816-122338.

Autophagy is a highly conserved and regulated process that targets proteins and damaged organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and cell survival. The role of autophagy in cancer is dynamic and depends, in part, on...

Clinical and translational gastroenterology

Mima K, Cao Y, Chan AT, Qian ZR, Nowak JA, Masugi Y, Shi Y, Song M, da Silva A, Gu M, Li W, Hamada T, Kosumi K, Hanyuda A, Liu L, Kostic AD, Giannakis M, Bullman S, Brennan CA, Milner DA, Baba H, Garraway LA, Meyerhardt JA, Garrett WS, Huttenhower C, Meyerson M, Giovannucci EL, Fuchs CS, Nishihara R, Ogino S.
PMID: 27811909
Clin Transl Gastroenterol. 2016 Nov 03;7(11):e200. doi: 10.1038/ctg.2016.53.

OBJECTIVES: Evidence suggests a possible role of Fusobacterium nucleatum in colorectal carcinogenesis, especially in right-sided proximal colorectum. Considering a change in bowel contents and microbiome from proximal to distal colorectal segments, we hypothesized that the proportion of colorectal carcinoma...

NPJ precision oncology

Ogino S, Jhun I, Mata DA, Soong TR, Hamada T, Liu L, Nishihara R, Giannakis M, Cao Y, Manson JE, Nowak JA, Chan AT.
PMID: 29552640
NPJ Precis Oncol. 2017;1. doi: 10.1038/s41698-017-0042-x. Epub 2017 Dec 06.

Precision medicine has a goal of customizing disease prevention and treatment strategies. Under the precision medicine paradigm, each patient has unique pathologic processes resulting from cellular genomic, epigenomic, proteomic, and metabolomic alterations, which are influenced by pharmacological, environmental, microbial,...

Cell reports

Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, Nosho K, Nowak JA, Lawrence MS, Giovannucci EL, Chan AT, Ng K, Meyerhardt JA, Van Allen EM, Getz G, Gabriel SB, Lander ES, Wu CJ, Fuchs CS, Ogino S, Garraway LA.
PMID: 27149842
Cell Rep. 2016 Apr 26;15(4):857-865. doi: 10.1016/j.celrep.2016.03.075. Epub 2016 Apr 14.

Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 incident colorectal cancers (CRCs) and integrated the results with tumor immunity, pathology, and survival data. We identified...