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Showing 1 to 12 of 107 entries
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Corrigendum: Lanosterol reverses protein aggregation in cataracts.

Nature

Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Perry JJ, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K.
PMID: 26308894
Nature. 2015 Oct 22;526(7574):595. doi: 10.1038/nature15253. Epub 2015 Aug 26.

No abstract available.

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Zhao L, Chen XJ, Zhu J, et al. Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature. 2015;526(7574):595doi: 10.1038/nature15253.
Zhao, L., Chen, X. J., Zhu, J., Xi, Y. B., Yang, X., Hu, L. D., Ouyang, H., Patel, S. H., Jin, X., Lin, D., Wu, F., Flagg, K., Cai, H., Li, G., Cao, G., Lin, Y., Chen, D., Wen, C., Chung, C., Wang, Y., Qiu, A., Yeh, E., Wang, W., Hu, X., Grob, S., Abagyan, R., Su, Z., Tjondro, H. C., Zhao, X. J., Luo, H., Hou, R., Perry, J. J., Gao, W., Kozak, I., Granet, D., Li, Y., Sun, X., Wang, J., Zhang, L., Liu, Y., Yan, Y. B., & Zhang, K. (2015). Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature, 526(7574), 595. https://doi.org/10.1038/nature15253
Zhao, Ling, et al. "Corrigendum: Lanosterol reverses protein aggregation in cataracts." Nature vol. 526,7574 (2015): 595. doi: https://doi.org/10.1038/nature15253
Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Perry JJ, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature. 2015 Oct 22;526(7574):595. doi: 10.1038/nature15253. Epub 2015 Aug 26. PMID: 26308894.
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Morphology and chemistry of brown rat,Rattus norvegicus, preputial and clitoral glands.

Journal of chemical ecology

Natynczuk SE, Macdonald DW, Tattersall FH.
PMID: 24234023
J Chem Ecol. 1995 Feb;21(2):247-60. doi: 10.1007/BF02036655.

In contrast to previous results from laboratory rats, when sexual dimorphism occurred, clitoral glands from wild female rats were heavier and accounted for a greater proportion of body mass than preputial glands from wild males. Gland length and weight...

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Natynczuk SE, Macdonald DW, Tattersall FH. Morphology and chemistry of brown rat,Rattus norvegicus, preputial and clitoral glands. J Chem Ecol. 1995;21(2):247-60doi: 10.1007/BF02036655.
Natynczuk, S. E., Macdonald, D. W., & Tattersall, F. H. (1995). Morphology and chemistry of brown rat,Rattus norvegicus, preputial and clitoral glands. Journal of chemical ecology, 21(2), 247-60. https://doi.org/10.1007/BF02036655
Natynczuk, S E, et al. "Morphology and chemistry of brown rat,Rattus norvegicus, preputial and clitoral glands." Journal of chemical ecology vol. 21,2 (1995): 247-60. doi: https://doi.org/10.1007/BF02036655
Natynczuk SE, Macdonald DW, Tattersall FH. Morphology and chemistry of brown rat,Rattus norvegicus, preputial and clitoral glands. J Chem Ecol. 1995 Feb;21(2):247-60. doi: 10.1007/BF02036655. PMID: 24234023.
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Sterol conjugates of two phenotypically different calli of Beta vulgaris.

Plant cell reports

Ripa PV, Adler JH.
PMID: 24248657
Plant Cell Rep. 1987 Jun;6(3):219-22. doi: 10.1007/BF00268484.

Steryl glycosides are the predominant form of sterol at 88% of the total sterol in non-betalain producing calli of Beta vulgaris. The total sterol decreases and sterol form shifts from steryl glycosides to 97% free sterol upon the transition...

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Ripa PV, Adler JH. Sterol conjugates of two phenotypically different calli of Beta vulgaris. Plant Cell Rep. 1987;6(3):219-22doi: 10.1007/BF00268484.
Ripa, P. V., & Adler, J. H. (1987). Sterol conjugates of two phenotypically different calli of Beta vulgaris. Plant cell reports, 6(3), 219-22. https://doi.org/10.1007/BF00268484
Ripa, P V, and Adler, J H. "Sterol conjugates of two phenotypically different calli of Beta vulgaris." Plant cell reports vol. 6,3 (1987): 219-22. doi: https://doi.org/10.1007/BF00268484
Ripa PV, Adler JH. Sterol conjugates of two phenotypically different calli of Beta vulgaris. Plant Cell Rep. 1987 Jun;6(3):219-22. doi: 10.1007/BF00268484. PMID: 24248657.
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Sterol phylogenesis and algal evolution.

Proceedings of the National Academy of Sciences of the United States of America

Nes WD, Norton RA, Crumley FG, Madigan SJ, Katz ER.
PMID: 11607106
Proc Natl Acad Sci U S A. 1990 Oct;87(19):7565-9. doi: 10.1073/pnas.87.19.7565.

The stereochemistry of several sterol precursors and end products synthesized by two fungal-like micro-organisms Prototheca wickerhamii (I) and Dictyostelium discoideum (II) have been determined by chromatographic (TLC, GLC, and HPLC) and spectral (UV, MS, and 1H NMR) methods. From...

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Nes WD, Norton RA, Crumley FG, et al. Sterol phylogenesis and algal evolution. Proc Natl Acad Sci U S A. 1990;87(19):7565-9doi: 10.1073/pnas.87.19.7565.
Nes, W. D., Norton, R. A., Crumley, F. G., Madigan, S. J., & Katz, E. R. (1990). Sterol phylogenesis and algal evolution. Proceedings of the National Academy of Sciences of the United States of America, 87(19), 7565-9. https://doi.org/10.1073/pnas.87.19.7565
Nes, W D, et al. "Sterol phylogenesis and algal evolution." Proceedings of the National Academy of Sciences of the United States of America vol. 87,19 (1990): 7565-9. doi: https://doi.org/10.1073/pnas.87.19.7565
Nes WD, Norton RA, Crumley FG, Madigan SJ, Katz ER. Sterol phylogenesis and algal evolution. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7565-9. doi: 10.1073/pnas.87.19.7565. PMID: 11607106; PMCID: PMC54788.
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Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene.

Metal-based drugs

Guran C, Barboiu M, Diaconescu P, Iluc V, Bojin M, Scozzafava A, Supuran CT.
PMID: 18475860
Met Based Drugs. 1998;5(5):287-94. doi: 10.1155/MBD.1998.287.

Metal complexes of dichloro-tetramorpholino-cyclophosphazatriene containing divalent cations such as Ni(II), Co(II), and Mn(II) have been prepared and characterised by standard physico-chemical procedures (elemental chemical analysis, IR and UV-VIS spectra, conductimetric measurement). The newly synthesised compounds possessed antifungal activity against...

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Guran C, Barboiu M, Diaconescu P, et al. Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene. Met Based Drugs. 1998;5(5):287-94doi: 10.1155/MBD.1998.287.
Guran, C., Barboiu, M., Diaconescu, P., Iluc, V., Bojin, M., Scozzafava, A., & Supuran, C. T. (1998). Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene. Metal-based drugs, 5(5), 287-94. https://doi.org/10.1155/MBD.1998.287
Guran, C, et al. "Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene." Metal-based drugs vol. 5,5 (1998): 287-94. doi: https://doi.org/10.1155/MBD.1998.287
Guran C, Barboiu M, Diaconescu P, Iluc V, Bojin M, Scozzafava A, Supuran CT. Synthesis and antifungal activity of metal complexes containing dichloro-tetramorpholino-cyclophosphazatriene. Met Based Drugs. 1998;5(5):287-94. doi: 10.1155/MBD.1998.287. PMID: 18475860; PMCID: PMC2365132.
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Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors.

Metal-based drugs

Barboiu M, Supuran CT, Scozzafava A, Guran C, Diaconescu P, Bojin M, Iluc V, Cot L.
PMID: 18475888
Met Based Drugs. 1999;6(2):101-10. doi: 10.1155/MBD.1999.101.

Poly- and mononuclear metal complexes of 2,3,11,12-bis[4-(10-aminodecylcarbonyl)]benzo-18- crown-6 (L) and Cu(II); Ni(II); Co(II) and Cr(III) have been synthesized and characterized by standard physico-chemical procedures. In the newly prepared complexes the crown moiety oxygen atoms of the macrocyclic host did...

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Barboiu M, Supuran CT, Scozzafava A, et al. Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors. Met Based Drugs. 1999;6(2):101-10doi: 10.1155/MBD.1999.101.
Barboiu, M., Supuran, C. T., Scozzafava, A., Guran, C., Diaconescu, P., Bojin, M., Iluc, V., & Cot, L. (1999). Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors. Metal-based drugs, 6(2), 101-10. https://doi.org/10.1155/MBD.1999.101
Barboiu, M, et al. "Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors." Metal-based drugs vol. 6,2 (1999): 101-10. doi: https://doi.org/10.1155/MBD.1999.101
Barboiu M, Supuran CT, Scozzafava A, Guran C, Diaconescu P, Bojin M, Iluc V, Cot L. Functionalized Derivatives of Benzo-Crown Ethers. Part 4. Antifungal Macrocyclic Supramolecular Complexes of Transition Metal Ions Acting as Lanosterol-14-alpha-Demethylase Ihibitors. Met Based Drugs. 1999;6(2):101-10. doi: 10.1155/MBD.1999.101. PMID: 18475888; PMCID: PMC2365158.
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[Triterpenes and steroids in seeds of Solanum dulcamara].

Planta medica

Willuhn G, May S, Merfort I.
PMID: 17396951
Planta Med. 1982 Oct;46(2):99-104. doi: 10.1055/s-2007-970029.

In seeds of Solanum dulcamara L. the 4,4-dimethylsterols cycloartenol, lanosterol, cycloartanol, 24-dihydrolanosterol, 24-methylenecycloartanol, and 24-methylenelanost-8-en-3beta-ol, the 4alpha-methylsterols 31-norcycloartenol, 31-norlanosterol, 31-norlanost-8-en-3beta-ol, lophenol, cycloeucalenol, obtusifoliol, gramisterol, and citrostadienol and the sterols cholesterol, 24-methylenecholesterol, campesterol, isofucosterol, sitosterol, and stigmasterol were identified by...

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Willuhn G, May S, Merfort I. Triterpene und Steroide im Samen von Solanum dulcamara. [Triterpenes and steroids in seeds of Solanum dulcamara]. Planta Med. 1982;46(2):99-104doi: 10.1055/s-2007-970029.
Willuhn, G., May, S., & Merfort, I. (1982). Triterpene und Steroide im Samen von Solanum dulcamara. [Triterpenes and steroids in seeds of Solanum dulcamara]. Planta medica, 46(2), 99-104. https://doi.org/10.1055/s-2007-970029
Willuhn, G, et al. "Triterpene und Steroide im Samen von Solanum dulcamara." [Triterpenes and steroids in seeds of Solanum dulcamara]. Planta medica vol. 46,2 (1982): 99-104. doi: https://doi.org/10.1055/s-2007-970029
Willuhn G, May S, Merfort I. Triterpene und Steroide im Samen von Solanum dulcamara. [Triterpenes and steroids in seeds of Solanum dulcamara]. Planta Med. 1982 Oct;46(2):99-104. doi: 10.1055/s-2007-970029. German. PMID: 17396951.
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Seasonal variation of lipids in femoral gland secretions of male green iguanas (Iguana iguana).

Journal of chemical ecology

Alberts AC, Sharp TR, Werner DI, Weldon PJ.
PMID: 24253964
J Chem Ecol. 1992 May;18(5):703-12. doi: 10.1007/BF00994608.

Femoral gland secretions were collected from 21 captive adult male green iguanas (Iguana iguana) in Orotina, Costa Rica, and San Diego, California, during the breeding (November) and nonbreeding (March) seasons. Lipids were extracted with methylene chloride, weighed, separated by...

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Alberts AC, Sharp TR, Werner DI, et al. Seasonal variation of lipids in femoral gland secretions of male green iguanas (Iguana iguana). J Chem Ecol. 1992;18(5):703-12doi: 10.1007/BF00994608.
Alberts, A. C., Sharp, T. R., Werner, D. I., & Weldon, P. J. (1992). Seasonal variation of lipids in femoral gland secretions of male green iguanas (Iguana iguana). Journal of chemical ecology, 18(5), 703-12. https://doi.org/10.1007/BF00994608
Alberts, A C, et al. "Seasonal variation of lipids in femoral gland secretions of male green iguanas (Iguana iguana)." Journal of chemical ecology vol. 18,5 (1992): 703-12. doi: https://doi.org/10.1007/BF00994608
Alberts AC, Sharp TR, Werner DI, Weldon PJ. Seasonal variation of lipids in femoral gland secretions of male green iguanas (Iguana iguana). J Chem Ecol. 1992 May;18(5):703-12. doi: 10.1007/BF00994608. PMID: 24253964.
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Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface.

Journal of the American Chemical Society

Kang H, Yang Z, Zhou R.
PMID: 29916249
J Am Chem Soc. 2018 Jul 11;140(27):8479-8486. doi: 10.1021/jacs.8b03065. Epub 2018 Jul 02.

Cataracts are a leading cause of vision impairment, which stem from the misfolding and aggregation of crystallins in the eye lens. Despite its prevalence and severity, the detailed mechanism by which misfolded crystallins aggregate into cataracts remains elusive. Recently,...

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Kang H, Yang Z, Zhou R. Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface. J Am Chem Soc. 2018;140(27):8479-8486doi: 10.1021/jacs.8b03065.
Kang, H., Yang, Z., & Zhou, R. (2018). Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface. Journal of the American Chemical Society, 140(27), 8479-8486. https://doi.org/10.1021/jacs.8b03065
Kang, Hongsuk, et al. "Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface." Journal of the American Chemical Society vol. 140,27 (2018): 8479-8486. doi: https://doi.org/10.1021/jacs.8b03065
Kang H, Yang Z, Zhou R. Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface. J Am Chem Soc. 2018 Jul 11;140(27):8479-8486. doi: 10.1021/jacs.8b03065. Epub 2018 Jul 02. PMID: 29916249.
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Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach.

Heliyon

Khan MS, Agrawal R, Ubaidullah M, Hassan MI, Tarannum N.
PMID: 31692746
Heliyon. 2019 Oct 18;5(10):e02615. doi: 10.1016/j.heliyon.2019.e02615. eCollection 2019 Oct.

An ecofriendly itinerary for the synthesis of newly substituted chromene-3-carboxamide derivatives was undertaken to avoid impurities, usage of toxic solvents, toxic catalyst, and having improved quantitative yields. The green synthesis involves the condensation of substituted salicylaldehyde with N-(substituted)phenyl malonic...

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Khan MS, Agrawal R, Ubaidullah M, et al. Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach. Heliyon. 2019;5(10):e02615doi: 10.1016/j.heliyon.2019.e02615.
Khan, M. S., Agrawal, R., Ubaidullah, M., Hassan, M. I., & Tarannum, N. (2019). Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach. Heliyon, 5(10), e02615. https://doi.org/10.1016/j.heliyon.2019.e02615
Khan, Mohd Shahnawaz, et al. "Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach." Heliyon vol. 5,10 (2019): e02615. doi: https://doi.org/10.1016/j.heliyon.2019.e02615
Khan MS, Agrawal R, Ubaidullah M, Hassan MI, Tarannum N. Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach. Heliyon. 2019 Oct 18;5(10):e02615. doi: 10.1016/j.heliyon.2019.e02615. eCollection 2019 Oct. PMID: 31692746; PMCID: PMC6806407.
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Antifungal activity of amino-alcohols based cationic surfactants and in silico, homology modeling, docking and molecular dynamics studies against lanosterol 14-α-demethylase enzyme.

Journal of biomolecular structure & dynamics

Hafidi Z, El Achouri M, O Sousa FF, Pérez L.
PMID: 33754947
J Biomol Struct Dyn. 2021 Mar 23;1-17. doi: 10.1080/07391102.2021.1902396. Epub 2021 Mar 23.

Fungi are being responsible for causing serious infections in humans and animals. The opportunistic microorganisms provoke environmental contaminations in health and storage facilities to represent a serious concern to health security. The present work investigates the antifungal activity of...

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Hafidi Z, El Achouri M, O Sousa FF, et al. Antifungal activity of amino-alcohols based cationic surfactants and in silico, homology modeling, docking and molecular dynamics studies against lanosterol 14-α-demethylase enzyme. J Biomol Struct Dyn. 2021;1-17doi: 10.1080/07391102.2021.1902396.
Hafidi, Z., El Achouri, M., O Sousa, F. F., & Pérez, L. (2021). Antifungal activity of amino-alcohols based cationic surfactants and in silico, homology modeling, docking and molecular dynamics studies against lanosterol 14-α-demethylase enzyme. Journal of biomolecular structure & dynamics, 1-17. https://doi.org/10.1080/07391102.2021.1902396
Hafidi, Zakaria, et al. "Antifungal activity of amino-alcohols based cationic surfactants and in silico, homology modeling, docking and molecular dynamics studies against lanosterol 14-α-demethylase enzyme." Journal of biomolecular structure & dynamics vol. (2021): 1-17. doi: https://doi.org/10.1080/07391102.2021.1902396
Hafidi Z, El Achouri M, O Sousa FF, Pérez L. Antifungal activity of amino-alcohols based cationic surfactants and in silico, homology modeling, docking and molecular dynamics studies against lanosterol 14-α-demethylase enzyme. J Biomol Struct Dyn. 2021 Mar 23;1-17. doi: 10.1080/07391102.2021.1902396. Epub 2021 Mar 23. PMID: 33754947.
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Alopecia-mental retardation syndrome: Molecular genetics of a rare neuro-dermal disorder.

Annals of human genetics

Muzammal M, Ahmad S, Ali MZ, Khan MA.
PMID: 33881165
Ann Hum Genet. 2021 Sep;85(5):147-154. doi: 10.1111/ahg.12425. Epub 2021 Apr 21.

Alopecia-mental retardation syndrome (APMR) is a rare autosomal recessive neuro-dermal disorder. It is characterized by heterogeneous phenotypic features, that is, absence of hair on the scalp, eyelashes, and eyebrows and mild to severe intellectual disability. So far, approximately 14...

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Muzammal M, Ahmad S, Ali MZ, et al. Alopecia-mental retardation syndrome: Molecular genetics of a rare neuro-dermal disorder. Ann Hum Genet. 2021;85(5):147-154doi: 10.1111/ahg.12425.
Muzammal, M., Ahmad, S., Ali, M. Z., & Khan, M. A. (2021). Alopecia-mental retardation syndrome: Molecular genetics of a rare neuro-dermal disorder. Annals of human genetics, 85(5), 147-154. https://doi.org/10.1111/ahg.12425
Muzammal, Muhammad, et al. "Alopecia-mental retardation syndrome: Molecular genetics of a rare neuro-dermal disorder." Annals of human genetics vol. 85,5 (2021): 147-154. doi: https://doi.org/10.1111/ahg.12425
Muzammal M, Ahmad S, Ali MZ, Khan MA. Alopecia-mental retardation syndrome: Molecular genetics of a rare neuro-dermal disorder. Ann Hum Genet. 2021 Sep;85(5):147-154. doi: 10.1111/ahg.12425. Epub 2021 Apr 21. PMID: 33881165.
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