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Study of urinary leukotriene E4 levels in children with acute asthma.

International journal of general medicine

Abd El-Motaleb GS, Abou Amer AA, Elawa GM, Abo Alsood Abd Elfattah M.
PMID: 24623986
Int J Gen Med. 2014 Mar 03;7:131-5. doi: 10.2147/IJGM.S56660. eCollection 2014.

OBJECTIVE: The goal of this study was to evaluate the impact of urinary leukotriene E4 (ULTE4) in asthmatic children during acute asthma exacerbation. Also, we wanted to correlate it with the total serum (TS) immunoglobulin (Ig) E level in...

Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.

Environmental health : a global access science source

Drieling RL, Sampson PD, Krenz JE, Tchong French MI, Jansen KL, Massey AE, Farquhar SA, Min E, Perez A, Riederer AM, Torres E, Younglove LR, Aisenberg E, Andra SS, Kim-Schulze S, Karr CJ.
PMID: 34980119
Environ Health. 2022 Jan 03;21(1):1. doi: 10.1186/s12940-021-00816-w.

BACKGROUND: Data on pediatric asthma morbidity and effective environmental interventions in U.S. agricultural settings are few. We evaluated the effectiveness of HEPA air cleaners on asthma morbidity among a cohort of rural Latino children.METHODS: Seventy-five children with poorly controlled...

Metabonomic Variation of Exopolysaccharide from .

OncoTargets and therapy

Lu Y, Wang J, Ji Y, Chen K.
PMID: 31819498
Onco Targets Ther. 2019 Nov 20;12:10023-10033. doi: 10.2147/OTT.S226451. eCollection 2019.

BACKGROUND: Colorectal cancer (CRC), which occurs at the junction of the rectum and sigmoid colon, is a common malignancy associated with poor prognosis and high mortality worldwide. The exopolysaccharide (EPS1-1), isolated from the fermentation broth of METHODS: In the...

Ratio of leukotriene e(4) to exhaled nitric oxide and the therapeutic response in children with exercise-induced bronchoconstriction.

Allergy, asthma & immunology research

Baek HS, Cho J, Kim JH, Oh JW, Lee HB.
PMID: 23277875
Allergy Asthma Immunol Res. 2013 Jan;5(1):26-33. doi: 10.4168/aair.2013.5.1.26. Epub 2012 Oct 10.

PURPOSE: This study assessed the association between the ratio of leukotriene E(4) (LTE(4)) to fractional exhaled nitric oxide (FE(NO)) in the response of children with exercise-induced bronchoconstriction (EIB) enrolled in a therapeutic trial with montelukast or inhaled corticosteroid (fluticasone...

Regression calibration with instrumental variables for longitudinal models with interaction terms, and application to air pollution studies.

Environmetrics

Strand M, Sillau S, Grunwald GK, Rabinovitch N.
PMID: 26640396
Environmetrics. 2015 Sep;26(6):393-405. doi: 10.1002/env.2354. Epub 2015 Aug 10.

In this paper, we derive forms of estimators and associated variances for regression calibration with instrumental variables in longitudinal models that include interaction terms between two unobservable predictors and interactions between these predictors and covariates not measured with error;...

Negative ion tandem mass spectrometry of leukotriene E4, and LTE 4, metabolites: Identification of LTE 4, in human urine.

Journal of the American Society for Mass Spectrometry

Sala A, Kayganich K, Zirrolli JA, Murphy RC.
PMID: 24242351
J Am Soc Mass Spectrom. 1991 Aug;2(4):314-21. doi: 10.1016/1044-0305(91)80023-Z.

The sulfidopeptide leukotrienes, leukotriene E4, (LTE4,) and its N-acetyl derivative and several ω- and β-oxidized metabolites of LTE4, have been analyzed by tandem mass spectrometry. [M-H](-) ions were produced by continuous flow fast atom bombardment, and collision-induced dissociation of...

Urine Leukotriene E4: Implications as a Biomarker in Chronic Rhinosinusitis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Choby G, Low CM, Levy JM, Stokken JK, Pinheiro-Neto C, Bartemes K, Marino M, Han JK, Divekar R, O'Brien EK, Lal D.
PMID: 33973823
Otolaryngol Head Neck Surg. 2021 May 11;1945998211011060. doi: 10.1177/01945998211011060. Epub 2021 May 11.

OBJECTIVE: To provide a comprehensive state-of-the-art review of the emerging role of urine leukotriene E4 (uLTE4) as a biomarker in the diagnosis of chronic rhinosinusitis (CRS), aspirin-exacerbated respiratory disease (AERD), and asthma.DATA SOURCES: Ovid MEDLINE(R), Ovid EMBASE, Ovid Cochrane...

Divergent PGD.

Prostaglandins & other lipid mediators

Butterfield JH, Singh RJ.
PMID: 34029712
Prostaglandins Other Lipid Mediat. 2021 Aug;155:106563. doi: 10.1016/j.prostaglandins.2021.106563. Epub 2021 May 21.

Aspirin-exacerbated respiratory disease and some cases of chronic idiopathic urticaria are disorders in which increased baseline urinary excretion of leukotriene(LT)E4 further increases following aspirin administration. Increased urinary excretion of the metabolites of prostaglandin D2, 11β-prostaglandin(PG)F2α and (2,3-dinor)-11β-PGF2α, have been...

Clinical Characteristics, Urinary Leukotriene E4 Levels, and Aspirin Desensitization Results in Patients With NSAID-Induced Blended Reactions.

Allergy, asthma & immunology research

Klaewsongkram J, Buranapraditkun S, Mongkolpathumrat P, Palapinyo S, Chantaphakul H.
PMID: 33474858
Allergy Asthma Immunol Res. 2021 Mar;13(2):229-244. doi: 10.4168/aair.2021.13.2.229.

PURPOSE: Data on non-steroidal anti-inflammatory drug (NSAID) hypersensitivity in Southeast Asia are scarce. Increased urinary leukotriene E4 (uLTE4) levels have been suggested as a biomarker of NSAID-exacerbated respiratory disease (NERD). This study investigated clinical patterns of NSAID sensitivity in...

Urinary leukotriene E4 is a biomarker for chronic rhinosinusitis associated with leukotriene dysregulation irrespective of aspirin sensitivity status.

International forum of allergy & rhinology

Idler BM, Lal D, Marino MJ.
PMID: 34821062
Int Forum Allergy Rhinol. 2021 Nov 24; doi: 10.1002/alr.22915. Epub 2021 Nov 24.

No abstract available.

Anaphylaxis caused by tipepidine hibenzate, a central antitussive drug.

Respirology case reports

Mochizuki E, Shirai T, Noguchi R, Mitsui C, Taniguchi M, Suda T.
PMID: 25802739
Respirol Case Rep. 2015 Mar;3(1):3-5. doi: 10.1002/rcr2.85. Epub 2014 Dec 02.

Tipepidine hibenzate, a central antitussive drug, is widely used in the management of cough and is generally safe and well tolerated. We present here a case of anaphylaxis caused by this drug. When the patient had caught a cold...

Effect of TGF-β1 on eosinophils to induce cysteinyl leukotriene E4 production in aspirin-exacerbated respiratory disease.

PloS one

Choi Y, Sim S, Lee DH, Lee HR, Ban GY, Shin YS, Kim YK, Park HS.
PMID: 34437574
PLoS One. 2021 Aug 26;16(8):e0256237. doi: 10.1371/journal.pone.0256237. eCollection 2021.

Cysteinyl leukotriene (cysLT) overproduction and eosinophil activation are hallmarks of aspirin-exacerbated respiratory disease (AERD). However, pathogenic mechanisms of AERD remain to be clarified. Here, we aimed to find the significance of transforming growth factor beta 1 (TGF-β1) in association...

Showing 1 to 12 of 23 entries