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Optimizing mouse models of neurodegenerative disorders: are therapeutics in sight?.

Future neurology

Lutz CM, Osborne MA.
PMID: 29479291
Future Neurol. 2013;9(1):67-75. doi: 10.2217/fnl.13.66. Epub 2013 Dec 16.

The genomic and biologic conservation between mice and humans, along with our increasing ability to manipulate the mouse genome, places the mouse as a premier model for deciphering disease mechanisms and testing potential new therapies. Despite these advantages, mouse...

Diabetes research in children network:availability of protocol data sets.

Journal of diabetes science and technology

Ruedy KJ, Beck RW, Xing D, Kollman C.
PMID: 18490965
J Diabetes Sci Technol. 2007 Sep;1(5):738-45. doi: 10.1177/193229680700100519.

The Diabetes Research in Children Network (DirecNet) was established in 2001 by the National Institute of Child Health and Human Development and the National Institute of Diabetes and Digestive and Kidney Diseases through special congressional funding for type 1...

Antiretroviral Drug Levels and Interactions Affect Lipid, Lipoprotein, and Glucose Metabolism in HIV-1 Seronegative Subjects: A Pharmacokinetic-Pharmacodynamic Analysis.

Metabolic syndrome and related disorders

Rosenkranz SL, Yarasheski KE, Para MF, Reichman RC, Morse GD.
PMID: 18007962
Metab Syndr Relat Disord. 2007 Jun;5(2):163-73. doi: 10.1089/met.2006.0034.

BACKGROUND: HIV-infected patients treated with antiretroviral medications (ARVs) develop undesirable changes in lipid and glucose metabolism that mimic the metabolic syndrome and may be proatherogenic. Antiretroviral drug levels and their interactions may contribute to these metabolic alterations.METHODS: Fifty six...

Showing 1 to 3 of 3 entries