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c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases.

The open rheumatology journal

Guma M, Firestein GS.
PMID: 23028407
Open Rheumatol J. 2012;6:220-31. doi: 10.2174/1874312901206010220. Epub 2012 Sep 07.

The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are activated by environmental stress. JNK is also activated by proinflammatory cytokines, such as TNF and IL-1, and Toll-like receptor ligands. This pathway, therefore,...

Showing 1 to 1 of 1 entries