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Mitochondrial contribution to Parkinson's disease pathogenesis.

Parkinson's disease

Schapira AH, Gegg M.
PMID: 21687805
Parkinsons Dis. 2011;2011:159160. doi: 10.4061/2011/159160. Epub 2011 Apr 28.

The identification of the etiologies and pathogenesis of Parkinson's disease (PD) should play an important role in enabling the development of novel treatment strategies to prevent or slow the progression of the disease. The last few years have seen...

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Schapira AH, Gegg M. Mitochondrial contribution to Parkinson's disease pathogenesis. Parkinsons Dis. 2011;2011:159160doi: 10.4061/2011/159160.
Schapira, A. H., & Gegg, M. (2011). Mitochondrial contribution to Parkinson's disease pathogenesis. Parkinson's disease, 2011159160. https://doi.org/10.4061/2011/159160
Schapira, Anthony H V, and Gegg, Matthew. "Mitochondrial contribution to Parkinson's disease pathogenesis." Parkinson's disease vol. 2011 (2011): 159160. doi: https://doi.org/10.4061/2011/159160
Schapira AH, Gegg M. Mitochondrial contribution to Parkinson's disease pathogenesis. Parkinsons Dis. 2011;2011:159160. doi: 10.4061/2011/159160. Epub 2011 Apr 28. PMID: 21687805; PMCID: PMC3109314.
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A tangled web - tau and sporadic Parkinson's disease.

Frontiers in psychiatry

Wray S, Lewis PA.
PMID: 21423457
Front Psychiatry. 2010 Dec 27;1:150. doi: 10.3389/fpsyt.2010.00150. eCollection 2010.

Parkinson's disease (PD) represents a major challenge for health care systems around the world: it is the most common degenerative movement disorder of old age, affecting over 100,000 people in the UK alone (Schrag et al., 2000). Despite the...

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Wray S, Lewis PA. A tangled web - tau and sporadic Parkinson's disease. Front Psychiatry. 2010;1:150doi: 10.3389/fpsyt.2010.00150.
Wray, S., & Lewis, P. A. (2010). A tangled web - tau and sporadic Parkinson's disease. Frontiers in psychiatry, 1150. https://doi.org/10.3389/fpsyt.2010.00150
Wray, Selina, and Lewis, Patrick A. "A tangled web - tau and sporadic Parkinson's disease." Frontiers in psychiatry vol. 1 (2010): 150. doi: https://doi.org/10.3389/fpsyt.2010.00150
Wray S, Lewis PA. A tangled web - tau and sporadic Parkinson's disease. Front Psychiatry. 2010 Dec 27;1:150. doi: 10.3389/fpsyt.2010.00150. eCollection 2010. PMID: 21423457; PMCID: PMC3059613.
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LRRK2: a problem lurking in vesicle trafficking?.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Dihanich S, Manzoni C.
PMID: 21734269
J Neurosci. 2011 Jul 06;31(27):9787-8. doi: 10.1523/JNEUROSCI.1976-11.2011.

No abstract available.

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Dihanich S, Manzoni C. LRRK2: a problem lurking in vesicle trafficking?. J Neurosci. 2011;31(27):9787-8doi: 10.1523/JNEUROSCI.1976-11.2011.
Dihanich, S., & Manzoni, C. (2011). LRRK2: a problem lurking in vesicle trafficking?. The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(27), 9787-8. https://doi.org/10.1523/JNEUROSCI.1976-11.2011
Dihanich, Sybille, and Manzoni, Claudia. "LRRK2: a problem lurking in vesicle trafficking?." The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 31,27 (2011): 9787-8. doi: https://doi.org/10.1523/JNEUROSCI.1976-11.2011
Dihanich S, Manzoni C. LRRK2: a problem lurking in vesicle trafficking?. J Neurosci. 2011 Jul 06;31(27):9787-8. doi: 10.1523/JNEUROSCI.1976-11.2011. PMID: 21734269; PMCID: PMC3145097.
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Treatment of focal dystonia.

Current treatment options in neurology

Batla A, Stamelou M, Bhatia KP.
PMID: 22415705
Curr Treat Options Neurol. 2012 Jun;14(3):213-29. doi: 10.1007/s11940-012-0169-6.

OPINION STATEMENT: Dystonia is characterized by repetitive twisting movements or abnormal postures due to involuntary muscle activity. When limited to a single body region it is called focal dystonia. Examples of focal dystonia include cervical dystonia (neck), blepharospasm (eyes),...

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Batla A, Stamelou M, Bhatia KP. Treatment of focal dystonia. Curr Treat Options Neurol. 2012;14(3):213-29doi: 10.1007/s11940-012-0169-6.
Batla, A., Stamelou, M., & Bhatia, K. P. (2012). Treatment of focal dystonia. Current treatment options in neurology, 14(3), 213-29. https://doi.org/10.1007/s11940-012-0169-6
Batla, Amit, et al. "Treatment of focal dystonia." Current treatment options in neurology vol. 14,3 (2012): 213-29. doi: https://doi.org/10.1007/s11940-012-0169-6
Batla A, Stamelou M, Bhatia KP. Treatment of focal dystonia. Curr Treat Options Neurol. 2012 Jun;14(3):213-29. doi: 10.1007/s11940-012-0169-6. PMID: 22415705.
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Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA).

Current neuropharmacology

Schneider SA, Dusek P, Hardy J, Westenberger A, Jankovic J, Bhatia KP.
PMID: 23814539
Curr Neuropharmacol. 2013 Jan;11(1):59-79. doi: 10.2174/157015913804999469.

Our understanding of the syndromes of Neurodegeneration with Brain Iron Accumulation (NBIA) continues to grow considerably. In addition to the core syndromes of pantothenate kinase-associated neurodegeneration (PKAN, NBIA1) and PLA2G6-associated neurodegeneration (PLAN, NBIA2), several other genetic causes have been...

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Schneider SA, Dusek P, Hardy J, et al. Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA). Curr Neuropharmacol. 2013;11(1):59-79doi: 10.2174/157015913804999469.
Schneider, S. A., Dusek, P., Hardy, J., Westenberger, A., Jankovic, J., & Bhatia, K. P. (2013). Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA). Current neuropharmacology, 11(1), 59-79. https://doi.org/10.2174/157015913804999469
Schneider, Susanne A, et al. "Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA)." Current neuropharmacology vol. 11,1 (2013): 59-79. doi: https://doi.org/10.2174/157015913804999469
Schneider SA, Dusek P, Hardy J, Westenberger A, Jankovic J, Bhatia KP. Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA). Curr Neuropharmacol. 2013 Jan;11(1):59-79. doi: 10.2174/157015913804999469. PMID: 23814539; PMCID: PMC3580793.
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Brain Penetrant LRRK2 Inhibitor.

ACS medicinal chemistry letters

Choi HG, Zhang J, Deng X, Hatcher JM, Patricelli MP, Zhao Z, Alessi DR, Gray NS.
PMID: 23066449
ACS Med Chem Lett. 2012 Aug 09;3(8):658-662. doi: 10.1021/ml300123a. Epub 2012 Jun 18.

Activating mutations in leucine-rich repeat kinase 2 (LRRK2) are present in a subset of Parkinson's disease (PD) patients and may represent an attractive therapeutic target. Here we report a 2-anilino-4-methylamino-5-chloropyrimidine, HG-10-102-01(4) is a potent and selective inhibitor of wild-type...

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Choi HG, Zhang J, Deng X, et al. Brain Penetrant LRRK2 Inhibitor. ACS Med Chem Lett. 2012;3(8):658-662doi: 10.1021/ml300123a.
Choi, H. G., Zhang, J., Deng, X., Hatcher, J. M., Patricelli, M. P., Zhao, Z., Alessi, D. R., & Gray, N. S. (2012). Brain Penetrant LRRK2 Inhibitor. ACS medicinal chemistry letters, 3(8), 658-662. https://doi.org/10.1021/ml300123a
Choi, Hwan Geun, et al. "Brain Penetrant LRRK2 Inhibitor." ACS medicinal chemistry letters vol. 3,8 (2012): 658-662. doi: https://doi.org/10.1021/ml300123a
Choi HG, Zhang J, Deng X, Hatcher JM, Patricelli MP, Zhao Z, Alessi DR, Gray NS. Brain Penetrant LRRK2 Inhibitor. ACS Med Chem Lett. 2012 Aug 09;3(8):658-662. doi: 10.1021/ml300123a. Epub 2012 Jun 18. PMID: 23066449; PMCID: PMC3467149.
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Showing 1 to 6 of 6 entries