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Showing 1 to 11 of 11 entries
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Change point models for cognitive tests using semi-parametric maximum likelihood.

Computational statistics & data analysis

van den Hout A, Muniz-Terrera G, Matthews FE.
PMID: 23471297
Comput Stat Data Anal. 2013 Jan;57(1):684-698. doi: 10.1016/j.csda.2012.07.024.

Random-effects change point models are formulated for longitudinal data obtained from cognitive tests. The conditional distribution of the response variable in a change point model is often assumed to be normal even if the response variable is discrete and...

Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis.

Molecular autism

Sun X, Allison C, Matthews FE, Sharp SJ, Auyeung B, Baron-Cohen S, Brayne C.
PMID: 23570419
Mol Autism. 2013 Apr 09;4(1):7. doi: 10.1186/2040-2392-4-7.

BACKGROUND: The prevalence of autism spectrum conditions (ASC) is 1% in developed countries, but little data are available from mainland China, Hong Kong and Taiwan. This study synthesizes evidence relating to the prevalence of ASC in these areas and...

Investigating populations via penguins and their poo!.

Teaching statistics

Bonnett LJ, White SR.
PMID: 31588155
Teach Stat. 2019;41(3):101-105. doi: 10.1111/test.12195. Epub 2019 Feb 27.

We describe an activity that introduces students to population modelling, enables them to use estimates obtained from a sample to infer back to the population, and understands how the findings are translatable via penguins and their poo!

May the odds be ever in your favour.

Teaching statistics

Bonnett LJ, White SR.
PMID: 31427834
Teach Stat. 2018;40(3):94-97. doi: 10.1111/test.12162. Epub 2018 May 09.

Probability and chance are essential concepts, not just in statistics but in real life. We present an adaptable activity which investigates what we mean by bias, how we can identify bias, and how we can use it to our...

Estimating stroke-free and total life expectancy in the presence of non-ignorable missing values.

Journal of the Royal Statistical Society. Series A, (Statistics in Society)

van den Hout A, Matthews FE.
PMID: 20454440
J R Stat Soc Ser A Stat Soc. 2010 Apr;173(2):331-349. doi: 10.1111/j.1467-985X.2009.00610.x.

A continuous time three-state model with time-dependent transition intensities is formulated to describe transitions between healthy and unhealthy states before death. By using time continuously, known death times can be taken into account. To deal with possible non-ignorable missing...

Biased sampling activity: an investigation to promote discussion.

Teaching statistics

White SR, Bonnett LJ.
PMID: 30906081
Teach Stat. 2019;41(1):8-13. doi: 10.1111/test.12165. Epub 2018 Jun 20.

The statistical concept of sampling is often given little direct attention, typically reduced to the mantra "take a random sample". This low resource and adaptable activity demonstrates sampling and explores issues that arise due to biased sampling.

Beyond mild cognitive impairment: vascular cognitive impairment, no dementia (VCIND).

Alzheimer's research & therapy

Stephan BC, Matthews FE, Khaw KT, Dufouil C, Brayne C.
PMID: 19674437
Alzheimers Res Ther. 2009 Jul 09;1(1):4. doi: 10.1186/alzrt4.

Identifying the causes of dementia is important in the search for effective preventative and treatment strategies. The concept of mild cognitive impairment (MCI), as prodromal dementia, has been useful but remains controversial since in population-based studies it appears to...

Evolution of dementia diagnosis over time (1988-2013): Evidence from French and English cohorts. Implication for secular trends analyses.

Alzheimer's & dementia (Amsterdam, Netherlands)

Grasset L, Matthews FE, Pérès K, Foubert-Samier A, Helmer C, Dartigues JF, Brayne C.
PMID: 30310851
Alzheimers Dement (Amst). 2018 Aug 09;10:490-497. doi: 10.1016/j.dadm.2018.07.005. eCollection 2018.

INTRODUCTION: The aims of this study are to examine the evolution of clinical dementia diagnosis over 3 decades and to investigate secular trends of dementia.METHODS: Four cohorts covering a period from 1988 to 2013 were used: the Personnes Agées...

Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study.

Alzheimer's research & therapy

Llewellyn DJ, Lang IA, Matthews FE, Plassman BL, Rogers MA, Morgenstern LB, Fisher GG, Kabeto MU, Langa KM.
PMID: 20576093
Alzheimers Res Ther. 2010 Jun 24;2(3):19. doi: 10.1186/alzrt43.

INTRODUCTION: Evidence from clinical samples and geographically limited population studies suggests that vascular health, diabetes and apolipoprotein epsilon4 (APOE) are associated with dementia.METHODS: A population-based sample of 856 individuals aged 71 years or older from all contiguous regions of...

Joint Modeling of Longitudinal Change and Survival: An Investigation of the Association Between Change in Memory Scores and Death.

GeroPsych

Terrera GM, Piccinin AM, Johansson B, Matthews F, Hofer SM.
PMID: 23626569
GeroPsych (Bern). 2011 Dec 01;24(4):177-185. doi: 10.1024/1662-9647/a000047.

Joint longitudinal-survival models are useful when repeated measures and event time data are available and possibly associated. The application of this joint model in aging research is relatively rare, albeit particularly useful, when there is the potential for nonrandom...

Assessing dynamic functional connectivity in heterogeneous samples.

NeuroImage

Lehmann BCL, White SR, Henson RN, Cam-Can, Geerligs L.
PMID: 28578129
Neuroimage. 2017 Aug 15;157:635-647. doi: 10.1016/j.neuroimage.2017.05.065. Epub 2017 Jun 01.

Several methods have been developed to measure dynamic functional connectivity (dFC) in fMRI data. These methods are often based on a sliding-window analysis, which aims to capture how the brain's functional organization varies over the course of a scan....

Showing 1 to 11 of 11 entries