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Showing 1 to 12 of 14 entries
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Residential exposure to radon and DNA methylation across the lifecourse: an exploratory study in the ALSPAC birth cohort.

Wellcome open research

de Vocht F, Suderman M, Ruano-Ravina A, Thomas R, Wakeford R, Relton C, Tilling K, Boyd A.
PMID: 30906879
Wellcome Open Res. 2019 Apr 15;4:3. doi: 10.12688/wellcomeopenres.14991.2. eCollection 2019.

No abstract available.

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.

Molecular psychiatry

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA.
PMID: 26283641
Mol Psychiatry. 2016 Apr;21(4):585. doi: 10.1038/mp.2015.118. Epub 2015 Aug 18.

No abstract available.

Epigenome-wide association study of asthma and wheeze characterizes loci within .

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

Everson TM, Zhang H, Lockett GA, Kaushal A, Forthofer M, Ewart SL, Burrows K, Relton CL, Sharp GC, Henderson AJ, Patil VK, Rezwan FI, Arshad SH, Holloway JW, Karmaus W.
PMID: 31367216
Allergy Asthma Clin Immunol. 2019 Jul 24;15:43. doi: 10.1186/s13223-019-0356-z. eCollection 2019.

BACKGROUND: To identify novel epigenetic markers of adolescent asthma and replicate findings in an independent cohort, then explore whether such markers are detectable at birth, predictive of early-life wheeze, and associated with gene expression in cord blood.METHODS: We performed...

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation.

Molecular psychiatry

Sammallahti S, Cortes Hidalgo AP, Tuominen S, Malmberg A, Mulder RH, Brunst KJ, Alemany S, McBride NS, Yousefi P, Heiss JA, McRae N, Page CM, Jin J, Pesce G, Caramaschi D, Rifas-Shiman SL, Koen N, Adams CD, Magnus MC, Baïz N, Ratanatharathorn A, Czamara D, Håberg SE, Colicino E, Baccarelli AA, Cardenas A, DeMeo DL, Lawlor DA, Relton CL, Felix JF, van IJzendoorn MH, Bakermans-Kranenburg MJ, Kajantie E, Räikkönen K, Sunyer J, Sharp GC, Houtepen LC, Nohr EA, Sørensen TIA, Téllez-Rojo MM, Wright RO, Annesi-Maesano I, Wright J, Hivert MF, Wright RJ, Zar HJ, Stein DJ, London SJ, Cecil CAM, Tiemeier H, Lahti J.
PMID: 33414500
Mol Psychiatry. 2021 Jun;26(6):1832-1845. doi: 10.1038/s41380-020-00976-0. Epub 2021 Jan 07.

Maternal anxiety during pregnancy is associated with adverse foetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered foetal DNA methylation (DNAm) has been proposed as a potential underlying mechanism. In the current study, we performed a meta-analysis...

Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium.

Epigenetics

Ronkainen J, Heiskala A, Vehmeijer FOL, Lowry E, Caramaschi D, Estrada Gutierrez G, Heiss JA, Hummel N, Keikkala E, Kvist T, Kupsco A, Melton PE, Pesce G, Soomro MH, Vives-Usano M, Baiz N, Binder E, Czamara D, Guxens M, Mustaniemi S, London SJ, Rauschert S, Vääräsmäki M, Vrijheid M, Ziegler AG, Annesi-Maesano I, Bustamante M, Huang RC, Hummel S, Just AC, Kajantie E, Lahti J, Lawlor D, Räikkönen K, Järvelin MR, Felix JF, Sebert S.
PMID: 33331245
Epigenetics. 2021 Jan 11;1-13. doi: 10.1080/15592294.2020.1864171. Epub 2021 Jan 11.

Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by differential DNA methylation in the newborn with possible long-term consequences....

Corrigendum to 'Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children' [Psychoneuroendocrinology 113 March (2020) 104484].

Psychoneuroendocrinology

Marini S, Davis KA, Soare TW, Zhu Y, Suderman MJ, Simpkin AJ, Smith ADAC, Wolf EJ, Relton CL, Dunn EC.
PMID: 32863090
Psychoneuroendocrinology. 2020 Nov;121:104829. doi: 10.1016/j.psyneuen.2020.104829. Epub 2020 Aug 27.

No abstract available.

Population neuroimaging: generation of a comprehensive data resource within the ALSPAC pregnancy and birth cohort.

Wellcome open research

Sharp TH, McBride NS, Howell AE, Evans CJ, Jones DK, Perry G, Dimitriadis SI, Lancaster TM, Zuccolo L, Relton C, Matthews SM, Breeze T, David AS, Drakesmith M, Linden DEJ, Paus T, Walton E.
PMID: 33043145
Wellcome Open Res. 2020 Aug 28;5:203. doi: 10.12688/wellcomeopenres.16060.1. eCollection 2020.

Neuroimaging offers a valuable insight into human brain development by allowing

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.

Molecular psychiatry

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA.
PMID: 26283641
Mol Psychiatry. 2016 Apr;21(4):585. doi: 10.1038/mp.2015.118. Epub 2015 Aug 18.

No abstract available.

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.

Molecular psychiatry

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ, Satterthwaite TD, Wolf DH, Gur RC, Gur RE, Potkin SG, Mathalon DH, Mueller BA, Preda A, Macciardi F, Ehrlich S, Walton E, Hass J, Calhoun VD, Bockholt HJ, Sponheim SR, Shoemaker JM, van Haren NE, Pol HE, Ophoff RA, Kahn RS, Roiz-Santiañez R, Crespo-Facorro B, Wang L, Alpert KI, Jönsson EG, Dimitrova R, Bois C, Whalley HC, McIntosh AM, Lawrie SM, Hashimoto R, Thompson PM, Turner JA.
PMID: 26283641
Mol Psychiatry. 2016 Apr;21(4):585. doi: 10.1038/mp.2015.118. Epub 2015 Aug 18.

No abstract available.

Pubertal onset with adulthood lung function mediated by height growth in adolescence.

ERJ open research

Li L, Zhang H, Holloway JW, Henderson AJ, Ewart S, Relton CL, Arshad SH, Karmaus W.
PMID: 33263047
ERJ Open Res. 2020 Nov 10;6(4). doi: 10.1183/23120541.00535-2020. eCollection 2020 Oct.

BACKGROUND: Age of pubertal onset is associated with height and lung function in adulthood. It is unknown whether height growth in adolescence mediates the association of age at puberty with early adult lung function.METHODS: Data from the Isle of...

The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST).

International journal of epidemiology

Richmond RC, Sharp GC, Herbert G, Atkinson C, Taylor C, Bhattacharya S, Campbell D, Hall M, Kazmi N, Gaunt T, McArdle W, Ring S, Davey Smith G, Ness A, Relton CL.
PMID: 29546377
Int J Epidemiol. 2018 Jun 01;47(3):928-937. doi: 10.1093/ije/dyy032.

BACKGROUND: It has been proposed that maternal folic-acid supplement use may alter the DNA-methylation patterns of the offspring during the in-utero period, which could influence development and later-life health outcomes. Evidence from human studies suggests a role for prenatal...

Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood.

Clinical epigenetics

Sunny SK, Zhang H, Mzayek F, Relton CL, Ring S, Henderson AJ, Ewart S, Holloway JW, Arshad SH.
PMID: 33407823
Clin Epigenetics. 2021 Jan 06;13(1):5. doi: 10.1186/s13148-020-00992-5.

BACKGROUND: The pattern of lung function development from pre-adolescence to adulthood plays a significant role in the pathogenesis of respiratory diseases. Inconsistent findings in genetic studies on lung function trajectories, the importance of DNA methylation (DNA-M), and the critical...

Showing 1 to 12 of 14 entries