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Streamlining the production of proteins for structural biology.

Biophysical reviews

Owens RJ, Gileadi O.
PMID: 31250316
Biophys Rev. 2019 Jun 27;533-534. doi: 10.1007/s12551-019-00565-8. Epub 2019 Jun 27.

No abstract available.

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Owens RJ, Gileadi O. Streamlining the production of proteins for structural biology. Biophys Rev. 2019;533-534doi: 10.1007/s12551-019-00565-8.
Owens, R. J., & Gileadi, O. (2019). Streamlining the production of proteins for structural biology. Biophysical reviews, 533-534. https://doi.org/10.1007/s12551-019-00565-8
Owens, Raymond J, and Gileadi, Opher. "Streamlining the production of proteins for structural biology." Biophysical reviews vol. (2019): 533-534. doi: https://doi.org/10.1007/s12551-019-00565-8
Owens RJ, Gileadi O. Streamlining the production of proteins for structural biology. Biophys Rev. 2019 Jun 27;533-534. doi: 10.1007/s12551-019-00565-8. Epub 2019 Jun 27. PMID: 31250316; PMCID: PMC6682193.
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The structure-function relationship of oncogenic LMTK3.

Science advances

Ditsiou A, Cilibrasi C, Simigdala N, Papakyriakou A, Milton-Harris L, Vella V, Nettleship JE, Lo JH, Soni S, Smbatyan G, Ntavelou P, Gagliano T, Iachini MC, Khurshid S, Simon T, Zhou L, Hassell-Hart S, Carter P, Pearl LH, Owen RL, Owens RJ, Roe SM, Chayen NE, Lenz HJ, Spencer J, Prodromou C, Klinakis A, Stebbing J, Giamas G.
PMID: 33188023
Sci Adv. 2020 Nov 13;6(46). doi: 10.1126/sciadv.abc3099. Print 2020 Nov.

Elucidating signaling driven by lemur tyrosine kinase 3 (LMTK3) could help drug development. Here, we solve the crystal structure of LMTK3 kinase domain to 2.1Å resolution, determine its consensus motif and phosphoproteome, unveiling in vitro and in vivo LMTK3...

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Ditsiou A, Cilibrasi C, Simigdala N, et al. The structure-function relationship of oncogenic LMTK3. Sci Adv. 2020;6(46)doi: 10.1126/sciadv.abc3099.
Ditsiou, A., Cilibrasi, C., Simigdala, N., Papakyriakou, A., Milton-Harris, L., Vella, V., Nettleship, J. E., Lo, J. H., Soni, S., Smbatyan, G., Ntavelou, P., Gagliano, T., Iachini, M. C., Khurshid, S., Simon, T., Zhou, L., Hassell-Hart, S., Carter, P., Pearl, L. H., Owen, R. L., Owens, R. J., Roe, S. M., Chayen, N. E., Lenz, H. J., Spencer, J., Prodromou, C., Klinakis, A., Stebbing, J., & Giamas, G. (2020). The structure-function relationship of oncogenic LMTK3. Science advances, 6(46), . https://doi.org/10.1126/sciadv.abc3099
Ditsiou, Angeliki, et al. "The structure-function relationship of oncogenic LMTK3." Science advances vol. 6,46 (2020). doi: https://doi.org/10.1126/sciadv.abc3099
Ditsiou A, Cilibrasi C, Simigdala N, Papakyriakou A, Milton-Harris L, Vella V, Nettleship JE, Lo JH, Soni S, Smbatyan G, Ntavelou P, Gagliano T, Iachini MC, Khurshid S, Simon T, Zhou L, Hassell-Hart S, Carter P, Pearl LH, Owen RL, Owens RJ, Roe SM, Chayen NE, Lenz HJ, Spencer J, Prodromou C, Klinakis A, Stebbing J, Giamas G. The structure-function relationship of oncogenic LMTK3. Sci Adv. 2020 Nov 13;6(46). doi: 10.1126/sciadv.abc3099. Print 2020 Nov. PMID: 33188023; PMCID: PMC7673765.
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Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase.

Data in brief

Lanyon-Hogg T, Masumoto N, Bodakh G, Konitsiotis AD, Thinon E, Rodgers UR, Owens RJ, Magee AI, Tate EW.
PMID: 27077078
Data Brief. 2016 Feb 10;7:257-81. doi: 10.1016/j.dib.2016.02.012. eCollection 2016 Jun.

In this data article we describe synthetic and characterisation data for four members of the 5-acyl-6,7-dihydrothieno[3,2-c]pyridine (termed "RU-SKI") class of inhibitors of Hedgehog acyltransferase, including associated NMR spectra for final compounds. RU-SKI compounds were selected for synthesis based on...

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Lanyon-Hogg T, Masumoto N, Bodakh G, et al. Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase. Data Brief. 2016;7:257-81doi: 10.1016/j.dib.2016.02.012.
Lanyon-Hogg, T., Masumoto, N., Bodakh, G., Konitsiotis, A. D., Thinon, E., Rodgers, U. R., Owens, R. J., Magee, A. I., & Tate, E. W. (2016). Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase. Data in brief, 7257-81. https://doi.org/10.1016/j.dib.2016.02.012
Lanyon-Hogg, Thomas, et al. "Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase." Data in brief vol. 7 (2016): 257-81. doi: https://doi.org/10.1016/j.dib.2016.02.012
Lanyon-Hogg T, Masumoto N, Bodakh G, Konitsiotis AD, Thinon E, Rodgers UR, Owens RJ, Magee AI, Tate EW. Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferase. Data Brief. 2016 Feb 10;7:257-81. doi: 10.1016/j.dib.2016.02.012. eCollection 2016 Jun. PMID: 27077078; PMCID: PMC4816282.
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IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent.

Science immunology

Hardman CS, Chen YL, Salimi M, Nahler J, Corridoni D, Jagielowicz M, Fonseka CL, Johnson D, Repapi E, Cousins DJ, Barlow JL, McKenzie ANJ, Simmons A, Ogg G.
PMID: 34021026
Sci Immunol. 2021 May 21;6(59). doi: 10.1126/sciimmunol.abe5084.

Cutaneous group 2 innate lymphoid cells (ILC2) are spatially and epigenetically poised to respond to barrier compromise and associated immunological threats. ILC2, lacking rearranged antigen-specific receptors, are primarily activated by damage-associated cytokines and respond with type 2 cytokine production....

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Hardman CS, Chen YL, Salimi M, et al. IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent. Sci Immunol. 2021;6(59)doi: 10.1126/sciimmunol.abe5084.
Hardman, C. S., Chen, Y. L., Salimi, M., Nahler, J., Corridoni, D., Jagielowicz, M., Fonseka, C. L., Johnson, D., Repapi, E., Cousins, D. J., Barlow, J. L., McKenzie, A. N. J., Simmons, A., & Ogg, G. (2021). IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent. Science immunology, 6(59), . https://doi.org/10.1126/sciimmunol.abe5084
Hardman, Clare S, et al. "IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent." Science immunology vol. 6,59 (2021). doi: https://doi.org/10.1126/sciimmunol.abe5084
Hardman CS, Chen YL, Salimi M, Nahler J, Corridoni D, Jagielowicz M, Fonseka CL, Johnson D, Repapi E, Cousins DJ, Barlow JL, McKenzie ANJ, Simmons A, Ogg G. IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent. Sci Immunol. 2021 May 21;6(59). doi: 10.1126/sciimmunol.abe5084. PMID: 34021026; PMCID: PMC7611333.
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Showing 1 to 4 of 4 entries