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Showing 1 to 12 of 31 entries
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Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A.

European journal of organic chemistry

Beaumont S, Ilardi EA, Tappin ND, Zakarian A.
PMID: 21461316
European J Org Chem. 2010 Oct 01;2010(30):5743-5765. doi: 10.1002/ejoc.201000842.

This microreview provides a compilation of synthetic approaches and total syntheses of pinnatoxin A in a survey of the literature up to early 2010. Pinnatoxin A is the first discovered and representative member of a fascinating group of potent...

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Beaumont S, Ilardi EA, Tappin ND, et al. Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A. European J Org Chem. 2010;2010(30):5743-5765doi: 10.1002/ejoc.201000842.
Beaumont, S., Ilardi, E. A., Tappin, N. D., & Zakarian, A. (2010). Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A. European journal of organic chemistry, 2010(30), 5743-5765. https://doi.org/10.1002/ejoc.201000842
Beaumont, Stéphane, et al. "Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A." European journal of organic chemistry vol. 2010,30 (2010): 5743-5765. doi: https://doi.org/10.1002/ejoc.201000842
Beaumont S, Ilardi EA, Tappin ND, Zakarian A. Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A. European J Org Chem. 2010 Oct 01;2010(30):5743-5765. doi: 10.1002/ejoc.201000842. PMID: 21461316; PMCID: PMC3066085.
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Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells.

Clinical and experimental otorhinolaryngology

Lim YC, Cho KW, Kwon HC, Kang SU, Pyun JH, Lee MH, Hwang HS, Kim JH, Lee HN, Choi EC, Kim CH.
PMID: 21217964
Clin Exp Otorhinolaryngol. 2010 Dec;3(4):217-25. doi: 10.3342/ceo.2010.3.4.217. Epub 2010 Dec 22.

OBJECTIVES: To determine whether a novel marine micro-organism with anticancer properties, H31, the metabolic product of Bacillus SW31, has anti-tumor effects on head and neck cancer, and potential for apoptotic-enhancing anti-cancer treatment of affected patients.METHODS: The cell viability and...

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Lim YC, Cho KW, Kwon HC, et al. Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells. Clin Exp Otorhinolaryngol. 2010;3(4):217-25doi: 10.3342/ceo.2010.3.4.217.
Lim, Y. C., Cho, K. W., Kwon, H. C., Kang, S. U., Pyun, J. H., Lee, M. H., Hwang, H. S., Kim, J. H., Lee, H. N., Choi, E. C., & Kim, C. H. (2010). Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells. Clinical and experimental otorhinolaryngology, 3(4), 217-25. https://doi.org/10.3342/ceo.2010.3.4.217
Lim, Young Chang, et al. "Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells." Clinical and experimental otorhinolaryngology vol. 3,4 (2010): 217-25. doi: https://doi.org/10.3342/ceo.2010.3.4.217
Lim YC, Cho KW, Kwon HC, Kang SU, Pyun JH, Lee MH, Hwang HS, Kim JH, Lee HN, Choi EC, Kim CH. Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells. Clin Exp Otorhinolaryngol. 2010 Dec;3(4):217-25. doi: 10.3342/ceo.2010.3.4.217. Epub 2010 Dec 22. PMID: 21217964; PMCID: PMC3010542.
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Use of biosensors as alternatives to current regulatory methods for marine biotoxins.

Sensors (Basel, Switzerland)

Vilariño N, Fonfría ES, Louzao MC, Botana LM.
PMID: 22291571
Sensors (Basel). 2009;9(11):9414-43. doi: 10.3390/s91109414. Epub 2009 Nov 24.

Marine toxins are currently monitored by means of a bioassay that requires the use of many mice, which poses a technical and ethical problem in many countries. With the exception of domoic acid, there is a legal requirement for...

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Vilariño N, Fonfría ES, Louzao MC, et al. Use of biosensors as alternatives to current regulatory methods for marine biotoxins. Sensors (Basel). 2009;9(11):9414-43doi: 10.3390/s91109414.
Vilariño, N., Fonfría, E. S., Louzao, M. C., & Botana, L. M. (2009). Use of biosensors as alternatives to current regulatory methods for marine biotoxins. Sensors (Basel, Switzerland), 9(11), 9414-43. https://doi.org/10.3390/s91109414
Vilariño, Natalia, et al. "Use of biosensors as alternatives to current regulatory methods for marine biotoxins." Sensors (Basel, Switzerland) vol. 9,11 (2009): 9414-43. doi: https://doi.org/10.3390/s91109414
Vilariño N, Fonfría ES, Louzao MC, Botana LM. Use of biosensors as alternatives to current regulatory methods for marine biotoxins. Sensors (Basel). 2009;9(11):9414-43. doi: 10.3390/s91109414. Epub 2009 Nov 24. PMID: 22291571; PMCID: PMC3260648.
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Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins.

Journal of chemical biology

Houssen WE, Lu Z, Edrada-Ebel R, Chatzi C, Tucker SJ, Sepčić K, Turk T, Zovko A, Shen S, Mancini I, Scott RH, Jaspars M.
PMID: 21326630
J Chem Biol. 2010 Feb 17;3(3):113-25. doi: 10.1007/s12154-010-0036-4.

UNLABELLED: Two new large poly-1,3-dodecylpyridinium salts, APS12 and APS12-2 of 12.5- and 14.7-kDa size, respectively, were synthesised and tested for their pore-forming and transfection capabilities in HEK 293 and undifferentiated mouse ES cells using patch-clamp recording, Ca(2+) imaging and...

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Houssen WE, Lu Z, Edrada-Ebel R, et al. Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins. J Chem Biol. 2010;3(3):113-25doi: 10.1007/s12154-010-0036-4.
Houssen, W. E., Lu, Z., Edrada-Ebel, R., Chatzi, C., Tucker, S. J., Sepčić, K., Turk, T., Zovko, A., Shen, S., Mancini, I., Scott, R. H., & Jaspars, M. (2010). Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins. Journal of chemical biology, 3(3), 113-25. https://doi.org/10.1007/s12154-010-0036-4
Houssen, Wael E, et al. "Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins." Journal of chemical biology vol. 3,3 (2010): 113-25. doi: https://doi.org/10.1007/s12154-010-0036-4
Houssen WE, Lu Z, Edrada-Ebel R, Chatzi C, Tucker SJ, Sepčić K, Turk T, Zovko A, Shen S, Mancini I, Scott RH, Jaspars M. Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins. J Chem Biol. 2010 Feb 17;3(3):113-25. doi: 10.1007/s12154-010-0036-4. PMID: 21326630; PMCID: PMC2906715.
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Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins.

Sensors (Basel, Switzerland)

Byrne B, Stack E, Gilmartin N, O'Kennedy R.
PMID: 22408533
Sensors (Basel). 2009;9(6):4407-45. doi: 10.3390/s90604407. Epub 2009 Jun 05.

Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for 'on-site' analysis. Particular...

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Byrne B, Stack E, Gilmartin N, et al. Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins. Sensors (Basel). 2009;9(6):4407-45doi: 10.3390/s90604407.
Byrne, B., Stack, E., Gilmartin, N., & O'Kennedy, R. (2009). Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins. Sensors (Basel, Switzerland), 9(6), 4407-45. https://doi.org/10.3390/s90604407
Byrne, Barry, et al. "Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins." Sensors (Basel, Switzerland) vol. 9,6 (2009): 4407-45. doi: https://doi.org/10.3390/s90604407
Byrne B, Stack E, Gilmartin N, O'Kennedy R. Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins. Sensors (Basel). 2009;9(6):4407-45. doi: 10.3390/s90604407. Epub 2009 Jun 05. PMID: 22408533; PMCID: PMC3291918.
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Tetrodotoxin Framework Construction from Linear Substrates Utilizing a Hg(OTf).

Organic letters

Nishikawa K, Noguchi T, Kikuchi S, Maruyama T, Araki Y, Yotsu-Yamashita M, Morimoto Y.
PMID: 33577338
Org Lett. 2021 Mar 05;23(5):1703-1708. doi: 10.1021/acs.orglett.1c00125. Epub 2021 Feb 12.

In this contribution, we propose a new synthetic approach to tetrodotoxin (TTX), one of the most famous marine toxins that, after first preparing a functionalized linear substrate, forms a cyclohexane core from the substrate utilizing our mercuric triflate (Hg(OTf)

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Nishikawa K, Noguchi T, Kikuchi S, et al. Tetrodotoxin Framework Construction from Linear Substrates Utilizing a Hg(OTf). Org Lett. 2021;23(5):1703-1708doi: 10.1021/acs.orglett.1c00125.
Nishikawa, K., Noguchi, T., Kikuchi, S., Maruyama, T., Araki, Y., Yotsu-Yamashita, M., & Morimoto, Y. (2021). Tetrodotoxin Framework Construction from Linear Substrates Utilizing a Hg(OTf). Organic letters, 23(5), 1703-1708. https://doi.org/10.1021/acs.orglett.1c00125
Nishikawa, Keisuke, et al. "Tetrodotoxin Framework Construction from Linear Substrates Utilizing a Hg(OTf)." Organic letters vol. 23,5 (2021): 1703-1708. doi: https://doi.org/10.1021/acs.orglett.1c00125
Nishikawa K, Noguchi T, Kikuchi S, Maruyama T, Araki Y, Yotsu-Yamashita M, Morimoto Y. Tetrodotoxin Framework Construction from Linear Substrates Utilizing a Hg(OTf). Org Lett. 2021 Mar 05;23(5):1703-1708. doi: 10.1021/acs.orglett.1c00125. Epub 2021 Feb 12. PMID: 33577338.
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Current research progress of mammalian cell-based biosensors on the detection of foodborne pathogens and toxins.

Critical reviews in food science and nutrition

Lu X, Ye Y, Zhang Y, Sun X.
PMID: 32885986
Crit Rev Food Sci Nutr. 2020 Sep 04;1-17. doi: 10.1080/10408398.2020.1809341. Epub 2020 Sep 04.

Foodborne diseases caused by pathogens and toxins are a serious threat to food safety and human health; thus, they are major concern to society. Existing conventional foodborne pathogen or toxin detection methods, including microbiological assay, nucleic acid-based assays, immunological...

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Lu X, Ye Y, Zhang Y, et al. Current research progress of mammalian cell-based biosensors on the detection of foodborne pathogens and toxins. Crit Rev Food Sci Nutr. 2020;1-17doi: 10.1080/10408398.2020.1809341.
Lu, X., Ye, Y., Zhang, Y., & Sun, X. (2020). Current research progress of mammalian cell-based biosensors on the detection of foodborne pathogens and toxins. Critical reviews in food science and nutrition, 1-17. https://doi.org/10.1080/10408398.2020.1809341
Lu, Xin, et al. "Current research progress of mammalian cell-based biosensors on the detection of foodborne pathogens and toxins." Critical reviews in food science and nutrition vol. (2020): 1-17. doi: https://doi.org/10.1080/10408398.2020.1809341
Lu X, Ye Y, Zhang Y, Sun X. Current research progress of mammalian cell-based biosensors on the detection of foodborne pathogens and toxins. Crit Rev Food Sci Nutr. 2020 Sep 04;1-17. doi: 10.1080/10408398.2020.1809341. Epub 2020 Sep 04. PMID: 32885986.
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The isolation of water-soluble natural products - challenges, strategies and perspectives.

Natural product reports

Berlinck RGS, Crnkovic CM, Gubiani JR, Bernardi DI, Ióca LP, Quintana-Bulla JI.
PMID: 34647117
Nat Prod Rep. 2021 Oct 14; doi: 10.1039/d1np00037c. Epub 2021 Oct 14.

Covering period: up to 2019Water-soluble natural products constitute a relevant group of secondary metabolites notably known for presenting potent biological activities. Examples are aminoglycosides, β-lactam antibiotics, saponins of both terrestrial and marine origin, and marine toxins. Although extensively investigated...

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Berlinck RGS, Crnkovic CM, Gubiani JR, et al. The isolation of water-soluble natural products - challenges, strategies and perspectives. Nat Prod Rep. 2021;doi: 10.1039/d1np00037c.
Berlinck, R. G. S., Crnkovic, C. M., Gubiani, J. R., Bernardi, D. I., Ióca, L. P., & Quintana-Bulla, J. I. (2021). The isolation of water-soluble natural products - challenges, strategies and perspectives. Natural product reports, . https://doi.org/10.1039/d1np00037c
Berlinck, Roberto G S, et al. "The isolation of water-soluble natural products - challenges, strategies and perspectives." Natural product reports vol. (2021). doi: https://doi.org/10.1039/d1np00037c
Berlinck RGS, Crnkovic CM, Gubiani JR, Bernardi DI, Ióca LP, Quintana-Bulla JI. The isolation of water-soluble natural products - challenges, strategies and perspectives. Nat Prod Rep. 2021 Oct 14; doi: 10.1039/d1np00037c. Epub 2021 Oct 14. PMID: 34647117.
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Ensuring seafood safe to spoon: a brief review of biosensors for marine biotoxin monitoring.

Critical reviews in food science and nutrition

Wang Q, Yang Q, Wu W.
PMID: 33287557
Crit Rev Food Sci Nutr. 2020 Dec 08;1-13. doi: 10.1080/10408398.2020.1854170. Epub 2020 Dec 08.

With harmful algal blooms, marine food poisoning caused by marine biotoxins frequently occurs and is life-threatening if severe. However, the conventional detection methods of marine toxins have a few limitations: low sensitivity and high-cost. Therefore, it is necessary to...

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Wang Q, Yang Q, Wu W. Ensuring seafood safe to spoon: a brief review of biosensors for marine biotoxin monitoring. Crit Rev Food Sci Nutr. 2020;1-13doi: 10.1080/10408398.2020.1854170.
Wang, Q., Yang, Q., & Wu, W. (2020). Ensuring seafood safe to spoon: a brief review of biosensors for marine biotoxin monitoring. Critical reviews in food science and nutrition, 1-13. https://doi.org/10.1080/10408398.2020.1854170
Wang, Qi, et al. "Ensuring seafood safe to spoon: a brief review of biosensors for marine biotoxin monitoring." Critical reviews in food science and nutrition vol. (2020): 1-13. doi: https://doi.org/10.1080/10408398.2020.1854170
Wang Q, Yang Q, Wu W. Ensuring seafood safe to spoon: a brief review of biosensors for marine biotoxin monitoring. Crit Rev Food Sci Nutr. 2020 Dec 08;1-13. doi: 10.1080/10408398.2020.1854170. Epub 2020 Dec 08. PMID: 33287557.
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Role of Biomarkers in Monitoring Brevetoxins in .

Food safety (Tokyo, Japan)

Abraham A, El Said KR, Flewelling LJ.
PMID: 32231945
Food Saf (Tokyo). 2018 Mar 30;6(1):33-43. doi: 10.14252/foodsafetyfscj.2017021. eCollection 2018 Mar.

Monitoring and management programs for marine toxins in seafood depend on efficient detection tools for their success in protecting public health. Here we review current methods of detection for neurotoxic shellfish poisoning (NSP) toxins, and current knowledge in brevetoxin...

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Abraham A, El Said KR, Flewelling LJ. Role of Biomarkers in Monitoring Brevetoxins in . Food Saf (Tokyo). 2018;6(1):33-43doi: 10.14252/foodsafetyfscj.2017021.
Abraham, A., El Said, K. R., & Flewelling, L. J. (2018). Role of Biomarkers in Monitoring Brevetoxins in . Food safety (Tokyo, Japan), 6(1), 33-43. https://doi.org/10.14252/foodsafetyfscj.2017021
Abraham, Ann, et al. "Role of Biomarkers in Monitoring Brevetoxins in ." Food safety (Tokyo, Japan) vol. 6,1 (2018): 33-43. doi: https://doi.org/10.14252/foodsafetyfscj.2017021
Abraham A, El Said KR, Flewelling LJ. Role of Biomarkers in Monitoring Brevetoxins in . Food Saf (Tokyo). 2018 Mar 30;6(1):33-43. doi: 10.14252/foodsafetyfscj.2017021. eCollection 2018 Mar. PMID: 32231945; PMCID: PMC6989187.
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Progress on the investigation and monitoring of marine phycotoxins in China.

Harmful algae

Liang Y, Li A, Chen J, Tan Z, Tong M, Liu Z, Qiu J, Yu R.
PMID: 35016765
Harmful Algae. 2022 Jan;111:102152. doi: 10.1016/j.hal.2021.102152. Epub 2021 Dec 09.

Marine phycotoxins associated with paralytic shellfish poisoning (PSP), diarrhetic shellfish poisoning (DSP), amnesic shellfish poisoning (ASP), neurotoxic shellfish poisoning (NSP), ciguatera fish poisoning (CFP), tetrodotoxin (TTX), palytoxin (PLTX) and neurotoxin β-N-methylamino-L-alanine (BMAA) have been investigated and routinely monitored along...

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Liang Y, Li A, Chen J, et al. Progress on the investigation and monitoring of marine phycotoxins in China. Harmful Algae. 2021;111:102152doi: 10.1016/j.hal.2021.102152.
Liang, Y., Li, A., Chen, J., Tan, Z., Tong, M., Liu, Z., Qiu, J., & Yu, R. (2022). Progress on the investigation and monitoring of marine phycotoxins in China. Harmful algae, 111102152. https://doi.org/10.1016/j.hal.2021.102152
Liang, Yubo, et al. "Progress on the investigation and monitoring of marine phycotoxins in China." Harmful algae vol. 111 (2022): 102152. doi: https://doi.org/10.1016/j.hal.2021.102152
Liang Y, Li A, Chen J, Tan Z, Tong M, Liu Z, Qiu J, Yu R. Progress on the investigation and monitoring of marine phycotoxins in China. Harmful Algae. 2022 Jan;111:102152. doi: 10.1016/j.hal.2021.102152. Epub 2021 Dec 09. PMID: 35016765.
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Tetrodotoxin in live bivalve mollusks from Europe: Is it to be considered an emerging concern for food safety?.

Comprehensive reviews in food science and food safety

Antonelli P, Salerno B, Bordin P, Peruzzo A, Orsini M, Arcangeli G, Barco L, Losasso C.
PMID: 34954887
Compr Rev Food Sci Food Saf. 2021 Dec 26; doi: 10.1111/1541-4337.12881. Epub 2021 Dec 26.

Tetrodotoxins (TTXs) are a group of potent neurotoxins named after the Tetraodontidae fish family (pufferfish). TTXs have been reported in several animal taxa, both terrestrial and marine. The ingestion of TTX-contaminated flesh can cause serious neurotoxic symptomatology and can...

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Antonelli P, Salerno B, Bordin P, et al. Tetrodotoxin in live bivalve mollusks from Europe: Is it to be considered an emerging concern for food safety?. Compr Rev Food Sci Food Saf. 2021;doi: 10.1111/1541-4337.12881.
Antonelli, P., Salerno, B., Bordin, P., Peruzzo, A., Orsini, M., Arcangeli, G., Barco, L., & Losasso, C. (2021). Tetrodotoxin in live bivalve mollusks from Europe: Is it to be considered an emerging concern for food safety?. Comprehensive reviews in food science and food safety, . https://doi.org/10.1111/1541-4337.12881
Antonelli, Pietro, et al. "Tetrodotoxin in live bivalve mollusks from Europe: Is it to be considered an emerging concern for food safety?." Comprehensive reviews in food science and food safety vol. (2021). doi: https://doi.org/10.1111/1541-4337.12881
Antonelli P, Salerno B, Bordin P, Peruzzo A, Orsini M, Arcangeli G, Barco L, Losasso C. Tetrodotoxin in live bivalve mollusks from Europe: Is it to be considered an emerging concern for food safety?. Compr Rev Food Sci Food Saf. 2021 Dec 26; doi: 10.1111/1541-4337.12881. Epub 2021 Dec 26. PMID: 34954887.
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Showing 1 to 12 of 31 entries