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Showing 1 to 12 of 25 entries
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Detection of weak hydrogen bonding to fluoro and nitro groups in solution using H/D exchange.

Organic & biomolecular chemistry

Shugrue CR, DeFrancisco JR, Metrano AJ, Brink BD, Nomoto RS, Linton BR.
PMID: 26782121
Org Biomol Chem. 2016 Feb 21;14(7):2223-7. doi: 10.1039/c5ob02360b. Epub 2016 Jan 19.

Hydrogen/deuterium (H/D) exchange can be a sensitive technique for measuring the strength of hydrogen bonding to neutral organic nitro and fluoro groups. The slower rates of reaction in comparison to suitable controls suggest that hydrogen bonding is present, albeit...

Influence of enovid on the cytopathic action of staphylococcal alpha toxin.

Infection and immunity

Yotis W, Savov Z.
PMID: 16557707
Infect Immun. 1970 Feb;1(2):157-63. doi: 10.1128/iai.1.2.157-163.1970.

The effect of the widely employed oral contraceptive steroid, Enovid, on the cytolytic action of the staphylococcal alpha toxin was investigated as an extension of previous studies in which it was shown that steroids were capable of suppressing induced...

Hormonal therapy for suppressing lactation.

Canadian family physician Medecin de famille canadien

Balmer HC, Macdonald DJ.
PMID: 20468683
Can Fam Physician. 1971 Sep;17(9):54-5.

In recent years, hormonal suppression of undesired lactation has been widely employed. A review of the literature confirms the efficacy of this method, at first with estrogen alone and later with progestogen-estrogen combinations. The authors also discuss retrospective studies...

Mild Synthesis of Sterically Congested Alkyl Aryl Ethers.

Organic letters

Lindstedt E, Stridfeldt E, Olofsson B.
PMID: 27529124
Org Lett. 2016 Aug 16; Epub 2016 Aug 16.

An efficient and transition-metal-free method is presented to access tertiary alkyl aryl ethers by arylation of tertiary alcohols with ortho-substituted diaryliodonium salts. The scope covers cyclic and acyclic aliphatic, benzylic, allylic, and propargylic tertiary alcohols as well as primary...

ICD-10 Diagnostic Coding for Identifying Hospitalizations Related to a Diabetic Foot Ulcer.

Clinical and investigative medicine. Medecine clinique et experimentale

Syed MH, Al-Omran M, Jacob-Brassard J, Ray JG, Hussain MA, Mamdani M, Mestral C.
PMID: 34978770
Clin Invest Med. 2021 Dec 31;44(4):E11-16. doi: 10.25011/cim.v44i4.37592.

PURPOSE: To estimate the positive predictive value (PPV) of Canadian ICD-10 diagnostic coding for the identification of hospitalization related to a diabetic foot ulcer (DFU).METHODS: Hospitalizations related to a neuropathic and/or ischemic DFU were identified from the Discharge Abstract...

Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides.

ACS catalysis

Stone EA, Hosseinzadeh P, Craven TW, Robertson MJ, Han Y, Hsieh SY, Metrano AJ, Baker D, Miller SJ.
PMID: 34659874
ACS Catal. 2021 Apr 16;11(8):4395-4400. doi: 10.1021/acscatal.1c01097. Epub 2021 Mar 25.

Studying the relationship between catalyst conformational dynamics and selectivity in an asymmetric reaction is a challenge. In this study, cyclic peptides were computationally designed to stabilize different ground state conformations of a highly effective, flexible tetrapeptide catalyst for the...

Diversity-oriented synthesis of 17-spirosteroids.

Beilstein journal of organic chemistry

Laroche B, Bouvarel T, Louis-Sylvestre M, Nay B.
PMID: 32461769
Beilstein J Org Chem. 2020 Apr 28;16:880-887. doi: 10.3762/bjoc.16.79. eCollection 2020.

A diversity-oriented synthesis (DOS) approach has been used to functionalize 17-ethynyl-17-hydroxysteroids through a one-pot procedure involving a ring-closing enyne metathesis (RCEYM) and a Diels-Alder reaction on the resulting diene, under microwave irradiations. Taking advantage of the propargyl alcohol moiety...

Thermodynamic evaluation of aromatic CH/π interactions and rotational entropy in a molecular rotor.

Journal of the American Chemical Society

Pérez-Estrada S, Rodríguez-Molina B, Xiao L, Santillan R, Jiménez-Osés G, Houk KN, Garcia-Garibay MA.
PMID: 25635355
J Am Chem Soc. 2015 Feb 18;137(6):2175-8. doi: 10.1021/ja512053t. Epub 2015 Feb 04.

A molecular rotor built with a stator formed by two rigid 9β-mestranol units having a 90° bent angle linked to a central phenylene rotator has an ideal structure to examine aromatic CH/π interactions. Energies and populations of the multiple...

Nanorod based Schottky contact gas sensors in reversed bias condition.

Nanotechnology

Yu J, Ippolito SJ, Wlodarski W, Strano M, Kalantar-zadeh K.
PMID: 20534895
Nanotechnology. 2010 Jul 02;21(26):265502. doi: 10.1088/0957-4484/21/26/265502. Epub 2010 Jun 10.

There has been significant interest in using electronically contacted nanorod or nanotube arrays as gas sensors, whereby an adsorbate modifies either the impedance or the Fermi level of the array, enabling detection. Typically, such arrays demonstrate the I-V curves...

Shape-matching soft mechanical metamaterials.

Scientific reports

Mirzaali MJ, Janbaz S, Strano M, Vergani L, Zadpoor AA.
PMID: 29343772
Sci Rep. 2018 Jan 17;8(1):965. doi: 10.1038/s41598-018-19381-3.

Architectured materials with rationally designed geometries could be used to create mechanical metamaterials with unprecedented or rare properties and functionalities. Here, we introduce "shape-matching" metamaterials where the geometry of cellular structures comprising auxetic and conventional unit cells is designed...

ICD-10 Diagnostic Coding for Identifying Hospitalizations Related to a Diabetic Foot Ulcer.

Clinical and investigative medicine. Medecine clinique et experimentale

Syed MH, Al-Omran M, Jacob-Brassard J, Ray JG, Hussain MA, Mamdani M, Mestral C.
PMID: 34978770
Clin Invest Med. 2021 Dec 31;44(4):E11-16. doi: 10.25011/cim.v44i4.37592.

PURPOSE: To estimate the positive predictive value (PPV) of Canadian ICD-10 diagnostic coding for the identification of hospitalization related to a diabetic foot ulcer (DFU).METHODS: Hospitalizations related to a neuropathic and/or ischemic DFU were identified from the Discharge Abstract...

Viscosity studies on Mestranol.

Pakistan journal of pharmaceutical sciences

Akhtar S, Ahmad T, Hassan F, Arif M, Hassan S.
PMID: 16414812
Pak J Pharm Sci. 1998 Jul;11(2):1-4.

The viscosity of 1x10(-4) M to 4x10(-4) M solution of Mestranol (synthetic oestrogenic steroidal hormone) in ethanol was measured at 32 degrees, 40 degrees and 50 degrees C in a viscometric bath. The viscosity rates are maximum at 30...

Showing 1 to 12 of 25 entries